Find Luxury Hotels in West Main Historic District, KY

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Check availability on West Main Historic District Luxury Hotels

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Our top choices for West Main Historic District luxury hotels

21c Museum Hotel Louisville

21c Museum Hotel Louisville
4.5 star property
Downtown Louisville
9.2 out of 10, Wonderful, (1003)
"Staff was very kind, the art was fantastic, location was perfect to explore Whiskey Row, and we had a gorgeous room. Loved our time away there!"
United States
Tammy
The price is NT$3,627
NT$4,424 total
includes taxes & fees
Jan 2 - 2026/1/3
21c Museum Hotel Louisville

Galt House Hotel Trademark Collection by Wyndham

Galt House Hotel Trademark Collection by Wyndham
4.0 star property
Downtown Louisville
9.0 out of 10, Wonderful, (3913)
"Great place to stay! "
United States
Rochelle
The price is NT$4,190
NT$4,930 total
includes taxes & fees
Jan 5 - 2026/1/6
Galt House Hotel Trademark Collection by Wyndham

Embassy Suites Louisville Downtown

Embassy Suites Louisville Downtown
4.0 star property
Downtown Louisville
9.0 out of 10, Wonderful, (1130)
"Staff was courteous, hotel was beautiful and clean, and breakfast was amazing!"
United States
Shunskis
The price is NT$3,841
NT$4,519 total
includes taxes & fees
Jan 11 - 2026/1/12
Embassy Suites Louisville Downtown

Econo Lodge Louisville Downtown

Econo Lodge Louisville Downtown
2.0 star property
Downtown Louisville
7.2 out of 10, Good, (1005)
"Nice hotel with a great location near Whiskey Row. This is my 3rd stay at this hotel and will definitely come back again"
United States
Nicholas
The price is NT$1,977
NT$2,326 total
includes taxes & fees
Jan 12 - 2026/1/13
Econo Lodge Louisville Downtown

Seelbach Hilton Louisville Downtown

Seelbach Hilton Louisville Downtown
4.0 star property
Downtown Louisville
8.6 out of 10, Excellent, (1003)
"Excellent location and a great lobby bar with a top notch bourbon selection. "
United States
vincent
The price is NT$4,598
NT$5,410 total
includes taxes & fees
Jan 1 - 2026/1/2
Seelbach Hilton Louisville Downtown

Louisville Marriott Downtown

Louisville Marriott Downtown
4.0 star property
Downtown Louisville
9.0 out of 10, Wonderful, (1000)
"Very nice hotel. Great stay!"
United States
Brad
The price is NT$5,271
NT$6,202 total
includes taxes & fees
Jan 18 - 2026/1/19
Louisville Marriott Downtown

Hyatt Regency Louisville

Hyatt Regency Louisville
4.0 star property
Downtown Louisville
8.8 out of 10, Excellent, (1002)
"Enjoyed our stay "
United States
Jedediah
The price is NT$3,992
NT$4,697 total
includes taxes & fees
Jan 8 - 2026/1/9
Hyatt Regency Louisville

Hampton Inn Louisville Downtown

Hampton Inn Louisville Downtown
2.5 star property
Downtown Louisville
8.4 out of 10, Very Good, (1002)
"My wife and I had a wonderful time. Walking distance to many things to do. Would stay again. "
United States
Jeff
The price is NT$2,810
NT$3,306 total
includes taxes & fees
Jan 11 - 2026/1/12
Hampton Inn Louisville Downtown

Residence Inn by Marriott Louisville Downtown

Residence Inn by Marriott Louisville Downtown
3.0 star property
Downtown Louisville
8.8 out of 10, Excellent, (1000)
"Clean room, great location,walkable to everything, parking in and out no hassle, very nice staff!"
United States
Russell
The price is NT$3,175
NT$3,736 total
includes taxes & fees
Jan 3 - 2026/1/4
Residence Inn by Marriott Louisville Downtown
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top West Main Historic District Hotel Reviews

Frequently asked questions

Are you looking for a luxury hotel for your stay in West Main Historic District?
During your visit, you might want to enjoy the art and theater which West Main Historic District is known for.
What's the best luxury accommodation in West Main Historic District?
21c Museum Hotel Louisville is a luxury hotel with a full-service spa and in-room massages, and it's a popular choice for Expedia travelers looking for an elegant place to stay.
What's there to see and do in West Main Historic District?
Take in the sights and attractions that West Main Historic District offers with a visit to Frazier International History Museum, Louisville Slugger Museum, and Louisville Science Center. If you have extra time while you're in the area, you might want to see 21c Museum Hotel and Muhammad Ali Center.

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