Find hotels in Otay Mesa, San Diego from NT$2,095

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Discover 4,610 Otay Mesa hotels and places to stay, with room rates, reviews, and availability. Most hotels are fully refundable.

Quality Suites San Diego Otay Mesa
Two single beds with green bedspreads, a small armchair, and a bedside table with a lamp are featured in this cozy space.

Quality Suites San Diego Otay Mesa

2.5 star property
7.2 out of 10, Good, (1005)
"Great location and spacious room "
The price is NT$3,253
NT$3,700 total
includes taxes & fees
Aug 11 - Aug 12
Quality Suites San Diego Otay Mesa
Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG
Welcome to Holiday Inn Express & Suites, featuring a modern design with a lush entrance area and a prominent address sign.

Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG

2.5 star property
7.8 out of 10, Good, (1417)
"Great stay, close to the Cross Border Xpress "
The price is NT$3,671
NT$4,175 total
includes taxes & fees
Aug 16 - Aug 17
Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG
Hotel Zindel
Terrace/patio

Hotel Zindel

2.0 star property
7.6 out of 10, Good, (514)
"Great stay "
Hotel Zindel
Wyndham San Diego Bayside
Enjoy dining under the shade of a palm tree in our outdoor dining area, surrounded by a beautifully landscaped garden.

Wyndham San Diego Bayside

4.0 star property
8.4 out of 10, Very Good, (5847)
"Great stay!"
The price is NT$4,541
NT$6,002 total
includes taxes & fees
Sep 3 - Sep 4
Wyndham San Diego Bayside
The Horton Grand, Downtown/Gaslamp Quarter
Relax and socialize in our elegantly furnished bar area, featuring a variety of seating options and a selection of beverages.

The Horton Grand, Downtown/Gaslamp Quarter

3.5 star property
9.0 out of 10, Wonderful, (2447)
"Great location and friendly staff!"
The Horton Grand, Downtown/Gaslamp Quarter
Palihotel San Diego Gaslamp Quarter
Relax on the rooftop with striped sofas and armchairs, surrounded by lush greenery and city views.

Palihotel San Diego Gaslamp Quarter

4.0 star property
8.8 out of 10, Excellent, (1610)
"Great place!"
The price is NT$2,820
NT$3,264 total
includes taxes & fees
Aug 27 - Aug 28
Palihotel San Diego Gaslamp Quarter
Residence Inn by Marriott San Diego Downtown/Gaslamp Quarter
Experience the vibrant city life from our corner location, with stunning views of the surrounding streets.

Residence Inn by Marriott San Diego Downtown/Gaslamp Quarter

3.0 star property
9.0 out of 10, Wonderful, (1052)
"We had a great stay!"
The price is NT$4,035
NT$4,670 total
includes taxes & fees
Sep 1 - Sep 2
Residence Inn by Marriott San Diego Downtown/Gaslamp Quarter
Hard Rock Hotel San Diego
Relax by the pool surrounded by lounge chairs and umbrellas.

Hard Rock Hotel San Diego

4.0 star property
9.0 out of 10, Wonderful, (2794)
"Great hotel"
The price is NT$4,921
NT$7,077 total
includes taxes & fees
Aug 30 - Aug 31
Hard Rock Hotel San Diego
Gaslamp Plaza Suites
Experience the grandeur of our lobby, featuring a stunning chandelier, elegant marble floor, and a beautifully designed reception desk.

Gaslamp Plaza Suites

3.5 star property
8.8 out of 10, Excellent, (1006)
"Great place and location. Nice rooftop"
The price is NT$3,104
NT$3,530 total
includes taxes & fees
Aug 27 - Aug 28
Gaslamp Plaza Suites
Best Western Plus Marina Gateway Hotel
Two large beds with blue and white bedding, a desk, and a potted plant adorn this stylish room.

Best Western Plus Marina Gateway Hotel

3.5 star property
9.2 out of 10, Wonderful, (3192)
"Enjoyed my stay"
The price is NT$4,271
NT$4,706 total
includes taxes & fees
Aug 17 - Aug 18
Best Western Plus Marina Gateway Hotel
Best Western Plus Suites Hotel Coronado Island
Relax by the serene pool surrounded by lush palm trees and lounge chairs.

