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Find hotels in South Main, Houston from NT$1,735

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Jul 29 - Jul 30
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Discover 6,384 South Main hotels and places to stay, with room rates, reviews, and availability. Most hotels are fully refundable.

Wyndham Houston near NRG Park/Medical Center
Relax in the stylish lounge area with a sofa, coffee table, and potted plants.

Wyndham Houston near NRG Park/Medical Center

3.5 star property
7.2 out of 10, Good, (1145)
"A well kept hotel with great service and atmosphere."
The price is NT$2,478
NT$2,899 total
includes taxes & fees
Aug 6 - Aug 7
Wyndham Houston near NRG Park/Medical Center
Quality Inn & Suites NRG Park - Medical Center
Relax in comfort with a large bed, desk, and TV.

Quality Inn & Suites NRG Park - Medical Center

2.5 star property
6.6 out of 10, (1000)
"Great place to stay right next to the NRG stadium "
The price is NT$1,735
NT$2,030 total
includes taxes & fees
Aug 28 - Aug 29
Quality Inn & Suites NRG Park - Medical Center
Wingate Houston near NRG Park/Medical Center
Situated in a serene courtyard, this gazebo offers a peaceful retreat surrounded by lush greenery and a stone-paved ground.

Wingate Houston near NRG Park/Medical Center

3.0 star property
6.6 out of 10, (929)
"Great location, rooms were hot/warm. Needs a huge make over."
The price is NT$2,210
NT$2,585 total
includes taxes & fees
Aug 11 - Aug 12
Wingate Houston near NRG Park/Medical Center
Candlewood Suites Houston Medical Center by IHG
Classic hotel with a symmetrical facade, featuring a central entrance and multiple windows.

Candlewood Suites Houston Medical Center by IHG

2.5 star property
7.4 out of 10, Good, (787)
"Will definitely be back again!"
The price is NT$2,219
NT$2,596 total
includes taxes & fees
Aug 8 - Aug 9
Candlewood Suites Houston Medical Center by IHG
La Quinta Inn & Suites by Wyndham Deer Park
Stylish hotel with a two-story design, featuring a covered entrance and landscaped gardens.

La Quinta Inn & Suites by Wyndham Deer Park

3.0 star property
8.4 out of 10, Very Good, (396)
"For the price, best in Deer Park"
The price is NT$2,580
NT$3,018 total
includes taxes & fees
Aug 22 - Aug 23
La Quinta Inn & Suites by Wyndham Deer Park
La Quinta Inn & Suites by Wyndham Houston East at Sheldon Rd
Relax in a cozy space with a comfortable sofa, a neatly made bed, and a desk for work or study.

La Quinta Inn & Suites by Wyndham Houston East at Sheldon Rd

3.5 star property
9.2 out of 10, Wonderful, (1001)
"My second time staying here and it was great! Always clean and quiet, with gated parking!!"
The price is NT$2,272
NT$2,613 total
includes taxes & fees
Aug 3 - Aug 4
La Quinta Inn & Suites by Wyndham Houston East at Sheldon Rd
Sonesta Simply Suites Houston – NASA Clear Lake
Enjoy cooking in this well-equipped kitchen with a stainless steel refrigerator, microwave, and coffee maker.

Sonesta Simply Suites Houston – NASA Clear Lake

2.5 star property
8.2 out of 10, Very Good, (972)
"I always enjoy my extended stay in Sonesta at Clear Lake. The property is well maintained, the staff is caring and friendly and the location is very good."
The price is NT$1,762
NT$2,062 total
includes taxes & fees
Aug 11 - Aug 12
Sonesta Simply Suites Houston – NASA Clear Lake
SureStay Hotel by Best Western Deer Park
Two single beds with matching headboards and footboards, a flat-screen TV, and a wooden desk with chair.

SureStay Hotel by Best Western Deer Park

2.5 star property
8.4 out of 10, Very Good, (250)
"Good Place to stay "
The price is NT$2,077
NT$2,430 total
includes taxes & fees
Jul 30 - Jul 31
SureStay Hotel by Best Western Deer Park
Platinum Inn & Suites Webster
Two single beds with white linens and dark headboards, a flat-screen TV, and two bedside tables with lamps.

