Illinois Medical District Vacations

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Where to stay in Illinois Medical District

Find the best Illinois Medical District areas and neighborhoods for the activities you enjoy most. Learn more about Illinois Medical District
Downtown Chicago showing a city

Downtown Chicago

5 out of top 10 points of interest in this area

The heart of the Midwest’s glittering metropolis has many offerings, from shopping and dining to parks, museums and exciting contemporary public art.

Find hotels in Downtown Chicago

Illinois Medical District Hotel Deals

Hampton Inn & Suites Chicago Medical District UIC

Hampton Inn & Suites Chicago Medical District UIC

2.5 out of 5
710 S Seeley Avenue Chicago IL
Fully refundableReserve now, pay when you stay
The price is NT$2,752 per night from Dec 24 to Dec 25
NT$2,752
NT$3,231 total
Dec 24 - Dec 25
includes taxes & fees
9.6/10 Exceptional! (377 reviews)
Everything was wonderful

Reviewed on 2025/12/19

Hampton Inn & Suites Chicago Medical District UIC
Hilton Chicago/Magnificent Mile Suites

Hilton Chicago/Magnificent Mile Suites

3.5 out of 5
198 E Delaware Pl Chicago IL
Fully refundableReserve now, pay when you stay
The price is NT$2,821 per night from Jan 5 to Jan 6
NT$2,821
NT$3,312 total
Jan 5 - 2026/1/6
includes taxes & fees
8.8/10 Excellent! (3,522 reviews)
Clean room, few dust spots, warm and cozy stay

Reviewed on 2025/12/20

Hilton Chicago/Magnificent Mile Suites
Silversmith Hotel Chicago Downtown

Silversmith Hotel Chicago Downtown

4 out of 5
10 S Wabash Ave Chicago IL
Fully refundableReserve now, pay when you stay
9.2/10 Wonderful! (2,139 reviews)
Clean, comfortable, convenient.

Reviewed on 2025/12/19

Get rates
Silversmith Hotel Chicago Downtown
See all 4,804 properties in Illinois Medical District
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

How much does an Illinois Medical District vacation package cost?
Starting from just , a vacation package is your portal to affordable travel. Custom make your Illinois Medical District trip by picking from our great range of airfares, hotels and rental cars.
How do I get a cheap travel package to Illinois Medical District?
By bundling. Hotels, rental cars and flights — combine whatever you need into an Illinois Medical District vacation package to save loads of cash. Score even more deals when you add extras such as activities or tours to your booking. But that's not the only impressive part. You have the freedom to tailor your vacation your way. We offer more than 550 partner airlines and 1,000,000 hotel options globally, so that everyone has a chance to travel and live out those vacation fantasies.
Where should I stay in Illinois Medical District?
Most travelers who visit Illinois Medical District put both University of Illinois Chicago and United Center on their sightseeing itineraries. Why not choose a hotel that's close to these great attractions?
What are the top hotels in Illinois Medical District?
Reserve a room at Hyatt Place Chicago Medical/University District. It's one of the area's most in-demand hotels. Another great option in Illinois Medical District is Hyatt House Chicago Medical/University District.
How far in advance should I book my Illinois Medical District vacation?
Browse Expedia to compare international flights as soon as possible. In most cases, you can purchase a seat up to 12 months in advance. If you can't find your preferred air carrier, or you've left things to the last moment, don't worry. The lowest prices to Illinois Medical District sometimes occur just weeks before the date of departure.
What does an Expedia Illinois Medical District travel package include?
That depends on what kind of trip you're contemplating. Illinois Medical District vacation deals can include hotels, car rentals and flights. You can mix and match to create the package that suits your budget and style. You can also add on activities and experiences after you've booked to pick up even bigger discounts.
What should I know before booking an Illinois Medical District travel package?
A travel package can be easier on the wallet than separately booking everything you need for your getaway. For example, combine your hotels, flights and rental cars and save a packet. Whatever type of vacation you have in mind, there's bound to be a package that's perfect for you.
Can I choose my airline with an Illinois Medical District Expedia vacation package?
Most definitely. We offer more than 550 airlines around the world, so you can design your Illinois Medical District trip according to your budget and style.
If I'm not able to travel, can I cancel my Illinois Medical District vacation package?
Certainly, and we're here to help. You may be able to change or cancel your Illinois Medical District vacation package for free if you booked in the last 24 hours. But you may be charged a fee by your hotel, airline or car rental company if you booked more than 24 hours ago. If life throws you a curveball, look up our Customer Service Portal for more information.

Discover the most popular places to visit in Illinois Medical District

Magnificent Mile - River North showing night scenes, a city and signage

Michigan Avenue

You can enjoy some retail therapy when you visit Michigan Avenue, a popular shopping spot in Chicago. Amble around this vibrant area's riverfront and enjoy its top-notch restaurants.

Michigan Avenue
Wrigley Field featuring cbd, a sporting event and a city

Wrigley Field

Tour the iconic grounds and catch a game March through September at Chicago’s beloved baseball stadium.

Wrigley Field
Navy Pier featuring a sunset and rides

Navy Pier

A ferris wheel, shopping, restaurants and more can be found in this waterfront entertainment district.

Navy Pier
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.