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Find hotels in Santa Ana, Panama City from NT$1,062

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Discover 1,462 Santa Ana hotels and places to stay, with room rates, reviews, and availability. Most hotels are fully refundable.

Hotel Marparaiso

3.0 star property
7.8 out of 10, Good, (125)
"Everything was good. "
The price is NT$1,062
NT$1,169 total
includes taxes & fees
Jul 16 - Jul 17
Hotel Marparaiso

Hotel California Panama

3.0 star property
7.8 out of 10, Good, (85)
"Comfortable enough for a business stay. Clean and friendly place. "
The price is NT$1,122
NT$1,234 total
includes taxes & fees
Jul 16 - Jul 17
Hotel California Panama

Innfiniti Hotel & Suites

3.5 star property
7.0 out of 10, Good, (507)
"Hey decent hotel with a Courteous staff. However, It is a great hotel for the price. The pool was open but the restaurant and bar was closed. 3 1/2 stars"
The price is NT$1,386
NT$1,524 total
includes taxes & fees
Jul 16 - Jul 17
Innfiniti Hotel & Suites

Hostal La Cigarra

2.5 star property
7.4 out of 10, Good, (47)
"Great budget place to stay. Friendly, clean, good location. Would be happy to stay again in future."
Hostal La Cigarra

Casco View Apartments

3.0 star property
9.2 out of 10, Wonderful, (41)
"I liked the buildings quietness and modern style."
Casco View Apartments

Hotel República

2.0 star property
6.6 out of 10, (171)
"The wifi is strong enough to use for work. "
Hotel República

Room-sofa Bed Stay Rooftop Pool & Gym, A

2.0 star property
The price is NT$4,111
NT$4,522 total
includes taxes & fees
Jul 22 - Jul 23
Room-sofa Bed Stay Rooftop Pool & Gym, A

ART CASCO The Hotel

2.0 star property
6.0 out of 10, (3)
"Tranquilo"
ART CASCO The Hotel

w Charming 1BR in Santa Ana s Best Area

2.0 star property
The price is NT$2,105
NT$3,360 total
includes taxes & fees
Jul 28 - Jul 29
w Charming 1BR in Santa Ana s Best Area

Casa Quijano 06 By Wynwood House

4.0 star property
9.4 out of 10, Exceptional, (3)
"The apartment itself was very nice, very spacious, clean, newer furniture. Just know it’s on the third floor and there is no elevator. I didn’t see a sign on the building so it was a bit tricky to figure out which door to go to after being dropped off by the Uber. Email communication from property with building entry code and picture of the property was helpful. There are two balconies but all you really see is the apartment immediately in front of you, and so just know people can see you if you...
The price is NT$2,104
NT$3,278 total
includes taxes & fees
Jul 27 - Jul 28
Casa Quijano 06 By Wynwood House

La Manzana by Wynwood House

3.5 star property
6.8 out of 10, (11)
"Great hotel. Very close to Casco viejo"
The price is NT$1,266
NT$1,979 total
includes taxes & fees
Jul 16 - Jul 17
La Manzana by Wynwood House

Hotel Riazor

3.0 star property
3.8 out of 10, (10)
"Rough neighborhood "
Hotel Riazor

Arcadia Condo Suites

2.5 star property
9.2 out of 10, Wonderful, (31)
"I only stay for a night but if I ever returned to Panama, it would be here."
Arcadia Condo Suites

Crowne Plaza Panama Airport by IHG

4.0 star property
8.4 out of 10, Very Good, (2165)
"Great spot for the night, close to the airport "
The price is NT$3,249
NT$3,574 total
includes taxes & fees
Jul 17 - Jul 18
Crowne Plaza Panama Airport by IHG

Riande Aeropuerto Hotel & Casino

4.0 star property
8.4 out of 10, Very Good, (1881)
"The rooms were clean, the breakfast was delicious and having a bar and restaurant on the premises was bonus!"
The price is NT$3,688
NT$4,057 total
includes taxes & fees
Jul 16 - Jul 17
Riande Aeropuerto Hotel & Casino

