Penrose, MO

St. Louis


Popular places to visit


Penrose Hotel Deals

Clayton Plaza Hotel & Extended Stay

Clayton Plaza Hotel & Extended Stay

3.5 out of 5
7750 Carondelet Avenue St. Louis MO
The price is NT$3,333 per night from Mar 22 to Mar 23
NT$3,333
NT$3,891 total
Mar 22 - Mar 23
includes taxes & fees
Book a stay at this business-friendly hotel in St. Louis. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast and ...
8.8/10 Excellent! (3,123 reviews)
The water pressure in our room's shower was the worst I've ever experienced.

Reviewed on 2026/3/9

Clayton Plaza Hotel & Extended Stay
21C Museum Hotel St Louis

21C Museum Hotel St Louis

4.5 out of 5
1528 Locust street St. Louis MO
The price is NT$4,012 per night from Apr 5 to Apr 6
NT$4,012
NT$4,850 total
Apr 5 - Apr 6
includes taxes & fees
Book a stay at this luxury hotel in St. Louis. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the pool and the restaurant in our ...
9/10 Wonderful! (1,647 reviews)
So fun and eclectic! !

Reviewed on 2026/3/10

21C Museum Hotel St Louis
Drury Plaza Hotel St. Louis at the Arch

Drury Plaza Hotel St. Louis at the Arch

3 out of 5
2 South 4th Street St. Louis MO
The price is NT$4,277 per night from Mar 15 to Mar 16
NT$4,277
NT$5,001 total
Mar 15 - Mar 16
includes taxes & fees
Book a stay at this business-friendly hotel in St. Louis. Enjoy free breakfast, free WiFi, and 2 hot tubs. Our guests praise the breakfast and the pool in our ...
9.4/10 Exceptional! (3,360 reviews)
National park near, friendlty & welcoming staff, great accommodations, wonderful food & cheers, all star view from 8th floor balcony

Reviewed on 2026/3/9

Drury Plaza Hotel St. Louis at the Arch
Hyatt Regency St. Louis at The Arch

Hyatt Regency St. Louis at The Arch

4 out of 5
315 Chestnut St St. Louis MO
The price is NT$5,354 per night from Mar 23 to Mar 24
NT$5,354
NT$6,314 total
Mar 23 - Mar 24
includes taxes & fees
Book a stay at this business-friendly hotel in St. Louis. Enjoy free WiFi, 3 restaurants, and 2 bars/lounges. Our guests praise the helpful staff and the clean ...
8.6/10 Excellent! (4,011 reviews)
We had a great experience! The hotel was beautiful, the staff were friendly and helpful and we got an upgraded room that made all the difference - a bigger bathroom for 3 girls! The location was ideal, right by the Arch and the view was spectacular. I also want to call out the staff that did the ...

Reviewed on 2026/3/9

Hyatt Regency St. Louis at The Arch
Hollywood Casino & Hotel St. Louis

Hollywood Casino & Hotel St. Louis

3.5 out of 5
777 Casino Center Drive Maryland Heights MO
The price is NT$2,982 per night from Apr 1 to Apr 2
NT$2,982
NT$3,941 total
Apr 1 - Apr 2
includes taxes & fees
Book a stay at this business-friendly hotel in Maryland Heights. Enjoy free parking, 7 restaurants, and a casino. Our guests praise the helpful staff and the ...
8.4/10 Very Good! (2,217 reviews)
The room was very clean, staff were friendly, casino was a lot of fun!!! Great place to stay for the weekend or if you are passing through!

Reviewed on 2026/2/22

Hollywood Casino & Hotel St. Louis
River City Casino & Hotel

River City Casino & Hotel

4 out of 5
777 River City Casino Blvd St. Louis MO
The price is NT$3,041 per night from Mar 11 to Mar 12
NT$3,041
NT$4,001 total
Mar 11 - Mar 12
includes taxes & fees
Book a stay at this business-friendly hotel in St. Louis. Enjoy free parking, 5 restaurants, and a casino. Our guests praise the helpful staff and the clean ...
9/10 Wonderful! (1,498 reviews)
The staff were very friendly and efficient. Check in was a breeze.

Reviewed on 2026/3/8

River City Casino & Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Other neighborhoods around Penrose

Central West End

Central West End

4.5/5(450 area reviews)

Bordering Forest Park with free cultural institutions, this St. Louis neighborhood boasts a bustling commercial district along Euclid Avenue and the world's largest mosaic collection at the Cathedral Basilica of Saint Louis.

Central West End
St. Louis, Missouri - 08.22.2021 - Brookings Hall on the Danforth Campus of Washington University in St. Louis.

Midtown

While you're in Midtown, take in top sights like Chaifetz Arena and jump on the metro at Grand Station to see more of the city.

Midtown
Not just bars but also loft apartments are lit in rainbow lights for Pride weekend in the Grove neighborhood in St. Louis! #LifeAtExpedia

The Grove

The Grove might not have many top sights, but St. Louis Science Center and Missouri Botanical Gardens and Arboretum are two attractions nearby that you can check out.

The Grove
Love this hotel.

Downtown West

If you're spending some time in Downtown West, St. Louis Union Station and St. Louis Aquarium at Union Station are top sights worth seeing.

Downtown West
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The Gate

While there might not be top attractions in The Gate, you can explore the larger area and discover places like St. Louis Union Station and Busch Stadium.

The Gate
Lafayette Square which includes a house and a garden

Lafayette Square

The restaurants and shopping are a few reasons travelers visit Lafayette Square. Though there aren't many top sights in the neighborhood, you can visit St. Louis Union Station and Busch Stadium, a few notable attractions nearby.

Lafayette Square


Penrose, MO