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Find hotels in Santa Ana, Panama City from NT$1,062

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Jul 15 - Jul 16
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Jul 16 - Jul 17
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Jul 18 - Jul 20
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Jul 25 - Jul 27

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Discover 1,462 Santa Ana hotels and places to stay, with room rates, reviews, and availability. Most hotels are fully refundable.

Casco View Apartments
Luxury Apartment | Balcony

Casco View Apartments

3.0 star property
9.2 out of 10, Wonderful, (41)
"I liked the buildings quietness and modern style."
Casco View Apartments
Casa Quijano 06 By Wynwood House
Apartment | Terrace/patio

Casa Quijano 06 By Wynwood House

4.0 star property
9.4 out of 10, Exceptional, (3)
"The apartment itself was very nice, very spacious, clean, newer furniture. Just know it’s on the third floor and there is no elevator. I didn’t see a sign on the building so it was a bit tricky to figure out which door to go to after being dropped off by the Uber. Email communication from property with building entry code and picture of the property was helpful. There are two balconies but all you really see is the apartment immediately in front of you, and so just know people can see you if you...
The price is NT$2,104
NT$3,278 total
includes taxes & fees
Jul 27 - Jul 28
Casa Quijano 06 By Wynwood House
Hostal La Cigarra
Bar (on property)

Hostal La Cigarra

2.5 star property
7.4 out of 10, Good, (47)
"Great budget place to stay. Friendly, clean, good location. Would be happy to stay again in future."
Hostal La Cigarra
ART CASCO The Hotel
Front of property

ART CASCO The Hotel

2.0 star property
6.0 out of 10, (3)
"Tranquilo"
ART CASCO The Hotel
Hotel República
Balcony

Hotel República

2.0 star property
6.6 out of 10, (171)
"The wifi is strong enough to use for work. "
Hotel República
La Manzana by Wynwood House
Apartment (20) | 1 bedroom, iron/ironing board, free WiFi, bed sheets

La Manzana by Wynwood House

3.5 star property
6.8 out of 10, (11)
"Great hotel. Very close to Casco viejo"
The price is NT$1,266
NT$1,979 total
includes taxes & fees
Jul 16 - Jul 17
La Manzana by Wynwood House
Room-sofa Bed Stay Rooftop Pool & Gym, A
Room, Multiple Bedrooms, Accessible, Smoking | Pool | Outdoor pool

Room-sofa Bed Stay Rooftop Pool & Gym, A

2.0 star property
The price is NT$4,111
NT$4,522 total
includes taxes & fees
Jul 22 - Jul 23
Room-sofa Bed Stay Rooftop Pool & Gym, A
w Charming 1BR in Santa Ana s Best Area
Apartment | 1 bedroom, Internet

w Charming 1BR in Santa Ana s Best Area

2.0 star property
The price is NT$1,789
NT$3,013 total
includes taxes & fees
Jul 21 - Jul 22
w Charming 1BR in Santa Ana s Best Area
Hotel Riazor
Single Room | 1 bedroom, free WiFi, bed sheets

Hotel Riazor

3.0 star property
3.8 out of 10, (10)
"Rough neighborhood "
Hotel Riazor
The Executive Hotel
Lobby

The Executive Hotel

3.5 star property
9.2 out of 10, Wonderful, (1012)
"Staff was very pleasant! Breakfast was good!"
The price is NT$2,815
NT$3,096 total
includes taxes & fees
Jul 16 - Jul 17
The Executive Hotel
Novotel Panama City
Front of property

Novotel Panama City

4.0 star property
9.0 out of 10, Wonderful, (1015)
"Great value great rooms and breakfast "
The price is NT$2,875
NT$3,162 total
includes taxes & fees
Jul 20 - Jul 21
Novotel Panama City
Central Hotel Panama Casco Viejo
47-inch flat-screen TV with cable channels, TV

Central Hotel Panama Casco Viejo

4.0 star property
9.0 out of 10, Wonderful, (942)
"Love the location and the restaurant inside the hotel was phenomenal."
Central Hotel Panama Casco Viejo
Hotel Coral Suites
Reception

Hotel Coral Suites

3.5 star property
9.0 out of 10, Wonderful, (1002)
"Nice Hotel "
The price is NT$2,025
NT$2,227 total
includes taxes & fees
Jul 17 - Jul 18
Hotel Coral Suites
Plaza Paitilla Inn Hotel
View from property

Plaza Paitilla Inn Hotel

3.5 star property
9.4 out of 10, Exceptional, (2075)
"Great stay!"
The price is NT$4,412
NT$4,853 total
includes taxes & fees
Jul 20 - Jul 21
Plaza Paitilla Inn Hotel
Marriott Executive Apartments Panama City, Finisterre
Outdoor pool

Marriott Executive Apartments Panama City, Finisterre

4.0 star property
8.8 out of 10, Excellent, (613)
"This property was perfect for our family of 4. The hotel staff was kind, the room was clean, parking was available, and it was within walking distance of many restaurants. The property also offered room service, laundry services, and a rather good breakfast (at an additional cost)."
The price is NT$2,955
NT$3,251 total
includes taxes & fees
Aug 3 - Aug 4
Marriott Executive Apartments Panama City, Finisterre
Courtyard by Marriott Panama Metromall
Breakfast, lunch, dinner served; international cuisine

