Penrose, MO
St. Louis
Popular places to visit
St. Louis Union Station
You can learn about the local history of St. Louis when you make a stop at a well-known site like St. Louis Union Station. Experience the area's great live music or attend a baseball game.
Busch Stadium
Catch an event at Busch Stadium during your trip to St. Louis. Experience the area's acclaimed theater scene or attend a baseball game.
Gateway Arch
Enjoy 360-degree views and learn about the history of St. Louis at this world-famous landmark.
St. Louis Zoo
In the middle of St. Louis, meet the exotic and endangered animals that live in meticulously recreated ecosystems from all over the world.
Enterprise Center
Catch an event at Enterprise Center during your trip to St. Louis. Experience the area's great live music or attend a baseball game.
Forest Park
Nature, history and cultural institutions come together in one of the United States’ largest urban parks, which buzzes with St. Louis’ dynamic community spirit.
Penrose Hotel Deals
Drury Plaza Hotel St. Louis at the Arch
The breakfast food was not very good. The breakfast area was kind of dirty. There were probably a couple of hundred people going through there touching the tongs, but there was not a single hand sanitizer to be found. And this was at the height of flu season. Pretty gross.
Reviewed on 2026/3/28
Pear Tree Inn St. Louis Near Union Station
Room was clean, pool was nice and breakfast had a great variety of foods to choose.
Reviewed on 2026/3/30
Clayton Plaza Hotel & Extended Stay
The staff was lovely. My room for the most part was clean however, the housekeeping staff missed a couple of empty bottles under one of bedside tables. There was also a pill under the bench. The breakfast buffet was cold, I did not have enough time to order from their fresh breakfast options.
Reviewed on 2026/3/30
21C Museum Hotel St Louis
We never got to check in lol. At 1830 they still has no rooms clean. Large line waiting. We just canceled and left 😩
Reviewed on 2026/3/30
Hyatt Regency St. Louis at The Arch
Hotel is in a great location. The Arch is right around the corner and Busch Stadium was about 3 blocks away. Room was very spacious and the Brew House restaurant was a little pricey but very good.
Reviewed on 2026/3/30
Hollywood Casino & Hotel St. Louis
Horrible banging all night long every 30 seconds bang bang bang stayed in the same room two years ago did the same thing then I videotaped the sound showed up to them. They did nothing about it for two years.
Reviewed on 2026/3/28
Other neighborhoods around Penrose
Central West End
Bordering Forest Park with free cultural institutions, this St. Louis neighborhood boasts a bustling commercial district along Euclid Avenue and the world's largest mosaic collection at the Cathedral Basilica of Saint Louis.
Midtown
While you're in Midtown, take in top sights like Chaifetz Arena and jump on the metro at Grand Station to see more of the city.
The Grove
The Grove might not have many top sights, but St. Louis Zoo and St. Louis Science Center are two attractions nearby that you can check out.
Downtown West
If you're spending some time in Downtown West, St. Louis Union Station and Enterprise Center are top sights worth seeing.
The Gate
While there might not be top attractions in The Gate, you can explore the larger area and discover places like St. Louis Union Station and Enterprise Center.
Lafayette Square
The restaurants and shopping are a few reasons travelers visit Lafayette Square. Though there aren't many top sights in the neighborhood, you can visit St. Louis Union Station and Enterprise Center, a few notable attractions nearby.