Best Western Plus Suites Hotel Coronado Island

2.5 star property
8.8 out of 10, Excellent, (1006)
"Great area"
The price is NT$5,920
NT$6,512 total
includes taxes & fees
Aug 17 - Aug 18
Best Western Plus Suites Hotel Coronado Island
Staypineapple, Hotel Z, Gaslamp San Diego
Relax in a stylish room with a large bed, wooden headboard, and cozy armchair.

Staypineapple, Hotel Z, Gaslamp San Diego

3.0 star property
9.4 out of 10, Exceptional, (1007)
"Staff are nice and the property is situated in a great area. "
The price is NT$3,678
NT$5,120 total
includes taxes & fees
Aug 26 - Aug 27
Staypineapple, Hotel Z, Gaslamp San Diego
The Sofia Hotel
Enter The Sofia Hotel through a grand, arched doorway surrounded by lush topiary and a warm, inviting glow.

The Sofia Hotel

3.5 star property
8.4 out of 10, Very Good, (1508)
"Great stay"
The Sofia Hotel
El Cordova Hotel on Coronado Island
Enter a spacious lobby with high ceilings and a warm atmosphere, featuring a staircase and lush greenery.

El Cordova Hotel on Coronado Island

3.5 star property
8.8 out of 10, Excellent, (1005)
"Loved our stay at El Cordova Hotel! The on-site restaurant was super convenient, the whole place had a cozy, homey vibe, and we were just minutes from Coronado Beach. Excellent experience all around!"
The price is NT$7,557
NT$8,328 total
includes taxes & fees
Sep 1 - Sep 2
El Cordova Hotel on Coronado Island
Loews Coronado Bay Resort
Enjoy waterfront views and access to a marina with boats available for recreational use.

Loews Coronado Bay Resort

4.0 star property
8.8 out of 10, Excellent, (1011)
"Loved our stay very accommodating "
The price is NT$5,939
NT$7,950 total
includes taxes & fees
Sep 1 - Sep 2
Loews Coronado Bay Resort
AC Hotel by Marriott San Diego Downtown Gaslamp Quarter
Relax in a cozy seating area with cushioned booths and armchairs, surrounded by potted plants and books.

AC Hotel by Marriott San Diego Downtown Gaslamp Quarter

4.0 star property
8.8 out of 10, Excellent, (892)
"This is my favorite hotel in San Diego for value along with pool and gym."
The price is NT$4,805
NT$5,561 total
includes taxes & fees
Aug 14 - Aug 15
AC Hotel by Marriott San Diego Downtown Gaslamp Quarter
Super 8 by Wyndham El Cajon/San Diego
Welcome to the reception area, where a friendly staff is available to assist with your stay. A staircase leads to additional floors, and a clock keeps perfect time.

Super 8 by Wyndham El Cajon/San Diego

2.0 star property
7.8 out of 10, Good, (1004)
"Great place "
The price is NT$2,659
NT$2,925 total
includes taxes & fees
Aug 11 - Aug 12
Super 8 by Wyndham El Cajon/San Diego
The Bristol Hotel San Diego
Welcome to The Bristol, featuring a sleek glass facade and modern design.

The Bristol Hotel San Diego

3.5 star property
8.4 out of 10, Very Good, (1353)
"Great stay"
The Bristol Hotel San Diego
Bay Club Hotel & Marina
Enjoy a tranquil marina view from your balcony, complete with a table for two.

Bay Club Hotel & Marina

3.5 star property
9.0 out of 10, Wonderful, (2785)
"Great stay"
The price is NT$4,539
NT$5,217 total
includes taxes & fees
Sep 1 - Sep 2
Bay Club Hotel & Marina
Days Inn by Wyndham San Diego-East/El Cajon
Relax in this serene space with a large bed, ocean-inspired artwork, and a cozy reading nook by the window.

