Santa Lucia Vacations

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  • Plan, book, travel with confidence

  • Better together

    Save up to NT$5,067 when you book a flight and hotel together*

  • Find the right fit

    With over 300,000 hotels worldwide, it's easy to create a perfect package

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    Plan, book, and manage your trip all in one place

Where to stay in Santa Lucia

Find the best Santa Lucia areas and neighborhoods for the activities you enjoy most. Learn more about Santa Lucia
Temple of Apollo featuring a ruin and heritage elements

Ortigia

4 out of top 10 points of interest in this area
4.5/5(147 area reviews)

Travelers come to Ortigia for its seaside views, and you can see top attractions like Cathedral of Syracuse and Piazza del Duomo while you're in town.

Find hotels in Ortigia

Santa Lucia Hotel Deals

Grande Albergo Alfeo

Grande Albergo Alfeo

4 out of 5
Via Nino Bixio 5 Syracuse SR
Fully refundableReserve now, pay when you stay
8.6/10 Excellent! (654 reviews)
Good front desk staff, welcoming breakfast staff, clean room and good area for walking to attractions.

Reviewed on 2025/12/2

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Grande Albergo Alfeo
Caportigia Boutique Hotel

Caportigia Boutique Hotel

5 out of 5
Viale Montedoro 76 Syracuse SR
Fully refundableReserve now, pay when you stay
The price is NT$4,196 per night from Mar 8 to Mar 9
NT$4,196
NT$4,984 total
Mar 8 - Mar 9
includes taxes & fees
9.4/10 Exceptional! (267 reviews)
All staff were very polite and helpful. I liked they responded my questions quickly by messages. Good location to go to Ortigia, also to Neapolis. Room was spacious and very clean. We loved our stay, however we didn't feel luxurious as a five star hotel.

Reviewed on 2026/2/26

Caportigia Boutique Hotel
Hotel Palazzo Cavalieri

Hotel Palazzo Cavalieri

4 out of 5
42 Via Malta Syracuse SR
Fully refundableReserve now, pay when you stay
The price is NT$5,759 per night from Mar 16 to Mar 17
NT$5,759
NT$6,565 total
Mar 16 - Mar 17
includes taxes & fees
8.8/10 Excellent! (41 reviews)
Staff was very friendly and helpful. Loved that the front desk was open 24/7 and the location and walk ability was perfect. Room was clean and spacious. The bathroom could use some updating but all worked well and we enjoyed the provided shampoos, soaps, lotions, etc. Very impressed by the included ...

Reviewed on 2026/2/3

Hotel Palazzo Cavalieri
See all 3,731 properties in Santa Lucia
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

How much does a Santa Lucia vacation package cost?
Our Santa Lucia packages, which start from just , are the perfect way to save loads of cash. All you have to do is choose your preferred flights, hotels and rental cars to create your ideal escape.
How do I get a cheap travel package to Santa Lucia?
Combine your hotels and flights, throw in extras such as a rental car or activities, and save with a Santa Lucia vacation package. You won't just score big discounts on your escape — you'll have lots of choice at your fingertips too. When you book with Expedia, you can choose from more than 550 airlines and 1,000,000 hotels all over the world. Your affordable vacation begins right here, right now!
Where should I stay in Santa Lucia?
Take the hassle out of sightseeing by staying in a hotel right around the corner from Santa Lucia's iconic attractions. Cathedral of Syracuse and Temple of Apollo are two visitor favorites.
What are the top hotels in Santa Lucia?
If this will be your first time in Santa Lucia, book a room at Hotel Cavalieri or Paolanna Luxury Rooms. Both hotels offer friendly service and are popular options with many travelers.
How far in advance should I book my Santa Lucia vacation?
Smart travelers will likely want to reserve their seats early. You can normally compare international fares on Expedia up to 12 months before your flight. If you're purchasing tickets last minute, don't stress. Budget prices occasionally appear in the last weeks prior to departure.
What does an Expedia Santa Lucia travel package include?
Packages include hotels, flights and rental cars, but you can mix and match them to create your ideal Santa Lucia vacation. You can also add on some activities and experiences once you've made your booking. You're in charge! When you bundle your bookings with Expedia, you'll score discounts you won't find anywhere else.
What should I know before booking a Santa Lucia travel package?
You'll land impressive savings when you bundle your hotels, flights and rental cars into a package. Plus, booking everything in one place will make your trip planning easier. So why waste money or time? Whether you're putting together a ritzy romantic getaway or a budget family adventure, browse our package deals today.
Can I choose my airline with a Santa Lucia Expedia vacation package?
You can, and with more than 550 airlines to pick from globally, you have plenty of choice. Search the available options and find out which airline best fits your needs and budget.
If I'm not able to travel, can I cancel my Santa Lucia vacation package?
Yes, you can. We realize life doesn't always go to plan, so we're here to help if you have to make changes to your Santa Lucia vacation package. It may be possible to cancel or amend your itinerary at no cost if you've booked in the last 24 hours. Your airline, hotel or car rental company may charge you a fee if your booking was made more than 24 hours ago. Visit our Customer Service Portal for further information. Also, check your itinerary for the nitty-gritty on change fees.

Discover the most popular places to visit in Santa Lucia

Temple of Apollo featuring a ruin and heritage elements

Temple of Apollo

4.5/5(86 reviews)

Discover over 2,000 years of history when you visit the oldest Doric temple in Sicily.

Temple of Apollo

Greek Theatre of Syracuse

4.5/5(61 reviews)

You can learn about the history of Syracuse with a visit to Greek Theatre of Syracuse. Wander the seaside in this culturally rich area.

Greek Theatre of Syracuse

Archaeological Park of Neapolis

4.5/5(40 reviews)

You can learn about the history of Syracuse with a trip to Archaeological Park of Neapolis. Wander the seaside in this culturally rich area.

Archaeological Park of Neapolis
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.