Southwest Illinois Vacations

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Photo by Southernmost Illinois Tourism Bureau

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Where to stay in Southwest Illinois

Find the best Southwest Illinois areas and neighborhoods for the activities you enjoy most. Learn more about Southwest Illinois
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Eastport

If you're spending some time in Eastport, Gateway Conference Center and Splash City Family Waterpark are top sights worth seeing.

Find hotels in Eastport

Find the Best Southwest Illinois Vacation Packages

Southwest Illinois Hotel Deals

Drury Plaza Hotel Mt. Vernon

Drury Plaza Hotel Mt. Vernon

3 out of 5
145 North 44th Street , Mount Vernon, IL
Fully refundableReserve now, pay when you stay
The price is NT$2,855 per night from Oct 19 to Oct 20
NT$2,855
NT$3,229 total
Oct 19 - Oct 20
includes taxes & fees
9.6/10 Exceptional! (1,479 reviews)
"I liked the evening drinks and dinner"

Reviewed on 2025/9/30

Drury Plaza Hotel Mt. Vernon
Super 8 by Wyndham O'Fallon

Super 8 by Wyndham O'Fallon

2 out of 5
1100 Eastgate Dr, O'Fallon, IL
Fully refundableReserve now, pay when you stay
The price is NT$1,549 per night from Oct 12 to Oct 13
NT$1,549
NT$1,781 total
Oct 12 - Oct 13
includes taxes & fees
7.2/10 Good! (1,000 reviews)
"Nice room"

Reviewed on 2025/9/30

Super 8 by Wyndham O'Fallon
Quality Inn & Suites near St. Louis and I-255

Quality Inn & Suites near St. Louis and I-255

2.5 out of 5
1607 Pontiac Dr, East St. Louis, IL
Fully refundableReserve now, pay when you stay
The price is NT$2,183 per night from Oct 12 to Oct 13
NT$2,183
NT$2,467 total
Oct 12 - Oct 13
includes taxes & fees
7.4/10 Good! (1,013 reviews)
"Great hotel for the price"

Reviewed on 2025/9/21

Quality Inn & Suites near St. Louis and I-255
See all 714 properties in Southwest Illinois
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Discover the most popular places to visit in Southwest Illinois

Campus Lake at Southern Illinois University in Carbondale, IL.

Southern Illinois University

4.5/5(173 reviews)

Take a campus tour or just explore the area of Southern Illinois University, during your trip to Carbondale. Check out the shops and top-notch restaurants in this family-friendly area.

Southern Illinois University

World Wide Technology Raceway

Catch an event at World Wide Technology Raceway during your trip to St. Louis. Attend a sporting event or simply enjoy the top-notch restaurants while you're in the area.

World Wide Technology Raceway

Gateway Conference Center

4.5/5(2 reviews)

Gateway Conference Center is just one of the places to see in Collinsville, so why not enjoy the other things to explore during your travels? Discover the top-notch restaurants and great live music in this walkable area.

Gateway Conference Center

Frequently asked questions

Can I cancel my flight booking to Southwest Illinois due to COVID-19?
If you haven't booked yet, glance over the terms and conditions of the airfare you're considering. If you've already reserved your flight to Southwest Illinois, visit our Customer Service Portal. It will help you figure out which COVID-19 policies are applicable to your reservation and offer advice on the next steps.
What's the best way to find cheap flights to Southwest Illinois that have flexible change policies?
When it comes to flying these days, flexibility is crucial. That's why we have a "No change fee" search function to help you track down flexible, affordable flights to Southwest Illinois. It's at the top left of your screen directly below the "Flexible change policies" subheading.
What are some of the general tips for travelers to Southwest Illinois during the COVID-19 outbreak?
The COVID-19 pandemic has affected how the world works in a profound way, including our approach to travel. These tips will help you understand these new challenges and prepare you for your vacation in Southwest Illinois:
  • Research what, if any, restrictions or rules apply to both your origin and destination. It may not be possible to travel depending on local circumstances, so don't forget to check in advance.
  • When you go through airport screening, keep your face mask on. You will be required to lower it briefly for ID purposes. Anyone refusing to wear a face mask may face civil penalties and may also be denied boarding.
  • To reduce the likelihood of cross-contamination, position your boarding pass on the reader yourself and then hold it up for inspection. Do not hand your boarding pass directly to a TSA agent.
  • One liquid hand sanitizer container is now allowed in your carry-on luggage. It must be no larger than 12 oz (350 ml), and you'll need to remove it from your bag at the X-ray machine for scanning.
  • To minimize handling during the screening process, put items such as your phone, keys and wallet into your carry-on instead of the bins.
  • Separate any food you have for X-ray scanning. Food items often set off the alarm. Placing them in a clear plastic bag and into a bin reduces the need for a TSA officer to handle and inspect your belongings.

Which airlines fly to Southwest Illinois?
Organize your fare with Delta and then start planning your Southwest Illinois travel itinerary. This top airline provides 121 flights each month to Evansville Regional Airport (EVV), a main gateway.
How can I find cheap tickets to Southwest Illinois?
A useful strategy for getting your hands on cheap fares is to be flexible with your dates. Begin with searching for your flight to Southwest Illinois, then click on the "flexible dates" link for a list of prices for nearby days. Another helpful hint? Book ahead of time. For an idea of costs, was the lowest price for a flight to Southwest Illinois in the last seven days.
How much is a flight to Southwest Illinois?
If you were jetting one way from (), you could've snapped up a cheap seat for just in the last seven days. Return flights to Southwest Illinois ranged from only to over the same period.
What are the most popular airports to fly into in Southwest Illinois?
Southwest Illinois's main entryway is Evansville Regional Airport (EVV). Get your awesome journey underway by securing an airfare on one of the 381 flights every month to this destination.
When is the cheapest time to fly to Southwest Illinois?
If you'd rather spend your vacation money enjoying Southwest Illinois rather than on getting there, depart early in the week. The most economical day to fly is usually Tuesday, followed by Monday. With many people traveling on weekends, Saturday typically has the most expensive fares.
How much is a plane ticket to Southwest Illinois?
Seats ranged from to over the last seven days. When you're ready to book, we're here to help lock in a fabulous deal to Southwest Illinois.
Which airlines with flights to Southwest Illinois employ COVID-19 cleanliness policies?
In response to the COVID-19 pandemic, airlines have adopted enhanced measures and standards to help their passengers and staff fly with peace of mind. Here are just a few examples:
  • Southwest Airlines - this airline is known for providing passenger masks and cleaning with disinfectant.
  • American Airlines - this airline is known for providing passenger masks and cleaning with disinfectant.
  • Delta - this airline is known for electrostatic cleaning and cleaning with disinfectant.

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.