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Find hotels in San Francisco, Panama City from NT$898

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Discover 1,543 San Francisco hotels and places to stay, with room rates, reviews, and availability. Most hotels are fully refundable.

Our top choices for San Francisco hotels

Ramada Plaza By Wyndham Panama Punta Pacífica
Outdoor pool, pool umbrellas, sun loungers

Ramada Plaza By Wyndham Panama Punta Pacífica

4.0 star property
9.6 out of 10, Exceptional, (1032)
"Family-friendly hotel, tasty breakfast options daily and overall friendly staff and clean space."
The price is NT$3,209
NT$3,530 total
includes taxes & fees
Oct 9 - Oct 10
Ramada Plaza By Wyndham Panama Punta Pacífica
Aloft Panama
Exterior

Aloft Panama

3.5 star property
8.6 out of 10, Excellent, (844)
"The buffet breakfast was excellent and staff was very friendly. "
The price is NT$3,576
NT$3,933 total
includes taxes & fees
Sep 15 - Sep 16
Aloft Panama
Courtyard by Marriott Panama Multiplaza Mall
Reception

Courtyard by Marriott Panama Multiplaza Mall

4.0 star property
8.8 out of 10, Excellent, (1003)
"It was in the moddle of the town very nice surroundings "
The price is NT$3,961
NT$4,357 total
includes taxes & fees
Oct 4 - Oct 5
Courtyard by Marriott Panama Multiplaza Mall
Sheraton Grand Panama
Terrace/patio

Sheraton Grand Panama

4.0 star property
8.6 out of 10, Excellent, (943)
"Great staff and beautiful hotel. Will definitely stay again!"
The price is NT$4,098
NT$4,508 total
includes taxes & fees
Sep 14 - Sep 15
Sheraton Grand Panama
Boutique Apartments Panamá Coco del Mar
Outdoor pool

Boutique Apartments Panamá Coco del Mar

3.5 star property
7.6 out of 10, Good, (128)
"Great view with access to the pool and gym."
The price is NT$898
NT$5,122 total
includes taxes & fees
Sep 9 - Sep 10
Boutique Apartments Panamá Coco del Mar
Megapolis Hotel Panamá
Front of property

Megapolis Hotel Panamá

4.5 star property
8.4 out of 10, Very Good, (1067)
"Had a wonderful stay the staff is very friendly and attentive "
The price is NT$3,882
NT$4,271 total
includes taxes & fees
Sep 27 - Sep 28
Megapolis Hotel Panamá
Plaza Paitilla Inn Hotel
View from property

Plaza Paitilla Inn Hotel

3.5 star property
9.4 out of 10, Exceptional, (2108)
"nice place, good breakfast"
The price is NT$4,832
NT$5,315 total
includes taxes & fees
Sep 10 - Sep 11
Plaza Paitilla Inn Hotel
JW Marriott Panama
4 outdoor pools, free cabanas, pool umbrellas

JW Marriott Panama

5.0 star property
8.8 out of 10, Excellent, (1004)
"Great stay"
The price is NT$6,988
NT$7,687 total
includes taxes & fees
Sep 19 - Sep 20
JW Marriott Panama
San Francisco by Wynwood House
Lobby sitting area

San Francisco by Wynwood House

3.0 star property
9.4 out of 10, Exceptional, (47)
"Good comfy rooms"
The price is NT$2,949
NT$4,008 total
includes taxes & fees
Sep 14 - Sep 15
San Francisco by Wynwood House
Decapolis Hotel Panama City
Exterior

Decapolis Hotel Panama City

4.0 star property
8.6 out of 10, Excellent, (1307)
"Free internet, breakfast options nice and tasty"
The price is NT$2,904
NT$3,195 total
includes taxes & fees
Sep 12 - Sep 13
Decapolis Hotel Panama City
Las Americas Golden Tower Panama
View from property

Las Americas Golden Tower Panama

4.0 star property
9.0 out of 10, Wonderful, (1005)
"Great staff and accommodations "
The price is NT$4,904
NT$5,395 total
includes taxes & fees
Sep 13 - Sep 14
Las Americas Golden Tower Panama
Residence Inn by Marriott Panama City
Outdoor pool, open 6:00 AM to 11:00 PM, pool umbrellas, sun loungers

Residence Inn by Marriott Panama City

4.0 star property
9.0 out of 10, Wonderful, (508)
"Great location. "
The price is NT$4,130
NT$4,543 total
includes taxes & fees
Oct 3 - Oct 4
Residence Inn by Marriott Panama City
Boutique Apartments Atlapa
Outdoor pool

Boutique Apartments Atlapa

3.0 star property
7.2 out of 10, Good, (19)
"Buen lugar para estar por unos días en Panamá"
Boutique Apartments Atlapa
Casa Orquídea
Terrace/patio

Casa Orquídea

2.0 star property
8.0 out of 10, Very Good, (1)
"For me was very convenient "
The price is NT$2,720
NT$2,992 total
includes taxes & fees
Sep 19 - Sep 20
Casa Orquídea
w Bright 1BR w Private Balcony in San Francisco
Apartment | Internet

w Bright 1BR w Private Balcony in San Francisco

2.0 star property
w Bright 1BR w Private Balcony in San Francisco
w Premium 1BR w Balcony in San Francisco
Apartment | 1 bedroom, Internet

w Premium 1BR w Balcony in San Francisco

2.0 star property
The price is NT$3,074
NT$4,289 total
includes taxes & fees
Sep 21 - Sep 22
w Premium 1BR w Balcony in San Francisco
Wanders Panama by Boutique Apartments
Outdoor pool

