Penrose, MO
St. Louis
Popular places to visit

St. Louis Union Station
You can learn about the local history of St. Louis when you make a stop at a well-known site like St. Louis Union Station. Experience the area's great live music or attend a baseball game.

Busch Stadium
Catch an event at Busch Stadium during your trip to St. Louis. Experience the area's acclaimed theater scene or attend a baseball game.

Gateway Arch
Enjoy 360-degree views and learn about the history of St. Louis at this world-famous landmark.

Enterprise Center
Catch an event at Enterprise Center during your trip to St. Louis. Experience the area's great live music or attend a baseball game.

Forest Park
Nature, history and cultural institutions come together in one of the United States’ largest urban parks, which buzzes with St. Louis’ dynamic community spirit.

St. Louis Zoo
In the middle of St. Louis, meet the exotic and endangered animals that live in meticulously recreated ecosystems from all over the world.
Penrose Hotel Deals

Clayton Plaza Hotel & Extended Stay
The water pressure in our room's shower was the worst I've ever experienced.
Reviewed on 2026/3/9

21C Museum Hotel St Louis
So fun and eclectic! !
Reviewed on 2026/3/10

Drury Plaza Hotel St. Louis at the Arch
National park near, friendlty & welcoming staff, great accommodations, wonderful food & cheers, all star view from 8th floor balcony
Reviewed on 2026/3/9

Hyatt Regency St. Louis at The Arch
We had a great experience! The hotel was beautiful, the staff were friendly and helpful and we got an upgraded room that made all the difference - a bigger bathroom for 3 girls! The location was ideal, right by the Arch and the view was spectacular. I also want to call out the staff that did the ...
Reviewed on 2026/3/9

Hollywood Casino & Hotel St. Louis
The room was very clean, staff were friendly, casino was a lot of fun!!! Great place to stay for the weekend or if you are passing through!
Reviewed on 2026/2/22

River City Casino & Hotel
The staff were very friendly and efficient. Check in was a breeze.
Reviewed on 2026/3/8
Other neighborhoods around Penrose

Central West End
Bordering Forest Park with free cultural institutions, this St. Louis neighborhood boasts a bustling commercial district along Euclid Avenue and the world's largest mosaic collection at the Cathedral Basilica of Saint Louis.

Midtown
While you're in Midtown, take in top sights like Chaifetz Arena and jump on the metro at Grand Station to see more of the city.

The Grove
The Grove might not have many top sights, but St. Louis Science Center and Missouri Botanical Gardens and Arboretum are two attractions nearby that you can check out.

Downtown West
If you're spending some time in Downtown West, St. Louis Union Station and St. Louis Aquarium at Union Station are top sights worth seeing.

The Gate
While there might not be top attractions in The Gate, you can explore the larger area and discover places like St. Louis Union Station and Busch Stadium.

Lafayette Square
The restaurants and shopping are a few reasons travelers visit Lafayette Square. Though there aren't many top sights in the neighborhood, you can visit St. Louis Union Station and Busch Stadium, a few notable attractions nearby.
