Penrose, MO
St. Louis
Popular places to visit
St. Louis Union Station
You can learn about the local history of St. Louis when you make a stop at a well-known site like St. Louis Union Station. Experience the area's great live music or attend a baseball game.
Busch Stadium
Catch an event at Busch Stadium during your trip to St. Louis. Experience the area's acclaimed theater scene or attend a baseball game.
Gateway Arch
Enjoy 360-degree views and learn about the history of St. Louis at this world-famous landmark.
Enterprise Center
Catch an event at Enterprise Center during your trip to St. Louis. Experience the area's great live music or attend a baseball game.
St. Louis Zoo
In the middle of St. Louis, meet the exotic and endangered animals that live in meticulously recreated ecosystems from all over the world.
Forest Park
Nature, history and cultural institutions come together in one of the United States’ largest urban parks, which buzzes with St. Louis’ dynamic community spirit.
Penrose Hotel Deals
Drury Plaza Hotel St. Louis at the Arch
Yes
Reviewed on 2026/3/20
Pear Tree Inn St. Louis Near Union Station
The hotel was nice and clean with good amenities of free breakfast and drinks each day. Parking was easy and free. It was super convenient and close to all the kids activities (City Museum, Arch, Zoo, etc). The blackout curtains in the room actually worked! We happened here during spring break when ...
Reviewed on 2026/3/20
Clayton Plaza Hotel & Extended Stay
Loved that there was free parking on the weekend and the breakfast was pretty good. We had minimal interactions with the staff, but it was positive and they were professional. The room itself was dated, but okay. Having a fridge and microwave was very convenient. Also, the digital shower function ...
Reviewed on 2026/3/21
21C Museum Hotel St Louis
The room decor was a little out dated and the comforter could’ve have been cleaner. There were stains on the top cover, sheet, as well as the pillow cover. The bathroom had a strange odor and the room next doors walls were paper thin.
Reviewed on 2026/3/20
Hollywood Casino & Hotel St. Louis
Hotel itself was fine. Floors in our room were a little gritty to the point where I noticed dirt accumulating in the corners and I needed to clean my feet off before putting my socks on. My biggest complaint was after paying $250 for one night, we were billed another $14 for “amenities” at check ...
Reviewed on 2026/3/12
Hyatt Regency St. Louis at The Arch
Good
Reviewed on 2026/3/21
Other neighborhoods around Penrose
Central West End
Bordering Forest Park with free cultural institutions, this St. Louis neighborhood boasts a bustling commercial district along Euclid Avenue and the world's largest mosaic collection at the Cathedral Basilica of Saint Louis.
Midtown
While you're in Midtown, take in top sights like Chaifetz Arena and jump on the metro at Grand Station to see more of the city.
The Grove
The Grove might not have many top sights, but St. Louis Science Center and Missouri Botanical Gardens and Arboretum are two attractions nearby that you can check out.
Downtown West
If you're spending some time in Downtown West, St. Louis Union Station and Enterprise Center are top sights worth seeing.
The Gate
While there might not be top attractions in The Gate, you can explore the larger area and discover places like St. Louis Union Station and Enterprise Center.
Lafayette Square
The restaurants and shopping are a few reasons travelers visit Lafayette Square. Though there aren't many top sights in the neighborhood, you can visit St. Louis Union Station and Enterprise Center, a few notable attractions nearby.
