Find hotels in West Main Historic District, Louisville

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Our top choices for West Main Historic District hotels

Galt House Hotel Trademark Collection by Wyndham

Galt House Hotel Trademark Collection by Wyndham
4.0 star property
West Main Historic District
9.0 out of 10, Wonderful, (3895)
"Great place to stay! "
United States
Rochelle
The price is NT$4,191
NT$4,932 total
includes taxes & fees
Jan 5 - 2026/1/6
Galt House Hotel Trademark Collection by Wyndham

Holiday Inn Express & Suites Louisville Downtown by IHG

Holiday Inn Express & Suites Louisville Downtown by IHG
2.5 star property
West Main Historic District
8.8 out of 10, Excellent, (1668)
"very clean throughout, helpful staff,very nice breakfast"
United States
Wayne
The price is NT$2,578
NT$3,033 total
includes taxes & fees
Jan 11 - 2026/1/12
Holiday Inn Express & Suites Louisville Downtown by IHG

Cambria Hotel Louisville Downtown-Whiskey Row

Cambria Hotel Louisville Downtown-Whiskey Row
3.0 star property
West Main Historic District
9.4 out of 10, Exceptional, (1000)
"The staff and lobby were top tier!"
United States
Emily
The price is NT$2,993
NT$3,521 total
includes taxes & fees
Jan 18 - 2026/1/19
Cambria Hotel Louisville Downtown-Whiskey Row

Homewood Suites by Hilton Louisville Downtown, KY

Homewood Suites by Hilton Louisville Downtown, KY
3.0 star property
West Main Historic District
9.2 out of 10, Wonderful, (1002)
"The room was wonderful and the staff exceptional."
United States
Daniel
The price is NT$3,222
NT$3,791 total
includes taxes & fees
Jan 21 - 2026/1/22
Homewood Suites by Hilton Louisville Downtown, KY

Econo Lodge Louisville Downtown

Econo Lodge Louisville Downtown
2.0 star property
West Main Historic District
7.2 out of 10, Good, (1004)
"Nice hotel with a great location near Whiskey Row. This is my 3rd stay at this hotel and will definitely come back again"
United States
Nicholas
The price is NT$1,977
NT$2,326 total
includes taxes & fees
Jan 10 - 2026/1/11
Econo Lodge Louisville Downtown

Moxy Louisville Downtown

Moxy Louisville Downtown
3.5 star property
West Main Historic District
9.2 out of 10, Wonderful, (701)
"Awesome location and the staff was super friendly"
United States
Kelly
The price is NT$3,269
NT$3,846 total
includes taxes & fees
Jan 3 - 2026/1/4
Moxy Louisville Downtown

The Grady

The Grady
4.0 star property
West Main Historic District
9.4 out of 10, Exceptional, (1006)
"Such an amazing hotel...restaurant is delicious! "
United States
Craig
The price is NT$4,555
NT$5,359 total
includes taxes & fees
Jan 3 - 2026/1/4
The Grady

Hyatt Regency Louisville

Hyatt Regency Louisville
4.0 star property
West Main Historic District
8.8 out of 10, Excellent, (1001)
"Enjoyed our stay "
United States
Jedediah
The price is NT$3,992
NT$4,697 total
includes taxes & fees
Dec 28 - Dec 29
Hyatt Regency Louisville

Fairfield Inn & Suites by Marriott Louisville Downtown

Fairfield Inn & Suites by Marriott Louisville Downtown
2.5 star property
West Main Historic District
8.4 out of 10, Very Good, (1003)
"Friendly staff, clean room, breakfast was good"
United States
steven
The price is NT$2,640
NT$3,107 total
includes taxes & fees
Dec 30 - Dec 31
Fairfield Inn & Suites by Marriott Louisville Downtown

Hilton Garden Inn Louisville Downtown

Hilton Garden Inn Louisville Downtown
3.5 star property
West Main Historic District
8.4 out of 10, Very Good, (1003)
"Great stay! "
United States
THERESA
The price is NT$2,691
NT$3,166 total
includes taxes & fees
Jan 15 - 2026/1/16
Hilton Garden Inn Louisville Downtown

Courtyard Louisville Downtown

Courtyard Louisville Downtown
3.0 star property
West Main Historic District
8.6 out of 10, Excellent, (1000)
"Clean room, very easy check in/out, fantastic location. "
United States
Robert
The price is NT$3,067
NT$3,609 total
includes taxes & fees
Dec 30 - Dec 31
Courtyard Louisville Downtown

Omni Louisville Hotel

Omni Louisville Hotel
4.0 star property
West Main Historic District
9.2 out of 10, Wonderful, (1744)
"This is a beautiful hotel in a great location. Very kind staff and helpful with directions."
United States
Bonnie
The price is NT$5,256
NT$6,184 total
includes taxes & fees
Jan 1 - 2026/1/2
Omni Louisville Hotel

Hampton Inn Louisville Downtown

Hampton Inn Louisville Downtown
2.5 star property
West Main Historic District
8.4 out of 10, Very Good, (1001)
"My wife and I had a wonderful time. Walking distance to many things to do. Would stay again. "
United States
Jeff
The price is NT$2,810
NT$3,306 total
includes taxes & fees
Jan 11 - 2026/1/12
Hampton Inn Louisville Downtown

21c Museum Hotel Louisville

21c Museum Hotel Louisville
4.5 star property
West Main Historic District
9.2 out of 10, Wonderful, (1002)
"Staff was very kind, the art was fantastic, location was perfect to explore Whiskey Row, and we had a gorgeous room. Loved our time away there!"
United States
Tammy
The price is NT$4,369
NT$5,298 total
includes taxes & fees
Jan 1 - 2026/1/2
21c Museum Hotel Louisville

