The entrance to the Kentucky Science Center with a large circular structure in the foreground.

Find hotels in West Main Historic District, Louisville

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Our top choices for West Main Historic District hotels

1. Holiday Inn Express & Suites Louisville Downtown by IHG

Holiday Inn Express & Suites Louisville Downtown by IHG
2.5 star property
West Main Historic District
8.8 out of 10, Excellent, (1,783 reviews)
"Nice stay"
United States
Brooklyn
The price is NT$2,724
NT$3,205 total
includes taxes & fees
Sep 6 - Sep 7
Holiday Inn Express & Suites Louisville Downtown by IHG

2. Homewood Suites by Hilton Louisville Downtown, KY

Homewood Suites by Hilton Louisville Downtown, KY
3.0 star property
West Main Historic District
9.4 out of 10, Exceptional, (1,019 reviews)
"Great location. Very comfortable room & you can't beat the price."
United States
Jon
The price is NT$3,631
NT$4,273 total
includes taxes & fees
Aug 31 - Sep 1
Homewood Suites by Hilton Louisville Downtown, KY

3. Towneplace Suites By Marriott Louisville Downtown

Towneplace Suites By Marriott Louisville Downtown
3.0 star property
West Main Historic District
9.2 out of 10, Wonderful, (723 reviews)
"Great hotel"
United States
Tina
The price is NT$3,090
NT$3,636 total
includes taxes & fees
Sep 9 - Sep 10
Towneplace Suites By Marriott Louisville Downtown

4. Embassy Suites Louisville Downtown

Embassy Suites Louisville Downtown
4.0 star property
West Main Historic District
9.0 out of 10, Wonderful, (1,349 reviews)
"Great place to stay, plenty of places to eat within walking distance."
United States
Spencer
The price is NT$4,154
NT$4,887 total
includes taxes & fees
Sep 1 - Sep 2
Embassy Suites Louisville Downtown

5. Galt House Hotel Trademark Collection by Wyndham

Galt House Hotel Trademark Collection by Wyndham
4.0 star property
West Main Historic District
9.0 out of 10, Wonderful, (4,292 reviews)
"Great location!"
United States
Dina
The price is NT$4,556
NT$5,360 total
includes taxes & fees
Sep 3 - Sep 4
Galt House Hotel Trademark Collection by Wyndham

6. Omni Louisville Hotel

Omni Louisville Hotel
4.0 star property
West Main Historic District
9.4 out of 10, Exceptional, (2,093 reviews)
"Beautiful hotel, nice staff, clean environment."
United States
Jon-Michael
The price is NT$5,584
NT$6,570 total
includes taxes & fees
Aug 27 - Aug 28
Omni Louisville Hotel

7. Hyatt Regency Louisville

Hyatt Regency Louisville
4.0 star property
West Main Historic District
8.8 out of 10, Excellent, (1,014 reviews)
"Amazing hotel with great amenities and very clean"
United States
Arnetta
The price is NT$4,588
NT$5,398 total
includes taxes & fees
Sep 3 - Sep 4
Hyatt Regency Louisville

8. 21c Museum Hotel Louisville

21c Museum Hotel Louisville
4.5 star property
West Main Historic District
9.4 out of 10, Exceptional, (1,011 reviews)
"Great staff!"
United States
Candice
The price is NT$5,703
NT$6,869 total
includes taxes & fees
Sep 1 - Sep 2
21c Museum Hotel Louisville

9. Cambria Hotel Louisville Downtown-Whiskey Row

Cambria Hotel Louisville Downtown-Whiskey Row
3.0 star property
West Main Historic District
9.2 out of 10, Wonderful, (1,019 reviews)
"Room and hotel was great!"
United States
Riley
The price is NT$3,310
NT$3,894 total
includes taxes & fees
Sep 3 - Sep 4
Cambria Hotel Louisville Downtown-Whiskey Row

10. The Grady

The Grady
4.0 star property
West Main Historic District
9.4 out of 10, Exceptional, (1,010 reviews)
"We had a wonderful stay and look forward to visiting again."
United States
Conswaila
The price is NT$5,233
NT$6,157 total
includes taxes & fees
Aug 26 - Aug 27
The Grady

