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Our top choices for Southeast Missouri hotels

Postcard Cabins St Francois, Outdoor Collection by Marriott Bonvoy

Postcard Cabins St Francois, Outdoor Collection by Marriott Bonvoy
2.0 star property
French Village
9.8 out of 10, Exceptional, (72 reviews)
"Here is good accommodation! Next time, I hope I will stay here."
United States
YOSHIRO
The price is NT$2,935
NT$4,516 total
includes taxes & fees
Jun 24 - Jun 25
Postcard Cabins St Francois, Outdoor Collection by Marriott Bonvoy

Drury Inn & Suites Jackson MO

Drury Inn & Suites Jackson MO
3.0 star property
Jackson
9.6 out of 10, Exceptional, (1,003 reviews)
"Clean room, friendly staff, good breakfast and dinner variety,large open parking, clean pool and exercise room. All around great stay. "
United States
Jeremy
The price is NT$2,619
NT$2,769 total
includes taxes & fees
Jun 10 - Jun 11
Drury Inn & Suites Jackson MO

Fairfield Inn & Suites by Marriott Cape Girardeau

Fairfield Inn & Suites by Marriott Cape Girardeau
3.0 star property
Cape Girardeau
9.4 out of 10, Exceptional, (189 reviews)
"The hotel was super clean, very friendly, the beds were very comfortable."
United States
Candia
The price is NT$3,095
NT$3,492 total
includes taxes & fees
Jun 2 - Jun 3
Fairfield Inn & Suites by Marriott Cape Girardeau

Tru By Hilton Cape Girardeau

Tru By Hilton Cape Girardeau
2.5 star property
Cape Girardeau
9.6 out of 10, Exceptional, (128 reviews)
"This is a clean, quiet, well designed hotel."
United States
Kendra
The price is NT$3,031
NT$3,449 total
includes taxes & fees
Jun 14 - Jun 15
Tru By Hilton Cape Girardeau

Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)
2.5 star property
Sikeston
8.4 out of 10, Very Good, (782 reviews)
"We were very satisfied with our stay. We will make this a regular stay when traveling to or from Iowa."
United States
Carolyn
The price is NT$2,130
NT$2,427 total
includes taxes & fees
May 26 - May 27
Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

Honeysuckle Inn - Mountain View

Honeysuckle Inn - Mountain View
3.0 star property
Mountain View
8.6 out of 10, Excellent, (357 reviews)
"The Honey Suckle Inn is a decent motel for a night's stay. Not plush, but clean."
United States
Daniel
The price is NT$3,010
NT$3,263 total
includes taxes & fees
May 31 - Jun 1
Honeysuckle Inn - Mountain View

Current River Inn

Current River Inn
3.0 star property
Van Buren
8.2 out of 10, Very Good, (175 reviews)
"This was the cutest little place to stay. The people are friendly, room was clean, and it was safe. I would stay here again. "
United States
Jennifer
The price is NT$3,436
NT$3,719 total
includes taxes & fees
May 27 - May 28
Current River Inn

Hampton Inn Poplar Bluff

Hampton Inn Poplar Bluff
2.5 star property
Poplar Bluff
9.4 out of 10, Exceptional, (849 reviews)
"Nice quiet overnight stay."
United States
Tammy
The price is NT$2,950
NT$3,303 total
includes taxes & fees
May 31 - Jun 1
Hampton Inn Poplar Bluff

The Riverview

The Riverview
4.0 star property
Cape Girardeau
9.4 out of 10, Exceptional, (580 reviews)
"I ALWAYS stay here when I come to Cape! Wonderful, great place!"
United States
Audra
The price is NT$4,175
NT$4,709 total
includes taxes & fees
May 26 - May 27
The Riverview

Hampton Inn By Hilton Dexter

Hampton Inn By Hilton Dexter
2.5 star property
Dexter
9.8 out of 10, Exceptional, (32 reviews)
"The property was clean and the staff was friendly. "
United States
Shelia
The price is NT$3,164
NT$3,553 total
includes taxes & fees
May 31 - Jun 1
Hampton Inn By Hilton Dexter

Super 8 by Wyndham Perryville

Super 8 by Wyndham Perryville
2.0 star property
Perryville
8.4 out of 10, Very Good, (1,001 reviews)
"Enjoyed our stay "
United States
Cynthia
The price is NT$2,226
NT$2,548 total
includes taxes & fees
Jun 2 - Jun 3
Super 8 by Wyndham Perryville

Drury Inn & Suites Sikeston, MO

Drury Inn & Suites Sikeston, MO
3.0 star property
Sikeston
9.6 out of 10, Exceptional, (1,005 reviews)
"Breakfast was good,pool hot tub excellent "
United States
Janica
The price is NT$3,502
NT$4,027 total
includes taxes & fees
Jun 8 - Jun 9
Drury Inn & Suites Sikeston, MO

