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Oct 30 - Nov 1
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Nov 6 - Nov 8

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Our top choices for Siesta Isle hotels

A row of turquoise Adirondack chairs with umbrellas, a wooden deck, and a marina in the background.

1. Latitude 26 Waterfront Boutique Resort - Fort Myers Beach

Latitude 26 Waterfront Boutique Resort - Fort Myers Beach
2.5 star property
Siesta Isle
9.0 out of 10, Wonderful, (1,000 reviews)
"I like this hotel we have been twice"
United States
Giovanna
The price is NT$3,216
NT$3,586 total
includes taxes & fees
Nov 2 - Nov 3
Latitude 26 Waterfront Boutique Resort - Fort Myers Beach
An outdoor patio with tables and chairs, umbrellas, and a pool in the background.

2. Holiday Inn Express & Suites Ft Myers Beach-Sanibel Gateway by IHG

Holiday Inn Express & Suites Ft Myers Beach-Sanibel Gateway by IHG
2.5 star property
2.7 km from Siesta Isle
9.2 out of 10, Wonderful, (1,000 reviews)
"Clean Hotel! Convenient for one night stay, close to airport and beaches."
United States
Kimberly
The price is NT$3,004
NT$3,349 total
includes taxes & fees
Nov 1 - Nov 2
Holiday Inn Express & Suites Ft Myers Beach-Sanibel Gateway by IHG
A spacious lobby with a high ceiling, a seating area with a sofa and chairs, a small round table, and a decorative wall with artwork.

3. Hampton Inn & Suites Fort Myers Beach/Sanibel Gateway

Hampton Inn & Suites Fort Myers Beach/Sanibel Gateway
3.0 star property
2.6 km from Siesta Isle
8.8 out of 10, Excellent, (1,000 reviews)
"One of the best properties I’ve stayed in and the staff were excellent."
United States
Christina
The price is NT$2,953
NT$3,292 total
includes taxes & fees
Oct 31 - Nov 1
Hampton Inn & Suites Fort Myers Beach/Sanibel Gateway
A large, clear swimming pool with multiple lounge areas and palm trees.

4. Margaritaville Beach Resort Fort Myers

Margaritaville Beach Resort Fort Myers
4.0 star property
2.6 km from Siesta Isle
9.0 out of 10, Wonderful, (2,714 reviews)
"Our favorite place to stay."
United States
Anastasia
The price is NT$6,098
NT$8,427 total
includes taxes & fees
Nov 15 - Nov 16
Margaritaville Beach Resort Fort Myers
A swimming pool with a rock arch structure, a multi-story building with balconies, and palm trees in the background.

5. Pink Shell Beach Resort and Marina

Pink Shell Beach Resort and Marina
4.0 star property
1.8 km from Siesta Isle
9.4 out of 10, Exceptional, (1,486 reviews)
"It's nice place to stay"
United States
Mario
The price is NT$6,954
NT$9,887 total
includes taxes & fees
Nov 2 - Nov 3
Pink Shell Beach Resort and Marina
A modern dining area with wooden flooring, white chairs, and large windows offering a view of the beach.

6. Best Western Plus Beach Resort

Best Western Plus Beach Resort
2.5 star property
2.2 km from Siesta Isle
9.4 out of 10, Exceptional, (1,003 reviews)
"Convenient location, friendly staff and clean rooms."
United States
Stacy
The price is NT$7,024
NT$7,831 total
includes taxes & fees
Nov 15 - Nov 16
Best Western Plus Beach Resort
A spacious dining area with multiple tables and chairs, large windows, and a modern chandelier.

7. Residence Inn by Marriott Fort Myers Sanibel

Residence Inn by Marriott Fort Myers Sanibel
3.0 star property
2.7 km from Siesta Isle
8.8 out of 10, Excellent, (1,000 reviews)
"The hotel was in a great location, very clean and had great breakfast options."
United States
jennifer
The price is NT$2,918
NT$3,253 total
includes taxes & fees
Nov 1 - Nov 2
Residence Inn by Marriott Fort Myers Sanibel
A hotel pool area with multiple lounge chairs and umbrellas, surrounded by a fence and palm trees.

