Otay Mesa, CA

San Diego

A city skyline with high-rise buildings and a bridge over a body of water.
An aerial view of a densely populated city with a mix of residential and commercial buildings, surrounded by greenery and a clear sky.
A hillside town with a winding road, a bridge in the distance, and a river in the foreground.

Stay near popular Otay Mesa attractions


Otay Mesa Hotel Deals

Paradise Point Resort & Spa

Paradise Point Resort & Spa

4 out of 5
1404 Vacation Rd San Diego CA
The price is NT$8,987 per night from Aug 9 to Aug 10
NT$8,987
NT$12,034 total
Aug 9 - Aug 10
includes taxes & fees
Book a stay at this beach resort in San Diego. Enjoy free WiFi, 5 outdoor pools, and a full-service spa. Our guests praise the pool and the helpful staff in ...
8.8/10 Excellent! (2,730 reviews)
"Unexpected $50 nightly per car parking fee and an add on $50 per day resort fee. It's a good place but no longer worth the add on fees."

Reviewed on 2026/7/10

Paradise Point Resort & Spa
Wyndham San Diego Bayside

Wyndham San Diego Bayside

4 out of 5
1355 N Harbor Drive San Diego CA
The price is NT$5,144 per night from Jul 19 to Jul 20
NT$5,144
NT$7,084 total
Jul 19 - Jul 20
includes taxes & fees
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, 3 restaurants, and breakfast (surcharge). Our guests praise the pool and the restaurant ...
8.4/10 Very Good! (6,292 reviews)
"Honestly I was expecting much, much worse based on the reviews I had seen of this hotel so I was pleasantly surprised by most of the staff and the quality of the room. We were given our daily coffee vouchers, we had the same woman every morning and she was absolutely wonderful but I did not catch ..."

Reviewed on 2026/7/10

Wyndham San Diego Bayside
Best Western Seven Seas

Best Western Seven Seas

3 out of 5
411 Hotel Circle South San Diego CA
Fully refundableReserve now, pay when you stay
The price is NT$3,966 per night from Jul 27 to Jul 28
NT$3,966
NT$4,558 total
Jul 27 - Jul 28
includes taxes & fees
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, free parking, and 2 hot tubs. Our guests praise the pool and the restaurant in our ...
8/10 Very Good! (3,712 reviews)
"The Staff is great, every one of them. The grounds are very meticulously maintained by the attentive groundskeepers (who are also very nice). The shower was fantastic! Excellent water pressure 👌 and the food was very good quality 👌 We’ve been here before, and we’ll be back for sure!"

Reviewed on 2026/7/11

Best Western Seven Seas
Hard Rock Hotel San Diego

Hard Rock Hotel San Diego

4 out of 5
207 5th Ave San Diego CA
The price is NT$5,528 per night from Jul 19 to Jul 20
NT$5,528
NT$7,964 total
Jul 19 - Jul 20
includes taxes & fees
Stay at this hotel in San Diego. Enjoy free WiFi, 2 restaurants, and a nightclub. Our guests praise the helpful staff and the convenient parking in our reviews. ...
9/10 Wonderful! (4,028 reviews)
"From the moment we arrived everyone was so helpful and made sure we were taken care of. Everyday we had a fresh clean room, and the staff was always welcoming when we came and left the property. Pool was super nice as well, and the restaurants and bars on site were a major plus as well!"

Reviewed on 2026/7/11

Hard Rock Hotel San Diego
Handlery Hotel

Handlery Hotel

3.5 out of 5
950 Hotel Cir N San Diego CA
The price is NT$4,606 per night from Aug 2 to Aug 3
NT$4,606
NT$5,295 total
Aug 2 - Aug 3
includes taxes & fees
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, 2 restaurants, and 2 bars/lounges. Our guests praise the pool and the helpful staff ...
8.4/10 Very Good! (2,720 reviews)
"When we drove up I was surprised to see it was not a hotel but more like a motel. There are three separate buildings that are more like apartments. When I noticed they were placing us in the second units I asked if there was something else. I was told they were booked to capacity. Went to the room ..."

Reviewed on 2026/7/11

Handlery Hotel
Bahia Resort Hotel

Bahia Resort Hotel

3.5 out of 5
998 W Mission Bay Dr San Diego CA
The price is NT$8,450 per night from Aug 9 to Aug 10
NT$8,450
NT$11,497 total
Aug 9 - Aug 10
includes taxes & fees
Book a stay at this beach resort in San Diego. Enjoy a beach locale, breakfast (surcharge), and 24-hour room service. Our guests praise the pool and the restaurant ...
8.8/10 Excellent! (2,245 reviews)
"Great location family friendly wife loved it"

Reviewed on 2026/7/11

Bahia Resort Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Otay Mesa

Find the best Otay Mesa areas and neighborhoods for the activities you enjoy most.

Downtown San Diego

Petco Park and Seaport Village are a few top attractions in Downtown San Diego. Hop around the city on the metro at Civic Center Station or Civic Center Station and check out the area's fantastic nightlife, fascinating museums, and beautiful waterfront views.

Pacific Beach

The stunning beaches and fantastic nightlife are just a few highlights of Pacific Beach. Make a stop by Mission Bay or Pacific Beach while you're exploring the area.

Mission Beach

If you're spending some time in Mission Beach, Mission Beach and Mission Bay are top sights worth seeing.

Gaslamp Quarter

Fantastic nightlife and popular shops are a few of the things travelers enjoy most about Gaslamp Quarter. A visit to Gaslamp Museum at the Davis-Horton House or Spreckels Theater is also recommended, and you can jump aboard the metro at Gaslamp Quarter Station to get around town.

Mission Bay

If you're spending some time in Mission Bay, Mission Bay and Mission and Pacific Beaches are top sights worth seeing.



Otay Mesa, CA