Find Resorts & Hotels with Spas in Sanibel, FL

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Check availability on Sanibel Resorts & Hotels with Spas

Tonight
Dec 20 - Dec 21
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Dec 21 - Dec 22
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Dec 26 - Dec 28
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Jan 2 - Jan 4

Our top choices for Sanibel hotels with a spa

Couples treatment rooms, body treatments, deep-tissue massages
Sundial Beach Resort & Spa

Sundial Beach Resort & Spa

Sundial Beach Resort & Spa
5.0 star property
Mid Island
8.6 out of 10, Excellent, (2584)
"wonderful family friendly and spotless resort"
United States
Mary Anne
The price is NT$12,186
NT$15,312 total
includes taxes & fees
Jan 7 - 2026/1/8
Sundial Beach Resort & Spa
Massages
Margaritaville Beach Resort Fort Myers

Margaritaville Beach Resort Fort Myers

Margaritaville Beach Resort Fort Myers
4.0 star property
Fort Myers Beach
9.0 out of 10, Wonderful, (1714)
"Great place "
United States
Debra Sue
The price is NT$6,505
NT$8,837 total
includes taxes & fees
Dec 21 - Dec 22
Margaritaville Beach Resort Fort Myers
Suite, 2 Bedrooms, Marina View | Egyptian cotton sheets, premium bedding, pillowtop beds, in-room safe
The Westin Cape Coral Resort At Marina Village

The Westin Cape Coral Resort At Marina Village

The Westin Cape Coral Resort At Marina Village
4.0 star property
Pelican
9.0 out of 10, Wonderful, (1004)
"Excellent stay over Thanksgiving holiday!"
United States
Nicole
The price is NT$4,617
NT$6,347 total
includes taxes & fees
Dec 21 - Dec 22
The Westin Cape Coral Resort At Marina Village
Couples treatment rooms, sauna, steam room, aromatherapy
Shangri-La Springs

Shangri-La Springs

Shangri-La Springs
2.5 star property
Bonita Springs
9.2 out of 10, Wonderful, (179)
"Very good location, property is nice, easy to get around "
United States
Rosa
Shangri-La Springs
Couples treatment rooms, sauna, steam room, body treatments
Marriott Sanibel Harbour Resort & Spa

Marriott Sanibel Harbour Resort & Spa

Marriott Sanibel Harbour Resort & Spa
4.0 star property
Punta Rassa
8.4 out of 10, Very Good, (1002)
"This was thr best place that we have ever stayed at. "
United States
Matthew
The price is NT$6,281
NT$7,792 total
includes taxes & fees
Dec 21 - Dec 22
Marriott Sanibel Harbour Resort & Spa
View from room
LaPlaya Beach & Golf Resort - A Noble House Resort

LaPlaya Beach & Golf Resort - A Noble House Resort

LaPlaya Beach & Golf Resort - A Noble House Resort
4.5 star property
Vanderbilt Beach
9.0 out of 10, Wonderful, (1003)
"All aspects of this resort were excellent!"
United States
kathleen
The price is NT$19,537
NT$23,613 total
includes taxes & fees
Jan 10 - 2026/1/11
LaPlaya Beach & Golf Resort - A Noble House Resort
Lobby
Tween Waters Island Resort & Spa

Tween Waters Island Resort & Spa

Tween Waters Island Resort & Spa
3.0 star property
Captiva
8.6 out of 10, Excellent, (1001)
"Stunning Beach View great Staff "
United States
Robert
The price is NT$10,692
NT$13,026 total
includes taxes & fees
Dec 24 - Dec 25
Tween Waters Island Resort & Spa
Body treatments, aromatherapy, hot stone massages, deep-tissue massages
Hyatt Regency Coconut Point Resort & Spa

Hyatt Regency Coconut Point Resort & Spa

Hyatt Regency Coconut Point Resort & Spa
4.5 star property
Bonita Springs
9.0 out of 10, Wonderful, (1002)
"This is a fabulous hotel in every way. The staff are outstanding especially Ursula who went out of her way to make sure we had what we needed. The hotel and it’s restaurants are wonderful. It is situated in the middle of beautiful groves with its on private island. Shopping is close by."
United States
Debra
The price is NT$14,234
NT$17,455 total
includes taxes & fees
Jan 4 - 2026/1/5
Hyatt Regency Coconut Point Resort & Spa
Couples treatment rooms, sauna, hot tub, steam room, body treatments
The Ritz-Carlton, Naples

The Ritz-Carlton, Naples

The Ritz-Carlton, Naples
5.0 star property
Pelican Bay
9.2 out of 10, Wonderful, (456)
"beautiful old world style hotel with modern amenities. Heated pools, great beach side restaurant, fabulous signature restaurant the Grille."
United States
Anthony
The price is NT$40,999
NT$47,436 total
includes taxes & fees
Jan 3 - 2026/1/4
The Ritz-Carlton, Naples
View from property
Resort Harbour Properties

Resort Harbour Properties

Resort Harbour Properties
3.5 star property
Punta Rassa
9.6 out of 10, Exceptional, (364)
"10/10 would stay there again"
United States
Kristie
Resort Harbour Properties
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Sanibel Hotel Reviews

Frequently asked questions

Looking for a spa hotel in Sanibel?
Book one of our fantastic spa hotels and pamper yourself from the moment you arrive. Travelers love the beaches in Sanibel. Hotels with spas are a great way to break out of your daily routine and add a layer of luxury to your weekend away.
What's there to see and do in Sanibel?
Enjoy Sanibel and visit Sanibel Island Northern Beach, Sanibel Island Lighthouse, and Periwinkle Way. If you have extra time while you're in the area, you might want to see Sanibel Island Southern Beach and J. N. Ding Darling National Wildlife Refuge.
What is a Sanibel spa hotel?
Spa hotels in Sanibel provide lodging and have an on-site spa which offers services like couples massages as well as body treatments. Some also offer in-room treatments. Spa hotels are a must if you want to give yourself an extra treat while on vacation.

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