Platinum Inn & Suites Webster

2.5 star property
8.0 out of 10, Very Good, (46)
"Very good staff, always attended to needs quickly. Wonderful place to stay. "
The price is NT$1,917
NT$2,243 total
includes taxes & fees
Jul 30 - Jul 31
Platinum Inn & Suites Webster
Best Western Webster Hotel, Nasa
Relax by the serene pool surrounded by lounge chairs and a shaded seating area.

Best Western Webster Hotel, Nasa

2.5 star property
7.6 out of 10, Good, (1000)
"Great stay"
The price is NT$1,890
NT$2,211 total
includes taxes & fees
Aug 7 - Aug 8
Best Western Webster Hotel, Nasa
La Quinta Inn & Suites by Wyndham Houston Channelview
La Quinta offers a welcoming entrance with a covered area and multiple windows.

La Quinta Inn & Suites by Wyndham Houston Channelview

3.5 star property
8.4 out of 10, Very Good, (783)
"Convenient location "
The price is NT$2,723
NT$3,186 total
includes taxes & fees
Aug 17 - Aug 18
La Quinta Inn & Suites by Wyndham Houston Channelview
Palace Inn Blue Houston East Beltway 8
Efficient kitchenette with refrigerator, water dispenser, and washing machine.

Palace Inn Blue Houston East Beltway 8

2.5 star property
9.0 out of 10, Wonderful, (297)
"Absolutely love, this place peace and quiet nice rooms, friendly staff"
The price is NT$2,252
NT$2,590 total
includes taxes & fees
Aug 5 - Aug 6
Palace Inn Blue Houston East Beltway 8
La Quinta Inn & Suites by Wyndham Pasadena North
Relax in the stylish lobby with a central seating area, flat-screen TV, and fireplace.

La Quinta Inn & Suites by Wyndham Pasadena North

3.0 star property
7.6 out of 10, Good, (598)
"Will go again I like this hotel!!!!"
The price is NT$2,326
NT$2,722 total
includes taxes & fees
Aug 10 - Aug 11
La Quinta Inn & Suites by Wyndham Pasadena North
Bluestar Inn
Two single beds with black headboards and beige bedding, a nightstand with a telephone, and a wooden floor.

Bluestar Inn

2.5 star property
9.0 out of 10, Wonderful, (254)
"Nice place at a good rate "
The price is NT$1,767
NT$2,067 total
includes taxes & fees
Jul 31 - Aug 1
Bluestar Inn
Best Western Plus Pasadena Inn and Suites
Welcome to our hotel lobby, featuring a reception desk, comfortable seating area, and a large screen displaying engaging content.

Best Western Plus Pasadena Inn and Suites

2.5 star property
8.6 out of 10, Excellent, (424)
"Excellent place to stay"
The price is NT$2,728
NT$3,192 total
includes taxes & fees
Aug 6 - Aug 7
Best Western Plus Pasadena Inn and Suites
Best Western Plus Heritage Inn
Welcome to our lobby, featuring a reception desk, comfortable seating area, and convenient vending machine.

Best Western Plus Heritage Inn

3.0 star property
8.0 out of 10, Very Good, (700)
"The best stay i have ever had ! "
The price is NT$2,306
NT$2,698 total
includes taxes & fees
Aug 8 - Aug 9
Best Western Plus Heritage Inn
Woodspring Suites South Houston Hobby
Relax in a spacious room with a large bed, sofa, and comfortable seating area.

Woodspring Suites South Houston Hobby

2.5 star property
8.0 out of 10, Very Good, (247)
"Nice stay"
The price is NT$1,893
NT$2,215 total
includes taxes & fees
Jul 30 - Jul 31
Woodspring Suites South Houston Hobby
Palace Inn Blue Edgebrook
Enjoy a morning coffee at the kitchen's coffee station, overlooking the outdoors through the large window.

Palace Inn Blue Edgebrook

2.5 star property
9.6 out of 10, Exceptional, (126)
"Really great hospitality"
The price is NT$2,305
NT$2,777 total
includes taxes & fees
Jul 30 - Jul 31
Palace Inn Blue Edgebrook
Sonesta Essential Houston Hobby Airport
Relax in the stylish lobby with a seating area, flat-screen TV, and reception desk.

