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Our top choices for Santo Spirito hotels

Mamo Florence - Bice & Krizia Apartments

Mamo Florence - Bice & Krizia Apartments
Santo Spirito
9.4 out of 10, Exceptional, (3 reviews)
"Very nice apartment and great location. The included parking and laundry facilities were the reason we selected the property, and were very happy with everything. Overall a lovely stay. "
United States
Michele
The price is NT$4,957
NT$9,207 total
includes taxes & fees
Apr 22 - Apr 23
Mamo Florence - Bice & Krizia Apartments

Foresteria Valdese di Firenze - Casa per Ferie

Foresteria Valdese di Firenze - Casa per Ferie
Santo Spirito
8.8 out of 10, Excellent, (198 reviews)
"The room was clean a d comfortable, and the staff was very courteous and helpful. The location was also good with most attractions being a 30 to 40 minute walk or less."
United States
Roger
The price is NT$3,524
NT$4,318 total
includes taxes & fees
Apr 8 - Apr 9
Foresteria Valdese di Firenze - Casa per Ferie

1900 Artevita

1900 Artevita
Santo Spirito
8.8 out of 10, Excellent, (179 reviews)
"Our stay here was wonderful! The host was so pleasant and the view from the terrace was beautiful. The location was in a great spot for enjoying the Florentine neighborhoods, and close to many of the restaurants recommended to us. We would stay here again in a heartbeat."
United States
Bianca
The price is NT$4,467
NT$5,356 total
includes taxes & fees
Apr 14 - Apr 15
1900 Artevita

La Fonderia Firenze

La Fonderia Firenze
Santo Spirito
9.6 out of 10, Exceptional, (175 reviews)
"The room was beautiful and clean, the staff was pleasant, breakfast was fantastic, 10/10"
United States
Dan
The price is NT$5,628
NT$6,632 total
includes taxes & fees
Apr 27 - Apr 28
La Fonderia Firenze

La Torre Del Cestello

La Torre Del Cestello
Santo Spirito
9.2 out of 10, Wonderful, (246 reviews)
"It was in a great location, we had an excellent view from our room."
United States
Tonya
The price is NT$5,364
NT$6,416 total
includes taxes & fees
Apr 9 - Apr 10
La Torre Del Cestello

L'Antica Porta Boutique B&B

L'Antica Porta Boutique B&B
Santo Spirito
9.0 out of 10, Wonderful, (22 reviews)
"Very goord place to stay"
United States
Victor
The price is NT$4,581
NT$5,480 total
includes taxes & fees
Apr 12 - Apr 13
L'Antica Porta Boutique B&B

Appartamenti degli Artisti by Mmega

Appartamenti degli Artisti by Mmega
Santo Spirito
8.6 out of 10, Excellent, (32 reviews)
"Nice location with easy access to bus stops. Close to good restaurants and bars. "
United States
Prasanna
The price is NT$3,119
NT$6,817 total
includes taxes & fees
Apr 10 - Apr 11
Appartamenti degli Artisti by Mmega

Residenza D'Epoca Al Numero 8

Residenza D'Epoca Al Numero 8
Santo Spirito
9.0 out of 10, Wonderful, (147 reviews)
"Excellent location and very friendly staff."
Canada
Scott
The price is NT$4,981
NT$5,994 total
includes taxes & fees
Apr 9 - Apr 10
Residenza D'Epoca Al Numero 8

Drom Florence Rooms & Apartments

Drom Florence Rooms & Apartments
Santo Spirito
9.8 out of 10, Exceptional, (140 reviews)
"Claudia was a great hostess who greeted us at the door and explained the room and comings and goings. She was gracious to hold our luggage on our last day before departing by train. "
United States
Anita
The price is NT$4,737
NT$5,652 total
includes taxes & fees
Apr 7 - Apr 8
Drom Florence Rooms & Apartments

Ottantotto Firenze

Ottantotto Firenze
Santo Spirito
9.6 out of 10, Exceptional, (170 reviews)
"Great location and extremely charming!"
United States
Brook
The price is NT$7,178
NT$8,411 total
includes taxes & fees
Apr 12 - Apr 13
Ottantotto Firenze

Mamo Florence - Turandot Apartment

Mamo Florence - Turandot Apartment
Santo Spirito
10.0 out of 10, Exceptional, (1 review)
"L'appartement est très bien situé, confortable et calme. Seul bémol, le wifi pas performant."
France
Bertrand
The price is NT$5,728
NT$10,424 total
includes taxes & fees
Apr 26 - Apr 27
Mamo Florence - Turandot Apartment

Palazzo D'Oltrarno - Residenza D'Epoca

Palazzo D'Oltrarno - Residenza D'Epoca
Santo Spirito
9.6 out of 10, Exceptional, (48 reviews)
"Excellent place to stay!"
United States
Diane
The price is NT$8,275
NT$9,544 total
includes taxes & fees
May 5 - May 6
Palazzo D'Oltrarno - Residenza D'Epoca

Hotel Firenze 2000

Hotel Firenze 2000
2.0 star property
Santo Spirito
7.2 out of 10, Good, (194 reviews)
"The staff was wonderful and very helpful; 24 hr service ! The room was very clean and breakfast was plentiful. Great location if you don’t mind a short walk to the historic town center ; would definitely recommend."
Canada
Josee
The price is NT$3,310
NT$3,973 total
includes taxes & fees
Apr 12 - Apr 13
Hotel Firenze 2000

