Otay Mesa, CA
San Diego
Popular places to visit
San Diego Zoo
See nature up-close and personal at one of the country’s largest and most educational zoos.
San Diego Convention Center
During your trip, find out what's happening at San Diego Convention Center, a top convention center in San Diego. Experience the area's fascinating museums and entertainment choices.
SeaWorld
Animal interaction, entertaining rides and informative exhibits are all on offer at this family favorite destination.
Mission Bay
Mingle with eccentric locals at bohemian beaches, soak up the sun on a Jet Ski and fish from marshy islands at San Diego’s premier water park.
Balboa Park
Culture and nature converge in this diverse park located in the heart of the city.
Port of San Diego
Explore the waterfront in San Diego with a trip to Port of San Diego. Wander the seaside and beautiful beaches in the area.
Otay Mesa Hotel Deals
Sheraton San Diego Resort
VERY NICE
Reviewed on 2026/1/3
Bay Club Hotel & Marina
Helpful staff, great services at the restaurant and comfortable room.
Reviewed on 2026/1/4
Courtyard by Marriott San Diego Downtown Little Italy
Room was nice great view
Reviewed on 2025/12/31
The DEXTRO Little Italy, BW Premier Collection
Great place to stay. The bar inside is awesome The bartender Berto is very good making all different kinds of drinks and a very attoto all costumery. Overall my stay was pleasant.
Reviewed on 2026/1/4
DoubleTree by Hilton Hotel San Diego - Mission Valley
Hotel was nice. Room was clean and spacious. Close to 2 malls and plenty of dining options.Indoor pool was a plus and clean. Staff at check in was mediocre. Staff in the morning was very friendly.
Reviewed on 2026/1/1
Hilton San Diego Mission Valley
Clean, comfortable room. Reasonable price considering location!
Reviewed on 2026/1/4
Other neighborhoods around Otay Mesa
East Village
Travelers choose East Village for its lively bars. Hop aboard the metro at City College Trolley Station or Park and Market Trolley Station and check out top sights like Petco Park.
Gaslamp Quarter
Downtown San Diego's historic district boasts Victorian-era buildings, now housing vibrant restaurants, shops, and entertainment venues. Stroll from Broadway to Harbor Drive, and 4th to 6th Avenue, admiring the newly installed gaslamps at Market Street.
Downtown San Diego
Cultural and financial hub, Downtown San Diego boasts the Symphony, Opera, theaters, museums, and historic sites like Gaslamp Quarter. Enjoy diverse shops, dining, nightlife, and convenient public transport options.
Marina District
Known for its fantastic nightlife and captivating waterfront views, there's plenty to explore in Marina District. Check out top attractions like Seaport Village and The Rady Shell at Jacobs Park, and jump on the metro at Seaport Village Station or Convention Center Station to see more of the city.
North Park
North Park is well-liked for its restaurants. You can also take some time to explore sights in the surrounding area like San Diego Zoo and San Diego Natural History Museum.
Little Italy
Little Italy is popular for its captivating waterfront views. Explore top sights like Maritime Museum of San Diego and San Diego Bay, and you can get around town on the metro at County Center - Little Italy Station.
