Santa Lucia Vacations

Book a Hotel + Flight or Car together to unlock savings

  • Plan, book, travel with confidence

  • Better together

    Save up to NT$25,000 when you book a flight and hotel together*

  • Find the right fit

    With over 300,000 hotels worldwide, it's easy to create a perfect package

  • Rest easy

    Plan, book, and manage your trip all in one place

Where to stay in Santa Lucia

Find the best Santa Lucia areas and neighborhoods for the activities you enjoy most. Learn more about Santa Lucia
A historic waterfront with a stone bridge, illuminated buildings, and a calm water body.

Ortigia

4 out of top 10 points of interest in this area

Travelers come to Ortigia for its seaside views, and you can see top attractions like Cathedral of Syracuse and Piazza del Duomo while you're in town.

Find hotels in Ortigia

Santa Lucia Hotel Deals

Grande Albergo Alfeo

Grande Albergo Alfeo

4 out of 5
Via Nino Bixio 5 Syracuse SR
Fully refundableReserve now, pay when you stay
The price is NT$2,772 per night from Nov 21 to Nov 22
NT$2,772
NT$3,160 total
Nov 21 - Nov 22
includes taxes & fees
8.6/10 Excellent! (717 reviews)
"Beautiful and spacious room in a historic hotel. Breakfast buffet was delicious. Also a shout out to the excellent and thorough cleaning staff. We enjoyed our stay. The hotel was ideally located and we were able to walk to all the major spots in Palermo."

Reviewed on 2026/11/10

Grande Albergo Alfeo
Hotel Palazzo Cavalieri

Hotel Palazzo Cavalieri

4 out of 5
42 Via Malta Syracuse SR
Fully refundableReserve now, pay when you stay
The price is NT$2,526 per night from Nov 20 to Nov 21
NT$2,526
NT$2,879 total
Nov 20 - Nov 21
includes taxes & fees
Hotel Palazzo Cavalieri
Nostos rooms & Apartments

Nostos rooms & Apartments

3 out of 5
Corso Umberto I, 66 Syracuse SR
The price is NT$1,608 per night from Nov 18 to Nov 19
NT$1,608
NT$1,833 total
Nov 18 - Nov 19
includes taxes & fees
9/10 Wonderful! (303 reviews)
"Room is very clean，Staff is very nice，Location is the best，parking is easy"

Reviewed on 2026/11/9

Nostos rooms & Apartments
See all 3,628 properties in Santa Lucia
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

How much does a Santa Lucia vacation package cost?
Our Santa Lucia packages, which start from just , are the perfect way to save loads of cash. All you have to do is choose your preferred flights, hotels and rental cars to create your ideal escape.
How do I get a cheap travel package to Santa Lucia?
Combine your hotels and flights, throw in extras such as a rental car or activities, and save with a Santa Lucia vacation package. You won't just score big discounts on your escape — you'll have lots of choice at your fingertips too. When you book with Expedia, you can choose from more than 550 airlines and 1,000,000 hotels all over the world. Your affordable vacation begins right here, right now!
Where should I stay in Santa Lucia?
Take the hassle out of sightseeing by staying in a hotel right around the corner from Santa Lucia's iconic attractions. Cathedral of Syracuse and Temple of Apollo are two visitor favorites.
What are the top hotels in Santa Lucia?
If this will be your first time in Santa Lucia, book a room at Hotel Cavalieri or Paolanna Luxury Rooms. Both hotels offer friendly service and are popular options with many travelers.
How far in advance should I book my Santa Lucia vacation?
Smart travelers will likely want to reserve their seats early. You can normally compare international fares on Expedia up to 12 months before your flight. If you're purchasing tickets last minute, don't stress. Budget prices occasionally appear in the last weeks prior to departure.
What does an Expedia Santa Lucia travel package include?
Packages include hotels, flights and rental cars, but you can mix and match them to create your ideal Santa Lucia vacation. You can also add on some activities and experiences once you've made your booking. You're in charge! When you bundle your bookings with Expedia, you'll score discounts you won't find anywhere else.
What should I know before booking a Santa Lucia travel package?
You'll land impressive savings when you bundle your hotels, flights and rental cars into a package. Plus, booking everything in one place will make your trip planning easier. So why waste money or time? Whether you're putting together a ritzy romantic getaway or a budget family adventure, browse our package deals today.
Can I choose my airline with a Santa Lucia Expedia vacation package?
You can, and with more than 550 airlines to pick from globally, you have plenty of choice. Search the available options and find out which airline best fits your needs and budget.
If I'm not able to travel, can I cancel my Santa Lucia vacation package?
Yes, you can. We realize life doesn't always go to plan, so we're here to help if you have to make changes to your Santa Lucia vacation package. It may be possible to cancel or amend your itinerary at no cost if you've booked in the last 24 hours. Your airline, hotel or car rental company may charge you a fee if your booking was made more than 24 hours ago. Visit our Customer Service Portal for further information. Also, check your itinerary for the nitty-gritty on change fees.

Stay near popular Santa Lucia attractions

Porto Piccolo

8.8/10 (189 reviews)
Explore the waterfront in Syracuse with a trip to Porto Piccolo. Wander the seaside in this culturally rich area.
See properties
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.