Top 10 Hotels in Southeast Missouri, MO from NT$1,987 - Competitive Prices

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Go beyond your typical stay in Southeast Missouri

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Our top choices for Southeast Missouri hotels

A kitchen with wooden cabinets, a stainless steel refrigerator, a microwave, a stove, and a granite countertop.

A compact kitchen with wooden cabinets, a stainless steel refrigerator, and a microwave.

A building with a red awning labeled "Shepherd Mountain Inn."

A hotel room with two beds, a lamp, and a painting on the wall.

1. Shepherd Mountain Inn

Ironton

Michael

NT$3,938

NT$4,302 total

includes taxes & fees

Oct 12 - Oct 13

A motel with a covered entrance, a flag, and a phone number.

A hotel room with two beds, a desk, a chair, a TV, and a bathroom.

A reception desk with a wooden finish, a framed black and white cityscape, and a large framed Eiffel Tower picture.

A living room with a black leather sofa, a wooden coffee table with a vase of flowers, a green potted plant, and a lamp.

2. Madison Inn Lodge

Fredericktown

Bawan

NT$2,587

NT$2,825 total

includes taxes & fees

Nov 3 - Nov 4

A hotel room with a bed, bedside tables, a desk, a chair, a lamp, and a window.

3. Hampton Inn & Suites By Hilton Festus

Festus

NT$2,855

NT$3,264 total

includes taxes & fees

Oct 18 - Oct 19

A hotel room with a large bed, a nightstand, a lamp, a chair, and a mirror.

A buffet with various food items, including omelets and other dishes, served in metal containers with glass lids.

A hotel lobby with a seating area, a reception desk, and a bar.

A swimming pool with a diving board, pool rules signs, and lounge chairs.

4. Holiday Inn Express & Suites Perryville by IHG

Perryville

Lisa

NT$3,034

NT$3,473 total

includes taxes & fees

Nov 8 - Nov 9

A modern lounge area with a stone fireplace, blue seating, a round coffee table, and a large window offering a view.

A reception area with a wooden counter, a coffee machine, and a display of pastries.

An outdoor patio with a table and chairs, a large umbrella, and a glass door leading to an interior space.

A corner market with a refrigerated display case and a pantry area.

5. Fairfield Inn & Suites by Marriott Poplar Bluff

Poplar Bluff

Nancy

NT$3,095

NT$3,496 total

includes taxes & fees

Oct 18 - Oct 19

A spacious lobby with a large sectional sofa, multiple armchairs, and a coffee table. There is a TV mounted on the wall and a large window providing a view of the outdoors.

A restaurant with a brick wall, a flat-screen TV, and a bar area.

An indoor swimming pool with a wooden ceiling, lounge chairs, and a lifeguard chair.

A Drury Inn & Suites building with a traditional architectural style, featuring a covered entrance and multiple windows.

6. Drury Inn & Suites Jackson MO

Jackson

Debra S

NT$2,550

NT$2,696 total

includes taxes & fees

Oct 13 - Oct 14

An indoor swimming pool with a brick border, wooden walls, and a view of the outdoors.

A spacious hotel lobby with a dining area, kitchen, and large windows.

A hotel room with two beds, a desk, a chair, a TV, and a window with curtains.

A lobby with a stone fireplace, two sofas, a coffee table, and two lamps.

7. Crown Pointe Lodge, BW Signature Collection

Farmington

CURTIS

NT$3,496

NT$3,998 total

includes taxes & fees

Nov 4 - Nov 5

A modern living room with a sofa, armchairs, a coffee table, and a TV mounted on the wall.

A reception area with a wooden reception desk, a glass door leading to a storage room, and a decorative wall piece.

A modern living room with a sofa, a coffee table, and a dining area with chairs and a table.

A Fairfield by Marriott hotel with a modern design, featuring a stone facade, multiple floors, and a well-lit entrance.

8. Fairfield Inn & Suites by Marriott Cape Girardeau

Cape Girardeau

Carlos

NT$3,225

NT$3,638 total

includes taxes & fees

Oct 15 - Oct 16

A modern kitchen with a coffee machine, a refrigerator, and a microwave.

