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Our top choices for Illinois Medical District hotels

Hyatt House Chicago Medical/University District

Hyatt House Chicago Medical/University District
3.5 star property
Illinois Medical District
9.0 out of 10, Wonderful, (1,452 reviews)
"Breakfast was very good, staff friendly, location was nice "
United States
Shartina
The price is NT$4,596
NT$5,396 total
includes taxes & fees
Mar 31 - Apr 1
Hyatt House Chicago Medical/University District

Hampton Inn & Suites Chicago Medical District UIC

Hampton Inn & Suites Chicago Medical District UIC
2.5 star property
Illinois Medical District
9.6 out of 10, Exceptional, (516 reviews)
"Great stay!"
United States
Jonathon
The price is NT$4,466
NT$5,243 total
includes taxes & fees
Mar 22 - Mar 23
Hampton Inn & Suites Chicago Medical District UIC

Hyatt Place Chicago Medical/University District

Hyatt Place Chicago Medical/University District
3.0 star property
Illinois Medical District
9.0 out of 10, Wonderful, (1,495 reviews)
"It was a nice place to stay near United Center."
United States
Jason Matthew
The price is NT$4,437
NT$5,208 total
includes taxes & fees
Apr 5 - Apr 6
Hyatt Place Chicago Medical/University District

Sable at Navy Pier Chicago, Curio Collection by Hilton

Sable at Navy Pier Chicago, Curio Collection by Hilton
4.0 star property
Streeterville, 6.4 km from Illinois Medical District
9.4 out of 10, Exceptional, (2,410 reviews)
"Great stay! I will stay here again on my next trip back this summer!"
United States
Letisha
The price is NT$4,646
NT$6,545 total
includes taxes & fees
Mar 24 - Mar 25
Sable at Navy Pier Chicago, Curio Collection by Hilton

The Wade

The Wade
4.5 star property
Streeterville, 5.6 km from Illinois Medical District
8.4 out of 10, Very Good, (1,732 reviews)
"Loved this hotel, i will be back"
United States
Shari
The price is NT$4,118
NT$4,834 total
includes taxes & fees
Mar 31 - Apr 1
The Wade

Hilton Chicago/Magnificent Mile Suites

Hilton Chicago/Magnificent Mile Suites
3.5 star property
Streeterville, 5.6 km from Illinois Medical District
9.0 out of 10, Wonderful, (3,931 reviews)
"Great hotel great location. "
United States
Michael
The price is NT$3,900
NT$4,578 total
includes taxes & fees
Mar 25 - Mar 26
Hilton Chicago/Magnificent Mile Suites

Hotel Riu Plaza Chicago

Hotel Riu Plaza Chicago
4.0 star property
Streeterville, 5.1 km from Illinois Medical District
9.4 out of 10, Exceptional, (3,558 reviews)
"Great location ans staff was amazing!!"
United States
Bianca
The price is NT$4,212
NT$5,844 total
includes taxes & fees
Mar 24 - Mar 25
Hotel Riu Plaza Chicago

L7 Chicago by LOTTE

L7 Chicago by LOTTE
4.5 star property
Theatre District, 4.5 km from Illinois Medical District
9.6 out of 10, Exceptional, (3,786 reviews)
"Amazing hotel-- Loved staying here."
United States
Maureen
The price is NT$5,430
NT$6,374 total
includes taxes & fees
Mar 31 - Apr 1
L7 Chicago by LOTTE

River Hotel

River Hotel
4.0 star property
The Loop, 4.6 km from Illinois Medical District
8.8 out of 10, Excellent, (5,021 reviews)
"very beautiful hotel and great location "
United States
Ciandra
The price is NT$3,073
NT$3,608 total
includes taxes & fees
Apr 1 - Apr 2
River Hotel

Hyatt Centric The Loop Chicago

Hyatt Centric The Loop Chicago
4.0 star property
Theatre District, 3.9 km from Illinois Medical District
9.0 out of 10, Wonderful, (2,415 reviews)
"this location is safe and convenient-would book here again."
United States
eduardo
The price is NT$4,477
NT$6,054 total
includes taxes & fees
Mar 20 - Mar 21
Hyatt Centric The Loop Chicago

Hyatt Regency Chicago

Hyatt Regency Chicago
4.0 star property
The Loop, 4.8 km from Illinois Medical District
9.4 out of 10, Exceptional, (3,478 reviews)
"Great stay! Wonderful location!"
United States
Renae
The price is NT$4,721
NT$6,666 total
includes taxes & fees
Apr 5 - Apr 6
Hyatt Regency Chicago

Swissotel - Chicago

Swissotel - Chicago
4.5 star property
5 km from Illinois Medical District
9.0 out of 10, Wonderful, (3,219 reviews)
"Helpful staff, great location with views, restaurant and bar on-site"
United States
Natalie
The price is NT$4,111
NT$5,950 total
includes taxes & fees
Mar 29 - Mar 30
Swissotel - Chicago

Pendry Chicago

Pendry Chicago
4.5 star property
Theatre District, 4.6 km from Illinois Medical District
9.4 out of 10, Exceptional, (1,131 reviews)
"Great location, clean and very nice restaurant and bar. "
United States
karina
The price is NT$6,065
NT$8,431 total
includes taxes & fees
Apr 12 - Apr 13
Pendry Chicago

Congress Plaza Hotel

Congress Plaza Hotel
3.5 star property
The Loop, 4.2 km from Illinois Medical District
8.0 out of 10, Very Good, (9,968 reviews)
"Great location, beautiful historic hotel with clean, updated rooms. "
United States
Jennifer
The price is NT$3,459
NT$4,060 total
includes taxes & fees
Apr 1 - Apr 2
Congress Plaza Hotel

