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Our top choices for Santa Lucia hotels

Calafatari B&B

Calafatari B&B
3.0 star property
Santa Lucia
10.0 out of 10, Exceptional, (12 reviews)
"Clean, very convenient for exploring Ortigia. Nice continental breakfast."
United States
Mary
The price is NT$5,563
NT$6,342 total
includes taxes & fees
Jun 10 - Jun 11
Calafatari B&B

Isonzo Suites

Isonzo Suites
Santa Lucia
8.8 out of 10, Excellent, (6 reviews)
"."
Italy
Gianluca
The price is NT$3,290
NT$4,842 total
includes taxes & fees
Jun 10 - Jun 11
Isonzo Suites

Nostos rooms & Apartments

Nostos rooms & Apartments
3.0 star property
Santa Lucia
9.0 out of 10, Wonderful, (278 reviews)
"Mario was amazing as a host. The location is amazing. I would recommend this property 100%"
United States
Michael
The price is NT$3,275
NT$3,733 total
includes taxes & fees
Jun 9 - Jun 10
Nostos rooms & Apartments

Melody rooms

Melody rooms
Santa Lucia
The price is NT$1,988
NT$2,266 total
includes taxes & fees
May 28 - May 29
Melody rooms

Caportigia Boutique Hotel

Caportigia Boutique Hotel
5.0 star property
Santa Lucia
9.4 out of 10, Exceptional, (276 reviews)
"Good location, clean room, very nice staff. "
Ireland
Borna
The price is NT$8,131
NT$9,312 total
includes taxes & fees
May 28 - May 29
Caportigia Boutique Hotel

B&B L'INFIORESCENZA

B&B L'INFIORESCENZA
Santa Lucia
10.0 out of 10, Exceptional, (1 review)
"Ho soggiornato qui con 6 amici in un appartamento interno: lenzuola pulite, personale gentilissimo e colazione inclusa al bar della struttura. Arredamento colorato e molto particolare. Ottima posizione, vicinissima al Santuario di Santa Lucia al Sepolcro. Consigliato per chi cerca una soluzione comoda e senza troppe pretese."
Italy
Antonio
The price is NT$1,092
NT$1,664 total
includes taxes & fees
Jun 8 - Jun 9
B&B L'INFIORESCENZA

AmaCasa Siracusa

AmaCasa Siracusa
Santa Lucia
10.0 out of 10, Exceptional, (1 review)
"Siamo stati molto bene, la struttura internamente è abbastanza ammodernata e l'accesso è stato"
Italy
Alessandro
The price is NT$3,011
NT$3,433 total
includes taxes & fees
Jun 8 - Jun 9
AmaCasa Siracusa

B&B Nike

B&B Nike
Santa Lucia
8.8 out of 10, Excellent, (80 reviews)
"Clean, good location. "
United States
Salvatore
The price is NT$2,325
NT$2,650 total
includes taxes & fees
May 25 - May 26
B&B Nike

Lakkios

Lakkios
3.0 star property
Santa Lucia
9.0 out of 10, Wonderful, (67 reviews)
"The room appeared to be recently remodeled and was very modern. Of the 4 hotels that we stayed at on this trip, the bed/pillows were the most comfortable. Great view of the marina from our room balcony and public parking (free) was relatively easy. "
United States
Michael
The price is NT$3,497
NT$3,986 total
includes taxes & fees
Jun 7 - Jun 8
Lakkios

Fortaleza Charme House

Fortaleza Charme House
Santa Lucia
10.0 out of 10, Exceptional, (32 reviews)
"Perfect location. Very clean. "
United States
Marianna
The price is NT$6,463
NT$7,368 total
includes taxes & fees
Jun 8 - Jun 9
Fortaleza Charme House

B&B Siracusa

B&B Siracusa
Santa Lucia
9.0 out of 10, Wonderful, (60 reviews)
"Good location, very modern clean accommodation."
Canada
Malcolm
The price is NT$3,007
NT$3,428 total
includes taxes & fees
Jun 3 - Jun 4
B&B Siracusa

Piccolo Hotel Casa Mia

Piccolo Hotel Casa Mia
3.0 star property
Santa Lucia
8.6 out of 10, Excellent, (380 reviews)
"Nice place, few minutes walking to the Ortigia island. Many parking lots around!"
United Kingdom
Eliana
The price is NT$3,583
NT$4,085 total
includes taxes & fees
May 25 - May 26
Piccolo Hotel Casa Mia

Gymnasium

Gymnasium
3.0 star property
Santa Lucia
8.8 out of 10, Excellent, (40 reviews)
"Nice kitchen area, centrally located."
United States
Richard
The price is NT$2,256
NT$2,571 total
includes taxes & fees
May 24 - May 25
Gymnasium

Eos Serenity Suites

Eos Serenity Suites
Santa Lucia
The price is NT$4,551
NT$5,188 total
includes taxes & fees
Jun 4 - Jun 5
Eos Serenity Suites

Eos Sea View Apartment

Eos Sea View Apartment
Santa Lucia
The price is NT$7,361
NT$9,441 total
includes taxes & fees
Jun 12 - Jun 13
Eos Sea View Apartment

Grande Albergo Alfeo

Grande Albergo Alfeo
4.0 star property
Santa Lucia
8.6 out of 10, Excellent, (671 reviews)
"Good hotel. No complaints. Very conveniently located. Bathroom had a slight smell of mildew. Would stay there again. Very easy to access the city by foot from there and staff was nice."
United States
Rob
The price is NT$4,216
NT$4,806 total
includes taxes & fees
Jun 21 - Jun 22
Grande Albergo Alfeo