A laundry room with a front-loading washer and dryer, a door, and a light fixture.

A long, narrow hallway with patterned carpet, doors on both sides, and a ceiling light.

A hotel lobby with a reception desk, a blue armchair, a wall-mounted clock, and a framed welcome sign.

9. Super 8 by Wyndham Farmington

Farmington

Marisa

NT$1,897

NT$2,169 total

includes taxes & fees

Oct 15 - Oct 16

A spacious dining area with multiple tables and chairs, a flat-screen TV mounted on the wall, and large windows providing natural light.

10. Hampton Inn Poplar Bluff

Poplar Bluff

NT$2,905

NT$3,253 total

includes taxes & fees

Oct 18 - Oct 19

A modern lobby with seating areas, a patterned carpet, and a cityscape mural on the wall.

A swimming pool with lounge chairs and a view of the night sky.

A spacious lobby with a modern design, featuring a large seating area with purple and gray chairs, a patterned carpet, and a cityscape mural on the wall.

A modern hotel with a prominent 'La Quinta' sign, large windows, and a well-lit entrance.

11. La Quinta Inn & Suites by Wyndham Festus - St. Louis South

Festus

Debra S

NT$2,688

NT$3,073 total

includes taxes & fees

Oct 12 - Oct 13

A living room with a blue wall, a fireplace, a sofa, and a chair.

A sign for EC REED'S MERCANTILE & HOTEL with a geometric design.

A brick building with a sign reading "Mercantile & Hotel".

A bar area with stools and a counter where a bartender is serving drinks.

12. EC Reed's Mercantile and Hotel

Marble Hill

JANEEN

NT$3,352

NT$3,649 total

includes taxes & fees

Nov 1 - Nov 2

A spacious lobby with a circular seating area, a stone fireplace, and modern lighting fixtures.

A Drury Plaza Hotel with a modern design, featuring a prominent entrance, multiple floors, and a clear sky.

A spacious lobby with a curved seating area, a reception desk, and a large window providing natural light.

An indoor swimming pool with clear blue water, surrounded by beige walls and large windows.

13. Drury Plaza Hotel Cape Girardeau Conference Center

Cape Girardeau

Curtis

NT$3,188

NT$3,597 total

includes taxes & fees

Oct 13 - Oct 14

A modern kitchen with a central island, built-in appliances, and a view into the dining area.

A reception desk with a modern design, a digital screen, and a sign indicating 'IHG' branding.

A swimming pool area with a clear pool, a lifeguard chair, and a sign indicating the pool's depth.

A modern hotel with a stone facade, multiple windows, outdoor seating, and a visible sign for the Holiday Inn Express & Suites.

14. Holiday Inn Express Hotel & Suites FESTUS - SOUTH ST. LOUIS by IHG

Festus

Denise

NT$3,189

NT$3,646 total

includes taxes & fees

Oct 25 - Oct 26

A hotel room with two beds, a desk, a chair, a TV, and a lamp.

A hotel room with a television, a desk, a chair, a dresser, a radiator, and a bathroom visible through an open door.

A reception desk with a woman standing behind it, a man with a suitcase, and another person standing to the left.

A two-story building with a green roof and a large circular sign that reads "Port David Restaurant".

15. Fort Davidson Hotel

Ironton

richard

NT$3,986

NT$4,354 total

includes taxes & fees

Oct 12 - Oct 13

A spacious lobby with a reception desk, seating area, and large windows.

A hotel room with a bed, a desk, a chair, a sofa, and a TV.

A spacious conference room with brick walls, multiple tables and chairs, a large window, and a mounted TV.

A spacious lobby with a high ceiling, a mezzanine level, and a seating area with a sofa and chairs.

16. Drury Inn & Suites Poplar Bluff

Poplar Bluff

NT$3,002

NT$3,391 total

includes taxes & fees

Oct 18 - Oct 19

A shower area with a white curtain, a handheld showerhead, and a grab bar.

