Top Santa Lucia Hotels

A bridge over a turquoise waterfront with boats docked, surrounded by historic buildings.

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Where to stay in Santa Lucia

Find the best Santa Lucia areas and neighborhoods for the activities you enjoy most.

A historic waterfront with a stone bridge, illuminated buildings, and a calm water body.

Ortigia

Travelers come to Ortigia for its seaside views, and you can see top attractions like Cathedral of Syracuse and Piazza del Duomo while you're in town.

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Ancient ruins with a large amphitheater surrounded by trees.

Neapolis

While visiting Neapolis, you might make a stop by sights like Roman Amphitheatre of Syracuse and Archaeological Park of Neapolis.

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An aerial view of a coastal city with a prominent fortified structure and a densely built urban area in the background.

Grottasanta

Grottasanta is noteworthy for its historic sites, and you can make a stop at top attractions like Pista Ciclabile Siracusa and Ionian Sea.

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An ancient amphitheater with stone ruins and a grassy field.

Tiche

Gardens and restaurants are notable features of Tiche. You might consider a stop by Ionian Sea while you're exploring the neighborhood.

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Acradina

You'll enjoy the churches and seaside views in Acradina. You might want to make time for a stop at Ionian Sea or Capuchin Quarry.

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Top Santa Lucia Hotel Reviews

Algila' Ortigia Charme Hotel

10/10 Excellent

"Awesome staff Very clean, great breakfast"

Grand Hotel Ortigia Siracusa

10/10 Excellent

"I enjoyed four unforgettable days exploring beautiful Ortigia -staying at the Grand Hotel Ortigia, which is a 5-star luxury hotel overlooking the harbor. It is just a short stroll to the must-see landmarks such as the ruins of the Temple of Apollo, the Aretusa Fountain, and the renowned Cathedral of Syracuse. it was built in 1890 and was completely renovated while preserving its classic old-world charm with marble floors, Corinthian columns, and beautiful art-filled common areas. They have an upscale rooftop restaurant and lounge on the third floor, which serves a sumptuous breakfast buffet and has great outdoor seating with spectacular views. I went up to the terrace one evening to enjoy the sunset with an Aperol Spritz and some nibbles and, after the sun went down, an exceptionally talented young man beautifully played his violin serenading the guests. Parking in the old city is a challenge, and not for the faint of heart. But the hotel does have a small lot nearby, but which seemed to stay full and was hard to find. With the helpful staff, I was able to register my rental car to allow me to drive to hotel which is in the restricted tourist zone and I moved my car to their lot one evening once the crowds had dissipated a bit. The staff couldn’t have been more helpful and even helped arrange a small group boat tour. This hotel truly deserves its name the Grand Hotel Ortigia Siracusa!"

Mangia's Brucoli, Sicily, Autograph Collection

10/10 Excellent

"Staying will be an extremely fond memory for my wife and I. After the first night, we both decided to make our stay here our official honeymoon. The view from our room allowed for an incredible view of Mt Etna. The staff is professional and polite and very friendly. The breakfast buffet is pretty outstanding with so many options. Unfortunately, we didn’t get to try the other restaurants but we were able to take advantage of the Lime Bar before leaving. They absolutely captured Sicily’s beautiful culture and atmosphere. We absolutely recommend staying at Mangia, hands down, with zero hesitation."

Grand Hotel Villa Politi

8/10 Good

"Overall, we had a good stay at Grand Hotel Villa Politi. The hotel has a beautiful historic character and was very clean. The breakfast was excellent, with a wide variety of both continental and traditional Italian options. The swimming pool was another great highlight. Its location was very convenient for travelling by car, just outside the ZTL, with on-site parking available. However, the hotel has quite a lot of stairs, which can make getting around less convenient, and we found the staff could have been more helpful and attentive. Overall, a good option for exploring Syracuse, especially for travellers arriving by car."

Frequently asked questions

What is Santa Lucia like?

Santa Lucia is a neighborhood that people enjoy for its interesting historical sites. Are you looking for Santa Lucia travel tips? Be sure to check out Porto Piccolo and Ionian Sea while you're in the neighborhood.

Where is the best place to stay in Santa Lucia?

Based on our traveler data, Grande Albergo Alfeo is one of the top choices for your stay in Santa Lucia. This hotel offers free breakfast and a restaurant. Other good choices for your stay in the area include Nostos rooms & Apartments and Caportigia Boutique Hotel.

How many hotels can I expect to find in Santa Lucia?

Expedia has 313 hotels and other accommodations in Santa Lucia to choose from, making this an ideal home base for exploring the greater Syracuse area.

If I need to cancel my hotel reservation in Santa Lucia, will I receive a refund?

Yes, you'll find most hotel bookings are fully refundable provided that you cancel prior to the accommodation's cancellation deadline, which is often 24 or 48 hours before your check-in date. If you booked a non-refundable reservation, you might be able to cancel it and be given a refund within 24 hours of your booking. Add your dates and click on "Search", then use the filter option "fully refundable" to get the best options available in Santa Lucia.

Where can I learn more about changing or cancelling my trip to Santa Lucia?

For more details about changing or cancelling your trip to Santa Lucia, click here.

What are the top things to see and do in Santa Lucia?

Landmarks in Santa Lucia that you won't want to miss include Syracuse Forum Ruins and Santa Lucia Bridge. Porto Piccolo and Ionian Sea are some other stops to visit in the neighborhood. A few places to visit in the area around Santa Lucia include Piazza Santa Lucia, Santa Lucia al Sepolcro Basilica, and Madonna delle Lacrime. When you're sightseeing in Syracuse, Papyrus Museum and Museo Archeologico Regionale Paolo Orsi are also worth a stop.

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Our top choices for Santa Lucia hotels

1. Grande Albergo Alfeo

2. Caportigia Boutique Hotel

3. Nostos rooms & Apartments

4. Hotel Palazzo Cavalieri

5. Fortaleza Charme House

6. Lakkios

7. Giuggiulena Villa

8. Casa Miranda Boutique

9. Melody rooms

10. B&B Nike

11. Piccolo Hotel Casa Mia

12. San Nicola Rooms Siracusa

13. Calafatari B&B

14. Regina Margherita

15. Syraka Design Rooms & Suites

16. Gymnasium

17. B&B IL MORO

18. Residence Agatocle

19. Re Dionisio Luxury Suites

20. B&B Siracusa

Where to stay in Santa Lucia

Ortigia

Neapolis

Grottasanta

Tiche

Acradina

Top Santa Lucia Hotel Reviews

Algila' Ortigia Charme Hotel

Frequently asked questions

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