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Aug 25 - Aug 26
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Discover San Francisco hotels and places to stay, with room rates, reviews, and availability. Most hotels are fully refundable.

Ramada Plaza By Wyndham Panama Punta Pacífica
Outdoor pool, pool umbrellas, sun loungers

Ramada Plaza By Wyndham Panama Punta Pacífica

4.0 star property
9.6 out of 10, Exceptional, (1023)
"Very nice place and staff"
The price is NT$3,539
NT$3,893 total
includes taxes & fees
Sep 2 - Sep 3
Ramada Plaza By Wyndham Panama Punta Pacífica
Courtyard by Marriott Panama Multiplaza Mall
Reception

Courtyard by Marriott Panama Multiplaza Mall

4.0 star property
8.8 out of 10, Excellent, (1002)
"Good staff, near to the airport"
The price is NT$4,100
NT$4,510 total
includes taxes & fees
Sep 20 - Sep 21
Courtyard by Marriott Panama Multiplaza Mall
Aloft Panama
Exterior

Aloft Panama

3.5 star property
8.6 out of 10, Excellent, (837)
"Nice and convenient location."
The price is NT$3,562
NT$3,919 total
includes taxes & fees
Sep 1 - Sep 2
Aloft Panama
Sheraton Grand Panama
Terrace/patio

Sheraton Grand Panama

4.0 star property
8.6 out of 10, Excellent, (935)
"A great stay. "
The price is NT$4,083
NT$4,491 total
includes taxes & fees
Sep 1 - Sep 2
Sheraton Grand Panama
Boutique Apartments Panamá Coco del Mar
Outdoor pool

Boutique Apartments Panamá Coco del Mar

3.5 star property
7.6 out of 10, Good, (126)
"This is a very good apartment. I felt at home away from home."
The price is NT$998
NT$5,218 total
includes taxes & fees
Aug 27 - Aug 28
Boutique Apartments Panamá Coco del Mar
Megapolis Hotel Panamá
Front of property

Megapolis Hotel Panamá

4.5 star property
8.4 out of 10, Very Good, (1045)
"Had a wonderful stay the staff is very friendly and attentive "
The price is NT$3,868
NT$4,254 total
includes taxes & fees
Sep 14 - Sep 15
Megapolis Hotel Panamá
San Francisco by Wynwood House
Lobby sitting area

San Francisco by Wynwood House

3.5 star property
9.4 out of 10, Exceptional, (44)
"Good comfy rooms"
The price is NT$3,357
NT$4,457 total
includes taxes & fees
Aug 27 - Aug 28
San Francisco by Wynwood House
Plaza Paitilla Inn Hotel
View from property

Plaza Paitilla Inn Hotel

3.5 star property
9.4 out of 10, Exceptional, (2101)
"nice place, good breakfast"
The price is NT$4,814
NT$5,295 total
includes taxes & fees
Aug 27 - Aug 28
Plaza Paitilla Inn Hotel
JW Marriott Panama
4 outdoor pools, free cabanas, pool umbrellas

JW Marriott Panama

5.0 star property
8.8 out of 10, Excellent, (1003)
"Always an exceptional stay. "
The price is NT$7,738
NT$8,512 total
includes taxes & fees
Sep 5 - Sep 6
JW Marriott Panama
Decapolis Hotel Panama City
Exterior

Decapolis Hotel Panama City

4.0 star property
8.6 out of 10, Excellent, (1300)
"Easy to reach and valet parking"
The price is NT$2,893
NT$3,183 total
includes taxes & fees
Sep 5 - Sep 6
Decapolis Hotel Panama City
Residence Inn by Marriott Panama City
Outdoor pool, open 6:00 AM to 11:00 PM, pool umbrellas, sun loungers

Residence Inn by Marriott Panama City

4.0 star property
9.0 out of 10, Wonderful, (502)
"The restaurant has amazing staff! They’re all welcoming and kind and provided fantastic service!"
The price is NT$4,652
NT$5,117 total
includes taxes & fees
Sep 19 - Sep 20
Residence Inn by Marriott Panama City
Las Americas Golden Tower Panama
View from property

Las Americas Golden Tower Panama

4.0 star property
8.8 out of 10, Excellent, (1003)
"Great staff and accommodations "
The price is NT$4,397
NT$4,837 total
includes taxes & fees
Sep 13 - Sep 14
Las Americas Golden Tower Panama
Boutique Apartments Atlapa
Outdoor pool

Boutique Apartments Atlapa

3.0 star property
7.4 out of 10, Good, (18)
"Good"
Boutique Apartments Atlapa
Casa Orquídea
Terrace/patio

Casa Orquídea

2.0 star property
The price is NT$2,721
NT$2,993 total
includes taxes & fees
Sep 8 - Sep 9
Casa Orquídea
w Bright 1BR w Private Balcony in San Francisco
Apartment | Internet

w Bright 1BR w Private Balcony in San Francisco

2.0 star property
The price is NT$2,843
NT$4,032 total
includes taxes & fees
Sep 9 - Sep 10
w Bright 1BR w Private Balcony in San Francisco
w Premium 1BR w Balcony in San Francisco
Apartment | 1 bedroom, Internet

w Premium 1BR w Balcony in San Francisco

2.0 star property
The price is NT$2,917
NT$4,112 total
includes taxes & fees
Sep 9 - Sep 10
w Premium 1BR w Balcony in San Francisco
Crowne Plaza Panama Airport by IHG
Outdoor pool, pool umbrellas, sun loungers