A parking lot with a tree in bloom, a red fire hydrant, and a building in the background.

A hotel reception area with a glass partition, a reception desk, and a digital kiosk.

A hotel room with a large bed, two sofas, a desk with a lamp, a microwave, and a TV.

17. Baymont Inn and Suites by Wyndham Farmington, MO

Farmington

stewart

NT$1,737

NT$1,987 total

includes taxes & fees

Nov 1 - Nov 2

An outdoor seating area with a circular fire pit surrounded by chairs, a covered patio, and a building with large windows in the background.

A modern hotel building with a sign reading "TOWNPLACE SUITES BY MARRIOTT" and "Fairfield BY MARRIOTT".

An outdoor bar area with a modern design, featuring a counter, seating, and a view of the interior.

A modern indoor swimming pool with clear glass walls, a tiled deck, and multiple lounge chairs.

18. Fairfield Inn & Suites by Marriott Sikeston

Sikeston

Allen

NT$3,220

NT$3,662 total

includes taxes & fees

Oct 15 - Oct 16

A hotel room with a large bathtub, a sofa, a small table, a TV, and a window with curtains.

A hotel room with a kitchenette, a large mirror, a sofa, and a patterned carpet.

A hotel room with a large bed, a desk with a chair, a television, and a small table with a lamp.

A spacious lobby with a checkered floor, two sofas with patterned cushions, a computer desk, and a reception area with a glass door.

19. Super 8 by Wyndham Perryville

Perryville

Matthew

NT$2,172

NT$2,486 total

includes taxes & fees

Nov 8 - Nov 9

A spacious lobby with a curved staircase, large windows, and a seating area with a rug.

A modern living room with a large sectional sofa, a flat-screen TV, and a view of the sea through large windows.

A modern bar area with a herringbone patterned wall, a long counter with bar stools, and a variety of bottles and glasses.

A hotel room with two beds, a desk, a chair, and a view of the city.

20. The Riverview

Cape Girardeau

NT$3,644

NT$4,111 total

includes taxes & fees

Oct 13 - Oct 14

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Vacation Rentals in Southeast Missouri

Aparthotel

A rustic interior with exposed brick walls, wooden railings, and a hanging floral chandelier.

A building with a sign that reads "The Atrium Boutique Hotel".

A building with a dark exterior, a large window, and a sign that reads "The Atrium."

A fireplace with a decorative mantel, a framed sign, and a small table with plants.

The Atrium - A Boutique Hotel

Perryville

"What an amazing little suite wrapped in a very thought-filled overall venue. Very unique room with a so many details. The overall building with fire pit, game rooms, and local vendor items…all was quite amazing. Every element is thought out very well. It is very convenient and overall comfortable. It was a great getaway."

Cabin

A bedroom with a bed, a wooden headboard, a window with a view of greenery, and a tray with breakfast items.

A cabin with two Adirondack chairs outside, a picnic table, and a small black structure with a window and a sign.

Postcard Cabins St Francois, Outdoor Collection by Marriott Bonvoy

French Village

Cottage

A dining area with a checkered tablecloth, wooden chairs, and a red rug.

A swimming pool with a wooden deck, surrounded by a white picket fence, and featuring colorful umbrellas.

An outdoor patio with a table and chairs, a grill, and a large umbrella.

A two-story house with a red exterior, a front porch, and a well-maintained lawn.

'turtle Rock' - Ironton Cabin w/ Furnished Patio!

Ironton

"Stroller, pack n play and high chair. This was amazing "

Aparthotel

A modern kitchen with a large island, stainless steel appliances, and exposed brick walls.

A bedroom with a bed, a bench, a ceiling fan, a mirror, and a wooden floor.

A hallway with exposed brick walls, wooden flooring, and a white door.

A large building with multiple green-roofed structures, surrounded by well-maintained lawns and a parking area.

Urban Lofts

Perryville

"Beautiful place and staff was amazing!"

Vacation Home

A wooden deck with two Adirondack chairs and a hammock.

A bedroom with a large bed, wooden ceiling, and a view of the outdoors.

