Alexander County Vacations & Trips

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Top destinations in Alexander County

A steel bridge with a sunset in the background.
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Cairo

Cairo

Alexander County Hotel Deals

Drury Plaza Hotel Cape Girardeau Conference Center

Drury Plaza Hotel Cape Girardeau Conference Center

3 out of 5
3351 Percy Drive Cape Girardeau MO
Fully refundableReserve now, pay when you stay
The price is NT$3,293 per night from Nov 8 to Nov 9
NT$3,293
NT$3,715 total
Nov 8 - Nov 9
includes taxes & fees
Drury Plaza Hotel Cape Girardeau Conference Center
Pear Tree Inn Cape Girardeau West

Pear Tree Inn Cape Girardeau West

2.5 out of 5
103 Cape West Pkwy Cape Girardeau MO
Fully refundableReserve now, pay when you stay
The price is NT$2,371 per night from Nov 15 to Nov 16
NT$2,371
NT$2,675 total
Nov 15 - Nov 16
includes taxes & fees
9.2/10 Wonderful! (1,000 reviews)
"Will stay again"

Reviewed on 2026/11/2

Pear Tree Inn Cape Girardeau West
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

3 out of 5
3003 SOUTH OLD ORCHARD ROAD Jackson MO
Fully refundableReserve now, pay when you stay
The price is NT$2,632 per night from Nov 9 to Nov 10
NT$2,632
NT$2,848 total
Nov 9 - Nov 10
includes taxes & fees
8.8/10 Excellent! (893 reviews)
"I reserved this room for one of my Service Members, he reported that the front desk staff was rude when he went to them to ask to be moved due to how loud the people next to him were being. It got to the point that people were knocking on his door repeatedly. He felt so unsafe he slept in his car ..."

Reviewed on 2026/11/6

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
See all 227 properties in Alexander County
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

How much does an Alexander County vacation package cost?
Maybe less than you might think — from as low as , actually! By combining hotels, flights and car rentals into your own tailor-made vacation package, your getaway to Alexander County is only clicks away.
How do I get a cheap travel package to Alexander County?
Our Alexander County vacation packages promise plenty of savings for the savvy wanderer. For the best deal, simply combine your flights, hotels and rental cars into a convenient package. But great bargains are just the beginning of your next unforgettable adventure. When you book with Expedia, you'll have more than 550 airlines and 1,000,000 hotel options globally to select from. Whatever your style or budget, there's a vacation package here just for you.
What are the top hotels in Alexander County?
If you're headed to Tamms, you can't go wrong with Quality Inn Cairo I-57 and Beautiful Cabin Retreat. Both are great bases for discovering this unique Alexander County city.
How far in advance should I book my Alexander County vacation?
Reserving your flights early with Expedia means one less thing to worry about. Many air carriers advertise prices up to 12 months prior to departure dates. Typically, this is the cheapest time to book. If circumstances have left you booking late, incredible deals to Alexander County sometimes emerge just a few weeks before departure.
What does an Expedia Alexander County travel package include?
Flights, hotels and a cool car for all your road trip adventures. Simply choose your favorite bundle and gain access to great discounts. Once you've made your booking, add on some tours and experiences and watch your savings grow. When it comes to creating your Alexander County getaway, you're in control!
Can I choose my airline with an Alexander County Expedia vacation package?
Yes — and it's simple too. Expedia has access to more than 550 partner airlines worldwide. Our vacation packages give you the flexibility to take your pick of available flights, hotels and activities that suit you.
If I'm not able to travel, can I cancel my Alexander County vacation package?
You can. We totally understand that life happens, so we're happy to help if you have to make changes to your Alexander County vacation package. You may be able to cancel or change your itinerary for free if you've booked within 24 hours. Your hotel, airline or car rental company may impose a fee if you booked more than 24 hours ago. Take a look at our Customer Service Portal for further information. Also, check your itinerary for the nitty-gritty on change fees.

Stay near popular Alexander County attractions

Fort Defiance State Park

7.4/10 (15 reviews)
You can take time to visit Fort Defiance State Park during your travels to Cairo. Stroll along the riverfront or visit the churches while you're in the area.
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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.