8. La Quinta Inn & Suites by Wyndham Ft. Myers-Sanibel Gateway

La Quinta Inn & Suites by Wyndham Ft. Myers-Sanibel Gateway
3.0 star property
2.3 km from Siesta Isle
8.2 out of 10, Very good, (1,396 reviews)
"The staff was very helpful during my stay."
United States
Samantha
The price is NT$2,723
NT$3,037 total
includes taxes & fees
Nov 4 - Nov 5
La Quinta Inn & Suites by Wyndham Ft. Myers-Sanibel Gateway
A swimming pool with lounge chairs and umbrellas, surrounded by palm trees and a stone archway.

9. The Lighthouse Resort Inn & Suites

The Lighthouse Resort Inn & Suites
3.0 star property
2.4 km from Siesta Isle
8.6 out of 10, Excellent, (1,841 reviews)
"excellent place to stay"
United States
Shayne
The price is NT$2,611
NT$3,560 total
includes taxes & fees
Nov 2 - Nov 3
The Lighthouse Resort Inn & Suites
A waterfront property with a wooden deck, outdoor seating, and a covered patio area.

10. Matanzas Inn Bayside Resort and Marina

Matanzas Inn Bayside Resort and Marina
3.0 star property
2.1 km from Siesta Isle
9.4 out of 10, Exceptional, (1,000 reviews)
"I love Matanza. It's in a great location, walking distance to everything. I enjoyed sitting on the canal/bay and seeing all the wildlife, especially Manatee! We stayed in the 2 bedroom and it was perfect!"
United States
Tammy
The price is NT$5,791
NT$7,268 total
includes taxes & fees
Oct 30 - Oct 31
Matanzas Inn Bayside Resort and Marina
A boat named 'Carolina Daze' with a covered seating area, a steering wheel, and a view of a waterway with greenery and buildings in the background.

11. Latitude 26 Waterfront Resort & Marina

Latitude 26 Waterfront Resort & Marina
3.0 star property
1.1 km from Siesta Isle
8.6 out of 10, Excellent, (1,000 reviews)
"Great place to stay, especially on a fishing trip!"
United States
Mitchel
The price is NT$3,029
NT$3,378 total
includes taxes & fees
Nov 1 - Nov 2
Latitude 26 Waterfront Resort & Marina
A balcony with wicker furniture, a view of a beach, and a clear sky.

12. Lani Kai Beachfront Resort

Lani Kai Beachfront Resort
3.5 star property
2.7 km from Siesta Isle
8.8 out of 10, Excellent, (2,155 reviews)
"It was great to be right on the beach! The restaurants were also good."
United States
Tanya
The price is NT$3,650
NT$4,793 total
includes taxes & fees
Nov 3 - Nov 4
Lani Kai Beachfront Resort
A beach view from a balcony with a pool, palm trees, and a building with a balcony.

13. Edison Beach House

Edison Beach House
3.5 star property
2.3 km from Siesta Isle
9.4 out of 10, Exceptional, (1,957 reviews)
"One of the best locations on Ft Myers Beach"
United States
mark
The price is NT$6,326
NT$8,319 total
includes taxes & fees
Nov 5 - Nov 6
Edison Beach House
A beachfront hotel with a pool, beach, and ocean view.

14. DiamondHead Beach Resort

DiamondHead Beach Resort
3.5 star property
2.9 km from Siesta Isle
9.2 out of 10, Wonderful, (1,325 reviews)
"excellent place will stay again!"
United States
James Edward
The price is NT$6,492
NT$8,503 total
includes taxes & fees
Nov 18 - Nov 19
DiamondHead Beach Resort
A waterfront property with a dock, a white picket fence, and a clear blue sky.