A spacious living room with a wooden ceiling, a fireplace, and a television.

A spacious living room with wooden floors, a stone fireplace, and a mounted television.

Tiny Houses of French Village

French Village

"Very nice place very clean well kept inside an out it's a nice little romantic getaway they have it set up so great its a must see sunset very relaxing "

Cabin

A calm lake with a wooden dock and a forested island in the distance.

A wooden deck with a railing leading to a building with a metal roof and a brown door.

A bedroom with a wooden bed, a bench, and a window.

Lake Wappapello

Williamsville

"Pet friendly. Family-friendly "

Cottage

A bedroom with a large bed, a sofa, a wooden wardrobe, and a ceiling fan.

A single-story house with a front porch, a stone foundation, and a well-maintained lawn.

A covered porch with yellow chairs, a bench, and a small table.

A spacious living area with a kitchen island, dining table, and a television.

Walk to Dtwn: Ironton Home in Historic District

Ironton

"Clean and comfortable "

Cottage

A cozy cabin interior with a wooden interior, a fireplace, a television, and a comfortable seating area.

A wooden deck leading to a house with a wooden door and a small porch area.

Walk to Current River: Ozarks Adventure Home!

Van Buren

"Teresa & Chuck went out of their way to make the stay EXCELENT. Teresa is a great cook and shared some of her creations with me, again EXCELENT. The lodging was comfortable and easy to access. Next time in town that will be the place for me."

Cottage

A spacious living room with a high wooden ceiling, two sofas, a coffee table, a TV, and a bookshelf.

A red house with a wooden deck, large sliding glass doors, and a chimney.

A bedroom with a bed, two bedside tables, a dresser, a ceiling fan, and a window with curtains.

A red house with a wooden deck and stone steps leading to a porch.

Cozy Belgrade Cottage w/ Wood-burning Stove!

Belgrade

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Stay near popular Southeast Missouri attractions

A large, reddish-brown rock formation with a smooth, rounded surface and a unique, intertwined shape.

Elephant Rocks State Park

9.6/10 (98 reviews)

You can take time to visit Elephant Rocks State Park during your travels to Ironton. While you're in the area, wander around the parks.

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A large, historic building with a dome and columns, surrounded by well-maintained lawns and trees.

Southeast Missouri State University

8.8/10 (248 reviews)

Take a campus tour or just explore the area of Southeast Missouri State University, during your trip to Cape Girardeau. While in this family-friendly area, you can savor the top-notch restaurants.

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A sunset over a lake with boats and ducks.

Lake Wappapello

8.8/10 (54 reviews)

Commune with nature and explore the great outdoors at Lake Wappapello during your travels in Wappapello. While in this family-friendly area, you can enjoy the restaurants.

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Century Casino & Hotel Cape Girardeau

8.4/10 (176 reviews)

Why not roll the dice with a visit to Century Casino & Hotel Cape Girardeau during your travels in Cape Girardeau? While in this family-friendly area, you can savor the top-notch restaurants.

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Century Casino Caruthersville

7.0/10 (57 reviews)

Why not roll the dice with a visit to Century Casino Caruthersville during your travels in Caruthersville? While in this family-friendly area, you can enjoy the restaurants.

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Learn more about Southeast Missouri

Explore the family-friendly area of Southeast Missouri—restaurants, wineries, and sights from K Bridge Recreation Area to Lake Wappapello State Park.

See all hotels in Southeast Missouri

A historical marker sign for the Frisco Depot, detailing its construction in 1928, architectural style, and historical significance.

Top Southeast Missouri Hotel Reviews

Days Inn and Suites by Wyndham Sikeston

8/10 Good

"We were traveling through and wanted a quiet clean place to sleep. This was quiet clean although it is a bit dated. Only issue with maintenance was the outlet in the bathroom did not work which did not bother us but it should be attended to. We actually had a suite so it was very spacious. It was about $30 less than other rooms that were available in the area so it was quite a value in my opinion."

Drury Inn & Suites Cape Girardeau

10/10 Excellent

"The whole experience here during our stay was wonderful. Staff was friendly, everything was clean and well maintained. We would definitely stay here again."

