A red train on tracks, palm trees, and modern buildings.

Independent Central San Diego hotels

  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in
  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Tonight
Aug 26 - Aug 27
Tomorrow
Aug 27 - Aug 28
This weekend
Aug 28 - Aug 30
Next weekend
Sep 4 - Sep 6
Save an average of 15% on thousands of hotels when you're signed in

Top Central San Diego Hotel Reviews

San Diego Marriott Mission Valley

San Diego Marriott Mission Valley

8/10 Good
"The location of this hotel was great. It was near a shopping center and close to the freeway. The parking was a little challenging because the spaces are really small. Many people would take up 2 spaces, but found out our last night there is overflow parking in the back of the hotel. Our first night none of our outlets were working, including a refrigerator. We had to charge our phones in the bathroom. I called the front desk in the morning and they sent someone up right away. The maintenance worker checked the outlets and fixed them. The staff was really friendly and helpful even with"
Eileen 2-night trip
Posted 1 hour ago
San Diego Marriott Mission Valley
Days Inn by Wyndham San Diego Hotel Circle

Days Inn by Wyndham San Diego Hotel Circle

8/10 Good
"Room was clean, betting was clean and comfortable. The shower needs an updating Tile grout has stains. fixtures are quite old. Bathroom area needs an updating. The carpet to the entry door does not seal completely. Light was coming through. Had to use a towel to block lighting. Window could also use better darkening curtains. Other guests close to us coming in and out letting go of the door which caused a loud slam. Woke us up a couple times at night. Also late night talking outside was not good."
Myrna 3-night trip
Posted 2 hours ago
Days Inn by Wyndham San Diego Hotel Circle
DoubleTree by Hilton Hotel San Diego - Mission Valley

DoubleTree by Hilton Hotel San Diego - Mission Valley

10/10 Excellent
"The property was well maintaned, we were allowed to check in a tad it early which was amazing. Parking was good, and the onsite restaurant was amazing."
Juan 1-night trip
Posted 11 hours ago
DoubleTree by Hilton Hotel San Diego - Mission Valley
California Suites Hotel

California Suites Hotel

10/10 Excellent
"The room was clean but there was no bath mat in the shower"
Arlene 1-night trip
Posted 12 hours ago
California Suites Hotel
The Alcala Hotel Mission Valley/Seaworld

The Alcala Hotel Mission Valley/Seaworld

8/10 Good
"The welcome from the staff on the front desk was amazing. The were very helpful in sorting a couple of administrative issues we had and got our party checked in, in very quick time. The room was everything we needed for 1 night and the perfect location for the shopping mall/food and also the attractions down at the dock area. The best and most surprising element of the hotel was the variety and quality of the breakfast."
Colin 1-night trip
Posted 13 hours ago
The Alcala Hotel Mission Valley/Seaworld
Pleasant Inn

Pleasant Inn

10/10 Excellent
"All good."
Seda 2-night trip
Posted 15 hours ago
Pleasant Inn
Kings Inn San Diego

Kings Inn San Diego

10/10 Excellent
"Family Run Property, the staff is good about reminding you of that. Well appointed location with two restaurants onsite (am & pm), and a convenient store within an easy walk with the 88 hotel loop out the front door."
Jean 3-night trip
Posted 16 hours ago
Kings Inn San Diego
Best Western Inn & Suites San Diego – Zoo/SeaWorld Area

Best Western Inn & Suites San Diego – Zoo/SeaWorld Area

8/10 Good
"The Best Western was convenient to everything we wanted to do so that was a huge plus. The staff was excellent. The complimentary breakfast was decent especially when comparing to other establishments. The only thing that I would have changed was the comfort of the bed and pillows."
KELLEE 6-night trip
Posted 17 hours ago
Best Western Inn & Suites San Diego – Zoo/SeaWorld Area
Lafayette Hotel & Club

Lafayette Hotel & Club

8/10 Good
"Only 1 robe for 2 people in the room. For coffee, no sweetner or sugar or creamer. There was no shower gel, container was empty."
Elin 2-night trip
Posted 20 hours ago
Lafayette Hotel & Club

Explore a world of travel with Expedia