Toscana Inn

3.5 star property
9.0 out of 10, Wonderful, (713)
"Clean rooms, friendly and helpful staff Close to City, outlet stores and Metro"
Toscana Inn

Victoria Hotel and Suites Panama

3.5 star property
8.2 out of 10, Very Good, (1003)
"Very nice property and the staff is really nice. "
Victoria Hotel and Suites Panama

Panama House Bed & Breakfast

2.5 star property
9.0 out of 10, Wonderful, (163)
"The accommodations offered great value for the money. We appreciated the ability to bring our golden retriever, and have a parking spot in front. The owner and her staff were very friendly and helpful. The back area of the property, featuring green parrots and a blue macaw, added ambience and fun to the experience."
The price is NT$1,207
NT$1,328 total
includes taxes & fees
Jul 16 - Jul 17
Panama House Bed & Breakfast

Residencial & Hotel Palazzo

3.0 star property
7.2 out of 10, Good, (119)
"The hotel was very clean they clean my room everyday. "
Residencial & Hotel Palazzo

Euro Hotel

3.0 star property
7.6 out of 10, Good, (579)
"Nice hotel "
Euro Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Santa Ana

Find the best Santa Ana areas and neighborhoods for the activities you enjoy most.
Casco Viejo map

Casco Viejo

Unique features of Casco Viejo include the historic sites and bars. Make a stop by Metropolitan Cathedral of Panama or Interoceanic Canal Museum while you're exploring the area.

Bella Vista map

Bella Vista

1 out of top 10 points of interest in this area

Bella Vista is highly notable for its popular shops, and you might want to visit top sights like Via Espana and Iglesia del Carmen. See more of Panama City by jumping on the metro at Iglesia del Carmen Station or Vía Argentina.

El Cangrejo map

El Cangrejo

The abundant dining options and casinos are top of the list for many visitors to El Cangrejo. A stop by Crown Casino or Luxor Towers might round out your trip.

San Francisco map

San Francisco

1 out of top 10 points of interest in this area

San Francisco is noteworthy for its restaurants, and you can make a stop at top attractions like Multiplaza Pacific Mall and Calle 50.

Punta Paitilla map

Punta Paitilla

Travelers come to Punta Paitilla for its abundant dining options, and you can see top attractions like Avenida Balboa and Multicentro Panama while you're in town.

Frequently asked questions

What's it like in Santa Ana?

Santa Ana is a neighborhood that travelers like for its seafood restaurants, shopping, and parks. Are you looking for Santa Ana travel tips? Be sure to check out Cinta Costera and Avenida Balboa while you're in the neighborhood.

Where is the best hotel for a stay in Santa Ana?

Based on Expedia customer reviews, Hotel República is the highest ranked property in Santa Ana. This hotel is a short 4-minute walk from Avenida Balboa, and it offers a rooftop terrace and free WiFi. Another top choice in the area is Hostal La Cigarra.

How many hotels can I expect to find in Santa Ana?

Expedia has 101 hotels and other accommodations in Santa Ana to choose from, making this an ideal home base for exploring the greater Panama City area.

If I need to cancel my hotel reservation in Santa Ana, will I receive a refund?

Yes! Most hotel room reservations are refundable provided that you cancel before the accommodation's cancellation deadline, which is usually within 24-48 hours of the scheduled arrival. If you have a non-refundable reservation, it might still be possible to cancel it and be given a refund within a 24-hour period of your booking. Add dates, click "Search", then use the "fully refundable" filter to get top deals in Santa Ana.

Where can I learn more about changing or cancelling my trip to Santa Ana?

To find more details about picking new dates or cancelling your trip to Santa Ana, head over to our customer service page.

What is there to do in this Panama City neighborhood?

If you're looking forward to a day of shopping in Santa Ana, consider Avenida Central or Avenida Balboa, and pick out the perfect souvenir. A visit to Cinta Costera is also worth the trip while you're discovering the neighborhood. Albrook Shopping Mall, Amador Theater, and Museum of Contemporary Art Panama are just a few of the places to visit in and around Santa Ana. When you're sightseeing in Panama City, Mi Pueblito and Iglesia de la Merced are also worth a stop.