Find hotels in Santa Lucia, Syracuse from NT$2,450

    calendar shield illustration

    Change your mind

    Book hotels with free cancellation
    deals illustration

    Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in
    bed illustration

    Be picky

    Search almost a million properties worldwide

Check prices for these dates

Tonight
Aug 27 - Aug 28
Tomorrow
Aug 28 - Aug 29
This weekend
Aug 29 - Aug 31
Next weekend
Sep 5 - Sep 7

Filter by

Guest rating
Guest rating
Star rating

Discover 3,832 Santa Lucia hotels and places to stay, with room rates, reviews, and availability. Most hotels are fully refundable.

Our top choices for Santa Lucia hotels

Dimora Elisabetta
Porch

Dimora Elisabetta

The price is NT$3,387
NT$3,938 total
includes taxes & fees
Aug 28 - Aug 29
Dimora Elisabetta
Borgo Marino Plemmirio
Outdoor pool

Borgo Marino Plemmirio

4.0 star property
9.8 out of 10, Exceptional, (6)
"We had a great 3 night stay in Borgo Marino Plemmirio! Nice rooms with airconditioning and decent kitchen. The swimming pool is very nice with see views and even the Etna in the background! Very close to this somewhat isolated location is a fantastic little beach (Spiaggia Massolivieri). It is the nicest beach we have been to in Italy! Also the old town of Syracusa is a must-go-to."
The price is NT$4,289
NT$4,889 total
includes taxes & fees
Sep 27 - Sep 28
Borgo Marino Plemmirio
B&B Le Saline
Traditional Double Room | Terrace/patio

B&B Le Saline

3.0 star property
10.0 out of 10, Exceptional, (61)
"We enjoyed our staying at B&B Le Saline. Stefano is a wonderful and attentive host who uses his artistic talent to make your staying confortabile and appetizing. With his breakfast, one begins the day with Sicilian flavors and creativity! The location is great because is just about 10 min by car from Ortigia, and is in a quiet and safe neighborhood. "
The price is NT$4,182
NT$4,767 total
includes taxes & fees
Sep 9 - Sep 10
B&B Le Saline
B&B Nike
Double or Twin Room, Balcony, Ocean View | 1 bedroom, premium bedding, minibar, desk

B&B Nike

9.0 out of 10, Wonderful, (69)
"This is an AMAZING AND EXCEPTIONAL property! Tucked away in a residential area with just a three minute walk to the bus stop. The hotel is beautifully furnished and modern. The rooms are spacious and inviting. This boutique hotel feels like a luxury five star hotel. I definitely want to come back to Cagliari, and when I do, rest assured I will be staying at Nemo. Also breakfast on the roof top is amazing! "
B&B Nike
AmaCasa Siracusa
Exterior

AmaCasa Siracusa

10.0 out of 10, Exceptional, (1)
"Siamo stati molto bene, la struttura internamente è abbastanza ammodernata e l'accesso è stato"
The price is NT$2,911
NT$3,318 total
includes taxes & fees
Sep 10 - Sep 11
AmaCasa Siracusa
Lakkios
Suite, Balcony, Sea View | 1 bedroom, minibar, in-room safe, desk

Lakkios

3.0 star property
9.0 out of 10, Wonderful, (53)
"Nice location to where dining options and sites to see are numerous "
Lakkios
B&B Siracusa
Double Room | Premium bedding, desk, cribs/infant beds, rollaway beds

B&B Siracusa

9.0 out of 10, Wonderful, (59)
"Good location, very modern clean accommodation."
B&B Siracusa
Nostos rooms & Apartments
Coffee/tea maker, electric kettle

Nostos rooms & Apartments

3.0 star property
9.0 out of 10, Wonderful, (260)
"No complaints, clean spacious room with great location."
The price is NT$2,863
NT$3,264 total
includes taxes & fees
Sep 9 - Sep 10
Nostos rooms & Apartments
Piccolo Hotel Casa Mia
Terrace/patio

Piccolo Hotel Casa Mia

3.0 star property
8.6 out of 10, Excellent, (367)
"The location was great to explore Syracuse. Lots of surrounding restaurants to choose from too. The bed was a bit average and the television didn't work on the last night."
Piccolo Hotel Casa Mia
Giuggiulena Villa
Property entrance

Giuggiulena Villa

3.0 star property
10.0 out of 10, Exceptional, (125)
"Fantastic stay. Made to feel very welcome and what a lovely relaxing place to stay. Evening meal was exceptional. "
The price is NT$11,407
NT$13,005 total
includes taxes & fees
Sep 27 - Sep 28
Giuggiulena Villa
Fortuna Guest House
1 bedroom, Egyptian cotton sheets, premium bedding, down comforters

Fortuna Guest House

1.0 star property
9.2 out of 10, Wonderful, (16)
"It was easy to register, clean and a good location. Not to mention the free croissant in the morning!"
The price is NT$2,866
NT$3,267 total
includes taxes & fees
Aug 31 - Sep 1
Fortuna Guest House
Caportigia Boutique Hotel
Terrace/patio

Caportigia Boutique Hotel

5.0 star property
9.4 out of 10, Exceptional, (240)
"Perfect place"
The price is NT$6,307
NT$7,190 total
includes taxes & fees
Aug 28 - Aug 29
Caportigia Boutique Hotel
Isonzo Suites
Exclusive Room | 1 bedroom, in-room safe, soundproofing, iron/ironing board

