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Find Casinos in Southeast Missouri, MO
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Top Southeast Missouri Casinos
The Farmstead Hotel
Caruthersville
8.8 out of 10, Excellent, (460)
"Clean rooms and really comfortable beds!"
Andrea
The price is NT$2,671
NT$3,038 total
includes taxes & fees
Dec 9 - Dec 10
The Riverview
Cape Girardeau
9.4 out of 10, Exceptional, (464)
"Place was nice and safe"
ryan
The price is NT$3,008
NT$3,394 total
includes taxes & fees
Dec 8 - Dec 9
Courtyard by Marriott Cape Girardeau Downtown
Cape Girardeau
9.6 out of 10, Exceptional, (466)
"The staff was very helpful and friendly. The rooms were modern and clean. The downtown location was perfect for us. "
Deborah
The price is NT$3,624
NT$4,106 total
includes taxes & fees
Dec 21 - Dec 22
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
Jackson
8.8 out of 10, Excellent, (660)
"Great place "
GUY
The price is NT$2,443
NT$2,644 total
includes taxes & fees
Jan 4 - 2026/1/5
Baymont by Wyndham Festus
Festus
6.8 out of 10, (918)
"Room was clean and comfortable for an overnight stay"
Jack
The price is NT$2,530
NT$2,893 total
includes taxes & fees
Dec 9 - Dec 10
Rockwood Inn
Cape Girardeau
10.0 out of 10, Exceptional, (18)
"We came into town for a concert and had a blast! The hotel was super comfy, and the staff were friendly. The rooms were very clean and the decor was beautiful! "
Vanessa
The price is NT$4,695
NT$5,296 total
includes taxes & fees
Dec 14 - Dec 15
Century Casino & Hotel Caruthersville
Caruthersville
8.6 out of 10, Excellent, (103)
"Room was clean staff was really nice"
Toni
The price is NT$3,796
NT$4,317 total
includes taxes & fees
Dec 8 - Dec 9
River City Casino & Hotel
St. Louis
9.0 out of 10, Wonderful, (1447)
"Awesome place to stay!!"
Kaitlyn
The price is NT$2,749
NT$3,653 total
includes taxes & fees
Dec 8 - Dec 9
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Top Southeast Missouri Hotel Reviews
Pear Tree Inn Cape Girardeau Near the Medical Center
10/10 Excellent
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Hotels near popular Southeast Missouri Attractions
- Hotels near Mark Twain National Forest
- Hotels near Southeast Missouri State University
- Hotels near Johnson's Shut-ins State Park
- Hotels near Elephant Rocks State Park
- Hotels near Ozark National Scenic Riverways
- Hotels near Century Casino Caruthersville
- Hotels near Current River
- Hotels near Isle Casino Cape Girardeau
- Hotels near Lake Wappapello
- Hotels near Echo Bluff State Park
Southeast Missouri Hotels by Star Rating
Explore more hotels
- Courtyard by Marriott Cape Girardeau Downtown
- Drury Inn & Suites Sikeston, MO
- Drury Inn & Suites Jackson MO
- Pear Tree Inn Cape Girardeau Near the Medical Center
- Pear Tree Inn Cape Girardeau West
- Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
- Candlewood Suites Cape Girardeau by IHG
- Drury Inn & Suites Poplar Bluff
- Baymont by Wyndham Festus
- Hampton Inn Poplar Bluff
- Drury Inn & Suites Cape Girardeau
- Super 8 by Wyndham Farmington
- Hampton Inn Cape Girardeau I 55 East
- Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)
- Holiday Inn Express Hotel & Suites FESTUS - SOUTH ST. LOUIS by IHG
- Best Western Plus Sikeston
- Econo Lodge
- Holiday Inn Express & Suites Perryville by IHG
- Quality Inn
- Drury Inn & Suites Hayti Caruthersville
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