Find hotels in Downtown South San Francisco, San Francisco

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Our top choices for Downtown South San Francisco hotels

Miller Apartments

Miller Apartments
2.0 star property
Downtown South San Francisco
7.0 out of 10, Good, (16 reviews)
"Own bedroom was quiet and tidy, shared bathroom clean and tidy, good communication "
Australia
Kasey
The price is NT$1,956
NT$4,708 total
includes taxes & fees
Apr 7 - Apr 8
Miller Apartments

Airport Inn

Airport Inn
2.0 star property
Downtown South San Francisco
8.8 out of 10, Excellent, (1,001 reviews)
"excellent and very clean"
United States
George
The price is NT$3,308
NT$3,875 total
includes taxes & fees
Apr 10 - Apr 11
Airport Inn

La Quinta Inn & Suites by Wyndham San Francisco Airport N

La Quinta Inn & Suites by Wyndham San Francisco Airport N
3.0 star property
Downtown South San Francisco
8.2 out of 10, Very Good, (1,967 reviews)
"Great place to stay!"
United States
Alma
The price is NT$3,483
NT$4,085 total
includes taxes & fees
Apr 12 - Apr 13
La Quinta Inn & Suites by Wyndham San Francisco Airport N

Inn By The SFO

Inn By The SFO
2.0 star property
Downtown South San Francisco
7.8 out of 10, Good, (1,001 reviews)
"Perfect for quick stays! Clean, safe and affordable! "
United States
carlos
The price is NT$2,816
NT$3,311 total
includes taxes & fees
Apr 7 - Apr 8
Inn By The SFO

Hilton San Francisco Airport Bayfront

Hilton San Francisco Airport Bayfront
4.0 star property
9.9 km from Downtown South San Francisco
8.6 out of 10, Excellent, (2,940 reviews)
"Convenient location close to the airport. The hotel was nice and excellent staff."
United States
Shawna
The price is NT$3,499
NT$3,978 total
includes taxes & fees
Apr 12 - Apr 13
Hilton San Francisco Airport Bayfront

Good Nite Inn - Redwood City

Good Nite Inn - Redwood City
2.5 star property
23.9 km from Downtown South San Francisco
8.6 out of 10, Excellent, (1,729 reviews)
"Always great staying here while traveling for work, the receptionists and housekeepers are all great! "
United States
Mourine
The price is NT$2,876
NT$3,249 total
includes taxes & fees
Apr 7 - Apr 8
Good Nite Inn - Redwood City

DoubleTree by Hilton San Francisco Airport

DoubleTree by Hilton San Francisco Airport
4.0 star property
9.3 km from Downtown South San Francisco
8.6 out of 10, Excellent, (1,495 reviews)
"Very nice hotel, clean, Starbucks onsite, and great breakfast choices."
United States
Fritz Lou
The price is NT$2,879
NT$3,273 total
includes taxes & fees
Apr 12 - Apr 13
DoubleTree by Hilton San Francisco Airport

The Marina Inn on San Francisco Bay

The Marina Inn on San Francisco Bay
3.5 star property
20.5 km from Downtown South San Francisco
8.6 out of 10, Excellent, (2,379 reviews)
"The staff was excelent with us and good food."
United States
Walkiria
The price is NT$3,065
NT$3,494 total
includes taxes & fees
Apr 10 - Apr 11
The Marina Inn on San Francisco Bay

Vagabond Inn Executive San Francisco Airport

Vagabond Inn Executive San Francisco Airport
2.5 star property
7.6 km from Downtown South San Francisco
8.0 out of 10, Very Good, (1,004 reviews)
"Friendly staff, clean rooms, all the conveniences needed to make the stay great! "
United States
Justina
The price is NT$3,036
NT$3,429 total
includes taxes & fees
Apr 11 - Apr 12
Vagabond Inn Executive San Francisco Airport

Hotel Riu Plaza Fisherman's Wharf

Hotel Riu Plaza Fisherman's Wharf
4.0 star property
16.8 km from Downtown South San Francisco
9.0 out of 10, Wonderful, (7,390 reviews)
"Loved location, kind staff, parking, clean and comfy rooms plus a decent breakfast!"
United States
Debra
The price is NT$4,217
NT$6,280 total
includes taxes & fees
Apr 20 - Apr 21
Hotel Riu Plaza Fisherman's Wharf

Hotel Garrett

Hotel Garrett
3.0 star property
13.6 km from Downtown South San Francisco
7.8 out of 10, Good, (825 reviews)
"Great place."
United States
Abhinav
The price is NT$2,272
NT$3,313 total
includes taxes & fees
Apr 12 - Apr 13
Hotel Garrett

The Dylan at SFO

The Dylan at SFO
3.0 star property
7.1 km from Downtown South San Francisco
9.2 out of 10, Wonderful, (1,848 reviews)
"The place was cozy, super clean and coffee was the best ever."
United States
Aurora
The price is NT$3,810
NT$4,524 total
includes taxes & fees
Apr 10 - Apr 11
The Dylan at SFO

LUMA Hotel San Francisco

LUMA Hotel San Francisco
4.0 star property
13.3 km from Downtown South San Francisco
9.6 out of 10, Exceptional, (2,441 reviews)
"Excellent hotel "
United States
Alexis
The price is NT$6,999
NT$8,237 total
includes taxes & fees
Apr 18 - Apr 19
LUMA Hotel San Francisco

Holiday Inn Express Hotel & Suites Oakland-Airport by IHG

Holiday Inn Express Hotel & Suites Oakland-Airport by IHG
2.5 star property
20.7 km from Downtown South San Francisco
8.8 out of 10, Excellent, (1,004 reviews)
"Everything was great!"
United States
Shalonda
The price is NT$4,282
NT$5,347 total
includes taxes & fees
Apr 10 - Apr 11
Holiday Inn Express Hotel & Suites Oakland-Airport by IHG

