Otay Mesa, CA
San Diego
Popular places to visit
San Diego Zoo
See nature up-close and personal at one of the country’s largest and most educational zoos.
San Diego Convention Center
During your trip, find out what's happening at San Diego Convention Center, a top convention center in San Diego. Experience the area's entertainment choices and fascinating museums.
SeaWorld
Animal interaction, entertaining rides and informative exhibits are all on offer at this family favorite destination.
Mission Bay
Mingle with eccentric locals at bohemian beaches, soak up the sun on a Jet Ski and fish from marshy islands at San Diego’s premier water park.
Mission Beach
A favorite vacation spot for 100 years, this seaside village combines old-fashioned charm with modern amenities.
Petco Park
Purchase a hot dog and watch the San Diego Padres, California’s southernmost Major League Baseball team, play on their home field.
Otay Mesa Hotel Deals
Paradise Point Resort & Spa
Room was not ready at time of check in 4pm had to wait 1 hour checked in at 5pm overall room was clean view was good
Reviewed on 2026/2/23
Bay Club Hotel & Marina
We stayed for two nights, a family of 8 with three rooms. The rooms were very spacious and the balconies are definitely a plus. Our only frustration was coin laundry facilities with no way to get change. As a family on a little road trip, laundry was a necessity but overall a nice stay.
Reviewed on 2026/2/22
Hard Rock Hotel San Diego
El Cuarto necesitaba mas limpieza y no es la gran cosa el hotel
Reviewed on 2026/2/23
The DEXTRO Little Italy, BW Premier Collection
Check in was great…but all downhill from there. I booked this place based on ratings and was sorely disappointed. Small things like non-functioning power outlet, one packet of coffee to a dead phone. Typically don’t use room phone, but when awakened by loud partiers in the room above, I would’ve ...
Reviewed on 2026/2/23
Best Western Seven Seas
clean
Reviewed on 2026/2/23
San Diego Mission Bay Resort
Great location for us. Helpful staff. Beautiful views.
Reviewed on 2026/2/22
Other neighborhoods around Otay Mesa
East Village
Travelers choose East Village for its lively bars. Hop aboard the metro at City College Trolley Station or Park and Market Trolley Station and check out top sights like Petco Park.
Gaslamp Quarter
Downtown San Diego's historic district boasts Victorian-era buildings, now housing vibrant restaurants, shops, and entertainment venues. Stroll from Broadway to Harbor Drive, and 4th to 6th Avenue, admiring the newly installed gaslamps at Market Street.
Downtown San Diego
Cultural and financial hub, Downtown San Diego boasts the Symphony, Opera, theaters, museums, and historic sites like Gaslamp Quarter. Enjoy diverse shops, dining, nightlife, and convenient public transport options.
North Park
North Park is well-liked for its restaurants. You can also take some time to explore sights in the surrounding area like San Diego Zoo and San Diego Natural History Museum.
Little Italy
Little Italy is popular for its captivating waterfront views. Explore top sights like Maritime Museum of San Diego and San Diego Bay, and you can get around town on the metro at County Center - Little Italy Station.
Hillcrest
Visitors to Hillcrest enjoy its restaurants, and if you want to do some exploring, Marston House is worth a stop.
