Find Resorts & Hotels with Spas in West End, SC

Start date: Check-in selected.
To Date
End date: Check-out

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check availability on West End Resorts & Hotels with Spas

Tonight
Dec 4 - Dec 5
Tomorrow
Dec 5 - Dec 6
This weekend
Dec 5 - Dec 7
Next weekend
Dec 12 - Dec 14

Top West End Resorts & Hotels with Spas

Couples treatment rooms, body treatments, body wraps, body scrubs
Hotel Hartness

Hotel Hartness

4.0 star property
Greenville
9.8 out of 10, Exceptional, (624)
"Beautiful location, friendly staff"
United States
Andrew
The price is NT$5,033
NT$6,597 total
includes taxes & fees
Dec 7 - Dec 8
Hotel Hartness
Spa
Grand Bohemian Lodge Greenville, Autograph Collection

Grand Bohemian Lodge Greenville, Autograph Collection

4.0 star property
Greenville Downtown
9.6 out of 10, Exceptional, (411)
"The staff were really sweet and responsive. The views from the rooms are breathtaking! "
United States
Krystal
The price is NT$7,598
NT$8,586 total
includes taxes & fees
Jan 4 - 2026/1/5
Grand Bohemian Lodge Greenville, Autograph Collection
Bar (on property)
Hotel Domestique

Hotel Domestique

4.0 star property
Travelers Rest
9.6 out of 10, Exceptional, (30)
"Overall it was an exceptional experience and would highly recommend to anyone looking for a quiet get away."
United States
Chuck
The price is NT$10,178
NT$11,196 total
includes taxes & fees
Jan 1 - 2026/1/2
Hotel Domestique
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Top West End Hotel Reviews

La Quinta Inn & Suites by Wyndham Greenville Haywood

La Quinta Inn & Suites by Wyndham Greenville Haywood

10/10 Excellent
"The staff is so friendly and they are very accommodating. Eddie from the front desk is always kind. Good breakfast "
Dorothea 1-night trip
Posted 4 days ago
La Quinta Inn & Suites by Wyndham Greenville Haywood

Explore a world of travel with Expedia

Frequently asked questions

Looking to vacation at a spa hotel in West End?
Forget the stress of everyday life and book yourself a hotel with a spa. Immerse yourself in nature at the waterfalls and riverfront in West End. Spa hotels are a great way to break out of your routine and add a layer of luxury to your holiday.
What's there to see and do in West End?
Experience West End with a stop at Fluor Field at the West End, The Peace Center, and The Children's Museum of the Upstate. If you have spare time during your trip, you might want to make a stop at Bon Secours Wellness Arena and Greenville Zoo.
What is a West End spa hotel?
Spa hotels in West End have on-site spas and offer services like therapies and a choice of body treatments. Some also provide a selection of in-room treatments for the ultimate luxury. Spa hotels are ideal if you are looking for some R&R during your vacation.