A beach with palm trees, people relaxing on chairs, and colorful kayaks.

Florida Keys 4 Stars Hotels

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Check availability on Florida Keys 4 Star Hotels

Tonight
Sep 14 - Sep 15
Tomorrow
Sep 15 - Sep 16
This weekend
Sep 18 - Sep 20
Next weekend
Sep 25 - Sep 27

Our top choices for Florida Keys 4-star hotels

1. Reefhouse Resort & Marina

Reefhouse Resort & Marina
Key Largo
United States
Susan
NT$6,930
NT$9,062 total
includes taxes & fees
Sep 15 - Sep 16
Reefhouse Resort & Marina

2. Baker's Cay Resort Key Largo, Curio Collection by Hilton

Baker's Cay Resort Key Largo, Curio Collection by Hilton
Key Largo
United States
Milagros
NT$7,499
NT$10,181 total
includes taxes & fees
Sep 28 - Sep 29
Baker's Cay Resort Key Largo, Curio Collection by Hilton

3. Amara Cay Resort

Amara Cay Resort
Matecumbe
United States
Amy
NT$4,891
NT$7,817 total
includes taxes & fees
Sep 16 - Sep 17
Amara Cay Resort

4. Three Waters Resort and Marina, Islamorada, a Tribute Portfolio Resort

Three Waters Resort and Marina, Islamorada, a Tribute Portfolio Resort
Islamorada
Canada
Eslita
NT$5,797
NT$8,836 total
includes taxes & fees
Sep 20 - Sep 21
Three Waters Resort and Marina, Islamorada, a Tribute Portfolio Resort

5. Hawks Cay Resort

Hawks Cay Resort
Marathon
United States
Clara
NT$5,870
NT$9,036 total
includes taxes & fees
Sep 20 - Sep 21
Hawks Cay Resort

6. Playa Largo Resort & Spa, Autograph Collection

Playa Largo Resort & Spa, Autograph Collection
Rock Harbor
United States
Danilo
NT$8,069
NT$10,822 total
includes taxes & fees
Sep 27 - Sep 28
Playa Largo Resort & Spa, Autograph Collection

7. Islander Resort

Islander Resort
Matecumbe
United States
Sonia
NT$7,020
NT$10,034 total
includes taxes & fees
Sep 21 - Sep 22
Islander Resort

8. Tranquility Bay Beachfront Hotel and Resort

Tranquility Bay Beachfront Hotel and Resort
Marathon
United Kingdom
Stuart
NT$6,050
NT$8,832 total
includes taxes & fees
Oct 4 - Oct 5
Tranquility Bay Beachfront Hotel and Resort

9. La Siesta Resort & Villas

La Siesta Resort & Villas
Matecumbe
United States
Brianne
La Siesta Resort & Villas

10. Faro Blanco Resort Marathon Florida Keys, Curio by Hilton

Faro Blanco Resort Marathon Florida Keys, Curio by Hilton
Marathon
United States
DANA
NT$4,645
NT$6,416 total
includes taxes & fees
Sep 20 - Sep 21
Faro Blanco Resort Marathon Florida Keys, Curio by Hilton

11. Grassy Flats Resort & Beach Club

Grassy Flats Resort & Beach Club
Marathon
United States
Tiffany
NT$5,540
NT$7,751 total
includes taxes & fees
Oct 13 - Oct 14
Grassy Flats Resort & Beach Club

12. Villas At Hawks Cay Resort

Villas At Hawks Cay Resort
Marathon
United States
Gabriela
NT$11,993
NT$15,450 total
includes taxes & fees
Sep 15 - Sep 16
Villas At Hawks Cay Resort

13. The Islands of Islamorada

The Islands of Islamorada
Matecumbe
United States
Christian
NT$12,816
NT$16,419 total
includes taxes & fees
Sep 15 - Sep 16
The Islands of Islamorada

14. Marlin Bay Resort & Marina

Marlin Bay Resort & Marina
Marathon
United States
Chardell
Marlin Bay Resort & Marina

15. Waterfront Luxury Villa

Waterfront Luxury Villa
Marathon Shores
Waterfront Luxury Villa
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Explore similar 5-star hotels

Many 5-star hotels have the same amenities as 4-star hotels. See all 5-star hotels in Florida Keys.
Cheeca Lodge & Spa

Cheeca Lodge & Spa

81801 Overseas Highway, Mile Marker 82 Islamorada FL
NT$4,715
NT$7,619 total
Sep 15 - Sep 16
includes taxes & fees
Cheeca Lodge & Spa
Isla Bella Beach Resort & Spa

Isla Bella Beach Resort & Spa

1 Knights Key Boulevard Marathon FL
NT$5,667
NT$8,240 total
Sep 15 - Sep 16
includes taxes & fees
9.2/10 Wonderful! (1,271 reviews)
Isla Bella Beach Resort & Spa
Still don't see what you're looking for?
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Learn more about Florida Keys

Snorkel crystal-clear waters teeming with colorful fish, then feast on fresh-caught lobster at a laid-back waterfront shack. Drive the scenic Overseas Highway, stopping at Key West's Ernest Hemingway Home and Dry Tortugas National Park for island adventures.

See all hotels in Florida Keys
A beach with palm trees, people relaxing on chairs, and colorful kayaks.

Top Florida Keys Hotel Reviews

Hawks Cay Resort

Hawks Cay Resort

10/10 Excellent
"Overall, such an amazing property, beautiful views, and I couldn’t ask for anything more. Anglers Ale was without a doubt our best meal. What I will come back with is the breakfast café staff was lacking and we had a couple items that Engineering team had to fix in our room. Other than those two minor things we had one of the most wonderful times ever."
Matthew 2-night trip
Posted 8 hours ago
Hawks Cay Resort
Amara Cay Resort

Amara Cay Resort

10/10 Excellent
"Beautiful lobby, nice outdoor area, room is clean, the elevator is a bit old though. Pool is very big, kids love it."
Yimin 1-night trip
Posted 14 hours ago
Amara Cay Resort
Baker's Cay Resort Key Largo, Curio Collection by Hilton

Baker's Cay Resort Key Largo, Curio Collection by Hilton

10/10 Excellent
"The hotel is very lovely and cozy, the entire staff is very friendly, and the areas and rooms are very clean; I recommend it."
juan 2-night trip
Posted 16 hours ago
Baker's Cay Resort Key Largo, Curio Collection by Hilton

Frequently asked questions

What are the best 4-star hotels in Florida Keys?
You'll discover a variety of 4-star hotels in Florida Keys, including in Key Largo. Playa Largo Resort & Spa, Autograph Collection is a customer favorite in this city that offers a tennis court and a sauna. Another stay that rates highly with travelers is Bakers Cay Resort Key Largo, Curio Collection by Hilton. Dining romance packages and private picnic options help make it their preferred choice.
How much does it cost to stay in a 4-star hotel in Florida Keys?
To find a 4-star hotel in Florida Keys that fits your budget, take advantage of Expedia's handy search filters. Take a look at the availability during your vacation dates and use our pricing filter to set your maximum rate. You can also sort your results by the most affordable retreat first.
  • Search for the lowest price from NT$7,619
What's the difference between 5-star and 4-star hotels in Florida Keys?
Offering a welcoming traveler experience and upmarket décor, 4-star hotels are an excellent option for your Florida Keys getaway. These types of accommodations generally feature loads of useful amenities that make it easy to unpack and relax — think pillowtop mattresses, pools and restaurants. Or live the high life at a 5-star hotel designed to spoil you with high-end perks and amenities. Concierge assistance, premium toiletries and fine dining are typically included at these deluxe properties.

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