Days Inn by Wyndham San Diego-East/El Cajon

2.0 star property
7.6 out of 10, Good, (1003)
"Clean a quiet place"
The price is NT$2,765
NT$3,047 total
includes taxes & fees
Sep 1 - Sep 2
Days Inn by Wyndham San Diego-East/El Cajon
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Where to stay in Otay Mesa

Find the best Otay Mesa areas and neighborhoods for the activities you enjoy most.
US Grant Hotel
Downtown San Diego map

Downtown San Diego

2 out of top 10 points of interest in this area

Cultural and financial hub, Downtown San Diego boasts the Symphony, Opera, theaters, museums, and historic sites like Gaslamp Quarter. Enjoy diverse shops, dining, nightlife, and convenient public transport options.

Belmont Park showing rides and a garden
Mission Beach map

Mission Beach

Spanning nearly two miles of oceanfront, this sandbar community offers sunbathing, surfing, and beach volleyball, with nearby attractions like Belmont Park's Giant Dipper Roller Coaster and SeaWorld in Mission Bay Park.

Pacific Beach Park showing a beach
Pacific Beach map

Pacific Beach

Boasting a lively nightlife scene, Pacific Beach offers miles of sandy shores, a bustling 3.2-mile boardwalk, and attractions like Crystal Pier and Kate Sessions Park. Enjoy local shops, bars, and eateries along the vibrant walkway.

Gaslamp Quarter showing signage, night scenes and street scenes
Gaslamp Quarter map

Gaslamp Quarter

Downtown San Diego's historic district boasts Victorian-era buildings, now housing vibrant restaurants, shops, and entertainment venues. Stroll from Broadway to Harbor Drive, and 4th to 6th Avenue, admiring the newly installed gaslamps at Market Street.

Ocean Beach
Ocean Beach map

Ocean Beach

Ocean Beach is known for its stunning beaches, and with sights like Ocean Beach Pier and Dog Beach, you won't get bored spending a day wandering around this part of San Diego.

Top Otay Mesa Hotel Reviews

The DEXTRO Little Italy, BW Premier Collection

The DEXTRO Little Italy, BW Premier Collection

10/10 Excellent
"I would love to commend all the staffs the service is superb, I would stay again in this hotel quite accessible for public transportation. I also would love to see a microwave next visit and maybe the tubs can be replaced with new ones in the future all in all we had a great time staying with you kids love the pool too!"
Mary Anne 5-night trip
Posted 9 hours ago
The DEXTRO Little Italy, BW Premier Collection

Frequently asked questions

What's it like in Otay Mesa?

Otay Mesa is a neighborhood that travelers like for its beaches, restaurants, and shopping.

Where is the best hotel for a stay in Otay Mesa?

Based on Expedia customer reviews, Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG is the highest ranked property in Otay Mesa. This hotel offers free breakfast and an outdoor pool. Another top choice in the area is Quality Suites San Diego Otay Mesa.

How many hotels will I be able to find in the Otay Mesa area?

Expedia has 5 Otay Mesa hotels and other accommodations, and one might make a good home base for venturing out into the greater San Diego area.

If I need to cancel my hotel reservation in Otay Mesa, will I receive a refund?

Yes! The majority of hotel reservations are fully refundable if you cancel prior to the hotel's cancellation deadline, which in most cases is within 24 or 48 hours of your check-in date. If you have a non-refundable reservation, you might still have the option to cancel and receive a refund within a 24-hour period of booking. Put your dates in and click on "Search", then you can use the "fully refundable" filter to view the best deals available in Otay Mesa.

Where can I learn more about changing or cancelling my trip to Otay Mesa?

To find more details about changing or cancelling your trip to Otay Mesa, go to https://www.expedia.com/service/.

What is there to do in this San Diego neighborhood?

A few places to visit in the area around Otay Mesa include High Performance Center in Tijuana, Parque Industrial FINSA Tijuana, and Otay Sports Fields. While you're out sightseeing, Caliente Casino and Alameda Otay are a couple of additional sights to visit in San Diego.