Find hotels in Illinois Medical District, Chicago

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Our top choices for Illinois Medical District hotels

Hampton Inn & Suites Chicago Medical District UIC

Hampton Inn & Suites Chicago Medical District UIC
2.5 star property
Illinois Medical District
9.6 out of 10, Exceptional, (519 reviews)
"Great stay!"
United States
Jonathon
The price is NT$4,747
NT$5,573 total
includes taxes & fees
Mar 25 - Mar 26
Hampton Inn & Suites Chicago Medical District UIC

Hyatt House Chicago Medical/University District

Hyatt House Chicago Medical/University District
3.5 star property
Illinois Medical District
9.0 out of 10, Wonderful, (1,456 reviews)
"Great location and great breakfast!"
United States
Sidney
The price is NT$4,596
NT$5,396 total
includes taxes & fees
Mar 30 - Mar 31
Hyatt House Chicago Medical/University District

Hyatt Place Chicago Medical/University District

Hyatt Place Chicago Medical/University District
3.0 star property
Illinois Medical District
9.0 out of 10, Wonderful, (1,490 reviews)
"It was a nice place to stay near United Center."
United States
Jason Matthew
The price is NT$4,437
NT$5,208 total
includes taxes & fees
Apr 5 - Apr 6
Hyatt Place Chicago Medical/University District

Hyatt Place Itasca

Hyatt Place Itasca
3.0 star property
30.3 km from Illinois Medical District
8.8 out of 10, Excellent, (1,001 reviews)
"Nice room, great breakfast"
United States
Fred
The price is NT$3,096
NT$3,436 total
includes taxes & fees
Mar 29 - Mar 30
Hyatt Place Itasca

Sable at Navy Pier Chicago, Curio Collection by Hilton

Sable at Navy Pier Chicago, Curio Collection by Hilton
4.0 star property
Streeterville, 6.4 km from Illinois Medical District
9.4 out of 10, Exceptional, (2,405 reviews)
"Great spot and view, would stay again!"
United States
Kimberly
The price is NT$4,794
NT$6,715 total
includes taxes & fees
Mar 30 - Mar 31
Sable at Navy Pier Chicago, Curio Collection by Hilton

The Chicago Hotel Collection Ambassador Gold Coast

The Chicago Hotel Collection Ambassador Gold Coast
4.0 star property
Gold Coast, 5.6 km from Illinois Medical District
8.2 out of 10, Very Good, (1,318 reviews)
"Very beautiful place to stay"
United States
angie
The price is NT$4,272
NT$5,015 total
includes taxes & fees
Mar 23 - Mar 24
The Chicago Hotel Collection Ambassador Gold Coast

Sofitel Chicago Magnificent Mile

Sofitel Chicago Magnificent Mile
4.5 star property
5.1 km from Illinois Medical District
9.4 out of 10, Exceptional, (2,341 reviews)
"Very nice hotel. Great accommodations, delicious restaurant and clean. Will stay here again! Rooms are on the smaller side but enough for what we needed and it was nice to have a view from top floor! "
United States
Jon
The price is NT$6,291
NT$8,322 total
includes taxes & fees
Mar 29 - Mar 30
Sofitel Chicago Magnificent Mile

Hilton Garden Inn Chicago Downtown South Loop

Hilton Garden Inn Chicago Downtown South Loop
3.0 star property
The Loop, 4.1 km from Illinois Medical District
8.8 out of 10, Excellent, (1,923 reviews)
"Hotel was really nice"
United States
LaCarr
The price is NT$3,638
NT$4,271 total
includes taxes & fees
Apr 5 - Apr 6
Hilton Garden Inn Chicago Downtown South Loop

Hilton Chicago

Hilton Chicago
4.0 star property
The Loop, 4.2 km from Illinois Medical District
8.6 out of 10, Excellent, (2,697 reviews)
"Amazing place to stay!"
United States
Nia
The price is NT$4,162
NT$5,822 total
includes taxes & fees
Apr 1 - Apr 2
Hilton Chicago