Fairfield Inn & Suites by Marriott Sikeston

Fairfield Inn & Suites by Marriott Sikeston
3.0 star property
Sikeston
9.4 out of 10, Exceptional, (81 reviews)
"The breakfast was good, the service was good, and the staff was very friendly"
United States
Angela
The price is NT$3,471
NT$3,930 total
includes taxes & fees
Jun 11 - Jun 12
Fairfield Inn & Suites by Marriott Sikeston

Drury Plaza Hotel Cape Girardeau Conference Center

Drury Plaza Hotel Cape Girardeau Conference Center
3.0 star property
Cape Girardeau
9.6 out of 10, Exceptional, (1,005 reviews)
"We found this property to be everything someone would hope for in an overnight stay away from home."
United States
Richard
The price is NT$3,155
NT$3,559 total
includes taxes & fees
Jun 21 - Jun 22
Drury Plaza Hotel Cape Girardeau Conference Center

The Farmstead Hotel

The Farmstead Hotel
2.5 star property
Caruthersville
8.6 out of 10, Excellent, (553 reviews)
"felt safe stayed only in hotel was clean and quiet and felt safe."
United States
Michael
The price is NT$2,998
NT$3,409 total
includes taxes & fees
May 26 - May 27
The Farmstead Hotel

EC Reed's Mercantile and Hotel

EC Reed's Mercantile and Hotel
3.0 star property
Marble Hill
9.6 out of 10, Exceptional, (93 reviews)
"This was such a quaint hotel in Marble Hill. The staff was friendly and attentive and the breakfast and little store are such a fun addition. We will be back!"
United States
Betsy
The price is NT$3,247
NT$3,534 total
includes taxes & fees
May 26 - May 27
EC Reed's Mercantile and Hotel

Baymont Inn and Suites by Wyndham Farmington, MO

Baymont Inn and Suites by Wyndham Farmington, MO
2.5 star property
Farmington
8.0 out of 10, Very Good, (1,009 reviews)
"Very nice, clean, friendly staff"
United States
Patty
The price is NT$1,868
NT$2,033 total
includes taxes & fees
Jun 14 - Jun 15
Baymont Inn and Suites by Wyndham Farmington, MO

Arcadia Academy

Arcadia Academy
3.0 star property
Arcadia
9.8 out of 10, Exceptional, (12 reviews)
"We enjoyed ourselves we've been to plenty of places but we had a great excellent time people the room the food and it was great we will be back¡!!!"
United States
John
The price is NT$4,549
NT$4,935 total
includes taxes & fees
May 31 - Jun 1
Arcadia Academy

Fairfield Inn & Suites by Marriott Poplar Bluff

Fairfield Inn & Suites by Marriott Poplar Bluff
3.0 star property
Poplar Bluff
9.4 out of 10, Exceptional, (905 reviews)
"Nice overnight stop over"
United States
Douglas
The price is NT$3,313
NT$3,743 total
includes taxes & fees
May 31 - Jun 1
Fairfield Inn & Suites by Marriott Poplar Bluff

The Riverstone Hotel Charleston-Sikeston

The Riverstone Hotel Charleston-Sikeston
2.5 star property
Charleston
6.8 out of 10, (412 reviews)
"All very just okay "
United States
Sherry
The price is NT$2,209
NT$2,451 total
includes taxes & fees
May 26 - May 27
The Riverstone Hotel Charleston-Sikeston
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Vacation Rentals in Southeast Missouri

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Explore the family-friendly area of Southeast Missouri—restaurants, wineries, and sights from K Bridge Recreation Area to Clearwater Lake.

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Open Photo by Bill Dillard

Top Southeast Missouri Hotel Reviews

More cheap stays in Southeast Missouri

Hotels in Southeast Missouri with star-rating

Find out more about Southeast Missouri

Top reasons to visit Southeast Missouri

  • Outdoor Adventures: Southeast Missouri is perfect for outdoor enthusiasts, featuring scenic parks and recreational activities that invite exploration.
  • Cultural Experiences: Engage with local culture through campus tours, breweries, and historic civic buildings that reflect the region’s heritage.
  • Charming Neighborhoods: Stroll through friendly neighborhoods that offer a welcoming atmosphere and a taste of local life.
  • Family-Friendly Activities: The area provides a variety of activities suitable for families, making it an ideal vacation spot.
  • Warm Hospitality: Enjoy the warmth of Southern hospitality in a range of charming hotels and lodges.

Find great hotels near Southeast Missouri

Discover a range of charming hotels in Southeast Missouri, perfect for business travelers, adventure seekers, and couples looking for a romantic getaway. Whether you’re searching for the closest accommodations or the best-reviewed options, you’ll find a variety of lodges and hotels that cater to your needs. Embrace the warmth of Southern hospitality and make your stay in Southeast Missouri a memorable one.

