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South Main 4 Stars Hotels
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Compare South Main 4 Star Hotels with updated room rates, reviews, and availability. Most hotels are fully refundable.
Our top choices for South Main 4-star hotels

Hilton Houston Plaza/Medical Center
Hilton Houston Plaza/Medical Center
8.4 out of 10, Very Good, (1546)
The price is NT$2,661
NT$3,148 total
includes taxes & fees
Sep 21 - Sep 22

DoubleTree by Hilton Hotel & Suites Houston by the Galleria
DoubleTree by Hilton Hotel & Suites Houston by the Galleria
8.2 out of 10, Very Good, (2458)
The price is NT$3,557
NT$4,191 total
includes taxes & fees
Sep 7 - Sep 8

Club Quarters Hotel Downtown, Houston
Club Quarters Hotel Downtown, Houston
8.4 out of 10, Very Good, (3661)
The price is NT$3,485
NT$4,078 total
includes taxes & fees
Sep 2 - Sep 3

DoubleTree by Hilton Hotel Houston - Greenway Plaza
DoubleTree by Hilton Hotel Houston - Greenway Plaza
8.2 out of 10, Very Good, (1127)
The price is NT$3,276
NT$3,833 total
includes taxes & fees
Sep 2 - Sep 3

Hyatt Regency Houston/Galleria
Hyatt Regency Houston/Galleria
9.0 out of 10, Wonderful, (1012)
The price is NT$3,768
NT$4,444 total
includes taxes & fees
Sep 1 - Sep 2

The Westin Galleria Houston
The Westin Galleria Houston
9.0 out of 10, Wonderful, (1002)
The price is NT$4,911
NT$6,711 total
includes taxes & fees
Sep 5 - Sep 6

The Whitehall Houston
The Whitehall Houston
8.6 out of 10, Excellent, (1696)
The price is NT$4,372
NT$5,115 total
includes taxes & fees
Sep 7 - Sep 8

Blossom Hotel Houston
Blossom Hotel Houston
9.0 out of 10, Wonderful, (3494)
The price is NT$4,867
NT$5,694 total
includes taxes & fees
Sep 29 - Sep 30
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Explore similar 5-star hotels
Many 5-star hotels have the same amenities as 4-star hotels. See all 5-star hotels in South Main.

The Post Oak Hotel at Uptown Houston
1600 West Loop South, Houston, TX
The price is NT$16,631 per night from Sep 17 to Sep 18
NT$16,631
NT$19,458 total
Sep 17 - Sep 18
includes taxes & fees
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South Main Hotels by Star Rating
Hotels in South Main Neighborhoods
Stay near popular South Main attractions
- Hotels near NRG Stadium
- Hotels near MD Anderson Cancer Center
- Hotels near George R. Brown Convention Center
- Hotels near Daikin Park
- Hotels near Toyota Center
- Hotels near Rice University
- Hotels near University of Houston
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- Hotels near Smart Financial Centre at Sugar Land
- Hotels near Sugar Land Town Square
- Hotels near Texas Southern University
- Hotels near Discovery Green
- Hotels near NRG Center
- Hotels near Houston Natural Science Museum
- Hotels near Hobby Center for the Performing Arts
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