Central Missouri Luxury Vacations 2026

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Top Luxury Central Missouri Hotels

Ramada by Wyndham Columbia

901 Conley Rd Columbia MO

2 hours drive from Lake of the Ozarks

Ramada by Wyndham Columbia awaits for a deluxe vacation. Popular amenities include an outdoor pool and a fitness center.

voco The Tiger Hotel Columbia, MO by IHG

23 S 8th St Columbia MO

2 hours drive from Lake of the Ozarks

Pamper yourself with a luxury stay at voco The Tiger Hotel Columbia, MO by IHG, where you can enjoy amenities like 24-hour room service, pillowtop beds, and ...

9/10 Wonderful! (1,000 reviews)

"Classy, old world hotel with a rich history and solid reputation that’s simply losing its luster. Have stayed here a few times in the past and this time was the worst by far!"

Reviewed on 2026/7/21

Lodge Of Four Seasons Golf Resort, Marina & Spa

315 Four Seasons Dr. Lake Ozark MO

20 min drive from Lake of the Ozarks

Pamper yourself with a luxe vacation at Lodge Of Four Seasons Golf Resort, Marina & Spa. Popular amenities include a spa, a golf course, and 5 bars.

7.4/10 Good! (1,279 reviews)

"While paying almost 200 dollars per night, we never saw any house cleaning, had the same towels for 4 days, the toilet snapped loose every time someone sat on it. the Air conditioning was very loud and the parking was poor. The property has not been updated in years and it shows."

Reviewed on 2026/8/6

See all 5,251 properties in Central Missouri

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.