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Our top choices for Santa Ana hotels

Casco View Apartments

Casco View Apartments
3.5 star property
Santa Ana
9.0 out of 10, Wonderful, (100 reviews)
"Always an amazing stay"
United States
chris
The price is NT$2,835
NT$4,074 total
includes taxes & fees
Jul 1 - Jul 2
Casco View Apartments

Hostal La Cigarra

Hostal La Cigarra
2.0 star property
Santa Ana
7.6 out of 10, Good, (72 reviews)
"Excellent staff, close to metro and embassies. A good location, good room for a great price. I would stay again. "
United Kingdom
Mark
The price is NT$881
NT$969 total
includes taxes & fees
Jul 3 - Jul 4
Hostal La Cigarra

Hotel Riazor

Hotel Riazor
3.0 star property
Santa Ana
3.8 out of 10, (11 reviews)
"Rough neighborhood "
Canada
Del
The price is NT$861
NT$947 total
includes taxes & fees
Jun 30 - Jul 1
Hotel Riazor

Room-sofa Bed Stay Rooftop Pool & Gym, A

Room-sofa Bed Stay Rooftop Pool & Gym, A
2.0 star property
Santa Ana
2.0 out of 10, (1 review)
"You pay for a space in the apartment, it’s not the whole apartment be careful. The owner or whoever manages doesn’t give care about you as costumers they just want the money"
United States
Cristian Camilo Betancur
The price is NT$3,321
NT$3,653 total
includes taxes & fees
Jul 7 - Jul 8
Room-sofa Bed Stay Rooftop Pool & Gym, A

Hotel República

Hotel República
2.0 star property
Santa Ana
6.8 out of 10, (195 reviews)
"Very good ."
United States
Denice
The price is NT$932
NT$2,939 total
includes taxes & fees
Jun 30 - Jul 1
Hotel República

La Manzana Barrio Vivo by Wynwood

La Manzana Barrio Vivo by Wynwood
3.0 star property
Santa Ana
7.6 out of 10, Good, (18 reviews)
"Very clean and safe property"
United States
Javier Alberto Lindauer
The price is NT$1,913
NT$2,981 total
includes taxes & fees
Jul 2 - Jul 3
La Manzana Barrio Vivo by Wynwood

ART CASCO The Hotel

ART CASCO The Hotel
2.0 star property
Santa Ana
6.0 out of 10, (11 reviews)
"Walkable location and free secure parking! The price is really affordable, but the condition of the hotel is not the best"
United States
Eldris
The price is NT$1,174
NT$1,291 total
includes taxes & fees
Jul 30 - Jul 31
ART CASCO The Hotel

Riande Aeropuerto Hotel & Casino

Riande Aeropuerto Hotel & Casino
4.0 star property
19.8 km from Santa Ana
8.4 out of 10, Very Good, (1,814 reviews)
"The pool area is very nice"
United States
Matthew
The price is NT$3,765
NT$4,141 total
includes taxes & fees
Jul 4 - Jul 5
Riande Aeropuerto Hotel & Casino

Crowne Plaza Panama Airport by IHG

Crowne Plaza Panama Airport by IHG
4.0 star property
21.1 km from Santa Ana
8.6 out of 10, Excellent, (2,604 reviews)
"Great place to stay, restaurant is great also"
United States
Janet
The price is NT$4,049
NT$4,664 total
includes taxes & fees
Jul 9 - Jul 10
Crowne Plaza Panama Airport by IHG

Villa Caprichosa

Villa Caprichosa
2.5 star property
18.3 km from Santa Ana
9.8 out of 10, Exceptional, (78 reviews)
"Really good food, nice staff it was the best service! "
United States
junier
The price is NT$5,100
NT$5,611 total
includes taxes & fees
Jul 1 - Jul 2
Villa Caprichosa

ORHO Hotel Boutique 15 Minutes from PTY Airport

ORHO Hotel Boutique 15 Minutes from PTY Airport
2.0 star property
20.5 km from Santa Ana
8.8 out of 10, Excellent, (142 reviews)
"Lovely property, staff was always smiling and it's close to restaurants."
United States
Luis
The price is NT$3,260
NT$4,232 total
includes taxes & fees
Jul 1 - Jul 2
ORHO Hotel Boutique 15 Minutes from PTY Airport

Renaissance Panama City Hotel

Renaissance Panama City Hotel
5.0 star property
Campo Alegre, 3.4 km from Santa Ana
8.8 out of 10, Excellent, (236 reviews)
"Breakfast was very good, staff are very helpful and friendly "
United States
Farah
The price is NT$4,049
NT$4,453 total
includes taxes & fees
Jul 6 - Jul 7
Renaissance Panama City Hotel

Hotel Riu Plaza Panama

Hotel Riu Plaza Panama
5.0 star property
Campo Alegre, 3.6 km from Santa Ana
9.0 out of 10, Wonderful, (5,658 reviews)
"Great Location, good food."
United States
Yohan
The price is NT$4,388
NT$4,827 total
includes taxes & fees
Jul 1 - Jul 2
Hotel Riu Plaza Panama

Gamboa Rainforest Reserve

Gamboa Rainforest Reserve
3.5 star property
24.7 km from Santa Ana
8.0 out of 10, Very Good, (781 reviews)
"Great place to stay."
United States
Oscar
The price is NT$4,197
NT$4,616 total
includes taxes & fees
Jul 7 - Jul 8
Gamboa Rainforest Reserve

Arcadia Condo Suites

Arcadia Condo Suites
4.0 star property
Costa del Este, 10.2 km from Santa Ana
9.2 out of 10, Wonderful, (309 reviews)
"Very good place to stay and safe place..!"
United States
Somnueg
The price is NT$2,840
NT$4,808 total
includes taxes & fees
Jun 30 - Jul 1
Arcadia Condo Suites