  • Madison Inn Lodge: A welcoming motel ideal for business travelers and pet owners alike, Madison Inn Lodge is located 25.7km from Southeast Missouri. This property offers a practical and comfortable stay with amenities tailored for those traveling with pets. Guests appreciate the pet-friendly policy, which includes restrictions to ensure a pleasant environment for all. The lodge features essential amenities designed for business needs, making it a great choice for corporate travelers seeking convenience and comfort.
  • Shepherd Mountain Inn: Positioned 33.8km from Southeast Missouri, Shepherd Mountain Inn stands as a solid choice for business travelers. This hotel combines a professional atmosphere with essential amenities, ensuring a smooth and productive stay. Guests often note the hotel's commitment to providing a comfortable environment, making it suitable for those on work trips or visiting the area for business events. Its strategic location also allows easy access to local attractions, enhancing the overall experience.
  • Alpaca Farm Stay: Located 12.9km from Southeast Missouri, Alpaca Farm Stay offers a unique and adventurous escape for families and couples. This lodge invites guests to immerse themselves in a delightful rural setting, featuring adventure sports options like kayaking, mountain climbing, and fishing nearby. Families will enjoy the shared playground for children, while couples can take advantage of romantic packages. With stunning lake and mountain views available, this property ensures a memorable getaway filled with excitement and relaxation.

Where to stay near Southeast Missouri

In Southeast Missouri, visitors can enjoy a blend of outdoor adventures and picturesque scenery perfect for families. Enjoy leisurely strolls through charming neighborhoods, where friendly locals create a welcoming atmosphere. This region is known for its scenic retreats and recreational activities, making it an ideal vacation spot. With convenient locations and vibrant community vibes, Southeast Missouri promises a delightful experience for all travelers looking to unwind and explore.

  • Central Fredericktown: Nestled about 16.1km from Southeast Missouri, Central Fredericktown is a charming village that attracts visitors year-round, with peak seasons occurring from June to August. This quaint area is ideal for families seeking outdoor adventures and city-themed experiences. Notable activities include exploring the local recreational areas, shopping at the mall center, and visiting the history museum. The village is home to lovely parks and urban greenspaces, providing ample opportunities for relaxation and enjoyment. Central Fredericktown offers a delightful mix of history and recreation that makes it a perfect stop for tourists.
  • Annapolis: Located approximately 22.5km away from Southeast Missouri, Annapolis is a vibrant city known for its stunning scenery and adventurous spirit. The city sees a steady stream of visitors throughout the year, peaking in June, July, and September. Travelers flock to Annapolis for its outdoor activities and picturesque landscapes, including national state parks and rivers. With recreational areas and an arena entertainment facility, there’s no shortage of fun and excitement. Whether you’re hiking through scenic trails or enjoying a day by the water, Annapolis promises an unforgettable experience for all types of adventurers.
  • Des Arc: Situated around 17.7km from Southeast Missouri, Des Arc is a lively city that experiences seasonal fluctuations in visitor numbers, with the summer months from June to August being the most popular. Known for its outdoor activities and natural beauty, Des Arc is a haven for adventure seekers. Visitors can enjoy recreational areas, a water park, and an arena entertainment facility. The nearby national state park, lake, and river provide the perfect backdrop for a day of exploration and relaxation. Des Arc is an excellent destination for those looking to immerse themselves in nature while enjoying a variety of fun-filled activities.

Things to do near Southeast Missouri

Southeast Missouri offers a wealth of outdoor adventures and scenic beauty, perfect for a memorable vacation. Engage in campus tours, outdoor activities, and sports tournaments, or explore local breweries on guided tours. Educational experiences abound, making it an excellent destination for those seeking both fun and learning. With recreational areas and entertainment facilities, there's something for everyone to enjoy in this vibrant region.

Shopping

For a unique shopping experience, visit Red's Flea Market, located 41.8km from Southeast Missouri, offering a variety of local goods. For a more traditional mall experience, check out the Farmington Mineral Area Shopping Center, 48.3km away, featuring entertainment and family-friendly shops.

Recreation

Crane Lake Recreation Area offers a serene environment perfect for relaxation and wellness activities, surrounded by nature's beauty. Silver Mine Recreation Area provides a tranquil setting for rejuvenation, while Arcadia Valley Golf Club combines outdoor sports with stunning landscapes, making it ideal for both leisure and recreation.

Adventure

At Shepherd Mountain Bike Park and Hiking Trails, located 33.8km from Southeast Missouri, enjoy exhilarating mountain biking and scenic hiking. The trails offer a thrilling adventure amidst picturesque landscapes, perfect for outdoor enthusiasts seeking both excitement and natural beauty.

