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Our top choices for Alexander County hotels

Lobby
Quality Inn Cairo I-57

Quality Inn Cairo I-57

Quality Inn Cairo I-57
2.5 star property
Cairo
6.6 out of 10, (273)
"Break fast was excellent "
United States
Uma
The price is NT$2,307
NT$2,560 total
includes taxes & fees
Jan 17 - 2026/1/18
Quality Inn Cairo I-57
Laptop workspace, blackout drapes, free cribs/infant beds, free WiFi
Super 8 by Wyndham Charleston/Sikeston East MO

Super 8 by Wyndham Charleston/Sikeston East MO

Super 8 by Wyndham Charleston/Sikeston East MO
2.0 star property
Charleston
6.6 out of 10, (612)
"Staff was great! Room was nice. "
United States
Lana
The price is NT$1,958
NT$2,173 total
includes taxes & fees
Dec 29 - Dec 30
Super 8 by Wyndham Charleston/Sikeston East MO
Lobby
Quality Inn Charleston - Sikeston

Quality Inn Charleston - Sikeston

Quality Inn Charleston - Sikeston
2.5 star property
Charleston
6.8 out of 10, (406)
"The staff was very friendly and accommodating "
United States
Arturo
The price is NT$2,091
NT$2,320 total
includes taxes & fees
Dec 26 - Dec 27
Quality Inn Charleston - Sikeston
Room, 1 King Bed, Non Smoking | View from room
Eagle Inn Charleston

Eagle Inn Charleston

Eagle Inn Charleston
2.0 star property
Charleston
6.8 out of 10, (103)
"Middle of nowhere hotel was ok"
United States
David
The price is NT$1,908
NT$2,117 total
includes taxes & fees
Dec 30 - Dec 31
Eagle Inn Charleston
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Alexander County Hotel Reviews

Drury Plaza Hotel Cape Girardeau Conference Center

Drury Plaza Hotel Cape Girardeau Conference Center

10/10 Excellent
"Didn’t eat the breakfast but I’m sure it is wonderful. Everything from the Check in process to the condition of the rooms to the comfort of the stay was worth the money "
Corrie 1-night trip
Posted 1 day ago
Drury Plaza Hotel Cape Girardeau Conference Center

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