11. Louisville Marriott Downtown

Louisville Marriott Downtown
4.0 star property
West Main Historic District
9.0 out of 10, Wonderful, (1,000 reviews)
"Great location and very helpful staff!"
United States
Lisa
The price is NT$5,452
NT$6,415 total
includes taxes & fees
Sep 4 - Sep 5
Louisville Marriott Downtown

12. SpringHill Suites by Marriott Louisville Downtown

SpringHill Suites by Marriott Louisville Downtown
3.0 star property
West Main Historic District
8.6 out of 10, Excellent, (1,008 reviews)
"The room was wonderful, the pool was fun, breakfast was good 🙂"
United States
Brittany
The price is NT$3,223
NT$3,792 total
includes taxes & fees
Sep 3 - Sep 4
SpringHill Suites by Marriott Louisville Downtown

13. Hilton Garden Inn Louisville Downtown

Hilton Garden Inn Louisville Downtown
3.5 star property
West Main Historic District
8.4 out of 10, Very Good, (1,015 reviews)
"The ladies who assisted us checking in and out were so kind and helpful and the recommendation for brunch was really nice as well. They accommodated for our stay exceptionally well."
United States
CHASTITY
The price is NT$2,848
NT$3,350 total
includes taxes & fees
Sep 4 - Sep 5
Hilton Garden Inn Louisville Downtown

14. Fairfield Inn & Suites by Marriott Louisville Downtown

Fairfield Inn & Suites by Marriott Louisville Downtown
3.0 star property
West Main Historic District
8.4 out of 10, Very Good, (1,012 reviews)
"Its one of the best places to stay in Louisville."
United States
Myles
The price is NT$2,682
NT$3,155 total
includes taxes & fees
Aug 30 - Aug 31
Fairfield Inn & Suites by Marriott Louisville Downtown

15. Residence Inn by Marriott Louisville Downtown

Residence Inn by Marriott Louisville Downtown
3.0 star property
West Main Historic District
8.8 out of 10, Excellent, (1,010 reviews)
"Great stay!"
United States
Kooper
The price is NT$3,283
NT$3,863 total
includes taxes & fees
Aug 30 - Aug 31
Residence Inn by Marriott Louisville Downtown

16. Aloft by Marriott Louisville Downtown

Aloft by Marriott Louisville Downtown
3.0 star property
West Main Historic District
9.2 out of 10, Wonderful, (1,014 reviews)
"Great place to stay location was perfect"
United States
Angela
The price is NT$3,676
NT$4,325 total
includes taxes & fees
Sep 6 - Sep 7
Aloft by Marriott Louisville Downtown

17. Courtyard by Marriott Louisville Downtown

Courtyard by Marriott Louisville Downtown
3.0 star property
West Main Historic District
8.6 out of 10, Excellent, (1,001 reviews)
"Friendly staff great location "
United States
Sam
The price is NT$3,519
NT$4,140 total
includes taxes & fees
Aug 30 - Aug 31
Courtyard by Marriott Louisville Downtown

18. Moxy Louisville Downtown

Moxy Louisville Downtown
3.5 star property
West Main Historic District
9.2 out of 10, Wonderful, (818 reviews)
"Friendly staff great location, clean"
United States
Zacarias
The price is NT$3,313
NT$3,898 total
includes taxes & fees
Sep 6 - Sep 7
Moxy Louisville Downtown

19. Hampton Inn Louisville Downtown

Hampton Inn Louisville Downtown
2.5 star property
West Main Historic District
8.4 out of 10, Very Good, (1,008 reviews)
"The room is clean, the parking is easy and the breakfast is great!"
United States
Wen
The price is NT$2,848
NT$3,350 total
includes taxes & fees
Sep 6 - Sep 7
Hampton Inn Louisville Downtown

20. Seelbach Hilton Louisville Downtown

Seelbach Hilton Louisville Downtown
4.0 star property
West Main Historic District
8.8 out of 10, Excellent, (1,003 reviews)
"Beautiful historic building. Clean room, great staff. Bar was welcoming and relaxing."
United States
Jennifer
The price is NT$4,836
NT$5,690 total
includes taxes & fees
Sep 6 - Sep 7
Seelbach Hilton Louisville Downtown
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Compare popular hotels in West Main Historic District

