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Find hotels in South Main, Houston from NT$1,774

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Discover 6,472 South Main hotels and places to stay, with room rates, reviews, and availability. Most hotels are fully refundable.

Hotel Park Place
Deluxe Room, 1 King Bed, Non Smoking, Kitchenette | 1 bedroom, premium bedding, desk, laptop workspace

Hotel Park Place

2.5 star property
8.6 out of 10, Excellent, (188)
"Great place highly recomend"
The price is NT$1,932
NT$2,261 total
includes taxes & fees
Sep 23 - Sep 24
Hotel Park Place
Americas Best Value Inn NRG Park Medical Center
Free self parking

Americas Best Value Inn NRG Park Medical Center

2.0 star property
7.8 out of 10, Good, (778)
"The beds were awesome and very clean rooms. "
The price is NT$1,928
NT$2,256 total
includes taxes & fees
Sep 26 - Sep 27
Americas Best Value Inn NRG Park Medical Center
Days Inn & Suites by Wyndham Downtown/University of Houston
Exterior

Days Inn & Suites by Wyndham Downtown/University of Houston

2.0 star property
8.0 out of 10, Very Good, (720)
"Great Stay for the cost"
The price is NT$1,774
NT$2,075 total
includes taxes & fees
Sep 15 - Sep 16
Days Inn & Suites by Wyndham Downtown/University of Houston
Wingate Houston near NRG Park/Medical Center
Gazebo

Wingate Houston near NRG Park/Medical Center

3.0 star property
6.6 out of 10, (937)
"Walking distance to NRG Stadium "
The price is NT$2,396
NT$2,803 total
includes taxes & fees
Sep 16 - Sep 17
Wingate Houston near NRG Park/Medical Center
Wyndham Houston near NRG Park/Medical Center
Lobby

Wyndham Houston near NRG Park/Medical Center

3.5 star property
7.2 out of 10, Good, (1145)
"I use the app and its been really helpful for our trips we have planned so far."
The price is NT$2,972
NT$3,477 total
includes taxes & fees
Sep 14 - Sep 15
Wyndham Houston near NRG Park/Medical Center
Quality Inn & Suites NRG Park - Medical Center
1 bedroom, hypo-allergenic bedding, in-room safe, individually decorated

Quality Inn & Suites NRG Park - Medical Center

2.5 star property
6.6 out of 10, (1001)
"Wonderful experience absolutely love my stay"
The price is NT$1,883
NT$2,203 total
includes taxes & fees
Sep 29 - Sep 30
Quality Inn & Suites NRG Park - Medical Center
Candlewood Suites Houston Medical Center by IHG
Exterior

Candlewood Suites Houston Medical Center by IHG

2.5 star property
7.4 out of 10, Good, (796)
"Will definitely be back again!"
The price is NT$2,244
NT$2,626 total
includes taxes & fees
Sep 23 - Sep 24
Candlewood Suites Houston Medical Center by IHG
SpringHill Suites by Marriott Houston Intercontinental Arprt
Terrace/patio

SpringHill Suites by Marriott Houston Intercontinental Arprt

3.0 star property
9.0 out of 10, Wonderful, (1487)
"Nice hotel for a night close to the airport"
The price is NT$3,059
NT$3,579 total
includes taxes & fees
Sep 26 - Sep 27
SpringHill Suites by Marriott Houston Intercontinental Arprt
Houston Marriott South at Hobby Airport
Lobby

Houston Marriott South at Hobby Airport

3.5 star property
8.8 out of 10, Excellent, (1218)
"Very nice stay "
The price is NT$2,766
NT$3,324 total
includes taxes & fees
Sep 19 - Sep 20
Houston Marriott South at Hobby Airport
Americas Best Value Inn Medical Center Downtown
Desk, free WiFi, bed sheets, alarm clocks

Americas Best Value Inn Medical Center Downtown

2.0 star property
8.0 out of 10, Very Good, (999)
"Good location "
The price is NT$2,134
NT$2,496 total
includes taxes & fees
Sep 22 - Sep 23
Americas Best Value Inn Medical Center Downtown
Platinum Inn & Suites Webster
Exclusive Room, Multiple Beds, Non Smoking | Premium bedding, desk, iron/ironing board, free WiFi

Platinum Inn & Suites Webster

3.0 star property
7.8 out of 10, Good, (1002)
"Location "
The price is NT$1,774
NT$2,075 total
includes taxes & fees
Sep 24 - Sep 25
Platinum Inn & Suites Webster
Hampton Inn & Suites Houston-Bush Intercontinental Aprt
Exterior

Hampton Inn & Suites Houston-Bush Intercontinental Aprt

3.0 star property
8.8 out of 10, Excellent, (1525)
"It was clean, quiet, and convenient to the airport. "
The price is NT$2,396
NT$2,818 total
includes taxes & fees
Sep 28 - Sep 29
Hampton Inn & Suites Houston-Bush Intercontinental Aprt
Bluestar Inn
Individually furnished, desk, iron/ironing board, free WiFi

Bluestar Inn

2.5 star property
9.0 out of 10, Wonderful, (261)
"Nice will go again "
The price is NT$1,820
NT$2,129 total
includes taxes & fees
Sep 14 - Sep 15
Bluestar Inn
Palace Inn 290 & Jones Rd
Room, 1 King Bed, Non Smoking | View from room

Palace Inn 290 & Jones Rd

2.5 star property
8.8 out of 10, Excellent, (463)
"Staff was friendly, rooms were neat and clean. The area was quiet."
The price is NT$1,784
NT$2,088 total
includes taxes & fees
Sep 17 - Sep 18
Palace Inn 290 & Jones Rd
Americas Best Value Inn & Suites NE Houston Downtown I-610
Suite, 2 Queen Beds, Non Smoking, Kitchenette | Room amenity