San Nicola Rooms Siracusa

San Nicola Rooms Siracusa
Santa Lucia
9.2 out of 10, Wonderful, (7 reviews)
"Very unique property and very well maintained! Great location and walking distance to Ortigia! Staff was friendly and breakfast was nice."
Canada
Trina
The price is NT$3,712
NT$4,231 total
includes taxes & fees
May 25 - May 26
San Nicola Rooms Siracusa

Hotel Mediterraneo

Hotel Mediterraneo
3.0 star property
Santa Lucia
7.8 out of 10, Good, (123 reviews)
"Very friendly and helpful staff."
United States
David
The price is NT$3,483
NT$3,971 total
includes taxes & fees
Jun 4 - Jun 5
Hotel Mediterraneo

Casa Miranda Boutique

Casa Miranda Boutique
Santa Lucia
8.0 out of 10, Very Good, (2 reviews)
"Great hotel. Close to everything 15min walk into Ortigia and the excursions dock. The staff are incredibly helpful and thoughtful. Rooms are clean and nice. The balcony had great views of the water and ortigia. Highly recommend to anyone visiting Siracusa! "
United States
Aria
The price is NT$7,830
NT$8,981 total
includes taxes & fees
Jun 4 - Jun 5
Casa Miranda Boutique

Re Dionisio Luxury Suites

Re Dionisio Luxury Suites
3.0 star property
Santa Lucia
8.8 out of 10, Excellent, (57 reviews)
"Spacious room, dated but comfortable."
United States
Kenneth
The price is NT$8,357
NT$9,560 total
includes taxes & fees
May 26 - May 27
Re Dionisio Luxury Suites
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Compare popular hotels in Santa Lucia

Property
Property class
Guest rating
Breakfast included
Pool
Spa
Pet friendly
WiFi included
Breakfast area
Giuggiulena Villa
3.0 star property
10.0
Exceptional
127 reviews
View
Rooftop terrace
Caportigia Boutique Hotel
5.0 star property
9.4
Exceptional
276 reviews
View
Superior Double Room | Frette Italian sheets, premium bedding, down comforters, desk
Fortuna Guest House
1.0 star property
9.2
Wonderful
16 reviews
View
Coffee/tea maker, electric kettle
Nostos rooms & Apartments
3.0 star property
9.0
Wonderful
278 reviews
View
Classic Room | View from room
Gymnasium
3.0 star property
8.8
Excellent
40 reviews
View

Where to stay in Santa Lucia

Find the best Santa Lucia areas and neighborhoods for the activities you enjoy most.

Ortigia

Travelers come to Ortigia for its seaside views, and you can see top attractions like Teatro dei Pupi and Cathedral of Syracuse while you're in town.

Neapolis

While visiting Neapolis, you might make a stop by sights like Roman Amphitheatre of Syracuse and Archaeological Park of Neapolis.

Grottasanta

Grottasanta is noteworthy for its historic sites, and you can make a stop at top attractions like Pista Ciclabile Siracusa and Ionian Sea.

Acradina

You'll enjoy the churches and seaside views in Acradina. You might want to make time for a stop at Ionian Sea or Capuchin Quarry.

Tiche

Gardens and restaurants are notable features of Tiche. You might consider a stop by Ionian Sea while you're exploring the neighborhood.

Top Santa Lucia Hotel Reviews

Frequently asked questions

What is Santa Lucia like?
Santa Lucia is a neighborhood that people enjoy for its interesting historical sites. Are you looking for Santa Lucia travel tips? Be sure to check out Porto Piccolo and Ionian Sea while you're in the neighborhood.
Where is the best place to stay in Santa Lucia?
Based on our traveler data, Grande Albergo Alfeo is one of the top choices for your stay in Santa Lucia. This hotel offers free breakfast and a restaurant. Other good choices for your stay in the area include Caportigia Boutique Hotel and Fortaleza Charme House.
How many hotels can I expect to find in Santa Lucia?
Expedia has 308 hotels and other accommodations in Santa Lucia to choose from, making this an ideal home base for exploring the greater Syracuse area.
If I need to cancel my hotel reservation in Santa Lucia, will I receive a refund?
Yes, you'll find most hotel bookings are fully refundable provided that you cancel prior to the accommodation's cancellation deadline, which is often 24 or 48 hours before your check-in date. If you booked a non-refundable reservation, you might be able to cancel it and be given a refund within 24 hours of your booking. Add your dates and click on "Search", then use the filter option "fully refundable" to get the best options available in Santa Lucia.
Where can I learn more about changing or cancelling my trip to Santa Lucia?
For more details about changing or cancelling your trip to Santa Lucia, click here.
What are the top things to see and do in Santa Lucia?
Landmarks in Santa Lucia that you won't want to miss include Syracuse Forum Ruins and Santa Lucia Bridge. Porto Piccolo and Ionian Sea are some other stops to visit in the neighborhood. A few places to visit in the area around Santa Lucia include Piazza Santa Lucia, Santa Lucia al Sepolcro Basilica, and Madonna delle Lacrime. When you're sightseeing in Syracuse, Papyrus Museum and Museo Archeologico Regionale Paolo Orsi are also worth a stop.