Isonzo Suites

8.8 out of 10, Excellent, (3)
"."
The price is NT$3,402
NT$4,932 total
includes taxes & fees
Sep 4 - Sep 5
Isonzo Suites
Grande Albergo Alfeo
Aerial view

Grande Albergo Alfeo

4.0 star property
8.6 out of 10, Excellent, (637)
"Very close to Ortigia. Great shopping and dining options. Parking is difficult to find at night"
Grande Albergo Alfeo
Populus
Terrace/patio

Populus

1.0 star property
7.8 out of 10, Good, (73)
"Just stay somewhere else, plain and simple."
The price is NT$2,605
NT$2,970 total
includes taxes & fees
Sep 9 - Sep 10
Populus
Agorà
Triple Room, Housekeeping, City View | 1 bedroom, desk, laptop workspace, free WiFi

Agorà

The price is NT$3,001
NT$3,624 total
includes taxes & fees
Aug 28 - Aug 29
Agorà
Gymnasium
Full-size fridge, oven, stovetop, cookware/dishes/utensils

Gymnasium

3.0 star property
9.0 out of 10, Wonderful, (37)
"Great location, clean new comfortable room and kitt. "
Gymnasium
B&B Triskeles
Interior detail

B&B Triskeles

3.0 star property
8.0 out of 10, Very Good, (54)
"Excellent stay, close to everything and easy parking"
The price is NT$2,734
NT$3,117 total
includes taxes & fees
Sep 9 - Sep 10
B&B Triskeles
Fortaleza Charme House
Superior Triple Room, Sea View | 1 bedroom, memory foam beds, in-room safe, individually furnished

Fortaleza Charme House

10.0 out of 10, Exceptional, (21)
"It’s an updated facility, very comfortable stay."
The price is NT$5,018
NT$5,720 total
includes taxes & fees
Aug 30 - Aug 31
Fortaleza Charme House
Hotel Mediterraneo
View from room

Hotel Mediterraneo

3.0 star property
7.8 out of 10, Good, (121)
"Nice clean room, pleasant staff, great location."
Hotel Mediterraneo
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Where to stay in Santa Lucia

Find the best Santa Lucia areas and neighborhoods for the activities you enjoy most.
Temple of Apollo featuring a ruin and heritage elements

Ortigia

1 out of top 10 points of interest in this area

The historic heart of Syracuse is dotted with churches and atmospheric piazzas, where visitors enjoy sweeping sea views while dining at gourmet restaurants.

Acradina

You'll enjoy the churches and seaside views in Acradina. You might want to make time for a stop at Ionian Sea or Capuchin Quarry.

Grottasanta

Grottasanta is noteworthy for its historic sites, and you can make a stop at top attractions like Pista Ciclabile Siracusa and Ionian Sea.

Neapolis

While visiting Neapolis, you might make a stop by sights like Roman Amphitheatre of Syracuse and Archaeological Park of Neapolis.

Tiche

Gardens and restaurants are notable features of Tiche. You might consider a stop by Ionian Sea while you're exploring the neighborhood.

Top Santa Lucia Hotel Reviews

Explore a world of travel with Expedia

Explore a world of travel with Expedia

Frequently asked questions

What is Santa Lucia like?

Santa Lucia is a neighborhood that people enjoy for its interesting historical sites. Are you looking for Santa Lucia travel tips? Be sure to check out Porto Piccolo and Ionian Sea while you're in the neighborhood.

Where is the best place to stay in Santa Lucia?

Based on Expedia customer reviews, Caportigia Boutique Hotel is the highest ranked property in Santa Lucia. This property is a short 10-minute walk from Lungomare di Ortigia, and it offers a restaurant and free parking. Other top choices in the neighborhood include La casa di Aneupe and Nostos rooms & Apartments.

How many hotels can I expect to find in Santa Lucia?

Expedia has 269 hotels and other accommodations in Santa Lucia to choose from, making this an ideal home base for exploring the greater Syracuse area.

If I need to cancel my hotel reservation in Santa Lucia, will I receive a refund?

Yes, you'll find most hotel bookings are fully refundable provided that you cancel prior to the accommodation's cancellation deadline, which is often 24 or 48 hours before your check-in date. If you booked a non-refundable reservation, you might be able to cancel it and be given a refund within 24 hours of your booking. Add your dates and click on "Search", then use the filter option "fully refundable" to get the best options available in Santa Lucia.

Where can I learn more about changing or cancelling my trip to Santa Lucia?

For more details about changing or cancelling your trip to Santa Lucia, click here.

What are the top things to see and do in Santa Lucia?

Landmarks in Santa Lucia that you won't want to miss include Syracuse Forum Ruins and Santa Lucia Bridge. Porto Piccolo and Ionian Sea are some other stops to visit in the neighborhood. A few places to visit in the area around Santa Lucia include Piazza Santa Lucia, Santa Lucia al Sepolcro Basilica, and Madonna delle Lacrime. When you're sightseeing in Syracuse, Papyrus Museum and Museo Archeologico Regionale Paolo Orsi are also worth a stop.