Drury Inn & Suites Hayti Caruthersville

8/10 Good

"Great place, little expensive!"

Hampton Inn Poplar Bluff

8/10 Good

"Staff very helpful"

Hampton Inn Sikeston

10/10 Excellent

"Loved the modern, CLEAN, room and staff was extremely friendly and helpful. We were greeted and served by "Brittany" at check-in who was so nice and friendly and even gave us dinner suggestions. We would definitely stay here again!"

Drury Inn & Suites Sikeston, MO

10/10 Excellent

"Everything was up to par, good was excellent."

Baymont Inn and Suites by Wyndham Farmington, MO

8/10 Good

"Great value. Great location. My place to stay in the Farmington area."

Postcard Cabins St Francois, Outdoor Collection by Marriott Bonvoy

10/10 Excellent

"Peaceful getaway. Pet friendly. Safe area"

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

10/10 Excellent

"Nice property"

More cheap stays in Southeast Missouri

Baymont Inn and Suites by Wyndham Farmington, MO

1625 W Columbia St Farmington MO

NT$1,737

NT$1,987 total

Nov 1 - Nov 2

includes taxes & fees

8/10 Very Good! (1,007 reviews)

Days Inn and Suites by Wyndham Sikeston

220 S Interstate Dr Sikeston MO

NT$2,114

NT$2,410 total

Oct 12 - Oct 13

includes taxes & fees

7.2/10 Good! (1,001 reviews)

Motel 6 Poplar Bluff, MO

4101 Highway 67 N Poplar Bluff MO

NT$2,271

NT$2,543 total

Oct 22 - Oct 23

includes taxes & fees

8/10 Very Good! (1,000 reviews)

Pear Tree Inn Cape Girardeau West

103 Cape West Pkwy Cape Girardeau MO

NT$2,295

NT$2,590 total

Oct 18 - Oct 19

includes taxes & fees

Comfort Inn Festus - St Louis South

1303 Veterans Blvd Festus MO

NT$2,274

NT$2,657 total

Nov 1 - Nov 2

includes taxes & fees

Hampton Inn Poplar Bluff

2420 Crestwood Dr Poplar Bluff MO

NT$2,905

NT$3,253 total

Oct 18 - Oct 19

includes taxes & fees

9.4/10 Exceptional! (975 reviews)

Hotels in Southeast Missouri with star-rating

Find out more about Southeast Missouri

Top reasons to visit Southeast Missouri

Outdoor Adventures: Southeast Missouri is perfect for outdoor enthusiasts, featuring scenic parks and recreational activities that invite exploration.
Cultural Experiences: Engage with local culture through campus tours, breweries, and historic civic buildings that reflect the region’s heritage.
Charming Neighborhoods: Stroll through friendly neighborhoods that offer a welcoming atmosphere and a taste of local life.
Family-Friendly Activities: The area provides a variety of activities suitable for families, making it an ideal vacation spot.
Warm Hospitality: Enjoy the warmth of Southern hospitality in a range of charming hotels and lodges.

Find great hotels near Southeast Missouri

Discover a range of charming hotels in Southeast Missouri, perfect for business travelers, adventure seekers, and couples looking for a romantic getaway. Whether you’re searching for the closest accommodations or the best-reviewed options, you’ll find a variety of lodges and hotels that cater to your needs. Embrace the warmth of Southern hospitality and make your stay in Southeast Missouri a memorable one.

