Penrose, MO
St. Louis
Popular places to visit

St. Louis Union Station
You can learn about the local history of St. Louis when you make a stop at a well-known site like St. Louis Union Station. Experience the area's fascinating museums or attend a baseball game.

Busch Stadium
Catch an event at Busch Stadium during your trip to St. Louis. Experience the area's great live music or attend a baseball game.

Gateway Arch
Enjoy 360-degree views and learn about the history of St. Louis at this world-famous landmark.

Enterprise Center
Catch an event at Enterprise Center during your trip to St. Louis. Experience the area's fascinating museums or attend a baseball game.

St. Louis Zoo
In the middle of St. Louis, meet the exotic and endangered animals that live in meticulously recreated ecosystems from all over the world.

Forest Park
Nature, history and cultural institutions come together in one of the United States’ largest urban parks, which buzzes with St. Louis’ dynamic community spirit.
Penrose Hotel Deals

Clayton Plaza Hotel & Extended Stay
The breakfast was excellent and was the best we’ve ever had in a hotel. Staff were very friendly and helpful. Parking was fine and felt very safe. Staff went out of their way to accommodate any requests. The fitness center is extremely well equipped and clean. Everything was excellent, in spite of ...
Reviewed on 2026/4/12

Drury Plaza Hotel St. Louis at the Arch
Breakfast was great. Hor Devours were more like a meal than a snack. Almost no wait for elevator
Reviewed on 2026/4/11

Pear Tree Inn St. Louis Near Union Station
Pool and hot tub was very nice. My family loved the free soda and juice machines!
Reviewed on 2026/4/11

Hyatt Regency St. Louis at The Arch
Great stay
Reviewed on 2026/4/11

21C Museum Hotel St Louis
Great stay
Reviewed on 2026/4/11

Hollywood Casino & Hotel St. Louis
Everything way too expensive! No places for vending machines rooms wete ok just plain. I tjought thry would be more upgrsde being in a casino environment
Reviewed on 2026/4/9
Other neighborhoods around Penrose

Central West End
Bordering Forest Park with free cultural institutions, this St. Louis neighborhood boasts a bustling commercial district along Euclid Avenue and the world's largest mosaic collection at the Cathedral Basilica of Saint Louis.

Midtown
While you're in Midtown, take in top sights like Chaifetz Arena and jump on the metro at Grand Station to see more of the city.

The Grove
The Grove might not have many top sights, but St. Louis Zoo and St. Louis Science Center are two attractions nearby that you can check out.

Downtown West
If you're spending some time in Downtown West, St. Louis Union Station and Enterprise Center are top sights worth seeing.

The Gate
While there might not be top attractions in The Gate, you can explore the larger area and discover places like St. Louis Union Station and Enterprise Center.

Lafayette Square
The restaurants and shopping are a few reasons travelers visit Lafayette Square. Though there aren't many top sights in the neighborhood, you can visit St. Louis Union Station and Enterprise Center, a few notable attractions nearby.
