Penrose, MO
St. Louis
Popular places to visit
St. Louis Union Station
You can learn about the local history of St. Louis when you make a stop at a well-known site like St. Louis Union Station. Experience the area's fascinating museums or attend a baseball game.
Busch Stadium
Catch an event at Busch Stadium during your trip to St. Louis. Experience the area's great live music or attend a baseball game.
Gateway Arch
Enjoy 360-degree views and learn about the history of St. Louis at this world-famous landmark.
St. Louis Zoo
In the middle of St. Louis, meet the exotic and endangered animals that live in meticulously recreated ecosystems from all over the world.
Enterprise Center
Catch an event at Enterprise Center during your trip to St. Louis. Experience the area's fascinating museums or attend a baseball game.
Forest Park
Nature, history and cultural institutions come together in one of the United States’ largest urban parks, which buzzes with St. Louis’ dynamic community spirit.
Penrose Hotel Deals
Clayton Plaza Hotel & Extended Stay
I didn't get rhe room I reserved, was supposed to have a separate shower and tub, and the pillows were small for a king bed.
Reviewed on 2026/4/8
Drury Plaza Hotel St. Louis at the Arch
Served a great variety of fresh and hot breakfast items! Breakfast staff was very welcoming and friendly! Desk staff were helpful. Had a toilet issue and maintenance was there right away and friendly. Nice big pool and two hot tubs. Walking distance to many restaurants, Arch and the Dome. Definitely ...
Reviewed on 2026/4/7
Pear Tree Inn St. Louis Near Union Station
Yes
Reviewed on 2026/4/7
21C Museum Hotel St Louis
Rooms were great. Nice and clean. The aeshetics were charming and eclectic. The museum was very thought provoking and laid back. Loved the gym and pool area!!!! The staff were very nice and helpful. Would love to stay here again!!!
Reviewed on 2026/4/7
Hyatt Regency St. Louis at The Arch
Nice stay at an older downtown hotel. Was in walking distance of most attractions we were in town for. Very quiet even though there were several middle and high school girls volleyball teams in town for a tournament. Would definitely stay there again.
Reviewed on 2026/4/6
Hollywood Casino & Hotel St. Louis
I liked the place I got big suite for my wife Birthday the jets on the Jacuzzi don't work it was kind of disappointing.
Reviewed on 2026/4/7
Other neighborhoods around Penrose
Central West End
Bordering Forest Park with free cultural institutions, this St. Louis neighborhood boasts a bustling commercial district along Euclid Avenue and the world's largest mosaic collection at the Cathedral Basilica of Saint Louis.
Midtown
While you're in Midtown, take in top sights like Chaifetz Arena and jump on the metro at Grand Station to see more of the city.
The Grove
The Grove might not have many top sights, but St. Louis Zoo and St. Louis Science Center are two attractions nearby that you can check out.
Downtown West
If you're spending some time in Downtown West, St. Louis Union Station and Enterprise Center are top sights worth seeing.
The Gate
While there might not be top attractions in The Gate, you can explore the larger area and discover places like St. Louis Union Station and Enterprise Center.
Lafayette Square
The restaurants and shopping are a few reasons travelers visit Lafayette Square. Though there aren't many top sights in the neighborhood, you can visit St. Louis Union Station and Enterprise Center, a few notable attractions nearby.