Madison Inn Lodge: A welcoming motel ideal for business travelers and pet owners alike, Madison Inn Lodge is located 25.7km from Southeast Missouri. This property offers a practical and comfortable stay with amenities tailored for those traveling with pets. Guests appreciate the pet-friendly policy, which includes restrictions to ensure a pleasant environment for all. The lodge features essential amenities designed for business needs, making it a great choice for corporate travelers seeking convenience and comfort.
Shepherd Mountain Inn: Positioned 33.8km from Southeast Missouri, Shepherd Mountain Inn stands as a solid choice for business travelers. This hotel combines a professional atmosphere with essential amenities, ensuring a smooth and productive stay. Guests often note the hotel's commitment to providing a comfortable environment, making it suitable for those on work trips or visiting the area for business events. Its strategic location also allows easy access to local attractions, enhancing the overall experience.
Alpaca Farm Stay: Located 12.9km from Southeast Missouri, Alpaca Farm Stay offers a unique and adventurous escape for families and couples. This lodge invites guests to immerse themselves in a delightful rural setting, featuring adventure sports options like kayaking, mountain climbing, and fishing nearby. Families will enjoy the shared playground for children, while couples can take advantage of romantic packages. With stunning lake and mountain views available, this property ensures a memorable getaway filled with excitement and relaxation.

Where to stay near Southeast Missouri

In Southeast Missouri, visitors can enjoy a blend of outdoor adventures and picturesque scenery perfect for families. Enjoy leisurely strolls through charming neighborhoods, where friendly locals create a welcoming atmosphere. This region is known for its scenic retreats and recreational activities, making it an ideal vacation spot. With convenient locations and vibrant community vibes, Southeast Missouri promises a delightful experience for all travelers looking to unwind and explore.

Central Fredericktown: Nestled about 16.1km from Southeast Missouri, Central Fredericktown is a charming village that attracts visitors year-round, with peak seasons occurring from June to August. This quaint area is ideal for families seeking outdoor adventures and city-themed experiences. Notable activities include exploring the local recreational areas, shopping at the mall center, and visiting the history museum. The village is home to lovely parks and urban greenspaces, providing ample opportunities for relaxation and enjoyment. Central Fredericktown offers a delightful mix of history and recreation that makes it a perfect stop for tourists.
Annapolis: Located approximately 22.5km away from Southeast Missouri, Annapolis is a vibrant city known for its stunning scenery and adventurous spirit. The city sees a steady stream of visitors throughout the year, peaking in June, July, and September. Travelers flock to Annapolis for its outdoor activities and picturesque landscapes, including national state parks and rivers. With recreational areas and an arena entertainment facility, there’s no shortage of fun and excitement. Whether you’re hiking through scenic trails or enjoying a day by the water, Annapolis promises an unforgettable experience for all types of adventurers.
Des Arc: Situated around 17.7km from Southeast Missouri, Des Arc is a lively city that experiences seasonal fluctuations in visitor numbers, with the summer months from June to August being the most popular. Known for its outdoor activities and natural beauty, Des Arc is a haven for adventure seekers. Visitors can enjoy recreational areas, a water park, and an arena entertainment facility. The nearby national state park, lake, and river provide the perfect backdrop for a day of exploration and relaxation. Des Arc is an excellent destination for those looking to immerse themselves in nature while enjoying a variety of fun-filled activities.

Things to do near Southeast Missouri

Southeast Missouri offers a wealth of outdoor adventures and scenic beauty, perfect for a memorable vacation. Engage in campus tours, outdoor activities, and sports tournaments, or explore local breweries on guided tours. Educational experiences abound, making it an excellent destination for those seeking both fun and learning. With recreational areas and entertainment facilities, there's something for everyone to enjoy in this vibrant region.

Shopping

For a unique shopping experience, visit Red's Flea Market, located 41.8km from Southeast Missouri, offering a variety of local goods. For a more traditional mall experience, check out the Farmington Mineral Area Shopping Center, 48.3km away, featuring entertainment and family-friendly shops.

Recreation

Crane Lake Recreation Area offers a serene environment perfect for relaxation and wellness activities, surrounded by nature's beauty. Silver Mine Recreation Area provides a tranquil setting for rejuvenation, while Arcadia Valley Golf Club combines outdoor sports with stunning landscapes, making it ideal for both leisure and recreation.

Adventure

At Shepherd Mountain Bike Park and Hiking Trails, located 33.8km from Southeast Missouri, enjoy exhilarating mountain biking and scenic hiking. The trails offer a thrilling adventure amidst picturesque landscapes, perfect for outdoor enthusiasts seeking both excitement and natural beauty.