Wanders Panama by Boutique Apartments

4.0 star property
The price is NT$3,851
NT$7,564 total
includes taxes & fees
Sep 21 - Sep 22
Wanders Panama by Boutique Apartments
Crowne Plaza Panama Airport by IHG
Outdoor pool, pool umbrellas, sun loungers

Crowne Plaza Panama Airport by IHG

4.0 star property
8.4 out of 10, Very Good, (2213)
"Great hotel near the airport "
The price is NT$3,790
NT$4,169 total
includes taxes & fees
Sep 28 - Sep 29
Crowne Plaza Panama Airport by IHG
Central Hotel Panama Casco Viejo
47-inch flat-screen TV with cable channels, TV

Central Hotel Panama Casco Viejo

4.0 star property
9.0 out of 10, Wonderful, (988)
"The hotel is so beautiful, the people are very friendly and helpful!"
The price is NT$5,023
NT$5,525 total
includes taxes & fees
Sep 9 - Sep 10
Central Hotel Panama Casco Viejo
Hotel Riu Plaza Panama
Outdoor pool, sun loungers

Hotel Riu Plaza Panama

5.0 star property
9.0 out of 10, Wonderful, (4249)
"Excelente Hotel en todos sus aspectos. "
The price is NT$3,342
NT$3,676 total
includes taxes & fees
Sep 9 - Sep 10
Hotel Riu Plaza Panama
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in San Francisco

Find the best San Francisco areas and neighborhoods for the activities you enjoy most.

Casco Viejo

Unique features of Casco Viejo include the historic sites and bars. Make a stop by Interoceanic Canal Museum or National Theater while you're exploring the area.

Bella Vista

Bella Vista is highly notable for its popular shops, and you might want to visit top sights like Via Espana and Iglesia del Carmen. See more of Panama City by jumping on the metro at Iglesia del Carmen Station or Vía Argentina.

El Cangrejo

The abundant dining options and casinos are top of the list for many visitors to El Cangrejo. A stop by Crown Casino or Luxor Towers might round out your trip.

Punta Paitilla

1 out of top 10 points of interest in this area

Travelers come to Punta Paitilla for its abundant dining options, and you can see top attractions like Avenida Balboa and Multicentro Panama while you're in town.

Calidonia

1 out of top 10 points of interest in this area

You might enjoy the shopping while in Calidonia. Cinta Costera is a notable sight, and you can get around town at Estación Lotería or Santo Tomas Station to see more of the city.

Top San Francisco Hotel Reviews

Hotel Riu Plaza Panama

Hotel Riu Plaza Panama

10/10 Excellent
"I love the frie"
shacody 4-night trip
Posted 17 hours ago
Hotel Riu Plaza Panama
Megapolis Hotel Panamá

Megapolis Hotel Panamá

10/10 Excellent
"Lit "
Dwayne 6-night trip
Posted 13 days ago
Megapolis Hotel Panamá

Explore a world of travel with Expedia

Explore a world of travel with Expedia

Frequently asked questions

What is San Francisco like?

San Francisco is a welcoming neighborhood that travelers like for its restaurants. Be sure to check out Multiplaza Pacific Mall and Calle 50 as part of your San Francisco travel plans.

Where is the best hotel for a stay in San Francisco?

Based on Expedia customer reviews, Ramada Plaza By Wyndham Panama Punta Pacífica is the highest ranked property in San Francisco. This hotel is a short 4-minute walk from Multiplaza Pacific Mall, and it offers free breakfast and a restaurant. Other top choices in the neighborhood include Plaza Paitilla Inn Hotel and Residence Inn by Marriott Panama City.

How many hotels will I find in San Francisco?

If you're searching for places to stay in Panama City, Expedia has something to meet your needs with 215 San Francisco hotels and other accommodations to choose from.

If I need to cancel my hotel reservation in San Francisco, will I receive a refund?

Yes! Most room reservations are fully refundable if you cancel prior to the hotel's cancellation deadline, which often is within 24-48 hours of the scheduled arrival. If you have a non-refundable reservation, you might be able to cancel it and receive a refund within a 24-hour period of booking. Add dates, click "Search", then use the "fully refundable" filter to get top deals in San Francisco.

Where can I learn more about changing or cancelling my trip to San Francisco?

For additional details about updating your trip to San Francisco or cancelling it, head over to our customer service page.

What is there to do in this Panama City neighborhood?

While you're in San Francisco, a shopping trip to Multiplaza Pacific Mall, Avenida Balboa, or Pacific Center, might be the perfect place to find that souvenir you've been looking for. Calle 50 and Panama Canal Murals are some other stops to visit in the neighborhood. A few places to visit in the area around San Francisco include Colonial Religious Art Museum, Bingo 90, and Soho City Center. When you're sightseeing in Panama City, National Shrine of the Heart of Mary and Panama Viejo Museum are also worth a stop.