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Our top choices for Rochester hotels

1. Hyatt House Rochester/Mayo Clinic Area
Hyatt House Rochester/Mayo Clinic Area
2. TownePlace Suites by Marriott Rochester Mayo Clinic Area
TownePlace Suites by Marriott Rochester Mayo Clinic Area
3. Home2 Suites by Hilton Rochester Mayo Clinic Area
Home2 Suites by Hilton Rochester Mayo Clinic Area
4. Hilton Rochester Mayo Clinic Area
Hilton Rochester Mayo Clinic Area
5. Holiday Inn Express Rochester South - Mayo Area by IHG
Holiday Inn Express Rochester South - Mayo Area by IHG
6. Hampton Inn & Suites Rochester-North
Hampton Inn & Suites Rochester-North
7. Fairfield Inn & Suites Rochester Mayo Clinic Area/St. Marys
Fairfield Inn & Suites Rochester Mayo Clinic Area/St. Marys
8. Brentwood Inn & Suites
Brentwood Inn & Suites
9. EVEN Hotel Rochester - Mayo Clinic Area by IHG
EVEN Hotel Rochester - Mayo Clinic Area by IHG
10. Econo Lodge Mayo Clinic Area
Econo Lodge Mayo Clinic Area
11. Comfort Inn & Suites Rochester South Mayo Clinic
Comfort Inn & Suites Rochester South Mayo Clinic
12. SpringHill Suites by Marriott Rochester-Mayo Clinic/St Marys
SpringHill Suites by Marriott Rochester-Mayo Clinic/St Marys
13. Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area
Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area
14. AmericInn by Wyndham Rochester Near Mayo Clinic
AmericInn by Wyndham Rochester Near Mayo Clinic
15. Holiday Inn Express & Suites Rochester – Mayo Clinic Area by IHG
Holiday Inn Express & Suites Rochester – Mayo Clinic Area by IHG
16. Hampton Inn Rochester-South
Hampton Inn Rochester-South
17. Comfort Inn & Suites West - Medical Center
Comfort Inn & Suites West - Medical Center
18. Spark by Hilton Rochester South
Spark by Hilton Rochester South
19. Hotel Indigo Rochester – Mayo Clinic Area by IHG
Hotel Indigo Rochester – Mayo Clinic Area by IHG
20. Kahler Grand Hotel
Kahler Grand HotelCompare top hotels in Rochester
![]() Hyatt House Rochester/Mayo Clinic AreaDowntown Rochester | ![]() TownePlace Suites by Marriott Rochester Mayo Clinic AreaKutzky Park | ![]() Home2 Suites by Hilton Rochester Mayo Clinic AreaRochester | ![]() Hilton Rochester Mayo Clinic AreaDowntown Rochester | ![]() Holiday Inn Express Rochester South - Mayo Area by IHGRochester |
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9.0 Wonderful 1,006 reviews | 9.6 Exceptional 577 reviews | 9.6 Exceptional 1,003 reviews | 9.6 Exceptional 657 reviews | 8.8 Excellent 1,004 reviews |
The price is NT$3,650 NT$4,202 total includes taxes & fees Nov 27 - Nov 28 | The price is NT$4,497 NT$5,177 total includes taxes & fees Nov 27 - Nov 28 | The price is NT$3,660 NT$4,213 total includes taxes & fees Nov 29 - Nov 30 | The price is NT$5,552 NT$6,392 total includes taxes & fees Nov 27 - Nov 28 | The price is NT$2,823 NT$3,250 total includes taxes & fees Nov 14 - Nov 15 |
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Where to stay in Rochester

Downtown Rochester
Downtown Rochester pulses around Mayo Clinic's towering medical complex, where glass-walled hospitals create a modern healthcare cityscape. The Plummer Building's distinctive clock tower anchors the district. Medical shuttles weave between facilities as patients navigate tree-lined streets. Peace Plaza offers respite with fountains and sculptures. This medical hub features excellent walkability with the Mayo shuttle system connecting facilities every 10-15 minutes. Silver Lake Park nearby provides scenic walking paths. Downtown dining emphasizes quick, healthy options with extended hours. Most accommodations offer patient amenities and clinic shuttles.

Kutzky Park
Kutzky Park is a charming residential haven in Rochester with tree-lined streets and early 20th-century homes. Its namesake park offers walking paths, playgrounds, and green lawns perfect for picnics. History and architecture fans will appreciate the well-preserved Craftsman and Colonial Revival homes. The quiet neighborhood provides a peaceful retreat from city life. Tennis enthusiasts can visit Kutzky Park Tennis Center for a match. While dining options are limited within the area, downtown Rochester's attractions are just a short drive away.

Historic Southwest
Historic Southwest showcases Rochester's architectural heritage with grand early 1900s homes built by Mayo Clinic physicians. Colonial Revival, Tudor, and Prairie style mansions line tree-canopied streets, creating an elegant atmosphere. The quiet neighborhood offers peaceful strolls along uncrowded sidewalks. Visitors appreciate the area's authentic residential character and meticulously maintained properties. While dining and shopping require a short trip to downtown, the neighborhood's charm lies in its historic bed & breakfasts with period furnishings. Downtown Rochester's attractions remain just minutes away by car.
East Side Pioneers
East Side Pioneers offers Rochester visitors a peaceful suburban retreat away from the downtown bustle. Tree-lined streets and single-family homes create a calm atmosphere for those seeking quiet after busy days. Parks like Mayo and Silver Lake provide natural escapes within this family-oriented area. The neighborhood serves as an affordable base for Mayo Clinic patients needing extended stays. Though dining options are limited locally, downtown Rochester's restaurants are just a short drive away. Art enthusiasts can visit the nearby Rochester Art Center and Civic Theater for a taste of local culture.

Slatterly Park
Slatterly Park neighborhood offers a peaceful retreat with tree-lined streets and charming mid-century homes. Rochester locals walk their dogs along shaded sidewalks while children play in the central park. Historic architecture tells the story of this authentic residential area away from the medical center hustle. The namesake park serves as a community hub with open green lawns, playgrounds, and walking paths. Architecture enthusiasts will appreciate the diverse styles from Craftsman bungalows to Colonial Revival homes. Downtown attractions like the Rochester Art Center and Mayo Civic Center are just a short drive away.
Stay near popular Rochester attractions
Rochester and related destinations
Home to the world-famous Mayo Clinic, this city offers surprising cultural richness with its vibrant downtown art scene and Plummer Building tours. Explore the peaceful Quarry Hill Nature Center trails in morning hours, then sample local craft beers at one of the breweries along Historic 3rd Street.

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