Photo by William Keller

Find hotels in Santa Lucia, Syracuse from NT$2,261

Start date: Check-in selected.
To Date
End date: Check-out

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Tonight
Nov 28 - Nov 29
Tomorrow
Nov 29 - Nov 30
This weekend
Nov 28 - Nov 30
Next weekend
Dec 5 - Dec 7

Filter by

Guest rating
Guest rating
Star rating

Discover 3,816 Santa Lucia hotels and places to stay, with room rates, reviews, and availability. Most hotels are fully refundable.

Suite | Soundproofing, free WiFi
Hotel Palazzo Cavalieri

Hotel Palazzo Cavalieri

4.0 star property
Santa Lucia
9.0 out of 10, Wonderful, (36)
"The location of this hotel is ideal! Directly between the train station and Ortigia. Easy walking to many different restaurants. We very much enjoyed our short stay here and the daily activities hosted by the Hotel. My only iffy thing was the tiles in the bathroom (the shower specifically) seemed a bit older and maybe not as cleanly as it could be, but all in all the room was quite nice. "
Canada
Lindsay
The price is NT$4,026
NT$4,590 total
includes taxes & fees
Dec 2 - Dec 3
Hotel Palazzo Cavalieri
Aerial view
Grande Albergo Alfeo

Grande Albergo Alfeo

4.0 star property
Santa Lucia
8.6 out of 10, Excellent, (650)
"The room was nice the location convenient. No view to speak of but centrally located"
Canada
Eric
Grande Albergo Alfeo
Terrace/patio
Caportigia Boutique Hotel

Caportigia Boutique Hotel

5.0 star property
Santa Lucia
9.4 out of 10, Exceptional, (253)
"Fine quality hotel with exceptional service. "
United States
Peter
The price is NT$4,266
NT$5,057 total
includes taxes & fees
Dec 4 - Dec 5
Caportigia Boutique Hotel
Double Room, 1 King Bed, Sea View, Tower | Terrace/patio
Casa Miranda Boutique

Casa Miranda Boutique

Santa Lucia
The price is NT$6,842
NT$7,890 total
includes taxes & fees
Dec 23 - Dec 24
Casa Miranda Boutique
Superior Triple Room, Sea View | Memory foam beds, in-room safe, individually furnished, desk
Fortaleza Charme House

Fortaleza Charme House

Santa Lucia
10.0 out of 10, Exceptional, (27)
"Great central location."
United States
Craig
The price is NT$4,998
NT$5,698 total
includes taxes & fees
Dec 7 - Dec 8
Fortaleza Charme House
Double or Twin Room, Balcony, Ocean View | Premium bedding, minibar, desk, soundproofing
B&B Nike

B&B Nike

Santa Lucia
8.8 out of 10, Excellent, (75)
"Clean, good location. "
United States
Salvatore
B&B Nike
Exterior
San Nicola Rooms Siracusa

San Nicola Rooms Siracusa

Santa Lucia
9.4 out of 10, Exceptional, (3)
"Stanza molto bella e nuova, ottimi arredi, letto comodo e cuscini comodi, belle tende, bagno bello e pulito, specchio del bagno fantastico con una luce bellissima regolabile a led. Mi sono trovato bene, il personale gentilissimo in particolare la ragazza (Lucia se non ricordo male) super cordiale!"
Italy
Davide Angelo
The price is NT$2,856
NT$3,256 total
includes taxes & fees
Dec 12 - Dec 13
San Nicola Rooms Siracusa
Coffee/tea maker, electric kettle
Nostos rooms & Apartments

Nostos rooms & Apartments

3.0 star property
Santa Lucia
9.0 out of 10, Wonderful, (273)
"On a main thoroughfare close to Isola di Ortigia. Friendly management and helpful to me."
United States
John
The price is NT$2,182
NT$2,487 total
includes taxes & fees
Nov 30 - Dec 1
Nostos rooms & Apartments
View from room
Hotel Mediterraneo

Hotel Mediterraneo

3.0 star property
Santa Lucia
7.8 out of 10, Good, (122)
"Very friendly and helpful staff."
United States
David
Hotel Mediterraneo
Water view
Re Dionisio Luxury Suites

Re Dionisio Luxury Suites

3.0 star property
Santa Lucia
8.8 out of 10, Excellent, (57)
"Spacious room, dated but comfortable."
United States
Kenneth
The price is NT$16,481
NT$18,493 total
includes taxes & fees
Dec 29 - Dec 30
Re Dionisio Luxury Suites
Exterior
Hotel dei Coloniali

Hotel dei Coloniali

3.0 star property
Santa Lucia
7.4 out of 10, Good, (166)
"Convenient location for Syracuse town, but in a scruffy area and the whole property is looking tired. Breakfast was adequate. The owner was charming and happy to help."
United Kingdom
Rod
The price is NT$1,983
NT$2,261 total
includes taxes & fees
Dec 14 - Dec 15
Hotel dei Coloniali
Suite, Balcony, Sea View | 1 bedroom, minibar, in-room safe, desk
Lakkios

Lakkios

3.0 star property
Santa Lucia
9.0 out of 10, Wonderful, (62)
"Nice, central, clean, easy to park, quiet during the night, staff was welcoming, nice breakfast with view - excellent choice!"
Norway
Jon-Kåre
Lakkios
Exterior
Hotel Le Muse

Hotel Le Muse

3.0 star property
Santa Lucia
7.4 out of 10, Good, (71)
"The room was great and the staff was exceptionally helpful"
United States
Henry
The price is NT$3,194
NT$3,641 total
includes taxes & fees
Dec 15 - Dec 16
Hotel Le Muse
Terrace/patio
Piccolo Hotel Casa Mia

