Find Luxury Hotels in Florida Keys

  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
  • Be picky

    Search almost a million properties worldwide

Check availability on Florida Keys Luxury Hotels

Next weekend
In two weeks

Our top choices for Florida Keys luxury hotels

The Islands of Islamorada

The Islands of Islamorada
4.0 star property
Matecumbe
9.8 out of 10, Exceptional, (70 reviews)
"Amazing stay, can’t wait to stay there again!"
United States
Anonymous traveler
The price is NT$28,287
NT$33,557 total
includes taxes & fees
Feb 2 - Feb 3
The Islands of Islamorada

Ocean Key Resort - A Noble House Resort

Ocean Key Resort - A Noble House Resort
4.0 star property
Key West Historic District
9.2 out of 10, Wonderful, (1,004 reviews)
"Clean room and front desk very friendly."
United States
Jennifer Renee
The price is NT$18,848
NT$23,646 total
includes taxes & fees
Feb 2 - Feb 3
Ocean Key Resort - A Noble House Resort

Southernmost House

Southernmost House
4.0 star property
Old Town Key West
9.4 out of 10, Exceptional, (1,000 reviews)
"Excellent location, friendly staff, great amenities. Very happy we stayed there!"
United States
Gregory
The price is NT$20,112
NT$25,547 total
includes taxes & fees
Mar 1 - Mar 2
Southernmost House

Pier House Resort & Spa

Pier House Resort & Spa
4.0 star property
Key West Historic District
9.0 out of 10, Wonderful, (1,028 reviews)
"4th time staying, great staff, location "
United States
Jeffrey
Pier House Resort & Spa

Casa Marina Key West, Curio Collection by Hilton

Casa Marina Key West, Curio Collection by Hilton
4.0 star property
Old Town Key West
8.4 out of 10, Very Good, (520 reviews)
"Beautiful historic hotel, room was spacious, lots of amenities, friendly staff, terrific views, can walk to town. "
United States
Dallas
The price is NT$14,600
NT$18,549 total
includes taxes & fees
Feb 6 - Feb 7
Casa Marina Key West, Curio Collection by Hilton

Playa Largo Resort & Spa, Autograph Collection

Playa Largo Resort & Spa, Autograph Collection
4.5 star property
Rock Harbor
8.8 out of 10, Excellent, (1,001 reviews)
"Everything was great. Very clean and excellent location"
United States
peter
The price is NT$13,498
NT$16,920 total
includes taxes & fees
Feb 2 - Feb 3
Playa Largo Resort & Spa, Autograph Collection

Southernmost Beach Resort and Guesthouses

Southernmost Beach Resort and Guesthouses
4.0 star property
Old Town Key West
8.8 out of 10, Excellent, (3,040 reviews)
"Perfect stay and location!"
United States
Laura
The price is NT$14,617
NT$18,745 total
includes taxes & fees
Feb 2 - Feb 3
Southernmost Beach Resort and Guesthouses

Opal Key Resort & Marina, Key West

Opal Key Resort & Marina, Key West
4.0 star property
Old Town Key West
9.2 out of 10, Wonderful, (1,037 reviews)
"Great location great staff"
United States
Lori
The price is NT$15,024
NT$18,141 total
includes taxes & fees
Feb 2 - Feb 3
Opal Key Resort & Marina, Key West

La Concha Key West, Autograph Collection

La Concha Key West, Autograph Collection
4.0 star property
Key West Historic District
9.0 out of 10, Wonderful, (326 reviews)
"Nice rooms and the staff was amazing way beyond what i expected, i will definitely be back again "
United States
Joshua
The price is NT$17,086
NT$20,283 total
includes taxes & fees
Mar 1 - Mar 2
La Concha Key West, Autograph Collection

Hyatt Centric Key West Resort and Spa

Hyatt Centric Key West Resort and Spa
4.0 star property
Key West Historic District
9.0 out of 10, Wonderful, (1,002 reviews)
"Our room was clean, staff was very friendly and accommodating. The location was perfect…plan to return. "
United States
Carol
The price is NT$15,795
NT$19,949 total
includes taxes & fees
Feb 9 - Feb 10
Hyatt Centric Key West Resort and Spa
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find out more about Florida Keys

Florida Keysand its attractions for luxury travelers

In the Florida Keys, luxury travelers can indulge in a variety of high-end experiences that blend relaxation with adventure. Begin your journey in Key West, where you can visit the historic Ernest Hemingway Home and Museum, offering a glimpse into the life of the iconic author while surrounded by lush gardens. For a unique aquatic experience, charter a private yacht to explore the stunning coral reefs of the Florida Keys National Marine Sanctuary, where snorkeling and diving unveil vibrant underwater ecosystems. Gourmet dining awaits at the renowned Latitudes, perched on Sunset Key, where you can savor fresh seafood while watching the sun dip below the horizon. For those seeking relaxation, indulge in a spa day at a luxury resort like the Ocean Key Resort & Spa, where you can enjoy rejuvenating treatments with ocean views. Staying in the upscale area of Islamorada allows travelers to enjoy a slower pace with beachfront resorts like the Moorings Village, providing an intimate setting with lush tropical gardens and private beach access, perfect for families seeking both adventure and pampering. With attentive service and exquisite surroundings, the Florida Keys present a captivating escape for travelers.

Top Florida Keys Hotel Reviews