Find Resorts & Hotels with Spas in Uptown, IL

Start date: Check-in selected.
To Date
End date: Check-out
    calendar shield illustration

    Change your mind

    Book hotels with free cancellation
    deals illustration

    Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in
    bed illustration

    Be picky

    Search almost a million properties worldwide

Check availability on Uptown Resorts & Hotels with Spas

Tonight
Sep 27 - Sep 28
Tomorrow
Sep 28 - Sep 29
Next weekend
Oct 3 - Oct 5
In two weeks
Oct 10 - Oct 12

Top Uptown Resorts & Hotels with Spas

21C Museum Hotel St Louis
Massages

21C Museum Hotel St Louis

4.5 star property
9.0 out of 10, Wonderful, (1390)
"Wonderful stay! "
The price is NT$4,610
NT$5,543 total
includes taxes & fees
Sep 29 - Sep 30
21C Museum Hotel St Louis
Four Seasons Hotel St Louis
Couples treatment rooms, hot tub, body treatments, aromatherapy

Four Seasons Hotel St Louis

5.0 star property
9.4 out of 10, Exceptional, (1002)
"Beautiful stay at the four seasons! "
The price is NT$12,972
NT$15,168 total
includes taxes & fees
Oct 4 - Oct 5
Four Seasons Hotel St Louis
The Ritz-Carlton, St. Louis
Body treatments, aromatherapy, hot stone massages, deep-tissue massages

The Ritz-Carlton, St. Louis

5.0 star property
9.2 out of 10, Wonderful, (550)
"Service is exceptional!!!"
The price is NT$17,672
NT$20,586 total
includes taxes & fees
Sep 28 - Sep 29
The Ritz-Carlton, St. Louis
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Top Uptown Hotel Reviews

Drury Plaza Hotel St. Louis at the Arch

Drury Plaza Hotel St. Louis at the Arch

10/10 Excellent
"It was a dream. East to get to the arch, beautiful property. Clean room. "
Hailey 1-night trip
Posted 16 hours ago
Drury Plaza Hotel St. Louis at the Arch

Explore a world of travel with Expedia

Explore a world of travel with Expedia

Frequently asked questions

Looking for a spa hotel in Uptown?
Treat yourself to some pampering and book a hotel with a spa. Hotels with spas are the perfect way to break away from your routine and add a layer of luxury to your weekend away.
What's there to see and do in Uptown?
When you're in Uptown, enjoy exploring the sights and attractions here including World's Largest Catsup Bottle, Gateway Arch, and Busch Stadium. If you have a little extra time during your trip, you might want to check out St. Louis Union Station and Gateway Conference Center.
What is a Uptown spa hotel?
Spa hotels in Uptown have on-site spas and offer services including therapies and a choice of body treatments. Some also provide a selection of in-room treatments for the ultimate luxury. Spa hotels are great for rest, rejuvenation, and relaxation.