Fairmont Chicago at Millennium Park

Fairmont Chicago at Millennium Park
4.5 star property
The Loop, 4.8 km from Illinois Medical District
8.6 out of 10, Excellent, (2,083 reviews)
"amazing stay 10/10 would recommend "
United States
laila
The price is NT$5,399
NT$7,462 total
includes taxes & fees
Mar 29 - Mar 30
Fairmont Chicago at Millennium Park

Palmer House a Hilton Hotel

Palmer House a Hilton Hotel
4.0 star property
Theatre District, 4.2 km from Illinois Medical District
8.6 out of 10, Excellent, (2,334 reviews)
"We had a great stay and the staff are very friendly and accommodating. "
United States
Krista
The price is NT$4,309
NT$5,859 total
includes taxes & fees
Apr 5 - Apr 6
Palmer House a Hilton Hotel

DoubleTree by Hilton Chicago - Magnificent Mile

DoubleTree by Hilton Chicago - Magnificent Mile
4.0 star property
Streeterville, 5.3 km from Illinois Medical District
8.8 out of 10, Excellent, (2,360 reviews)
"Loved this hotel!"
United States
Ellen
The price is NT$3,638
NT$4,271 total
includes taxes & fees
Mar 25 - Mar 26
DoubleTree by Hilton Chicago - Magnificent Mile

Aloft Chicago Mag Mile

Aloft Chicago Mag Mile
3.0 star property
Streeterville, 5.2 km from Illinois Medical District
8.6 out of 10, Excellent, (3,137 reviews)
"Nice location and good hotel"
United States
Taneshia
The price is NT$3,639
NT$4,272 total
includes taxes & fees
Mar 22 - Mar 23
Aloft Chicago Mag Mile

Club Quarters Hotel Wacker at Michigan, Chicago

Club Quarters Hotel Wacker at Michigan, Chicago
4.0 star property
The Loop, 4.6 km from Illinois Medical District
8.8 out of 10, Excellent, (2,126 reviews)
"Prefect location to walk to everything we wanted & the staff was great!"
United States
Michael
The price is NT$3,110
NT$3,651 total
includes taxes & fees
Apr 1 - Apr 2
Club Quarters Hotel Wacker at Michigan, Chicago

Silversmith Hotel Chicago Downtown

Silversmith Hotel Chicago Downtown
4.0 star property
Theatre District, 4.2 km from Illinois Medical District
9.2 out of 10, Wonderful, (2,232 reviews)
"Bed was comfortable, fresh fruit at breakfast. "
United States
Bradford
Silversmith Hotel Chicago Downtown
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Illinois Medical District

Find the best Illinois Medical District areas and neighborhoods for the activities you enjoy most.

Downtown Chicago

The heart of the Midwest’s glittering metropolis has many offerings, from shopping and dining to parks, museums and exciting contemporary public art.

Magnificent Mile

Upscale shopping district with luxury department stores, boutiques, and acclaimed restaurants, featuring landmarks like the Wrigley Building and Chicago Water Tower. The Magnificent Mile is easily accessible by public transit and seasonal trolley service.

The Loop

Chicago's central business district boasts numerous global businesses, retail establishments, and theaters. Explore the Loop Retail Historic District, Chicago Landmark Historic Michigan Boulevard District, and visit iconic attractions like the Art Institute of Chicago.

River North

Artistic spirit thrives here, with art galleries and a design district featuring luxury interior furnishings. Explore Kingsbury Park, enjoy vibrant nightlife on Hubbard Street, and visit the iconic Contemporaine Building.

Lincoln Park

Upscale national retailers, boutiques, and bookstores abound in this affluent area, alongside numerous restaurants and coffee shops. Must-see attractions include Lincoln Park Zoo, Chicago History Museum, and North Avenue Beach. Easily accessible via CTA transit and major roads.

Top Illinois Medical District Hotel Reviews

Frequently asked questions

What's it like in Illinois Medical District?
Guests are sure to enjoy their time checking out all that Chicago's Illinois Medical District neighborhood has to offer.
Where is the best place to stay in Illinois Medical District?
Based on Expedia customer reviews, Hampton Inn & Suites Chicago Medical District UIC is the highest ranked property in Illinois Medical District. This hotel is a short 15-minute walk from United Center, and it offers free breakfast and an indoor pool. Other top choices in the neighborhood include Hyatt House Chicago Medical/University District and Hyatt Place Chicago Medical/University District.
How many hotels are there in the Illinois Medical District area?
Expedia has 9 Illinois Medical District hotels and other accommodations, and one might make a good home base for venturing out into the greater Chicago area.
If I need to cancel my hotel reservation in Illinois Medical District, will I receive a refund?
Yes! Most hotel reservations are refundable provided that you cancel before the hotel's cancellation deadline, which often is within 24-48 hours of your arrival date. If you booked a non-refundable reservation, you might be able to still cancel and be given a refund within a 24-hour period of booking. Add dates, click "Search", then use the "fully refundable" filter to review the best options available in Illinois Medical District.
Where can I learn more about changing or cancelling my trip to Illinois Medical District?
To access more information about changing or cancelling your trip to Illinois Medical District, head over to our customer service page.
What can I see and do in this Chicago neighborhood?
Don't miss favorite places to visit in the surrounding area, such as Michigan Avenue, United Center, and Soldier Field. Malcolm X College and Michael Jordan Statue are also worth a visit when you're out sightseeing in Chicago.
How can I get around Illinois Medical District and the greater Chicago area?
Ready to get out and explore the city? Polk Station (Pink Line) is the closest metro station.

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