Seelbach Hilton Louisville Downtown

Seelbach Hilton Louisville Downtown
4.0 star property
West Main Historic District
8.6 out of 10, Excellent, (1002)
"Excellent location and a great lobby bar with a top notch bourbon selection. "
United States
vincent
The price is NT$4,432
NT$5,215 total
includes taxes & fees
Dec 29 - Dec 30
Seelbach Hilton Louisville Downtown

Aloft Louisville Downtown

Aloft Louisville Downtown
3.0 star property
West Main Historic District
9.0 out of 10, Wonderful, (1000)
"Great room and location."
Canada
Rene
The price is NT$3,277
NT$3,856 total
includes taxes & fees
Jan 11 - 2026/1/12
Aloft Louisville Downtown

Louisville Marriott Downtown

Louisville Marriott Downtown
4.0 star property
West Main Historic District
9.0 out of 10, Wonderful, (1000)
"Very nice hotel. Great stay!"
United States
Brad
The price is NT$5,271
NT$6,202 total
includes taxes & fees
Jan 18 - 2026/1/19
Louisville Marriott Downtown

Embassy Suites Louisville Downtown

Embassy Suites Louisville Downtown
4.0 star property
West Main Historic District
9.0 out of 10, Wonderful, (1125)
"Staff was courteous, hotel was beautiful and clean, and breakfast was amazing!"
United States
Shunskis
The price is NT$3,841
NT$4,519 total
includes taxes & fees
Jan 11 - 2026/1/12
Embassy Suites Louisville Downtown

Towneplace Suites By Marriott Louisville Downtown

Towneplace Suites By Marriott Louisville Downtown
3.0 star property
West Main Historic District
9.2 out of 10, Wonderful, (517)
"Accommodations were perfect. Staff excellent. Food was very good."
United States
Bennett
The price is NT$3,049
NT$3,588 total
includes taxes & fees
Jan 12 - 2026/1/13
Towneplace Suites By Marriott Louisville Downtown

SpringHill Suites by Marriott Louisville Downtown

SpringHill Suites by Marriott Louisville Downtown
3.0 star property
West Main Historic District
8.4 out of 10, Very Good, (1002)
"The staff was great and the hotel was really nice. Great place to stay."
United States
James
The price is NT$2,923
NT$3,440 total
includes taxes & fees
Dec 30 - Dec 31
SpringHill Suites by Marriott Louisville Downtown
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in West Main Historic District

Find the best West Main Historic District areas and neighborhoods for the activities you enjoy most. Learn more about West Main Historic District
Learn more about West Main Historic District

Downtown Louisville

Explore "Museum Row" in the West Main District, catch a game at Louisville Slugger Field, or stroll across the pedestrian-only Big Four Bridge. Enjoy diverse attractions, restaurants, and the Louie Link skywalk.

Jeffersontown

Jeffersontown is known for its abundant dining options, and you can plan a trip to Jeffersontown Commons Shopping Center and Bluegrass Indoor Karting while you're in town.

Fairgrounds

While visiting Fairgrounds, you might make a stop by sights like Freedom Hall and Kentucky Kingdom.

St. Matthews

Major shopping destination with the fifth-largest mall in Kentucky, Mall St. Matthews, and smaller centers along Shelbyville Road. Don't miss the historic St. Matthew's Episcopal Church and Holy Trinity.

Old Louisville

Boasting Victorian architecture and the highest concentration of stained glass windows in residential homes, Old Louisville offers a walkable neighborhood with pedestrian-only streets, diverse dining options, and attractions like Central Park and the Conrad-Caldwell House.

Top West Main Historic District Hotel Reviews

Frequently asked questions

What's it like in West Main Historic District?
Travelers love the West Main Historic District neighborhood for its beautiful river views, array of dining options, and sporting events. Are you looking for West Main Historic District travel tips? Be sure to check out Frazier International History Museum and Louisville Slugger Museum while you're in the neighborhood.
Where is the best hotel for a stay in West Main Historic District?
Based on Expedia customer reviews, The Grady is the highest ranked property in West Main Historic District. This hotel is a short 5-minute walk from Louisville Slugger Museum, and it offers a restaurant and a bar. Other top choices in the neighborhood include Omni Louisville Hotel and Hotel Distil, Autograph Collection.
How many hotels will I find in the West Main Historic District area?
If you're searching for places to stay in Louisville, Expedia has something to meet your needs with 242 West Main Historic District hotels and other accommodations to choose from.
If I need to cancel my hotel reservation in West Main Historic District, will I receive a refund?
Yes! You'll find that most hotel reservations are fully refundable provided that you cancel prior to the accommodation's cancellation deadline, which in most cases is within 24 or 48 hours of the scheduled arrival. If you have a non-refundable reservation, it may still be possible to cancel it and be given a refund within 24 hours of your booking. Enter your dates, click on "Search", then use the "fully refundable" filter to get the best options available in West Main Historic District.
Where can I learn more about changing or cancelling my trip to West Main Historic District?
For more details about picking new dates or cancelling your trip to West Main Historic District, go to https://www.expedia.com/service/.
What is there to do around this Louisville neighborhood?
For cultural attractions in West Main Historic District, head to Flame Run Glass Studio and Gallery, Frazier International History Museum, and Louisville Slugger Museum. Louisville Science Center and 21c Museum Hotel are also a couple of places to visit in the neighborhood. Kentucky Peerless Distilling Co., Louisville Glassworks, and SAR Genealogical Research Library: NSSAR Library are just a few of the places to visit in and around West Main Historic District. While you're out sightseeing, Kentucky Museum of Art and Craft and Russell District Marker are a couple of additional sights to visit in Louisville.

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