- Change your mindBook hotels with free cancellation
- Be pickySearch almost a million properties worldwide
Go beyond your typical stay in St. Charles

Pet friendly

Hot tub
Check prices for these dates
Our top choices for St. Charles hotels

1. AmericInn by Wyndham Winona
AmericInn by Wyndham WinonaWinona
9.0 out of 10, Wonderful, (1,000 reviews)
The price is NT$4,390
NT$4,901 total
includes taxes & fees
Dec 4 - Dec 5

2. Hampton Inn Rochester-South
Hampton Inn Rochester-SouthRochester
9.0 out of 10, Wonderful, (1,000 reviews)
The price is NT$3,181
NT$3,662 total
includes taxes & fees
Dec 12 - Dec 13

3. Holiday Inn Express Rochester South - Mayo Area by IHG
Holiday Inn Express Rochester South - Mayo Area by IHGRochester
8.8 out of 10, Excellent, (1,004 reviews)
The price is NT$2,823
NT$3,250 total
includes taxes & fees
Nov 14 - Nov 15

4. Hyatt House Rochester/Mayo Clinic Area
Hyatt House Rochester/Mayo Clinic AreaDowntown Rochester
9.0 out of 10, Wonderful, (1,006 reviews)
The price is NT$3,650
NT$4,202 total
includes taxes & fees
Nov 27 - Nov 28

5. Spark by Hilton Rochester South
Spark by Hilton Rochester SouthRochester
9.2 out of 10, Wonderful, (607 reviews)
The price is NT$2,204
NT$2,537 total
includes taxes & fees
Nov 22 - Nov 23

6. TownePlace Suites by Marriott Rochester Mayo Clinic Area
TownePlace Suites by Marriott Rochester Mayo Clinic AreaKutzky Park
9.6 out of 10, Exceptional, (577 reviews)
The price is NT$4,497
NT$5,177 total
includes taxes & fees
Nov 27 - Nov 28

7. Econo Lodge Mayo Clinic Area
Econo Lodge Mayo Clinic AreaRochester
9.0 out of 10, Wonderful, (1,010 reviews)
The price is NT$2,203
NT$2,536 total
includes taxes & fees
Dec 12 - Dec 13

8. Residence Inn by Marriott Rochester Mayo Clinic Area South
Residence Inn by Marriott Rochester Mayo Clinic Area SouthRochester
9.6 out of 10, Exceptional, (321 reviews)
The price is NT$4,333
NT$4,988 total
includes taxes & fees
Nov 27 - Nov 28

9. La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S
La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic SRochester
7.6 out of 10, Good, (1,063 reviews)
The price is NT$2,344
NT$2,698 total
includes taxes & fees
Nov 15 - Nov 16

10. Home2 Suites by Hilton Rochester Mayo Clinic Area
Home2 Suites by Hilton Rochester Mayo Clinic AreaRochester
9.6 out of 10, Exceptional, (1,003 reviews)
The price is NT$3,655
NT$4,208 total
includes taxes & fees
Nov 29 - Nov 30

11. Comfort Inn & Suites Rochester South Mayo Clinic
Comfort Inn & Suites Rochester South Mayo ClinicRochester
8.8 out of 10, Excellent, (1,009 reviews)
The price is NT$2,466
NT$2,839 total
includes taxes & fees
Dec 12 - Dec 13

12. Fairfield Inn & Suites by Marriott Winona
Fairfield Inn & Suites by Marriott WinonaWinona
9.4 out of 10, Exceptional, (422 reviews)
The price is NT$4,402
NT$4,913 total
includes taxes & fees
Nov 15 - Nov 16

13. Stone Mill Hotel & Suites
Stone Mill Hotel & SuitesLanesboro
9.6 out of 10, Exceptional, (731 reviews)
The price is NT$3,446
NT$3,701 total
includes taxes & fees
Nov 13 - Nov 14

14. Brentwood Inn & Suites
Brentwood Inn & SuitesDowntown Rochester
8.8 out of 10, Excellent, (1,002 reviews)
The price is NT$3,939
NT$4,535 total
includes taxes & fees
Nov 14 - Nov 15

15. Hilton Rochester Mayo Clinic Area
Hilton Rochester Mayo Clinic AreaDowntown Rochester
9.6 out of 10, Exceptional, (657 reviews)
The price is NT$5,552
NT$6,392 total
includes taxes & fees
Nov 27 - Nov 28

16. AmericInn by Wyndham Rochester Near Mayo Clinic
AmericInn by Wyndham Rochester Near Mayo ClinicRochester
8.2 out of 10, Very good, (1,606 reviews)
The price is NT$2,395
NT$2,758 total
includes taxes & fees
Dec 6 - Dec 7

17. Quality Inn & Suites Mayo Clinic Area
Quality Inn & Suites Mayo Clinic AreaRochester
8.8 out of 10, Excellent, (973 reviews)
The price is NT$2,303
NT$2,687 total
includes taxes & fees
Nov 28 - Nov 29

18. SpringHill Suites by Marriott Rochester-Mayo Clinic/St Marys
SpringHill Suites by Marriott Rochester-Mayo Clinic/St MarysKutzky Park
8.6 out of 10, Excellent, (1,000 reviews)
The price is NT$3,372
NT$3,882 total
includes taxes & fees
Dec 6 - Dec 7

19. Holiday Inn Express & Suites Rochester – Mayo Clinic Area by IHG
Holiday Inn Express & Suites Rochester – Mayo Clinic Area by IHGKutzky Park
8.6 out of 10, Excellent, (850 reviews)
The price is NT$3,315
NT$3,817 total
includes taxes & fees
Nov 14 - Nov 15

20. Homewood Suites by Hilton Rochester Mayo Clinic Area / Saint Marys
Homewood Suites by Hilton Rochester Mayo Clinic Area / Saint MarysKutzky Park
9.2 out of 10, Wonderful, (542 reviews)
The price is NT$3,599
NT$4,143 total
includes taxes & fees
Nov 25 - Nov 26
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Compare top hotels in St. Charles
![]() AmericInn by Wyndham WinonaWinona | ![]() Hampton Inn Rochester-SouthRochester | ![]() Holiday Inn Express Rochester South - Mayo Area by IHGRochester | ![]() Hyatt House Rochester/Mayo Clinic AreaDowntown Rochester | ![]() Spark by Hilton Rochester SouthRochester |
|---|---|---|---|---|
9.0 Wonderful 1,000 reviews | 9.0 Wonderful 1,000 reviews | 8.8 Excellent 1,004 reviews | 9.0 Wonderful 1,006 reviews | 9.2 Wonderful 607 reviews |
The price is NT$4,390 NT$4,901 total includes taxes & fees Dec 4 - Dec 5 | The price is NT$3,181 NT$3,662 total includes taxes & fees Dec 12 - Dec 13 | The price is NT$2,823 NT$3,250 total includes taxes & fees Nov 14 - Nov 15 | The price is NT$3,650 NT$4,202 total includes taxes & fees Nov 27 - Nov 28 | The price is NT$2,204 NT$2,537 total includes taxes & fees Nov 22 - Nov 23 |
|
|
|
|
|
Hotels recommended for families in St. Charles
The price is NT$4,390
NT$4,901 total
includes taxes & fees
Dec 4 - Dec 5
Learn more about St. Charles
St. Charles awaits: its natural setting and more!

Top St. Charles Hotel Reviews

Residence Inn by Marriott Rochester Mayo Clinic Area South
Residence Inn by Marriott Rochester Mayo Clinic Area SouthRochester
























































