Sonesta Essential Houston Hobby Airport

2.5 star property
6.4 out of 10, (1007)
"I love the breakfast."
The price is NT$2,071
NT$2,596 total
includes taxes & fees
Jul 30 - Jul 31
Sonesta Essential Houston Hobby Airport
Days Inn & Suites by Wyndham Houston Hobby Airport
Classic hotel with a symmetrical facade and central arched entrance, offering a welcoming appearance.

Days Inn & Suites by Wyndham Houston Hobby Airport

2.5 star property
8.6 out of 10, Excellent, (1001)
"It was good stay"
The price is NT$2,337
NT$2,734 total
includes taxes & fees
Jul 30 - Jul 31
Days Inn & Suites by Wyndham Houston Hobby Airport
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Where to stay in South Main

Find the best South Main areas and neighborhoods for the activities you enjoy most.
Discovery Green which includes a city, central business district and a high rise building
Downtown Houston map

Downtown Houston

3 out of top 10 points of interest in this area

Largest central business district in Texas, this area boasts major league sports venues, a vibrant Theater District, and shopping options like GreenStreet. Easily navigate with public transportation options like METRORail and bus lines.

The Galleria map

The Galleria

Travelers to The Galleria praise its popular shops. If you've got some more time to explore, be sure to make a stop by The Galleria and Gerald D. Hines Waterwall Park.

Texas Medical Center map

Texas Medical Center

1 out of top 10 points of interest in this area

Boasting the world's largest medical complex, this Houston neighborhood offers access to over 60 medical institutions and is served by the METRORail Red Line. Explore the John P. McGovern Historical Collections and Research Center for a unique experience.

Menil Collection which includes art and interior views
Montrose map

Montrose

Unique features of Montrose include the theaters and museums. Make a stop by Menil Collection or Westheimer Rd while you're exploring the area.

Houston featuring a city and a high rise building
Houston Central Business District map

Houston Central Business District

If you're spending time in Houston Central Business District, check out sights like Toyota Center or House of Blues Houston and hop on the metro to see more the city at Bell Station or Main Street Square Station.

Top South Main Hotel Reviews

Hyatt Regency Houston Downtown

Hyatt Regency Houston Downtown

10/10 Excellent
"The property is really nice, the views are amazing, great time with the family"
Hector 2-night trip
Posted 16 hours ago
Hyatt Regency Houston Downtown

Frequently asked questions

What is South Main like?

You'll be sure to have fun visiting Houston's South Main neighborhood. Consider a visit to NRG Park as part of your South Main travel plans.

Where is the best hotel for a stay in South Main?

Based on Expedia customer reviews, Comfort Suites near Texas Medical Center - NRG Stadium is the highest ranked property in South Main. This hotel is a short 9-minute walk from NRG Stadium, and it offers free breakfast and free parking. Other top choices in the neighborhood include Candlewood Suites Houston Medical Center by IHG and Quality Inn & Suites NRG Park - Medical Center.

How many hotels will I be able to find in South Main?

If you're searching for places to stay in Houston, Expedia has something to meet your needs with 58 South Main hotels and other accommodations to choose from.

If I need to cancel my hotel reservation in South Main, will I receive a refund?

Yes, the majority of hotel bookings are refundable provided that you cancel before the accommodation's cancellation deadline, which is often 24 or 48 hours before your scheduled arrival. If you booked a non-refundable reservation, you might be able to still cancel and be given a refund within a 24-hour period of your booking. Enter dates in and click on "Search", then use the filter option "fully refundable" to get the best options available in South Main.

Where can I learn more about changing or cancelling my trip to South Main?

For more details about changing or cancelling your trip to South Main, head over to our customer service page.

What can I see and do in this Houston neighborhood?

NRG Park is an attraction you might want to check out while you're in South Main. While you're out sightseeing in Houston, be sure to visit other sights like NRG Stadium or NRG Arena.

How can I get around South Main and the greater Houston area?

Ready to get out and explore the city? Fannin South Station is the closest metro station.