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Find Business Hotels in Southwest Illinois, IL
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Check availability on Southwest Illinois Business Hotels
Our top choices for Southwest Illinois business-friendly hotels

9.2 out of 10, Wonderful, (1503)
The price is NT$3,400
NT$4,003 total
includes taxes & fees
Dec 22 - Dec 23

SureStay Hotel by Best Western Whittington Rend Lake
SureStay Hotel by Best Western Whittington Rend LakeWhittington
8.8 out of 10, Excellent, (904)
The price is NT$2,141
NT$2,376 total
includes taxes & fees
Dec 31 - 2026/1/1

7.8 out of 10, Good, (1006)
The price is NT$2,100
NT$2,394 total
includes taxes & fees
Jan 4 - 2026/1/5

8.2 out of 10, Very Good, (1006)
The price is NT$2,221
NT$2,665 total
includes taxes & fees
Jan 18 - 2026/1/19

Holiday Inn Express & Suites Murphysboro - Carbondale by IHG
Holiday Inn Express & Suites Murphysboro - Carbondale by IHGMurphysboro
9.4 out of 10, Exceptional, (512)
The price is NT$3,185
NT$3,535 total
includes taxes & fees
Dec 20 - Dec 21

8.8 out of 10, Excellent, (3031)
The price is NT$2,836
NT$3,310 total
includes taxes & fees
Dec 21 - Dec 22

9.0 out of 10, Wonderful, (1001)
The price is NT$3,433
NT$3,873 total
includes taxes & fees
Dec 23 - Dec 24

7.2 out of 10, Good, (1000)
The price is NT$1,339
NT$1,539 total
includes taxes & fees
Dec 28 - Dec 29
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Top Southwest Illinois Hotel Reviews

Drury Plaza Hotel Mt. Vernon
10/10 Excellent
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