Courtyard by Marriott Panama Metromall

4.0 star property
8.8 out of 10, Excellent, (1008)
"I really enjoyed my stay there. "
The price is NT$3,402
NT$3,742 total
includes taxes & fees
Jul 21 - Jul 22
Courtyard by Marriott Panama Metromall
Sortis Hotel, Spa & Casino, Autograph Collection by Marriott
Property amenity

Sortis Hotel, Spa & Casino, Autograph Collection by Marriott

4.5 star property
8.8 out of 10, Excellent, (969)
"This hotel was really nice, clean and modern. Staff was always helpful. Food and drinks right on the property so you don’t have to venture out too much or late in the night. My fiancé and I enjoyed our stay. "
The price is NT$4,645
NT$5,110 total
includes taxes & fees
Jul 20 - Jul 21
Sortis Hotel, Spa & Casino, Autograph Collection by Marriott
Principe Hotel and Suites
Front of property - evening/night

Principe Hotel and Suites

3.0 star property
9.0 out of 10, Wonderful, (1401)
"Good place to stay. "
The price is NT$1,709
NT$1,880 total
includes taxes & fees
Jul 21 - Jul 22
Principe Hotel and Suites
Magnolia Inn
Living area

Magnolia Inn

2.0 star property
9.0 out of 10, Wonderful, (358)
"We had a really great stay, great views of Casco Viejo, amazing staff, and very cozy to return to after a day out!"
The price is NT$1,963
NT$2,160 total
includes taxes & fees
Aug 3 - Aug 4
Magnolia Inn
MARINN PLACE Financial District
Outdoor pool

MARINN PLACE Financial District

3.5 star property
9.2 out of 10, Wonderful, (289)
"Great location, great staff, breakfast was also good. For the price, everything was well worth it, would absolutely recommend."
The price is NT$4,744
NT$5,218 total
includes taxes & fees
Jul 16 - Jul 17
MARINN PLACE Financial District
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Santa Ana

Find the best Santa Ana areas and neighborhoods for the activities you enjoy most.
Casco Viejo map

Casco Viejo

Unique features of Casco Viejo include the historic sites and bars. Make a stop by Metropolitan Cathedral of Panama or Interoceanic Canal Museum while you're exploring the area.

Bella Vista map

Bella Vista

1 out of top 10 points of interest in this area

Bella Vista is highly notable for its popular shops, and you might want to visit top sights like Via Espana and Iglesia del Carmen. See more of Panama City by jumping on the metro at Iglesia del Carmen Station or Vía Argentina.

El Cangrejo map

El Cangrejo

The abundant dining options and casinos are top of the list for many visitors to El Cangrejo. A stop by Crown Casino or Luxor Towers might round out your trip.

San Francisco map

San Francisco

1 out of top 10 points of interest in this area

San Francisco is noteworthy for its restaurants, and you can make a stop at top attractions like Multiplaza Pacific Mall and Calle 50.

Punta Paitilla map

Punta Paitilla

Travelers come to Punta Paitilla for its abundant dining options, and you can see top attractions like Avenida Balboa and Multicentro Panama while you're in town.

Frequently asked questions

What's it like in Santa Ana?

Santa Ana is a neighborhood that travelers like for its seafood restaurants, shopping, and parks. Are you looking for Santa Ana travel tips? Be sure to check out Cinta Costera and Avenida Balboa while you're in the neighborhood.

Where is the best hotel for a stay in Santa Ana?

Based on Expedia customer reviews, Hotel República is the highest ranked property in Santa Ana. This hotel is a short 4-minute walk from Avenida Balboa, and it offers a rooftop terrace and free WiFi. Another top choice in the area is Hostal La Cigarra.

How many hotels can I expect to find in Santa Ana?

Expedia has 101 hotels and other accommodations in Santa Ana to choose from, making this an ideal home base for exploring the greater Panama City area.

If I need to cancel my hotel reservation in Santa Ana, will I receive a refund?

Yes! Most hotel room reservations are refundable provided that you cancel before the accommodation's cancellation deadline, which is usually within 24-48 hours of the scheduled arrival. If you have a non-refundable reservation, it might still be possible to cancel it and be given a refund within a 24-hour period of your booking. Add dates, click "Search", then use the "fully refundable" filter to get top deals in Santa Ana.

Where can I learn more about changing or cancelling my trip to Santa Ana?

To find more details about picking new dates or cancelling your trip to Santa Ana, head over to our customer service page.

What is there to do in this Panama City neighborhood?

If you're looking forward to a day of shopping in Santa Ana, consider Avenida Central or Avenida Balboa, and pick out the perfect souvenir. A visit to Cinta Costera is also worth the trip while you're discovering the neighborhood. Albrook Shopping Mall, Amador Theater, and Museum of Contemporary Art Panama are just a few of the places to visit in and around Santa Ana. When you're sightseeing in Panama City, Mi Pueblito and Iglesia de la Merced are also worth a stop.