Palazzo Oliveto

Palazzo Oliveto
Santo Spirito
7.4 out of 10, Good, (93 reviews)
"Great service easy check in Clean safe quiet "
United States
Gabriel
The price is NT$2,957
NT$3,694 total
includes taxes & fees
Apr 27 - Apr 28
Palazzo Oliveto

Oltrarno Splendid

Oltrarno Splendid
Santo Spirito
10.0 out of 10, Exceptional, (114 reviews)
"Fabulous place to stay"
United Kingdom
Kenneth
The price is NT$11,113
NT$12,739 total
includes taxes & fees
Apr 6 - Apr 7
Oltrarno Splendid

AdAstra Suites

AdAstra Suites
Santo Spirito
9.8 out of 10, Exceptional, (226 reviews)
"Gorgeous room in a beautiful property, very helpful staff, tranquil setting"
United Kingdom
Olivia
The price is NT$11,344
NT$12,993 total
includes taxes & fees
Apr 6 - Apr 7
AdAstra Suites

Torre di Bellosguardo

Torre di Bellosguardo
4.0 star property
Santo Spirito
9.0 out of 10, Wonderful, (103 reviews)
"Beautiful property and wonderful staff."
United States
Brad
The price is NT$17,962
NT$20,274 total
includes taxes & fees
Apr 12 - Apr 13
Torre di Bellosguardo

Mamo Florence - Boheme Apartment

Mamo Florence - Boheme Apartment
Santo Spirito
Mamo Florence - Boheme Apartment

SPIRIT OF FLORENCE Boutique Rooms

SPIRIT OF FLORENCE Boutique Rooms
Santo Spirito
10.0 out of 10, Exceptional, (25 reviews)
"Great place to stay for our visit to Florence. Walking distance to everything but in quiet neighborhood. Staff are very friendly and helpful. "
United States
Wendy
The price is NT$9,607
NT$11,009 total
includes taxes & fees
Apr 13 - Apr 14
SPIRIT OF FLORENCE Boutique Rooms

Sauro River View by MMega

Sauro River View by MMega
Santo Spirito
10.0 out of 10, Exceptional, (2 reviews)
"Very nice place to stay!"
United States
Luis Miguel
The price is NT$3,509
NT$7,246 total
includes taxes & fees
Apr 9 - Apr 10
Sauro River View by MMega
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Santo Spirito

Find the best Santo Spirito areas and neighborhoods for the activities you enjoy most. Learn more about Santo Spirito
Learn more about Santo Spirito

Historic Centre of Florence

Lose yourself in the Renaissance charm of Florence’s old town, where masterpieces by Brunelleschi and Giotto line up alongside cafés, gelato shops and trattorias.

Duomo

Cathedral of Santa Maria del Fiore and Piazza di Santa Maria Novella are just a few worthwhile attractions to visit in Duomo. Travelers also love the fascinating museums, stunning cathedral, and popular shops.

San Giovanni

If you're spending some time in San Giovanni, Cathedral of Santa Maria del Fiore and Piazza della Repubblica are top sights worth seeing.

Santa Maria Novella

Enjoy the popular shops in Santa Maria Novella. Piazza di Santa Maria Novella is a worthwhile stop, and you can jump on the metro at Porta al Prato - Leopolda Tram Stop or Fratelli Rosselli Tram Stop to see more of Porta al Prato.

Santa Croce

Travelers come to Santa Croce for its interesting museums, and you can see top attractions like Basilica of Santa Croce and Piazza Santa Croce while you're in town.

Top Santo Spirito Hotel Reviews

Frequently asked questions

What is Santo Spirito like?
Santo Spirito is a trendy neighborhood known for its beautiful river views. Be sure to check out Piazza Santo Spirito and Santo Spirito Basilica as part of your Santo Spirito travel plans.
What's the best accommodation in Santo Spirito?
Based on Expedia customer reviews, AdAstra Suites is the highest ranked property in Santo Spirito. This B&B is a short 11-minute walk from Ponte Vecchio, and it offers free breakfast and free WiFi. Other favorite options in the area include Hotel Horto Convento and La Fonderia Firenze.
How many hotels can I expect to find in the Santo Spirito area?
Expedia has 495 hotels and other accommodations in Santo Spirito to choose from, making this an ideal home base for exploring the greater Florence area.
If I need to cancel my hotel reservation in Santo Spirito, will I receive a refund?
Yes, the majority of hotel reservations are refundable provided that you cancel prior to the hotel's cancellation deadline, which often is within 24-48 hours of your check-in date. If you booked a non-refundable reservation, it might still be possible to cancel it and be given a refund within a 24-hour period of booking. Enter dates in and click on "Search", then you can filter by "fully refundable" to get the best deals in Santo Spirito.
Where can I learn more about changing or cancelling my trip to Santo Spirito?
To find more details about updating your trip to Santo Spirito or cancelling it, head over to our customer service page.
What can I see and do in this Florence neighborhood?
Spend some time exploring the natural setting of Santo Spirito with a visit to Arno River and Torrigiani Garden. As you're discovering the neighborhood, Piazza Santo Spirito and Santo Spirito Basilica are some other places worth a visit. Piazza di Santa Maria Novella and Cathedral of Santa Maria del Fiore are some favorite places to visit in the area around Santo Spirito. When you're sightseeing in Florence, Piazza del Carmine and Santa Maria della Carmine are also worth a stop.