Property
Property class
Guest rating
Breakfast included
Pool
Spa
Pet friendly
WiFi included
Terrace/patio
Homewood Suites by Hilton Louisville Downtown, KY
3.0 star property
9.4
Exceptional
1,019 reviews
View
Terrace/patio
Hotel Distil, Autograph Collection
4.0 star property
9.6
Exceptional
499 reviews
View
Front of property
21c Museum Hotel Louisville
4.5 star property
9.4
Exceptional
1,011 reviews
View
3 bars/lounges, cocktail bar, lobby lounge
Omni Louisville Hotel
4.0 star property
9.4
Exceptional
2,093 reviews
View
Property amenity
Towneplace Suites By Marriott Louisville Downtown
3.0 star property
9.2
Wonderful
723 reviews
View

Where to stay in West Main Historic District

Find the best West Main Historic District areas and neighborhoods for the activities you enjoy most. Learn more about West Main Historic District
Learn more about West Main Historic District

Downtown Louisville

Explore "Museum Row" in the West Main District, catch a game at Louisville Slugger Field, or stroll across the pedestrian-only Big Four Bridge. Enjoy diverse attractions, restaurants, and the Louie Link skywalk.

Fairgrounds

While visiting Fairgrounds, you might make a stop by sights like Freedom Hall and Kentucky Kingdom.

Jeffersontown

Jeffersontown is known for its abundant dining options, and you can plan a trip to Jeffersontown Commons Shopping Center and Bluegrass Indoor Karting while you're in town.

St. Matthews

Major shopping destination with the fifth-largest mall in Kentucky, Mall St. Matthews, and smaller centers along Shelbyville Road. Don't miss the historic St. Matthew's Episcopal Church and Holy Trinity.

Phoenix Hill

While Phoenix Hill isn't home to many top sights, Nulu Market Place and Louisville Slugger Field are some notable places to visit nearby.

Top West Main Historic District Hotel Reviews

Frequently asked questions

What's it like in West Main Historic District?
Travelers love the West Main Historic District neighborhood for its beautiful river views, array of dining options, and sporting events. Are you looking for West Main Historic District travel tips? Be sure to check out Frazier International History Museum and Louisville Slugger Museum while you're in the neighborhood.
Where is the best hotel for a stay in West Main Historic District?
Based on our traveler data, Galt House Hotel Trademark Collection by Wyndham is one of the top choices for your stay in West Main Historic District. This hotel is a short 4-minute walk from KFC Yum Center, and it offers a full-service spa and 4 restaurants. Other good choices for your stay in the area include Omni Louisville Hotel and Holiday Inn Express & Suites Louisville Downtown by IHG.
How many hotels will I find in the West Main Historic District area?
If you're searching for places to stay in Louisville, Expedia has something to meet your needs with 234 West Main Historic District hotels and other accommodations to choose from.
If I need to cancel my hotel reservation in West Main Historic District, will I receive a refund?
Yes! You'll find that most hotel reservations are fully refundable provided that you cancel prior to the accommodation's cancellation deadline, which in most cases is within 24 or 48 hours of the scheduled arrival. If you have a non-refundable reservation, it may still be possible to cancel it and be given a refund within 24 hours of your booking. Enter your dates, click on "Search", then use the "fully refundable" filter to get the best options available in West Main Historic District.
Where can I learn more about changing or cancelling my trip to West Main Historic District?
For more details about picking new dates or cancelling your trip to West Main Historic District, go to https://www.expedia.com/service/.
What is there to do around this Louisville neighborhood?
For cultural attractions in West Main Historic District, head to Flame Run Glass Studio and Gallery, Frazier International History Museum, and Louisville Slugger Museum. 21c Museum Hotel and Muhammad Ali Center are also a couple of places to visit in the neighborhood. Kentucky Peerless Distilling Co., Louisville Glassworks, and SAR Genealogical Research Library: NSSAR Library are just a few of the places to visit in and around West Main Historic District. While you're out sightseeing, Louisville Science Center and Kentucky Museum of Art and Craft are a couple of additional sights to visit in Louisville.

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