The Beach House

The Beach House
3.0 star property
Amador, 4.8 km from Santa Ana
8.4 out of 10, Very Good, (440 reviews)
"Very nice small hotel, comfortable excellent location on Amador Causeway. Close to Albrook Mall, Casco, Viejo…"
United States
David
The price is NT$2,399
NT$2,638 total
includes taxes & fees
Jul 15 - Jul 16
The Beach House

Summit Rainforest Golf Resort & All Inclusive

Summit Rainforest Golf Resort & All Inclusive
4.0 star property
14.5 km from Santa Ana
8.4 out of 10, Very Good, (1,000 reviews)
"Excellent location and clean hotel"
United States
Mark
The price is NT$6,800
NT$7,480 total
includes taxes & fees
Jul 24 - Jul 25
Summit Rainforest Golf Resort & All Inclusive

The District Hotel Panama

The District Hotel Panama
3.0 star property
El Cangrejo, 3.8 km from Santa Ana
8.4 out of 10, Very Good, (5 reviews)
"The rooms are clean, the bed was very comfortable. They have been updating the rooms to include new beds. Breakfast is served on time, and is mostly Panamanian cuisine. They staff is very helpful. The area is walkable with stores and restaurants nearby. I would stay again."
United States
Terry
The price is NT$2,288
NT$2,516 total
includes taxes & fees
Jun 30 - Jul 1
The District Hotel Panama

MARINN Tropical Vibes Hotel

MARINN Tropical Vibes Hotel
3.5 star property
Amador, 4.8 km from Santa Ana
8.0 out of 10, Very Good, (258 reviews)
"The breakfast was good and lots of parking in a safe place "
United States
Tessa
The price is NT$2,474
NT$2,722 total
includes taxes & fees
Jun 30 - Jul 1
MARINN Tropical Vibes Hotel

The Westin Playa Bonita Panama

The Westin Playa Bonita Panama
5.0 star property
7.5 km from Santa Ana
8.0 out of 10, Very Good, (1,001 reviews)
"This is an excellent hotel and would highly recommend."
United States
Shernon
The price is NT$6,570
NT$7,227 total
includes taxes & fees
Jul 10 - Jul 11
The Westin Playa Bonita Panama
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Compare popular hotels in Santa Ana

Property
Property class
Guest rating
Breakfast included
Pool
Spa
Pet friendly
WiFi included
Outdoor pool, open 7:00 AM to 10:00 PM, pool umbrellas, sun loungers
Casco View Apartments
3.5 star property
9.0
Wonderful
100 reviews
View
Bar (on property)
Hostal La Cigarra
2.0 star property
7.6
Good
72 reviews
View
Beach shuttle
Hotel República
2.0 star property
6.8
195 reviews
View
Front of property
ART CASCO The Hotel
2.0 star property
6.0
11 reviews
View
Bar (on property)
Hotel Riazor
3.0 star property
3.8
11 reviews
View

Where to stay in Santa Ana

Find the best Santa Ana areas and neighborhoods for the activities you enjoy most.

Casco Viejo

Unique features of Casco Viejo include the historic sites and bars. Make a stop by Independence Square or Interoceanic Canal Museum while you're exploring the area.

Bella Vista

Bella Vista is highly notable for its popular shops, and you might want to visit top sights like Via Espana and Iglesia del Carmen. See more of Panama City by jumping on the metro at Iglesia del Carmen Station or Vía Argentina.

El Cangrejo

The abundant dining options and casinos are top of the list for many visitors to El Cangrejo. A stop by Via Espana or Crown Casino might round out your trip.

San Francisco

San Francisco is noteworthy for its restaurants, and you can make a stop at top attractions like Multiplaza Pacific Mall and Calle 50.

Calidonia

You might enjoy the shopping while in Calidonia. Via Espana is a notable sight, and you can get around town at Estación Lotería or Santo Tomas Station to see more of the city.

Top Santa Ana Hotel Reviews

Frequently asked questions

What's it like in Santa Ana?
Santa Ana is a neighborhood that travelers like for its seafood restaurants, shopping, and parks. Are you looking for Santa Ana travel tips? Be sure to check out Avenida Balboa and El Machetazo Santa Ana while you're in the neighborhood.
Where is the best hotel for a stay in Santa Ana?
Based on our traveler data, Casco View Apartments is one of the top choices for your stay in Santa Ana. This condo is a short 8-minute walk from Avenida Balboa, and it offers an outdoor pool and in-room kitchens.
How many hotels can I expect to find in Santa Ana?
Expedia has 120 hotels and other accommodations in Santa Ana to choose from, making this an ideal home base for exploring the greater Panama City area.
If I need to cancel my hotel reservation in Santa Ana, will I receive a refund?
Yes! Most hotel room reservations are refundable provided that you cancel before the accommodation's cancellation deadline, which is usually within 24-48 hours of the scheduled arrival. If you have a non-refundable reservation, it might still be possible to cancel it and be given a refund within a 24-hour period of your booking. Add dates, click "Search", then use the "fully refundable" filter to get top deals in Santa Ana.
Where can I learn more about changing or cancelling my trip to Santa Ana?
To find more details about picking new dates or cancelling your trip to Santa Ana, head over to our customer service page.
What is there to do in this Panama City neighborhood?
If you're looking forward to a day of shopping in Santa Ana, consider El Machetazo Santa Ana or Avenida Balboa, and pick out the perfect souvenir. When you're sightseeing in Panama City, Albrook Shopping Mall and Avenida Central are also worth a stop.