What's it like in Illinois Medical District?

Guests are sure to enjoy their time checking out all that Chicago's Illinois Medical District neighborhood has to offer.

Where is the best place to stay in Illinois Medical District?

Based on Expedia customer reviews, Hampton Inn & Suites Chicago Medical District UIC is the highest ranked property in Illinois Medical District. This hotel is a short 15-minute walk from United Center, and it offers free breakfast and an indoor pool. Other top choices in the neighborhood include Hyatt House Chicago Medical/University District and Hyatt Place Chicago Medical/University District .

How many hotels are there in the Illinois Medical District area?

Expedia has 9 Illinois Medical District hotels and other accommodations, and one might make a good home base for venturing out into the greater Chicago area.

If I need to cancel my hotel reservation in Illinois Medical District, will I receive a refund?

Yes! Most hotel reservations are refundable provided that you cancel before the hotel’s cancellation deadline, which often is within 24-48 hours of your arrival date. If you booked a non-refundable reservation, you might be able to still cancel and be given a refund within a 24-hour period of booking. Add dates, click "Search", then use the "fully refundable" filter to review the best options available in Illinois Medical District.

Where can I learn more about changing or cancelling my trip to Illinois Medical District?

To access more information about changing or cancelling your trip to Illinois Medical District, head over to our customer service page .

What can I see and do in this Chicago neighborhood?

Don't miss favorite places to visit in the surrounding area, such as Michigan Avenue, United Center, and Soldier Field. Malcolm X College and Michael Jordan Statue are also worth a visit when you're out sightseeing in Chicago.

How can I get around Illinois Medical District and the greater Chicago area?

Ready to get out and explore the city? Polk Station (Pink Line) is the closest metro station.

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Dates

April 2026

May 2026

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Our top choices for Illinois Medical District hotels

Hyatt House Chicago Medical/University District

Illinois Medical District

Shartina

NT$5,396 total

includes taxes & fees

Mar 31 - Apr 1

Hampton Inn & Suites Chicago Medical District UIC

Illinois Medical District

Jonathon

NT$5,263 total

includes taxes & fees

Mar 22 - Mar 23

Hyatt Place Chicago Medical/University District

Illinois Medical District

Jason Matthew

NT$5,208 total

includes taxes & fees

Apr 5 - Apr 6

Sable at Navy Pier Chicago, Curio Collection by Hilton

Streeterville, 6.4 km from Illinois Medical District

Kimberly

NT$6,545 total

includes taxes & fees

Mar 24 - Mar 25

The Wade

Streeterville, 5.6 km from Illinois Medical District

Shari

NT$4,834 total

includes taxes & fees

Mar 31 - Apr 1

Hilton Chicago/Magnificent Mile Suites

Streeterville, 5.6 km from Illinois Medical District

Michael

NT$4,578 total

includes taxes & fees

Mar 29 - Mar 30

Hotel Riu Plaza Chicago

Streeterville, 5.1 km from Illinois Medical District

Bianca

NT$5,866 total

includes taxes & fees

Mar 24 - Mar 25

55-inch LCD TV with cable channels, TV, pay movies

L7 Chicago by LOTTE

Theatre District, 4.5 km from Illinois Medical District

Maureen

NT$6,374 total

includes taxes & fees

Mar 31 - Apr 1

River Hotel

The Loop, 4.6 km from Illinois Medical District

Ciandra

NT$3,695 total

includes taxes & fees

Mar 31 - Apr 1

Hyatt Centric The Loop Chicago

Theatre District, 3.9 km from Illinois Medical District

eduardo

NT$6,054 total

includes taxes & fees

Mar 20 - Mar 21

Hyatt Regency Chicago

The Loop, 4.8 km from Illinois Medical District

Renae

NT$6,691 total

includes taxes & fees

Apr 5 - Apr 6

Swissotel - Chicago

5 km from Illinois Medical District

Natalie

NT$5,950 total

includes taxes & fees

Mar 29 - Mar 30

Pendry Chicago

Theatre District, 4.6 km from Illinois Medical District

karina

NT$8,431 total

includes taxes & fees

Apr 12 - Apr 13

Congress Plaza Hotel

The Loop, 4.2 km from Illinois Medical District

Jennifer

NT$6,059 total

includes taxes & fees

Mar 27 - Mar 28

Fairmont Chicago at Millennium Park

The Loop, 4.8 km from Illinois Medical District

laila

NT$7,462 total

includes taxes & fees

Mar 29 - Mar 30

Palmer House a Hilton Hotel

Theatre District, 4.2 km from Illinois Medical District

Krista

NT$5,859 total

includes taxes & fees

Apr 5 - Apr 6

DoubleTree by Hilton Chicago - Magnificent Mile

Streeterville, 5.3 km from Illinois Medical District

Ellen

NT$4,271 total

includes taxes & fees

Mar 29 - Mar 30

Aloft Chicago Mag Mile

Streeterville, 5.2 km from Illinois Medical District

Taneshia

NT$4,062 total

includes taxes & fees

Mar 22 - Mar 23

Club Quarters Hotel Wacker at Michigan, Chicago

The Loop, 4.6 km from Illinois Medical District

Michael

NT$3,695 total

includes taxes & fees

Mar 31 - Apr 1

Silversmith Hotel Chicago Downtown

Theatre District, 4.2 km from Illinois Medical District

Bradford

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Where to stay in Illinois Medical District

Find the best Illinois Medical District areas and neighborhoods for the activities you enjoy most.

Downtown Chicago

The heart of the Midwest’s glittering metropolis has many offerings, from shopping and dining to parks, museums and exciting contemporary public art.

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Magnificent Mile

Upscale shopping district with luxury department stores, boutiques, and acclaimed restaurants, featuring landmarks like the Wrigley Building and Chicago Water Tower. The Magnificent Mile is easily accessible by public transit and seasonal trolley service.

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The Loop

Chicago's central business district boasts numerous global businesses, retail establishments, and theaters. Explore the Loop Retail Historic District, Chicago Landmark Historic Michigan Boulevard District, and visit iconic attractions like the Art Institute of Chicago.

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River North

Artistic spirit thrives here, with art galleries and a design district featuring luxury interior furnishings. Explore Kingsbury Park, enjoy vibrant nightlife on Hubbard Street, and visit the iconic Contemporaine Building.

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Lincoln Park

Upscale national retailers, boutiques, and bookstores abound in this affluent area, alongside numerous restaurants and coffee shops. Must-see attractions include Lincoln Park Zoo, Chicago History Museum, and North Avenue Beach. Easily accessible via CTA transit and major roads.

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Top Illinois Medical District Hotel Reviews

Embassy Suites by Hilton Chicago Downtown River North

6/10 Okay

"Overall, the hotel itself was good. The housekeeping staff was not responsive, and did not replenish items even after requesting three times in 24 hours. Very frustrating at this level of hotel."