Panama City Vacations

Book a Hotel + Flight or Car together to unlock savings

  • Plan, book, travel with confidence

  • Better together

    Save up to NT$25,000 when you book a flight and hotel together*

  • Find the right fit

    With over 300,000 hotels worldwide, it's easy to create a perfect package

  • Rest easy

    Plan, book, and manage your trip all in one place

Where to stay in Panama City

Find the best Panama City areas and neighborhoods for the activities you enjoy most. Learn more about Panama City
A waterfront cityscape with historic buildings and a prominent clock tower.

Casco Viejo

Unique features of Casco Viejo include the historic sites and bars. Make a stop by Independence Square or Interoceanic Canal Museum while you're exploring the area.

Find hotels in Casco Viejo

Find the Best Panama City Vacation Packages

Panama City Hotel Deals

Hotel Riu Plaza Panama

Hotel Riu Plaza Panama

5 out of 5
Calle 50, Urb. Marbella Panama City Panama
Fully refundableReserve now, pay when you stay
The price is NT$4,858 per night from Jul 19 to Jul 20
NT$4,858
NT$5,344 total
Jul 19 - Jul 20
includes taxes & fees
9/10 Wonderful! (5,738 reviews)
"My 23rd Floor had water damage and smelled like mildew."

Reviewed on 2026/7/15

Hotel Riu Plaza Panama
Megapolis Hotel Panamá

Megapolis Hotel Panamá

4.5 out of 5
Avenida Balboa Panama City
The price is NT$4,780 per night from Aug 3 to Aug 4
NT$4,780
NT$5,258 total
Aug 3 - Aug 4
includes taxes & fees
8.4/10 Very Good! (1,598 reviews)
"Rooms were immaculate, breakfast was great every morning. Cleaning was strange. I place my bag in the closet and the maid cleaned that out. I put in the closet to be safe, it WAS NOT."

Reviewed on 2026/7/14

Megapolis Hotel Panamá
Waldorf Astoria Panama

Waldorf Astoria Panama

5 out of 5
47th St. & Uruguay Street Panama City Panama
Fully refundableReserve now, pay when you stay
The price is NT$8,854 per night from Aug 14 to Aug 15
NT$8,854
NT$9,740 total
Aug 14 - Aug 15
includes taxes & fees
9/10 Wonderful! (1,002 reviews)
"Convenient location and a wonderful staff. Very friendly and helpful. The hotel is modern with good amenities."

Reviewed on 2026/7/8

Waldorf Astoria Panama
See all 1,634 properties in Panama City
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Stay near popular Panama City attractions

A modern building facade with vertical reflective panels and the word "GUCCI" prominently displayed.
Photo by Fabiola Tile
Open Photo by Fabiola Tile

Multiplaza Pacific Mall

9.0/10 (4,497 reviews)
Panama's premier shopping destination houses over 500 stores, from luxury brands like Gucci to popular retailers like Apple. Obtain the Panama Shopping Card at reception for exclusive discounts throughout the mall.
See properties

Frequently asked questions

How much does a Panama City vacation package cost?
You can pick up a vacation package to this destination on Expedia. However, how much your vacation to Panama City costs will depend on factors like your hotel choice, length of stay and season.
What are the cheapest months to go to Panama City?
You're likely to find lower rates and better availability in September, October and November. Take a look at our cheap Panama City vacation packages and you could get some great off-season discounts.
How many days is enough for Panama City?
Dedicate around 3 days for your Panama City vacation in order to discover everything that makes this destination special. Stroll around popular areas, including San Francisco and Campo Alegre. Then check out major sights such as Metropolitan Cathedral of Panama and National Theater. With a good itinerary, you can keep busy with room for some rest time too. Want to travel beyond Panama City? Consider squeezing in an excursion or two.
Is it worth booking a vacation package to Panama City?
Popular for its nature, nightlife and culture, a Panama City vacation is a hit with all types of travelers. Be sure to visit leading sights like Albrook Shopping Mall and Cinta Costera, and consider renting a car for day trips to explore even more.
How to find the best Panama City package deals?
Landing a cheap Panama City package deal is a cinch with Expedia. After you've entered your destination and travel dates under our "Packages" tab, set your budget range, add some filters and browse what's available. You can tweak your search by "Amenities," "Property type," "Traveler experience" and more. Sort the results by "Price: low to high" to view the most wallet-friendly Panama City package deals. Want a simple trick to get the biggest savings? Be flexible with your departure dates and consider traveling on a weekday, when prices are typically lower.
Is it cheaper to book a Panama City vacation as a package?
You can enjoy significant savings on your Panama City getaway by booking a personalized vacation package. Click on the "Package" heading, then select your travel dates and destination to see the best hotel and flight prices. Bundle everything into a great-value package and you can save hundreds of dollars. Consider adding a car rental and you may score a better deal.
When to book a vacation package to Panama City?
Enjoy incredible discounts by booking your flights early with Expedia. If spontaneity is more your style, take advantage of our last-minute deals for a spur-of-the-moment Panama City trip.
How to plan a trip to Panama City?

  1. Choose when to go: Check your schedule and get your bags packed. Your preferred time of year and the available activities will also help you decide when to visit Panama City.
  2. Plan your budget wisely: As well as the cost of your stay, you'll need to factor in other expenses too. These include food, flights and transportation. Also, put aside a little extra for unexpected costs that could arise during your trip to Panama City.
  3. Work out your trip length: Think about how long you want to spend exploring Panama City. Plan your itinerary so you can get to all the attractions and activities you're interested in at a leisurely pace.
  4. Bundle your bookings: With your travel dates in order, you can combine your car rental, hotels, flights and more into a customized Panama City vacation package.

Explore a world of travel with Expedia

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.