Homewood Suites by Hilton Chicago Downtown South Loop

Homewood Suites by Hilton Chicago Downtown South Loop
3.0 star property
The Loop, 4.1 km from Illinois Medical District
8.8 out of 10, Excellent, (2,289 reviews)
"Great Hotel, location close to all attractions, clean, perfect breakfast "
United States
Sheila
The price is NT$4,291
NT$5,037 total
includes taxes & fees
Apr 5 - Apr 6
Homewood Suites by Hilton Chicago Downtown South Loop

Congress Plaza Hotel

Congress Plaza Hotel
3.5 star property
The Loop, 4.2 km from Illinois Medical District
8.0 out of 10, Very Good, (9,983 reviews)
"Great location, beautiful historic hotel with clean, updated rooms. "
United States
Jennifer
The price is NT$3,706
NT$4,350 total
includes taxes & fees
Apr 1 - Apr 2
Congress Plaza Hotel

Swissotel - Chicago

Swissotel - Chicago
4.5 star property
5 km from Illinois Medical District
9.0 out of 10, Wonderful, (3,229 reviews)
"Helpful staff, great location with views, restaurant and bar on-site"
United States
Natalie
The price is NT$4,111
NT$5,950 total
includes taxes & fees
Mar 29 - Mar 30
Swissotel - Chicago

Hotel Riu Plaza Chicago

Hotel Riu Plaza Chicago
4.0 star property
Streeterville, 5.1 km from Illinois Medical District
9.4 out of 10, Exceptional, (3,590 reviews)
"Great location ans staff was amazing!!"
United States
Bianca
The price is NT$4,393
NT$6,057 total
includes taxes & fees
Mar 29 - Mar 30
Hotel Riu Plaza Chicago

La Quinta Inn & Suites by Wyndham Chicago Downtown

La Quinta Inn & Suites by Wyndham Chicago Downtown
3.0 star property
The Loop, 3.6 km from Illinois Medical District
8.6 out of 10, Excellent, (2,729 reviews)
"Great place for the price!"
United States
Xavier
The price is NT$3,706
NT$4,912 total
includes taxes & fees
Mar 29 - Mar 30
La Quinta Inn & Suites by Wyndham Chicago Downtown

Embassy Suites by Hilton Chicago Downtown Magnificent Mile

Embassy Suites by Hilton Chicago Downtown Magnificent Mile
4.0 star property
Streeterville, 5.2 km from Illinois Medical District
8.2 out of 10, Very Good, (2,800 reviews)
"Every thing was in walking distance and the hotel is beautiful I will definitely be back "
United States
Shannon
The price is NT$3,805
NT$5,403 total
includes taxes & fees
Apr 6 - Apr 7
Embassy Suites by Hilton Chicago Downtown Magnificent Mile

Hampton Inn Chicago Downtown/Magnificent Mile

Hampton Inn Chicago Downtown/Magnificent Mile
2.5 star property
Streeterville, 5.2 km from Illinois Medical District
8.2 out of 10, Very Good, (1,396 reviews)
"Clean room great location "
United States
Karen
The price is NT$3,638
NT$4,271 total
includes taxes & fees
Mar 24 - Mar 25
Hampton Inn Chicago Downtown/Magnificent Mile

Hampton Inn Chicago West Loop Fulton Market Area

Hampton Inn Chicago West Loop Fulton Market Area
2.5 star property
3.1 km from Illinois Medical District
9.4 out of 10, Exceptional, (1,003 reviews)
"We loved the hotel, staff was friendly and area was amazing for food and is walkable to a lot of places on the west loop!"
United States
Benjamin
The price is NT$4,865
NT$5,712 total
includes taxes & fees
Apr 4 - Apr 5
Hampton Inn Chicago West Loop Fulton Market Area

L7 Chicago by LOTTE

L7 Chicago by LOTTE
4.5 star property
Theatre District, 4.5 km from Illinois Medical District
9.6 out of 10, Exceptional, (3,794 reviews)
"Amazing hotel-- Loved staying here."
United States
Maureen
The price is NT$5,429
NT$6,374 total
includes taxes & fees
Mar 24 - Mar 25
L7 Chicago by LOTTE