Soma House

Soma House
3.5 star property
13.6 km from Downtown South San Francisco
7.6 out of 10, Good, (952 reviews)
"Nice place, friendly staff clean room"
United States
Todd
The price is NT$2,560
NT$3,652 total
includes taxes & fees
Apr 10 - Apr 11
Soma House

Hotel Zoe Fisherman's Wharf

Hotel Zoe Fisherman's Wharf
4.0 star property
16.6 km from Downtown South San Francisco
9.2 out of 10, Wonderful, (1,790 reviews)
"Great location, friendly staff, nice rooms. "
Australia
Clyden
The price is NT$3,264
NT$5,196 total
includes taxes & fees
Apr 20 - Apr 21
Hotel Zoe Fisherman's Wharf

DoubleTree by Hilton Hotel Berkeley Marina

DoubleTree by Hilton Hotel Berkeley Marina
4.0 star property
25.2 km from Downtown South San Francisco
8.2 out of 10, Very Good, (4,442 reviews)
"I love staying here. The location is beautiful and serene while the rooms are well taken care of. "
United States
Marisa
The price is NT$4,366
NT$5,029 total
includes taxes & fees
Apr 12 - Apr 13
DoubleTree by Hilton Hotel Berkeley Marina

Hotel Zephyr San Francisco

Hotel Zephyr San Francisco
4.0 star property
16.8 km from Downtown South San Francisco
8.6 out of 10, Excellent, (2,500 reviews)
"Great location "
United States
Ramona
The price is NT$4,591
NT$6,719 total
includes taxes & fees
Apr 20 - Apr 21
Hotel Zephyr San Francisco

Hotel Aura SFO

Hotel Aura SFO
3.0 star property
4.4 km from Downtown South San Francisco
9.0 out of 10, Wonderful, (2,613 reviews)
"The location, clean room and friendly staff would stay here again"
United States
Allyson
The price is NT$3,135
NT$3,757 total
includes taxes & fees
Apr 12 - Apr 13
Hotel Aura SFO

Cow Hollow Inn & Suites

Cow Hollow Inn & Suites
3.5 star property
16 km from Downtown South San Francisco
9.2 out of 10, Wonderful, (1,555 reviews)
"Perfect location and friendly staff Would go again"
United Kingdom
Mrs Meeta
The price is NT$3,844
NT$4,471 total
includes taxes & fees
Apr 12 - Apr 13
Cow Hollow Inn & Suites
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Downtown South San Francisco

Find the best Downtown South San Francisco areas and neighborhoods for the activities you enjoy most.

Fisherman's Wharf

Discover Pier 39, Ghirardelli Square, and the San Francisco Maritime National Historical Park in this bustling tourist hotspot. Savor seafood at family-owned restaurants and explore the sea lion colony, while enjoying convenient cable car access.

Union Square

Major tourist destination in downtown San Francisco, Union Square boasts shopping, hotels, and theaters. Explore department stores, boutiques, and galleries, or catch a performance at various theaters. Enjoy the Dewey Monument and stunning views from nearby hotels. Easily accessible via cable car lines, buses, and subway systems.

Downtown San Francisco

Serving as San Francisco's central business district, this area boasts Northern California's two tallest buildings, the Salesforce Tower and Transamerica Pyramid. Explore shopping malls like the Embarcadero Center and enjoy parks such as Sue Biermann Park, all easily accessible via Muni bus and rail lines.

North Beach

Adjacent to Chinatown and the Financial District, this "Little Italy" boasts Italian restaurants, cafes, and bakeries along Columbus Avenue and Washington Square. Explore the National Shrine of Saint Francis of Assisi and City Lights Bookstore.

Nob Hill

Luxury hotels, historic mansions, and Michelin-starred restaurants abound in this upscale area. Explore Union Square shopping district, Grace Cathedral, and the SF Masonic Auditorium for a taste of culture and history.

Top Downtown South San Francisco Hotel Reviews

Frequently asked questions

What's it like in Downtown South San Francisco?
You'll be sure to have fun visiting South San Francisco's Downtown South San Francisco neighborhood.
What's a favorite place to stay in Downtown South San Francisco?
Based on Expedia customer reviews, Inn By The SFO is a highly ranked property in Downtown South San Francisco. This hotel offers free parking and free WiFi. Other favorite options in the area include Airport Inn and La Quinta Inn & Suites by Wyndham San Francisco Airport N.
How many hotels will I find in the Downtown South San Francisco area?
When you want to kick up your feet after a day of exploring the sights in South San Francisco, you can choose from 13 Expedia hotels and other accommodations in Downtown South San Francisco.
If I need to cancel my hotel reservation in Downtown South San Francisco, will I receive a refund?
Yes, the majority of room reservations are refundable provided that you cancel before the accommodation's cancellation deadline, which in most cases is within 24 or 48 hours of the scheduled arrival. If you have a reservation that's non-refundable, it might still be possible to cancel it and be given a refund within a 24-hour period of your booking. Enter dates in and click on "Search", then you can use the "fully refundable" filter to get the best deals available in Downtown South San Francisco.
Where can I learn more about changing or cancelling my trip to Downtown South San Francisco?
To find more details about picking new dates or cancelling your trip to Downtown South San Francisco, head over to our customer service page.
What can I see and do in this South San Francisco neighborhood?
South San Francisco Hillside Sign, Sign Hill Park, and See's Candies are just a few of the places to visit in and around Downtown South San Francisco. Cinemark Century at Tanforan and K1 Speed are also worth a visit when you're out sightseeing in South San Francisco.

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