Penrose, MO
St. Louis
Popular places to visit
St. Louis Union Station
You can learn about the local history of St. Louis when you make a stop at a well-known site like St. Louis Union Station. Experience the area's fascinating museums or attend a baseball game.
Busch Stadium
Catch an event at Busch Stadium during your trip to St. Louis. Experience the area's great live music or attend a baseball game.
Gateway Arch
Enjoy 360-degree views and learn about the history of St. Louis at this world-famous landmark.
St. Louis Zoo
In the middle of St. Louis, meet the exotic and endangered animals that live in meticulously recreated ecosystems from all over the world.
Enterprise Center
Catch an event at Enterprise Center during your trip to St. Louis. Experience the area's fascinating museums or attend a baseball game.
Forest Park
Nature, history and cultural institutions come together in one of the United States’ largest urban parks, which buzzes with St. Louis’ dynamic community spirit.
Penrose Hotel Deals
Clayton Plaza Hotel & Extended Stay
The room was very clean, there was always someone at the front desk and each staff member I encountered was friendly. The breakfast buffet was a nice bonus. Overall 10/10.
Reviewed on 2026/4/6
Drury Plaza Hotel St. Louis at the Arch
Perfection in every way. Breakfast was amazing. The soda machine was a game changer!! Breakfast tables were always clean (cleaned in between families). From the moment I walked in, the staff was friendly, welcoming, and helpful. Our hotel room was clean. The pool and hot tub space was amazing. My ...
Reviewed on 2026/4/5
Pear Tree Inn St. Louis Near Union Station
Yes
Reviewed on 2026/4/6
21C Museum Hotel St Louis
We had a double queen room and one bed didn’t have a comforter. We checked in with 4 adults but only had 3 towels in the bathroom. On the second day we asked for a comforter for the second bed and extra towels and then never received them. Elevators are a pain in the behind also. We did love all ...
Reviewed on 2026/4/6
Hyatt Regency St. Louis at The Arch
The property was nice but dated. There were not enough outlets, sink faucet not attached, awful room spray, only 1 of 4 elevators working with a very busy hotel makes for 10+ minute waits. QR codes on the room menus did not work so it was difficult to order food or even know what was offered. Plenty ...
Reviewed on 2026/4/6
Hollywood Casino & Hotel St. Louis
Clean room and friendly staff
Reviewed on 2026/4/6
Other neighborhoods around Penrose
Central West End
Bordering Forest Park with free cultural institutions, this St. Louis neighborhood boasts a bustling commercial district along Euclid Avenue and the world's largest mosaic collection at the Cathedral Basilica of Saint Louis.
Midtown
While you're in Midtown, take in top sights like Chaifetz Arena and jump on the metro at Grand Station to see more of the city.
The Grove
The Grove might not have many top sights, but St. Louis Zoo and St. Louis Science Center are two attractions nearby that you can check out.
Downtown West
If you're spending some time in Downtown West, St. Louis Union Station and Enterprise Center are top sights worth seeing.
The Gate
While there might not be top attractions in The Gate, you can explore the larger area and discover places like St. Louis Union Station and Enterprise Center.
Lafayette Square
The restaurants and shopping are a few reasons travelers visit Lafayette Square. Though there aren't many top sights in the neighborhood, you can visit St. Louis Union Station and Enterprise Center, a few notable attractions nearby.