Nightlife

In Southeast Missouri, Cape Girardeau's Riverfront offers vibrant bars and live music, while Sikeston's popular casinos provide exciting gaming and entertainment options. Enjoy the lively atmosphere, delicious local cuisine, and friendly crowds at these nightlife hotspots, perfect for an unforgettable evening out.

*Distances are measured in a straight line; actual driving distances may vary depending on the route.

Booking tips and Expedia advantages for Southeast Missouri

To save money on your trip to Southeast Missouri, consider visiting between November and January when accommodation prices are lower. Tuesdays are the cheapest days to stay, while Saturdays are the most expensive. Use Expedia to find hotel deals by filtering options to suit your budget and preferences, including eco-certified hotels. Additionally, booking a package that combines flights and hotel stays can yield significant savings. Make sure to compare room rates to secure the best deal available for your accommodation.

  • The most and least expensive months on average to stay in a hotel: The cheapest months to stay around Southeast Missouri are November to January, where the prices are slightly lower. This is in comparison to April, June and August, where prices are slightly higher.
  • The most and least expensive days on average to stay in a hotel: The least expensive day to stay around Southeast Missouri is Tuesday. The most expensive day to stay around Southeast Missouri is Saturday.
  • Find cheap hotels on Expedia: Utilize Expedia’s search tool to refine your preferences, such as your budget, desired location, and preferred type of accommodation. For instance, selecting the Eco-certified option will showcase sustainable and environmentally friendly hotels that are currently available. If you're looking for the best prices and deals, simply arrange the price filter from lowest to highest.
  • Consider bundling your trip: You can save money by booking an Expedia package that combines your hotel accommodations in Southeast Missouri with your flights and activities.

Find the best attractions near Southeast Missouri

Southeast Missouri offers a fantastic getaway for outdoor enthusiasts and culture seekers alike. Visitors can explore scenic urban parks, national state parks, and historic civic government buildings. The area is perfect for those looking to connect with nature and experience local culture. Additionally, travelers can check out nearby attractions and visit Southeast Missouri State University for a taste of local education and community life.

  • Walnut Hollow Lake: Experience the serene beauty of Walnut Hollow Lake, located 20.9km from Southeast Missouri. This picturesque lake offers a charming beach, perfect for romantic getaways or family outings amidst stunning scenery.
  • K Bridge Recreation Area: Just 27.4km away, K Bridge Recreation Area is an urban park that caters to families and city dwellers alike. Enjoy outdoor activities surrounded by lush landscapes, making it an ideal spot for a fun-filled day with loved ones.
  • Millstream Gardens Conservation Area: Situated 24.1km from the city, this reserve offers a blend of adventure and relaxation. With its welcoming atmosphere, Millstream Gardens is perfect for families, and you can explore its historical significance while enjoying nature.

Best time to go to Southeast Missouri

The best time to visit Southeast Missouri is dependent on what kind of holiday you are seeking. July is its hottest month on average. At this time, visitor numbers are slightly high and weather is mostly sunny with light rain. January is its coolest month on average. At this time, visitor numbers are slightly low and weather is mostly sunny with light rain.

calendarCalendar MonthtemperatureTemperaturerainPrecipitationmostlyCloudinessoccupationOccupancypricePricing
January34.9°F (1.6°C)Light RainMostly SunnySlightly LowSlightly Low
February38.1°F (3.4000000000000004°C)Light RainMostly SunnySlightly LowAverage
March48.0°F (8.9°C)Light RainMostly SunnyAverageAverage
April57.6°F (14.2°C)Light RainMostly SunnyAverageSlightly High
May67.3°F (19.6°C)Light RainMostly SunnyAverageAverage
June76.5°F (24.700000000000003°C)Light RainMostly SunnySlightly HighSlightly High
July79.2°F (26.200000000000003°C)Light RainMostly SunnySlightly HighAverage
August77.2°F (25.1°C)Light RainMostly SunnySlightly HighSlightly High
September71.6°F (22.0°C)Light RainMostly SunnyAverageAverage
October59.9°F (15.5°C)Light RainMostly SunnyAverageAverage
November47.5°F (8.6°C)Light RainMostly SunnyAverageSlightly Low
December39.4°F (4.1000000000000005°C)Light RainMostly SunnySlightly LowSlightly Low

The nearest major airports for your trip to Southeast Missouri

Traveling to Southeast Missouri can be conveniently done by flying into one of its major airports. St. Louis Lambert International Airport (STL) is located 154.5km away, with nearby hotel options like The Ritz-Carlton and Ameristar Casino Resort, both about 11.3km from the airport. Fort Leonard Wood Regional Airport (TBN) is also 154.5km away, featuring hotels such as Z Loft Extended Stay Hotel, 9.7km from the terminal. Alternatively, Marion Williamson County Regional Airport (MWA) is 133.6km away, offering accommodations like Drury Inn & Suites just 3.2km from the airport. Each airport provides various transportation services for easy access to local hotels.

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