Find Resorts & Hotels with Spas in Sanctuary, FL

Start date: Check-in selected.
To Date
End date: Check-out

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check availability on Sanctuary Resorts & Hotels with Spas

Our top choices for Sanctuary hotels with a spa

Outdoor pool, open 8:00 AM to 10:00 PM, cabanas (surcharge)
The Westin Cape Coral Resort At Marina Village

The Westin Cape Coral Resort At Marina Village

The Westin Cape Coral Resort At Marina Village
4.0 star property
Pelican
9.0 out of 10, Wonderful, (1006)
"Excellent stay over Thanksgiving holiday!"
United States
Nicole
The price is NT$4,613
NT$6,342 total
includes taxes & fees
Dec 21 - Dec 22
The Westin Cape Coral Resort At Marina Village
Couples treatment rooms, sauna, steam room, body treatments
Marriott Sanibel Harbour Resort & Spa

Marriott Sanibel Harbour Resort & Spa

Marriott Sanibel Harbour Resort & Spa
4.0 star property
Punta Rassa
8.4 out of 10, Very Good, (1007)
"This was thr best place that we have ever stayed at. "
United States
Matthew
The price is NT$6,276
NT$7,786 total
includes taxes & fees
Dec 21 - Dec 22
Marriott Sanibel Harbour Resort & Spa
Massages
Margaritaville Beach Resort Fort Myers

Margaritaville Beach Resort Fort Myers

Margaritaville Beach Resort Fort Myers
4.0 star property
Fort Myers Beach
9.0 out of 10, Wonderful, (1711)
"Great place "
United States
Debra Sue
The price is NT$6,491
NT$8,818 total
includes taxes & fees
Dec 19 - Dec 20
Margaritaville Beach Resort Fort Myers
Couples treatment rooms, body treatments, deep-tissue massages
Sundial Beach Resort & Spa

Sundial Beach Resort & Spa

Sundial Beach Resort & Spa
5.0 star property
Mid Island
8.6 out of 10, Excellent, (2584)
"wonderful family friendly and spotless resort"
United States
Mary Anne
The price is NT$11,608
NT$14,666 total
includes taxes & fees
Dec 19 - Dec 20
Sundial Beach Resort & Spa
Lobby
Tween Waters Island Resort & Spa

Tween Waters Island Resort & Spa

Tween Waters Island Resort & Spa
3.0 star property
Captiva
8.6 out of 10, Excellent, (1001)
"Stunning Beach View great Staff "
United States
Robert
The price is NT$10,047
NT$12,305 total
includes taxes & fees
Dec 21 - Dec 22
Tween Waters Island Resort & Spa
Outdoor pool, a heated pool, sun loungers
Resort Harbour Properties

Resort Harbour Properties

Resort Harbour Properties
3.5 star property
Punta Rassa
9.6 out of 10, Exceptional, (363)
"10/10 would stay there again"
United States
Kristie
Resort Harbour Properties
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Top Sanctuary Hotel Reviews

Matanzas Inn Bayside Resort and Marina

Matanzas Inn Bayside Resort and Marina

10/10 Excellent
"Will stay at your place again. Exceeded all of our expectations. Thank you Doug and Christine."
Douglas 4-night trip
Posted 2 days ago
Matanzas Inn Bayside Resort and Marina

Frequently asked questions

Looking to vacation at a spa hotel in Sanctuary?
Treat yourself to some time in a luxurious spa hotel and you won't regret it. Spa hotels are a great way to break out of your daily routine and add a layer of luxury to your vacation.
What's there to see and do in Sanctuary?
Enjoy Sanctuary with a stop at J. N. Ding Darling National Wildlife Refuge, Key West Express, and Blind Pass Beach. If you have a little extra time during your trip, you might want to check out Bowman's Beach and Captiva Beach.
What is a Sanctuary spa hotel?
Spa hotels in Sanctuary have full on-site spas offering services including massages and a selection of beauty treatments. Some also provide a selection of in-room treatments for the ultimate luxury. Spa hotels are great for rest, rejuvenation, and relaxation.

Explore a world of travel with Expedia