Find Business Hotels in Sanford, ME

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Check availability on Sanford Business Hotels

Our top choices for Sanford business-friendly hotels

Free daily buffet breakfast
Holiday Inn Express Wells-Ogunquit-Kennebunk by IHG

Holiday Inn Express Wells-Ogunquit-Kennebunk by IHG

Holiday Inn Express Wells-Ogunquit-Kennebunk by IHG
3.0 star property
Wells
9.2 out of 10, Wonderful, (574)
"Room was clean and the gentleman at the reception desk was extremely kind "
United States
Christopher
The price is NT$2,196
NT$2,393 total
includes taxes & fees
Dec 23 - Dec 24
Holiday Inn Express Wells-Ogunquit-Kennebunk by IHG
Terrace/patio
Home2 Suites By Hilton Kittery

Home2 Suites By Hilton Kittery

Home2 Suites By Hilton Kittery
3.0 star property
Kittery
9.4 out of 10, Exceptional, (42)
"Excellent room and facilities "
United States
Krishna Prasad
The price is NT$3,461
NT$3,772 total
includes taxes & fees
Jan 1 - 2026/1/2
Home2 Suites By Hilton Kittery
Lobby
Garrison Hotel & Suites Dover-Portsmouth, an Ascend Collection Hotel

Garrison Hotel & Suites Dover-Portsmouth, an Ascend Collection Hotel

Garrison Hotel & Suites Dover-Portsmouth, an Ascend Collection Hotel
2.5 star property
Dover
9.2 out of 10, Wonderful, (1005)
"Great value. Pleasant experience. Would stay again."
United States
Todd W
The price is NT$2,936
NT$3,185 total
includes taxes & fees
Dec 29 - Dec 30
Garrison Hotel & Suites Dover-Portsmouth, an Ascend Collection Hotel
Lobby
Hampton Inn & Suites Kittery-Portsmouth

Hampton Inn & Suites Kittery-Portsmouth

Hampton Inn & Suites Kittery-Portsmouth
2.5 star property
Kittery
9.2 out of 10, Wonderful, (1005)
"Great location "
United States
Gary
The price is NT$3,189
NT$3,476 total
includes taxes & fees
Dec 23 - Dec 24
Hampton Inn & Suites Kittery-Portsmouth
Exterior
Port Inn and Suites Portsmouth, an Ascend Collection Hotel

Port Inn and Suites Portsmouth, an Ascend Collection Hotel

Port Inn and Suites Portsmouth, an Ascend Collection Hotel
3.0 star property
Portsmouth
8.2 out of 10, Very Good, (1009)
"Excellent location and easy access to get into the downtown. "
United States
Liza
The price is NT$2,795
NT$3,032 total
includes taxes & fees
Jan 7 - 2026/1/8
Port Inn and Suites Portsmouth, an Ascend Collection Hotel
Lobby sitting area
Microtel Inn & Suites by Wyndham York

Microtel Inn & Suites by Wyndham York

Microtel Inn & Suites by Wyndham York
2.0 star property
York
7.8 out of 10, Good, (1001)
"Clean room, nice staff, renovations on main level but was roomed in an area already renovated."
United States
Rebecca
The price is NT$2,980
NT$3,248 total
includes taxes & fees
Jan 3 - 2026/1/4
Microtel Inn & Suites by Wyndham York
Restaurant
Hampton Inn & Suites Wells-Ogunquit

Hampton Inn & Suites Wells-Ogunquit

Hampton Inn & Suites Wells-Ogunquit
2.5 star property
Wells
9.4 out of 10, Exceptional, (1009)
"excellent hotel!"
United States
Diane
The price is NT$3,073
NT$3,350 total
includes taxes & fees
Jan 11 - 2026/1/12
Hampton Inn & Suites Wells-Ogunquit
Lobby
Howard Johnson by Wyndham Portsmouth

Howard Johnson by Wyndham Portsmouth

Howard Johnson by Wyndham Portsmouth
2.0 star property
Portsmouth
8.6 out of 10, Excellent, (1003)
"An awesome place to stay!"
United States
Nicholas
The price is NT$2,675
NT$2,903 total
includes taxes & fees
Dec 25 - Dec 26
Howard Johnson by Wyndham Portsmouth
Free daily continental breakfast
Coachman Inn

Coachman Inn

Coachman Inn
2.5 star property
Kittery
7.6 out of 10, Good, (1001)
"Great place to stay."
Canada
Linda
The price is NT$2,089
NT$2,380 total
includes taxes & fees
Dec 29 - Dec 30
Coachman Inn
Individually furnished, desk, iron/ironing board, free cribs/infant beds
Ramada by Wyndham Saco/Old Orchard Beach Area

Ramada by Wyndham Saco/Old Orchard Beach Area

Ramada by Wyndham Saco/Old Orchard Beach Area
2.5 star property
Saco
7.4 out of 10, Good, (1004)
"Check-in was quick & easy. Our room was clean & comfortable."
United States
Julie
The price is NT$2,359
NT$2,571 total
includes taxes & fees
Dec 22 - Dec 23
Ramada by Wyndham Saco/Old Orchard Beach Area
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Top Sanford Hotel Reviews

Garrison Hotel & Suites Dover-Portsmouth, an Ascend Collection Hotel

Garrison Hotel & Suites Dover-Portsmouth, an Ascend Collection Hotel

10/10 Excellent
"Place was as described "
Mark 1-night trip
Posted 1 day ago
Garrison Hotel & Suites Dover-Portsmouth, an Ascend Collection Hotel

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Frequently asked questions

How much do business-friendly hotels in Sanford cost?
You'll pay between NT$2,380 and NT$3,772 per night for business-friendly hotels in Sanford. Awesome deals on stays that cater to people traveling for work as just a click away on Expedia. These prices were available on Expedia within the past 7 days, for a hotel booking with a check-in date within the next year. Prices reflect current offers and availability is subject to change. Additional terms may apply.
Why book your business-friendly hotel in Sanford with Expedia?
With handy amenities like conference rooms, laundry facilities and free parking, our business-friendly properties come with everything you'll need to get the job done — and then kick back! Enter your preferred travel dates and destination and we'll help you plan the rest.
How can I find cheap business-friendly hotels in Sanford?
When work takes you to Sanford, our "business friendly" filter will help you find the perfect hotel. From WiFi to meeting rooms and work desks, they come with the amenities you need for a productive and comfortable stay. Another handy tip? Narrow your search by your budget and preferred star rating to see the most affordable stays.
What is there to do in Sanford near my business-friendly hotel?
Sanford has enough sights and activities to keep you busy for weeks, starting with Bowl A Rama. Mousam Lake, Kennebunk Pond and Blueberry Hill are other well-known attractions. If your business trip gives you time to spare, Swan Pond and Pine Hollow Little Par Three Golf Course are great additions to your itinerary.