15. The Bay Inn at Lani Kai

The Bay Inn at Lani Kai
3.0 star property
2.7 km from Siesta Isle
7.8 out of 10, Good, (533 reviews)
"Clean room, helpful staff, very close to the beach."
United States
Andrea
The price is NT$3,472
NT$4,595 total
includes taxes & fees
Nov 1 - Nov 2
The Bay Inn at Lani Kai
A hotel entrance with a sign reading 'Candlewood Suites' and a parking lot with a handicapped parking space.

16. Candlewood Suites Fort Myers Sanibel Gateway by IHG

Candlewood Suites Fort Myers Sanibel Gateway by IHG
3.0 star property
4.9 km from Siesta Isle
7.6 out of 10, Good, (1,002 reviews)
"I was satisfied with the price for a short stay."
United States
James
The price is NT$2,172
NT$2,422 total
includes taxes & fees
Nov 1 - Nov 2
Candlewood Suites Fort Myers Sanibel Gateway by IHG
A hotel room with two beds, a wooden headboard, a nightstand with a lamp, and a window with curtains.

17. Holiday Inn Express Cape Coral-Fort Myers Area by IHG

Holiday Inn Express Cape Coral-Fort Myers Area by IHG
2.5 star property
9.7 km from Siesta Isle
9.4 out of 10, Exceptional, (1,730 reviews)
"Excellent hotel if you want to stay there for a few days"
United States
Gabriel
The price is NT$3,242
NT$3,615 total
includes taxes & fees
Nov 2 - Nov 3
Holiday Inn Express Cape Coral-Fort Myers Area by IHG
A waterfront hotel with multiple buildings, a dock, and a calm body of water reflecting the structures.

18. Marriott Sanibel Harbour Resort & Spa

Marriott Sanibel Harbour Resort & Spa
4.0 star property
5.7 km from Siesta Isle
8.6 out of 10, Excellent, (1,000 reviews)
"I love everything about this hotel"
United States
Yunior
The price is NT$6,718
NT$8,625 total
includes taxes & fees
Nov 12 - Nov 13
Marriott Sanibel Harbour Resort & Spa
An outdoor patio with a barbecue area, seating, and string lights.

19. Homewood Suites by Hilton Fort Myers Airport/FGCU

Homewood Suites by Hilton Fort Myers Airport/FGCU
3.0 star property
17 km from Siesta Isle
9.4 out of 10, Exceptional, (1,000 reviews)
"Great property good location friendly staff very clean room good breakfast"
United States
Leo
The price is NT$3,996
NT$4,455 total
includes taxes & fees
Nov 22 - Nov 23
Homewood Suites by Hilton Fort Myers Airport/FGCU
A resort with multiple-story buildings, palm trees, and a well-maintained lawn.

20. Sanibel Island Beach Resort

Sanibel Island Beach Resort
3.0 star property
10.1 km from Siesta Isle
9.2 out of 10, Wonderful, (2,386 reviews)
"Love this place - always have a nice time here -"
United States
Pablo
The price is NT$6,452
NT$8,098 total
includes taxes & fees
Nov 1 - Nov 2
Sanibel Island Beach Resort
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Compare popular hotels in Siesta Isle

Property
Property class
Guest rating
Breakfast included
Pool
Spa
Pet friendly
WiFi included
A row of turquoise Adirondack chairs with umbrellas, a wooden deck, and a marina in the background.
Latitude 26 Waterfront Boutique Resort - Fort Myers Beach
2.5 star property
9.0
Wonderful
1,000 reviews
View
A spacious lobby with a high ceiling, a seating area with a sofa and chairs, a small round table, and a decorative wall with artwork.
Hampton Inn & Suites Fort Myers Beach/Sanibel Gateway
3.0 star property
8.8
Excellent
1,000 reviews
View
An outdoor patio with tables and chairs, umbrellas, and a pool in the background.
Holiday Inn Express & Suites Ft Myers Beach-Sanibel Gateway by IHG
2.5 star property
9.2
Wonderful
1,000 reviews
View
A spacious dining area with multiple tables and chairs, large windows, and a modern chandelier.
Residence Inn by Marriott Fort Myers Sanibel
3.0 star property
8.8
Excellent
1,000 reviews
View
A hotel pool area with multiple lounge chairs and umbrellas, surrounded by a fence and palm trees.
La Quinta Inn & Suites by Wyndham Ft. Myers-Sanibel Gateway
3.0 star property
8.2
Very good
1,396 reviews
View

Hotels recommended for families in Siesta Isle

A row of turquoise Adirondack chairs with umbrellas, a wooden deck, and a marina in the background.