Omni Chicago Hotel

Omni Chicago Hotel
4.5 star property
Streeterville, 5 km from Illinois Medical District
9.2 out of 10, Wonderful, (1,713 reviews)
"Wonderful experience from check-in to check-out. The staff is great, location is perfect."
United States
Carla
The price is NT$4,820
NT$6,595 total
includes taxes & fees
Mar 25 - Mar 26
Omni Chicago Hotel

Fairmont Chicago at Millennium Park

Fairmont Chicago at Millennium Park
4.5 star property
The Loop, 4.8 km from Illinois Medical District
8.6 out of 10, Excellent, (2,089 reviews)
"Great location and nicely maintained rooms "
United States
Brianna
The price is NT$5,399
NT$7,462 total
includes taxes & fees
Mar 24 - Mar 25
Fairmont Chicago at Millennium Park
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Illinois Medical District

Find the best Illinois Medical District areas and neighborhoods for the activities you enjoy most.

Downtown Chicago

The heart of the Midwest’s glittering metropolis has many offerings, from shopping and dining to parks, museums and exciting contemporary public art.

Magnificent Mile

Upscale shopping district with luxury department stores, boutiques, and acclaimed restaurants, featuring landmarks like the Wrigley Building and Chicago Water Tower. The Magnificent Mile is easily accessible by public transit and seasonal trolley service.

The Loop

Chicago's central business district boasts numerous global businesses, retail establishments, and theaters. Explore the Loop Retail Historic District, Chicago Landmark Historic Michigan Boulevard District, and visit iconic attractions like the Art Institute of Chicago.

River North

Artistic spirit thrives here, with art galleries and a design district featuring luxury interior furnishings. Explore Kingsbury Park, enjoy vibrant nightlife on Hubbard Street, and visit the iconic Contemporaine Building.

Lincoln Park

Upscale national retailers, boutiques, and bookstores abound in this affluent area, alongside numerous restaurants and coffee shops. Must-see attractions include Lincoln Park Zoo, Chicago History Museum, and North Avenue Beach. Easily accessible via CTA transit and major roads.

Top Illinois Medical District Hotel Reviews

Frequently asked questions

What's it like in Illinois Medical District?
Guests are sure to enjoy their time checking out all that Chicago's Illinois Medical District neighborhood has to offer.
Where is the best place to stay in Illinois Medical District?
Based on Expedia customer reviews, Hampton Inn & Suites Chicago Medical District UIC is the highest ranked property in Illinois Medical District. This hotel is a short 15-minute walk from United Center, and it offers free breakfast and an indoor pool. Other top choices in the neighborhood include Hyatt House Chicago Medical/University District and Hyatt Place Chicago Medical/University District.
How many hotels are there in the Illinois Medical District area?
Expedia has 9 Illinois Medical District hotels and other accommodations, and one might make a good home base for venturing out into the greater Chicago area.
If I need to cancel my hotel reservation in Illinois Medical District, will I receive a refund?
Yes! Most hotel reservations are refundable provided that you cancel before the hotel's cancellation deadline, which often is within 24-48 hours of your arrival date. If you booked a non-refundable reservation, you might be able to still cancel and be given a refund within a 24-hour period of booking. Add dates, click "Search", then use the "fully refundable" filter to review the best options available in Illinois Medical District.
Where can I learn more about changing or cancelling my trip to Illinois Medical District?
To access more information about changing or cancelling your trip to Illinois Medical District, head over to our customer service page.
What can I see and do in this Chicago neighborhood?
Don't miss favorite places to visit in the surrounding area, such as Michigan Avenue, United Center, and Soldier Field. Malcolm X College and Michael Jordan Statue are also worth a visit when you're out sightseeing in Chicago.
How can I get around Illinois Medical District and the greater Chicago area?
Ready to get out and explore the city? Polk Station (Pink Line) is the closest metro station.

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