Otay Mesa, CA
San Diego
Popular places to visit
San Diego Zoo
See nature up-close and personal at one of the country’s largest and most educational zoos.
San Diego Convention Center
During your trip, find out what's happening at San Diego Convention Center, a top convention center in San Diego. Experience the area's entertainment choices and fascinating museums.
SeaWorld
Animal interaction, entertaining rides and informative exhibits are all on offer at this family favorite destination.
Mission Bay
Mingle with eccentric locals at bohemian beaches, soak up the sun on a Jet Ski and fish from marshy islands at San Diego’s premier water park.
Mission Beach
A favorite vacation spot for 100 years, this seaside village combines old-fashioned charm with modern amenities.
Petco Park
Purchase a hot dog and watch the San Diego Padres, California’s southernmost Major League Baseball team, play on their home field.
Otay Mesa Hotel Deals
Paradise Point Resort & Spa
After waiting three hours past our check in time, we were finally able to get into our room. It was clear there was flooding (presumably from a toilet) in the room, which had a terrible odor of bleach (I have two young boys, one with autism, who are very sensitive to strong smells… especially something ...
Reviewed on 2026/2/23
Bay Club Hotel & Marina
Clean room in a great location. So many things in walking distance, and yet it seemed remote and quiet on the property. The entire staff that we interacted with were all genuinely nice and friendly people. I noticed all of the comments about “breakfast lady”, and they are all 100% accurate! She was ...
Reviewed on 2026/2/23
Hard Rock Hotel San Diego
The windows in the rooms are too thin. We could everything outside until 3am.
Reviewed on 2026/2/24
The DEXTRO Little Italy, BW Premier Collection
We stayed here because of the great reviews and they still exceeded our expectations. Every member of staff was 10 out of 10! Great attitudes, friendly, super helpful, and the rooms were very nice, clean and comfortable. Location was just close enough to uber everywhere within a few mins but not ...
Reviewed on 2026/2/24
Best Western Seven Seas
Great space
Reviewed on 2026/2/24
San Diego Mission Bay Resort
The room, bathroom in particular, was well worn making it look almost dirty. And, the beds were the most uncomfortable things I've ever stayed on. Truly, that was 3 of the worst nights of rest I've had in a long time.
Reviewed on 2026/2/23
Other neighborhoods around Otay Mesa
East Village
Travelers choose East Village for its lively bars. Hop aboard the metro at City College Trolley Station or Park and Market Trolley Station and check out top sights like Petco Park.
Gaslamp Quarter
Downtown San Diego's historic district boasts Victorian-era buildings, now housing vibrant restaurants, shops, and entertainment venues. Stroll from Broadway to Harbor Drive, and 4th to 6th Avenue, admiring the newly installed gaslamps at Market Street.
Downtown San Diego
Cultural and financial hub, Downtown San Diego boasts the Symphony, Opera, theaters, museums, and historic sites like Gaslamp Quarter. Enjoy diverse shops, dining, nightlife, and convenient public transport options.
North Park
North Park is well-liked for its restaurants. You can also take some time to explore sights in the surrounding area like San Diego Zoo and San Diego Natural History Museum.
Little Italy
Little Italy is popular for its captivating waterfront views. Explore top sights like Maritime Museum of San Diego and San Diego Bay, and you can get around town on the metro at County Center - Little Italy Station.
Hillcrest
Visitors to Hillcrest enjoy its restaurants, and if you want to do some exploring, Marston House is worth a stop.