Crowne Plaza Panama Airport by IHG

4.0 star property
8.4 out of 10, Very Good, (2198)
"I love how convenient it is for people to get to the hotel , the food was great , service was great too! "
The price is NT$3,471
NT$3,818 total
includes taxes & fees
Sep 11 - Sep 12
Crowne Plaza Panama Airport by IHG
Central Hotel Panama Casco Viejo
47-inch flat-screen TV with cable channels, TV

Central Hotel Panama Casco Viejo

4.0 star property
9.0 out of 10, Wonderful, (976)
"The hotel is beautiful and in perfect location. On site staff was very friendly and helpful. Would definitely stay here again."
The price is NT$5,156
NT$5,671 total
includes taxes & fees
Sep 1 - Sep 2
Central Hotel Panama Casco Viejo
The Westin Playa Bonita Panama
3 outdoor pools, pool umbrellas, sun loungers

The Westin Playa Bonita Panama

5.0 star property
8.0 out of 10, Very Good, (1005)
"Excelente hotel. "
The price is NT$4,689
NT$5,158 total
includes taxes & fees
Sep 21 - Sep 22
The Westin Playa Bonita Panama
Hotel Riu Plaza Panama
Outdoor pool, sun loungers

Hotel Riu Plaza Panama

5.0 star property
9.0 out of 10, Wonderful, (4201)
"Very convenient location, friendly staff and all around beautiful hotel."
The price is NT$3,324
NT$3,656 total
includes taxes & fees
Aug 27 - Aug 28
Hotel Riu Plaza Panama
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Where to stay in San Francisco

Find the best San Francisco areas and neighborhoods for the activities you enjoy most.

Casco Viejo

Unique features of Casco Viejo include the historic sites and bars. Make a stop by Metropolitan Cathedral of Panama or Interoceanic Canal Museum while you're exploring the area.

Bella Vista

Bella Vista is highly notable for its popular shops, and you might want to visit top sights like Via Espana and Iglesia del Carmen. See more of Panama City by jumping on the metro at Iglesia del Carmen Station or Vía Argentina.

El Cangrejo

The abundant dining options and casinos are top of the list for many visitors to El Cangrejo. A stop by Crown Casino or Luxor Towers might round out your trip.

Punta Paitilla

1 out of top 10 points of interest in this area

Travelers come to Punta Paitilla for its abundant dining options, and you can see top attractions like Avenida Balboa and Multicentro Panama while you're in town.

Calidonia

1 out of top 10 points of interest in this area

You might enjoy the shopping while in Calidonia. Cinta Costera is a notable sight, and you can get around town at Estación Lotería or Santo Tomas Station to see more of the city.

Top San Francisco Hotel Reviews

Explore a world of travel with Expedia

Explore a world of travel with Expedia

Frequently asked questions

What is San Francisco like?

San Francisco is a welcoming neighborhood that travelers like for its restaurants. Be sure to check out Multiplaza Pacific Mall and Calle 50 as part of your San Francisco travel plans.

Where is the best hotel for a stay in San Francisco?

Based on Expedia customer reviews, Ramada Plaza By Wyndham Panama Punta Pacífica is the highest ranked property in San Francisco. This hotel is a short 4-minute walk from Multiplaza Pacific Mall, and it offers free breakfast and a restaurant. Other top choices in the neighborhood include Plaza Paitilla Inn Hotel and Decapolis Hotel Panama City.

How many hotels will I find in San Francisco?

If you're searching for places to stay in Panama City, Expedia has something to meet your needs with 224 San Francisco hotels and other accommodations to choose from.

If I need to cancel my hotel reservation in San Francisco, will I receive a refund?

Yes! Most room reservations are fully refundable if you cancel prior to the hotel's cancellation deadline, which often is within 24-48 hours of the scheduled arrival. If you have a non-refundable reservation, you might be able to cancel it and receive a refund within a 24-hour period of booking. Add dates, click "Search", then use the "fully refundable" filter to get top deals in San Francisco.

Where can I learn more about changing or cancelling my trip to San Francisco?

For additional details about updating your trip to San Francisco or cancelling it, head over to our customer service page.

What is there to do in this Panama City neighborhood?

While you're in San Francisco, a shopping trip to Multiplaza Pacific Mall, Avenida Balboa, or Pacific Center, might be the perfect place to find that souvenir you've been looking for. Calle 50 and Panama Canal Murals are some other stops to visit in the neighborhood. A few places to visit in the area around San Francisco include Colonial Religious Art Museum, Bingo 90, and Soho City Center. When you're sightseeing in Panama City, National Shrine of the Heart of Mary and Panama Viejo Museum are also worth a stop.