Latitude 26 Waterfront Boutique Resort - Fort Myers Beach

Latitude 26 Waterfront Boutique Resort - Fort Myers Beach
2.5 star property
Siesta Isle
9.0 out of 10, Wonderful, (1,000)
The price is NT$3,216
NT$3,586 total
includes taxes & fees
Nov 2 - Nov 3
Latitude 26 Waterfront Boutique Resort - Fort Myers Beach

Where to stay in Siesta Isle

Find the best Siesta Isle areas and neighborhoods for the activities you enjoy most.
A sunset over a calm sea with trees framing the view.

Mid Island

While visiting Mid Island, you might make a stop by sights like Estero Boulevard Beach and Sterling Ave Beach.

A pier extending into the water with two gazebos at the end, under a sunset sky.

South Island

While visiting South Island, you might make a stop by sights like Santini Marina Shopping Plaza and Castle Beach.

A coastal town with a marina, residential buildings, and a clear view of the ocean.

TP Hill's

When in TP Hill's, you can plan a visit to Key West Express and Estero Boulevard Beach, some noteworthy sights in the nearby area.

A beach at sunset with a pink and purple sky, people walking, and a lifeguard tower in the distance.
Photo by Abby Chase
Open Photo by Abby Chase

Downtown Fort Myers Beach

If you're spending some time in Downtown Fort Myers Beach, Lynn Hall Memorial Park and Estero Boulevard Beach are top sights worth seeing.

A coastal town with a beach, buildings, and a road.

Winklers

While Winklers might not have many sights to explore, venturing just a little farther will lead you to top things to see and do like Key West Express and Estero Boulevard Beach.

Top Siesta Isle Hotel Reviews

Margaritaville Beach Resort Fort Myers

Margaritaville Beach Resort Fort Myers

10/10 Excellent
"What a Great place all was amazing didn’t leave the resort lots to do with ate and drink !"
Maria 2-night trip
Posted 2 hours ago
Margaritaville Beach Resort Fort Myers

Frequently asked questions

What is Siesta Isle like?
Travelers will be sure to find plenty to entertain them in Fort Myers Beach's Siesta Isle neighborhood. Consider a visit to San Carlos Bay - Bunche Beach Preserve as part of your Siesta Isle travel plans.
Where is the best place to stay in Siesta Isle?
Based on our traveler data, Latitude 26 Waterfront Boutique Resort - Fort Myers Beach is one of the top choices for your stay in Siesta Isle. This hotel offers a marina and free breakfast.
How many hotels will I find in Siesta Isle?
If you're searching for places to stay in Fort Myers Beach, Expedia has something to meet your needs with 27 Siesta Isle hotels and other accommodations to choose from.
If I need to cancel my hotel reservation in Siesta Isle, will I receive a refund?
Yes, you'll find most room reservations are refundable provided that you cancel before the accommodation's cancellation deadline, which is often 24 or 48 hours before your arrival date. If you have a non-refundable reservation, you might still have the option to cancel and be given a refund within a 24-hour period of your booking. Add your dates and click on "Search", then use the "fully refundable" filter to view the top deals on offer in Siesta Isle.
Where can I learn more about changing or cancelling my trip to Siesta Isle?
To access more information about picking new dates or cancelling your trip to Siesta Isle, head over to our customer service page.
What are the top things to see and do in Siesta Isle?
San Carlos Bay - Bunche Beach Preserve is an attraction you might want to check out while you're in Siesta Isle. Key West Express and Bunche Beach are also worth a visit when you're out sightseeing in Fort Myers Beach.

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