Americas Best Value Inn & Suites NE Houston Downtown I-610

2.0 star property
8.6 out of 10, Excellent, (614)
"Love my stay! Will def come back"
The price is NT$2,014
NT$2,356 total
includes taxes & fees
Sep 22 - Sep 23
Americas Best Value Inn & Suites NE Houston Downtown I-610
Holiday Inn Express & Suites Houston – Downtown North by IHG
Exterior

Holiday Inn Express & Suites Houston – Downtown North by IHG

2.5 star property
9.2 out of 10, Wonderful, (570)
"The hotel is very clean and the staff is super friendly and helpful."
The price is NT$3,236
NT$3,786 total
includes taxes & fees
Sep 22 - Sep 23
Holiday Inn Express & Suites Houston – Downtown North by IHG
La Quinta Inn & Suites by Wyndham Houston East at Sheldon Rd
Pillowtop beds, desk, iron/ironing board, WiFi

La Quinta Inn & Suites by Wyndham Houston East at Sheldon Rd

3.5 star property
9.2 out of 10, Wonderful, (1002)
"The property is good and breakfast is nice..:)"
The price is NT$2,305
NT$2,651 total
includes taxes & fees
Sep 28 - Sep 29
La Quinta Inn & Suites by Wyndham Houston East at Sheldon Rd
La Quinta Inn & Suites by Wyndham Houston Hobby Airport
Lobby lounge

La Quinta Inn & Suites by Wyndham Houston Hobby Airport

3.0 star property
8.0 out of 10, Very Good, (1001)
"Close to the airport "
The price is NT$1,774
NT$2,076 total
includes taxes & fees
Sep 15 - Sep 16
La Quinta Inn & Suites by Wyndham Houston Hobby Airport
Best Western Plus Hobby Airport Inn & Suites
Exterior

Best Western Plus Hobby Airport Inn & Suites

2.5 star property
8.8 out of 10, Excellent, (1273)
"Great place to stay with friendly people."
The price is NT$2,313
NT$2,706 total
includes taxes & fees
Sep 22 - Sep 23
Best Western Plus Hobby Airport Inn & Suites
Best Western Webster Hotel, Nasa
Seasonal outdoor pool, pool umbrellas, sun loungers

Best Western Webster Hotel, Nasa

2.5 star property
7.6 out of 10, Good, (1002)
"Staff is great "
The price is NT$1,896
NT$2,218 total
includes taxes & fees
Sep 25 - Sep 26
Best Western Webster Hotel, Nasa
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Where to stay in South Main

Find the best South Main areas and neighborhoods for the activities you enjoy most.
Discovery Green which includes a city, central business district and a high rise building

Downtown Houston

3 out of top 10 points of interest in this area

Largest central business district in Texas, this area boasts major league sports venues, a vibrant Theater District, and shopping options like GreenStreet. Easily navigate with public transportation options like METRORail and bus lines.

The Galleria

Travelers to The Galleria praise its popular shops. If you've got some more time to explore, be sure to make a stop by The Galleria and Williams Tower.

Texas Medical Center

1 out of top 10 points of interest in this area

Boasting the world's largest medical complex, this Houston neighborhood offers access to over 60 medical institutions and is served by the METRORail Red Line. Explore the John P. McGovern Historical Collections and Research Center for a unique experience.

Houston featuring a city and a high rise building

Houston Central Business District

If you're spending time in Houston Central Business District, check out sights like Toyota Center or House of Blues Houston and hop on the metro to see more the city at Bell Station or Main Street Square Station.

Menil Collection which includes art and interior views

Montrose

Unique features of Montrose include the theaters and museums. Make a stop by Menil Collection or Houston Center for Photography while you're exploring the area.

Top South Main Hotel Reviews

The Whitehall Houston

The Whitehall Houston

10/10 Excellent
"Great property. Nice and clean rooms. Staff was very attentive and helpful."
Tyra 4-night trip
Posted 3 days ago
The Whitehall Houston

Explore a world of travel with Expedia

Explore a world of travel with Expedia

Frequently asked questions

What is South Main like?

You'll be sure to have fun visiting Houston's South Main neighborhood. Consider a visit to NRG Park as part of your South Main travel plans.

Where is the best hotel for a stay in South Main?

Based on Expedia customer reviews, Comfort Suites near Texas Medical Center - NRG Stadium is the highest ranked property in South Main. This hotel is a short 9-minute walk from NRG Stadium, and it offers free breakfast and free parking. Other top choices in the neighborhood include Quality Inn & Suites NRG Park - Medical Center and Wyndham Houston near NRG Park/Medical Center.

How many hotels will I be able to find in South Main?

If you're searching for places to stay in Houston, Expedia has something to meet your needs with 64 South Main hotels and other accommodations to choose from.

If I need to cancel my hotel reservation in South Main, will I receive a refund?

Yes, the majority of hotel bookings are refundable provided that you cancel before the accommodation's cancellation deadline, which is often 24 or 48 hours before your scheduled arrival. If you booked a non-refundable reservation, you might be able to still cancel and be given a refund within a 24-hour period of your booking. Enter dates in and click on "Search", then use the filter option "fully refundable" to get the best options available in South Main.

Where can I learn more about changing or cancelling my trip to South Main?

For more details about changing or cancelling your trip to South Main, head over to our customer service page.

What can I see and do in this Houston neighborhood?

NRG Park is an attraction you might want to check out while you're in South Main. While you're out sightseeing in Houston, be sure to visit other sights like NRG Stadium or NRG Arena.

How can I get around South Main and the greater Houston area?

Ready to get out and explore the city? Fannin South Station is the closest metro station.