Nightlife

In Southeast Missouri, Cape Girardeau's Riverfront offers vibrant bars and live music, while Sikeston's popular casinos provide exciting gaming and entertainment options. Enjoy the lively atmosphere, delicious local cuisine, and friendly crowds at these nightlife hotspots, perfect for an unforgettable evening out.

*Distances are measured in a straight line; actual driving distances may vary depending on the route.

Booking tips and Expedia advantages for Southeast Missouri

To save money on your trip to Southeast Missouri, consider visiting between November and January when accommodation prices are lower. Tuesdays are the cheapest days to stay, while Saturdays are the most expensive. Use Expedia to find hotel deals by filtering options to suit your budget and preferences, including eco-certified hotels. Additionally, booking a package that combines flights and hotel stays can yield significant savings. Make sure to compare room rates to secure the best deal available for your accommodation.

The most and least expensive months on average to stay in a hotel: The cheapest months to stay around Southeast Missouri are November to January, where the prices are slightly lower. This is in comparison to April, June and August, where prices are slightly higher.
The most and least expensive days on average to stay in a hotel: The least expensive day to stay around Southeast Missouri is Tuesday. The most expensive day to stay around Southeast Missouri is Saturday.
Find cheap hotels on Expedia: Utilize Expedia’s search tool to refine your preferences, such as your budget, desired location, and preferred type of accommodation. For instance, selecting the Eco-certified option will showcase sustainable and environmentally friendly hotels that are currently available. If you're looking for the best prices and deals, simply arrange the price filter from lowest to highest.
Consider bundling your trip: You can save money by booking an Expedia package that combines your hotel accommodations in Southeast Missouri with your flights and activities.

Find the best attractions near Southeast Missouri

Southeast Missouri offers a fantastic getaway for outdoor enthusiasts and culture seekers alike. Visitors can explore scenic urban parks, national state parks, and historic civic government buildings. The area is perfect for those looking to connect with nature and experience local culture. Additionally, travelers can check out nearby attractions and visit Southeast Missouri State University for a taste of local education and community life.

Walnut Hollow Lake: Experience the serene beauty of Walnut Hollow Lake, located 20.9km from Southeast Missouri. This picturesque lake offers a charming beach, perfect for romantic getaways or family outings amidst stunning scenery.
K Bridge Recreation Area: Just 27.4km away, K Bridge Recreation Area is an urban park that caters to families and city dwellers alike. Enjoy outdoor activities surrounded by lush landscapes, making it an ideal spot for a fun-filled day with loved ones.
Millstream Gardens Conservation Area: Situated 24.1km from the city, this reserve offers a blend of adventure and relaxation. With its welcoming atmosphere, Millstream Gardens is perfect for families, and you can explore its historical significance while enjoying nature.

Best time to go to Southeast Missouri

The best time to visit Southeast Missouri is dependent on what kind of holiday you are seeking. July is its hottest month on average. At this time, visitor numbers are slightly high and weather is mostly sunny with light rain. January is its coolest month on average. At this time, visitor numbers are slightly low and weather is mostly sunny with light rain.

Calendar Month	Temperature	Precipitation	Cloudiness	Occupancy	Pricing
January	34.9°F (1.6°C)	Light Rain	Mostly Sunny	Slightly Low	Slightly Low
February	38.1°F (3.4000000000000004°C)	Light Rain	Mostly Sunny	Slightly Low	Average
March	48.0°F (8.9°C)	Light Rain	Mostly Sunny	Average	Average
April	57.6°F (14.2°C)	Light Rain	Mostly Sunny	Average	Slightly High
May	67.3°F (19.6°C)	Light Rain	Mostly Sunny	Average	Average
June	76.5°F (24.700000000000003°C)	Light Rain	Mostly Sunny	Slightly High	Slightly High
July	79.2°F (26.200000000000003°C)	Light Rain	Mostly Sunny	Slightly High	Average
August	77.2°F (25.1°C)	Light Rain	Mostly Sunny	Slightly High	Slightly High
September	71.6°F (22.0°C)	Light Rain	Mostly Sunny	Average	Average
October	59.9°F (15.5°C)	Light Rain	Mostly Sunny	Average	Average
November	47.5°F (8.6°C)	Light Rain	Mostly Sunny	Average	Slightly Low
December	39.4°F (4.1000000000000005°C)	Light Rain	Mostly Sunny	Slightly Low	Slightly Low

