Find hotels in Illinois Medical District, Chicago
Change your mindBook hotels with free cancellation
Be pickySearch almost a million properties worldwide
Check prices for these dates
Our top choices for Illinois Medical District hotels
Hampton Inn & Suites Chicago Medical District UIC
Hampton Inn & Suites Chicago Medical District UICIllinois Medical District
9.6 out of 10, Exceptional, (378)
"Beautiful rooms, great breakfast and amazing customer service! "
Keana
The price is NT$2,786
NT$3,271 total
includes taxes & fees
Dec 29 - Dec 30
Hyatt House Chicago Medical/University District
Hyatt House Chicago Medical/University DistrictIllinois Medical District
9.0 out of 10, Wonderful, (1272)
"Clean room, nice staff, great location "
Kati
The price is NT$2,935
NT$3,446 total
includes taxes & fees
Dec 29 - Dec 30
Hyatt Place Chicago Medical/University District
Hyatt Place Chicago Medical/University DistrictIllinois Medical District
9.0 out of 10, Wonderful, (1428)
"We have stayed here many times. The staff are very pleasant and accommodating and the rooms are perfect.we also enjoyed a good drink and snack in the hotel bar."
Margaret
The price is NT$2,777
NT$3,260 total
includes taxes & fees
Dec 29 - Dec 30
8.0 out of 10, Very Good, (2655)
"It's an excellent place."
Jose
The price is NT$1,846
NT$2,723 total
includes taxes & fees
Jan 4 - 2026/1/5
8.6 out of 10, Excellent, (2975)
"Great place to stay"
Elisha
The price is NT$2,714
NT$3,186 total
includes taxes & fees
Jan 6 - 2026/1/7
Club Quarters Hotel Wacker at Michigan, Chicago
Club Quarters Hotel Wacker at Michigan, ChicagoThe Loop, 4.6 km from Illinois Medical District
8.8 out of 10, Excellent, (2006)
"Great stay"
Kramer
The price is NT$2,625
NT$3,081 total
includes taxes & fees
Dec 23 - Dec 24
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Where to stay in Illinois Medical District
Find the best Illinois Medical District areas and neighborhoods for the activities you enjoy most.
Downtown Chicago
The heart of the Midwest’s glittering metropolis has many offerings, from shopping and dining to parks, museums and exciting contemporary public art.
Magnificent Mile
Upscale shopping district with luxury department stores, boutiques, and acclaimed restaurants, featuring landmarks like the Wrigley Building and Chicago Water Tower. The Magnificent Mile is easily accessible by public transit and seasonal trolley service.
The Loop
Chicago's central business district boasts numerous global businesses, retail establishments, and theaters. Explore the Loop Retail Historic District, Chicago Landmark Historic Michigan Boulevard District, and visit iconic attractions like the Art Institute of Chicago.
River North
Artistic spirit thrives here, with art galleries and a design district featuring luxury interior furnishings. Explore Kingsbury Park, enjoy vibrant nightlife on Hubbard Street, and visit the iconic Contemporaine Building.
Theatre District
While you're in Theatre District, take in top sights like Michigan Avenue or State Street, and hop on the metro to see more the city at Washington Station or Monroe Station (Blue Line).
Frequently asked questions
Explore a world of travel with Expedia
- Hotels near Illinois Medical District Station
- Hotels near Monadnock Building
- La Quinta Inn & Suites Hotels in Goose Island
- Hotels with an Indoor Pool in South Loop
- Hotels with Early Check-in in Downtown Chicago
- Casino Hotels in Chicago
- Hotels near Chicago Loop Synagogue
- Hotels near Field Museum of Natural History
- Hotels near Cermak-Chinatown Station
- Winery Hotels in Chicago
- Hotels near Polish Museum of America
- Casino Hotels in The Loop
- Resorts in Chicago
- 4 Star Hotels in Magnificent Mile
- Beach Hotels in Near North Side
- Hotels with Free Parking in West Town
- Adventure Hotels in Chicago
- Wicker Park Hotels
- Gay friendly Hotels in Printers Row
- Douglas Park Hotels
- Motels in Chicago
- Hilton Hotels in Downtown Chicago
- Gay friendly Hotels in Downtown Chicago
- Hotels near Humboldt Park
- Hotels near Lollapalooza
- Gay friendly Hotels in West Loop
- Pilsen Hotels
- Hotels near Clinton Station
- Resorts in Racine Station
- Hotels near Tribune Tower
- Beach Hotels in Downtown Chicago
- Hotels with Free Parking in Chinatown
- Hotels near Chicago Station
- Condo Rentals in Chicago
- Hotels with Early Check-in in Chicago
- Pet-Friendly Hotels in South Loop
- Hotels near Chinese Consulate
- Chicago Hotels
- Omni Hotels in Chicago
- Hotels near Quincy Metro Station
- River North Hotels
- Hotels near Chicago Halsted Station
- Downtown Chicago Hotels
- B&B in Chicago Union Station
- Hotels near St Nicholas Ukrainian Catholic Cathedral
- West Loop Hotels
- Luxury Hotels in Chicago
- Hotels with an Indoor Pool in The Loop
- Fairmont Hotels in Little Village
- Romantic Hotels in East Garfield Park
- Romantic Hotels in Magnificent Mile
- Cheap Hotels in The Loop
- Hotels near Prentice Women's Hospital
- Hotels with Free Parking in Streeterville
- Magnificent Mile Hotels
- Hotels near UIC-Halsted Station
- Hotel Wedding Venues Hotels in Chicago
- Hotels near Daley Plaza
- Hotels with Bars in Chicago
- Pet-Friendly Hotels in The Loop
- Family Hotels in West Loop
- Hotels near Chicago Western Avenue Station
- Hotels with smoking rooms in Downtown Chicago
- Marriott Hotels & Resorts in Grace Abbott Homes
- Hotels with WiFi in Chicago
- Hotels near DePaul University-Loop Campus
- Hotels near Old St Patrick’s Church
- Hotels near McCormick Place
- Hotels with an Indoor Pool in Downtown Chicago
- Visit Near South Side
- Garfield Park Conservatory
- Visit United Center
- Visit Greektown
- Willis Tower
- Harold Washington Library Center
- Visit East Village
- Civic Opera House
- Visit Grace Abbott Homes
- Monadnock Building
- Visit Chicago Museum Campus
- Afrocentric Bookstore
- Buckingham Fountain
- The East Bank Club
- Visit Streeterville
- Visit East Garfield Park
- Visit Chicago
- Millennium Park
- Car rentals near Lower West Side
- Payless Rental Cars in Downtown Chicago
- Fox Rental Cars Rental Cars in Near North Side
- Avis Rental Cars in River West
- Car rentals near Streeterville
- Avis Rental Cars in Bridgeport
- Dollar Rent A Car Rental Cars in Grace Abbott Homes
- Hertz Rental Cars in Ukrainian Village
- Hertz Rental Cars in North Lawndale
- Car rentals near Printers Row
- Car rentals near Chicago
- Car rentals near The East Bank Club
- Car rentals near Cooper Dual Language Academy