
Panama City Vacations
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Where to stay in Panama City
Find the best Panama City areas and neighborhoods for the activities you enjoy most. Learn more about Panama City

Casco Viejo
4.5/5(178 area reviews)
Unique features of Casco Viejo include the historic sites and bars. Make a stop by Metropolitan Cathedral of Panama or Interoceanic Canal Museum while you're exploring the area.
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Panama City Hotel Deals

Hotel Riu Plaza Panama
Calle 50, Urb. Marbella, Panama City, Panama
Fully refundableReserve now, pay when you stay
The price is NT$3,745 per night from Aug 25 to Aug 26
NT$3,745
NT$4,120 total
Aug 25 - Aug 26
includes taxes & fees
9/10 Wonderful! (4,138 reviews)
"Staff is friendly. Pool bar has a great atmosphere..the nachos are delicious. The suite was awesome! Well worth it. Fast Uber service."
Reviewed on 2025/8/6

Sheraton Grand Panama
Via Israel And 77th Street, Panama City, Panama
Fully refundableReserve now, pay when you stay
The price is NT$4,013 per night from Aug 15 to Aug 16
NT$4,013
NT$4,414 total
Aug 15 - Aug 16
includes taxes & fees
8.4/10 Very Good! (918 reviews)
"Great service! Clean, easy to move around. Close to multiplaza. Great for families"
Reviewed on 2025/8/4

Waymore Hotel Spa & Casino
Calle Augusto Samuel Boyd y Calle Eusebi, Panama City
Fully refundableReserve now, pay when you stay
The price is NT$2,397 per night from Aug 14 to Aug 15
NT$2,397
NT$2,637 total
Aug 14 - Aug 15
includes taxes & fees
9/10 Wonderful! (391 reviews)
"Awesome"
Reviewed on 2025/8/6
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Discover the most popular places to visit in Panama City

Miraflores Locks
Learn about the local history of Ancon with a stop at Miraflores Locks. Visit the casinos and shops in this vibrant area.
Amador Convention Center
Learn about the events happening at Amador Convention Center during your trip to Ancon. While in this walkable area, you can savor the top-notch restaurants.
Frequently asked questions
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Packages
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.