Piccolo Hotel Casa Mia

3.0 star property
Santa Lucia
8.6 out of 10, Excellent, (373)
"The staff is extremely nice and friendly and you feel welcome. "
Canada
Florentina
Piccolo Hotel Casa Mia
Triple Room, Housekeeping, City View | Desk, laptop workspace, free WiFi
Agorà

Agorà

Santa Lucia
10.0 out of 10, Exceptional, (1)
"Carlo was great. He wanted to help in any way. The room was excellent except for Friday night music and traffic. You want to party it is near there. Would stay there again. Walkable to most places. Good restaurants near by."
United States
Bryce
The price is NT$2,618
NT$2,984 total
includes taxes & fees
Nov 29 - Nov 30
Agorà
View from room
Calafatari B&B

Calafatari B&B

3.0 star property
Santa Lucia
10.0 out of 10, Exceptional, (11)
"We had a lovely stay. Anna was very welcoming. We had a lovely large clean room and a nice modern bathroom. She went all out for breakfast. "
United States
Carl and Lina
Calafatari B&B
Terrace/patio
Populus

Populus

1.0 star property
Santa Lucia
7.8 out of 10, Good, (74)
"Just stay somewhere else, plain and simple."
United States
Thomas
The price is NT$2,570
NT$2,930 total
includes taxes & fees
Dec 2 - Dec 3
Populus
Full-size fridge, oven, stovetop, cookware/dishes/utensils
Gymnasium

Gymnasium

3.0 star property
Santa Lucia
8.8 out of 10, Excellent, (40)
"Nice kitchen area, centrally located."
United States
Richard
Gymnasium
Double Room | Premium bedding, desk, cribs/infant beds, rollaway beds
B&B Siracusa

B&B Siracusa

Santa Lucia
9.0 out of 10, Wonderful, (59)
"Good location, very modern clean accommodation."
Canada
Malcolm
The price is NT$2,480
NT$2,828 total
includes taxes & fees
Dec 11 - Dec 12
B&B Siracusa
Exterior
AmaCasa Siracusa

AmaCasa Siracusa

Santa Lucia
10.0 out of 10, Exceptional, (1)
"Siamo stati molto bene, la struttura internamente è abbastanza ammodernata e l'accesso è stato"
Italy
Alessandro
The price is NT$2,975
NT$3,391 total
includes taxes & fees
Dec 3 - Dec 4
AmaCasa Siracusa
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Where to stay in Santa Lucia

Find the best Santa Lucia areas and neighborhoods for the activities you enjoy most.
Temple of Apollo featuring a ruin and heritage elements

Ortigia

Travelers come to Ortigia for its seaside views, and you can see top attractions like Cathedral of Syracuse and Piazza del Duomo while you're in town.

Tiche

Gardens and restaurants are notable features of Tiche. You might consider a stop by Ionian Sea while you're exploring the neighborhood.

Neapolis

While visiting Neapolis, you might make a stop by sights like Roman Amphitheatre of Syracuse and Archaeological Park of Neapolis.

Acradina

You'll enjoy the churches and seaside views in Acradina. You might want to make time for a stop at Ionian Sea or Capuchin Quarry.

Grottasanta

Grottasanta is noteworthy for its historic sites, and you can make a stop at top attractions like Pista Ciclabile Siracusa and Ionian Sea.

Top Santa Lucia Hotel Reviews

Algila' Ortigia Charme Hotel

Algila' Ortigia Charme Hotel

10/10 Excellent
"Great location. Great service. Enjoy Ortigia!"
Roger 7-night trip
Posted 21 hours ago
Algila' Ortigia Charme Hotel

Explore a world of travel with Expedia

Frequently asked questions

What is Santa Lucia like?
Santa Lucia is a neighborhood that people enjoy for its interesting historical sites. Are you looking for Santa Lucia travel tips? Be sure to check out Porto Piccolo and Ionian Sea while you're in the neighborhood.
Where is the best place to stay in Santa Lucia?
Based on Expedia customer reviews, Fortaleza Charme House is the highest ranked property in Santa Lucia. This inn offers a beach bar and free WiFi. Other top choices in the neighborhood include Giuggiulena Villa and Lakkios.
How many hotels can I expect to find in Santa Lucia?
Expedia has 280 hotels and other accommodations in Santa Lucia to choose from, making this an ideal home base for exploring the greater Syracuse area.
If I need to cancel my hotel reservation in Santa Lucia, will I receive a refund?
Yes, you'll find most hotel bookings are fully refundable provided that you cancel prior to the accommodation's cancellation deadline, which is often 24 or 48 hours before your check-in date. If you booked a non-refundable reservation, you might be able to cancel it and be given a refund within 24 hours of your booking. Add your dates and click on "Search", then use the filter option "fully refundable" to get the best options available in Santa Lucia.
Where can I learn more about changing or cancelling my trip to Santa Lucia?
For more details about changing or cancelling your trip to Santa Lucia, click here.
What are the top things to see and do in Santa Lucia?
Landmarks in Santa Lucia that you won't want to miss include Syracuse Forum Ruins and Santa Lucia Bridge. Porto Piccolo and Ionian Sea are some other stops to visit in the neighborhood. A few places to visit in the area around Santa Lucia include Piazza Santa Lucia, Santa Lucia al Sepolcro Basilica, and Madonna delle Lacrime. When you're sightseeing in Syracuse, Papyrus Museum and Museo Archeologico Regionale Paolo Orsi are also worth a stop.