The nearest major airports for your trip to Southeast Missouri

Traveling to Southeast Missouri can be conveniently done by flying into one of its major airports. St. Louis Lambert International Airport (STL) is located 154.5km away, with nearby hotel options like The Ritz-Carlton and Ameristar Casino Resort, both about 11.3km from the airport. Fort Leonard Wood Regional Airport (TBN) is also 154.5km away, featuring hotels such as Z Loft Extended Stay Hotel, 9.7km from the terminal. Alternatively, Marion Williamson County Regional Airport (MWA) is 133.6km away, offering accommodations like Drury Inn & Suites just 3.2km from the airport. Each airport provides various transportation services for easy access to local hotels.

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Our top choices for Southeast Missouri hotels

1. Shepherd Mountain Inn

2. Madison Inn Lodge

3. Hampton Inn & Suites By Hilton Festus

4. Holiday Inn Express & Suites Perryville by IHG

5. Fairfield Inn & Suites by Marriott Poplar Bluff

6. Drury Inn & Suites Jackson MO

7. Crown Pointe Lodge, BW Signature Collection

8. Fairfield Inn & Suites by Marriott Cape Girardeau

9. Super 8 by Wyndham Farmington

10. Hampton Inn Poplar Bluff

11. La Quinta Inn & Suites by Wyndham Festus - St. Louis South

12. EC Reed's Mercantile and Hotel

13. Drury Plaza Hotel Cape Girardeau Conference Center

14. Holiday Inn Express Hotel & Suites FESTUS - SOUTH ST. LOUIS by IHG

15. Fort Davidson Hotel

16. Drury Inn & Suites Poplar Bluff

17. Baymont Inn and Suites by Wyndham Farmington, MO

18. Fairfield Inn & Suites by Marriott Sikeston

19. Super 8 by Wyndham Perryville

20. The Riverview

Vacation Rentals in Southeast Missouri

The Atrium - A Boutique Hotel

Postcard Cabins St Francois, Outdoor Collection by Marriott Bonvoy

'turtle Rock' - Ironton Cabin w/ Furnished Patio!

Urban Lofts

Tiny Houses of French Village

Lake Wappapello

Walk to Dtwn: Ironton Home in Historic District

Walk to Current River: Ozarks Adventure Home!

Cozy Belgrade Cottage w/ Wood-burning Stove!

Stay near popular Southeast Missouri attractions

Elephant Rocks State Park

Southeast Missouri State University

Lake Wappapello

Century Casino & Hotel Cape Girardeau

Century Casino Caruthersville

Learn more about Southeast Missouri

Top Southeast Missouri Hotel Reviews

Days Inn and Suites by Wyndham Sikeston

Drury Inn & Suites Cape Girardeau

Drury Inn & Suites Hayti Caruthersville

Hampton Inn Poplar Bluff

Hampton Inn Sikeston

Drury Inn & Suites Sikeston, MO

Baymont Inn and Suites by Wyndham Farmington, MO

Postcard Cabins St Francois, Outdoor Collection by Marriott Bonvoy

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

More cheap stays in Southeast Missouri

Baymont Inn and Suites by Wyndham Farmington, MO

Days Inn and Suites by Wyndham Sikeston

Motel 6 Poplar Bluff, MO

Pear Tree Inn Cape Girardeau West

Comfort Inn Festus - St Louis South

Hampton Inn Poplar Bluff

Hotels in Southeast Missouri with star-rating

Find out more about Southeast Missouri

Top reasons to visit Southeast Missouri

Find great hotels near Southeast Missouri

Where to stay near Southeast Missouri

Things to do near Southeast Missouri

Booking tips and Expedia advantages for Southeast Missouri

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