What is Santo Spirito like?

Santo Spirito is a trendy neighborhood known for its beautiful river views. Be sure to check out Piazza Santo Spirito and Santo Spirito Basilica as part of your Santo Spirito travel plans.

What's the best accommodation in Santo Spirito?

Based on our traveler data, Hotel Horto Convento is one of the top choices for your stay in Santo Spirito. This hotel is a short 14-minute walk from Piazza di Santa Maria Novella, and it offers free breakfast and a bar. Other good options for your stay in the neighborhood include La Torre Del Cestello and UNA Hotels Vittoria Firenze .

How many hotels can I expect to find in the Santo Spirito area?

Expedia has 538 hotels and other accommodations in Santo Spirito to choose from, making this an ideal home base for exploring the greater Florence area.

If I need to cancel my hotel reservation in Santo Spirito, will I receive a refund?

Yes, the majority of hotel reservations are refundable provided that you cancel prior to the hotel's cancellation deadline, which often is within 24-48 hours of your check-in date. If you booked a non-refundable reservation, it might still be possible to cancel it and be given a refund within a 24-hour period of booking. Enter dates in and click on "Search", then you can filter by "fully refundable" to get the best deals in Santo Spirito.

Where can I learn more about changing or cancelling my trip to Santo Spirito?

To find more details about updating your trip to Santo Spirito or cancelling it, head over to our customer service page .

What can I see and do in this Florence neighborhood?

Spend some time exploring the natural setting of Santo Spirito with a visit to Arno River and Torrigiani Garden. As you're discovering the neighborhood, Piazza Santo Spirito and Santo Spirito Basilica are some other places worth a visit. Piazza di Santa Maria Novella and Piazza del Duomo are some favorite places to visit in the area around Santo Spirito. When you're sightseeing in Florence, Piazza del Carmine and Santa Maria della Carmine are also worth a stop.

Top Santo Spirito Hotels

A grand church interior with high vaulted ceilings, large columns, and a central altar.

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Our top choices for Santo Spirito hotels

A spacious living room with a large grey sofa, yellow armchairs, and a chandelier.

1. Hotel Horto Convento

Santo Spirito

NT$5,657 total

includes taxes & fees

Nov 3 - Nov 4

A spacious bedroom with a large bed, a clawfoot bathtub, a television, and a chandelier.

2. Oltrarno Splendid

Santo Spirito

Kimberly

NT$7,911 total

includes taxes & fees

Nov 5 - Nov 6

A spacious living room with a fireplace, a chandelier, and a bar area.

3. AdAstra Suites

Santo Spirito

Laurel

NT$8,734 total

includes taxes & fees

Nov 8 - Nov 9

4. La Torre Del Cestello

Santo Spirito

Martin

NT$3,955 total

includes taxes & fees

Nov 4 - Nov 5

A restaurant with multiple tables and chairs, a bar area, and large windows allowing natural light.

5. UNA Hotels Vittoria Firenze

Santo Spirito

Pablo

NT$3,803 total

includes taxes & fees

Nov 1 - Nov 2

A cozy reading nook with a fireplace, bookshelves, and comfortable seating.

6. Ottantotto Firenze

Santo Spirito

Roslyn

NT$8,213 total

includes taxes & fees

Nov 15 - Nov 16

A modern bedroom with a large bed, a desk with chairs, and a bathroom visible through an open door.

7. Palazzo Mannaioni Suites

Santo Spirito

Diana

NT$4,677 total

includes taxes & fees

Nov 2 - Nov 3

A hotel room with a bed, a table, and chairs outside the window.

8. La Fonderia Firenze

Santo Spirito

lewisa

NT$5,451 total

includes taxes & fees

Oct 22 - Oct 23

A grand hallway with a high ceiling, large wooden doors, and classical columns.

9. Casa Santo Nome di Gesù

Santo Spirito

Laila

NT$4,894 total

includes taxes & fees

Nov 1 - Nov 2

Two wine glasses on a balcony with a view of a tower and buildings in the background.

10. Hotel Palazzo Guadagni

Santo Spirito

Suzanne

NT$8,682 total

includes taxes & fees

Nov 15 - Nov 16

A view through an open window of a cityscape with historic architecture, including domed buildings and a prominent tower.

11. Torre di Bellosguardo

Santo Spirito

Brad

NT$19,797 total

includes taxes & fees

Oct 16 - Oct 17

A narrow cobblestone street with a parked white scooter and a table with chairs in the background.

12. Drom Florence Rooms & Apartments

Santo Spirito

Yegor

NT$3,812 total

includes taxes & fees

Nov 9 - Nov 10

13. Residenza D'Epoca Al Numero 8

Santo Spirito

Kristen B.

NT$3,835 total

includes taxes & fees

Nov 9 - Nov 10

A gravel pathway leading to a building with a balcony, surrounded by lush greenery and various plants.

14. Palazzo D'Oltrarno - Residenza D'Epoca

Santo Spirito

Diane

NT$3,994 total

includes taxes & fees

Nov 11 - Nov 12

A covered courtyard with columns, a bench, and potted plants.

15. Foresteria Valdese di Firenze - Casa per Ferie

Santo Spirito

Anna

NT$3,408 total

includes taxes & fees

Nov 1 - Nov 2

A hotel room with a bed, a table with a plate of food, a bottle of wine, and a chair. There is a window with curtains, a radiator, and a wall-mounted TV.

16. 1900 Artevita

Santo Spirito

Selena

NT$3,370 total

includes taxes & fees

Nov 5 - Nov 6

A bedroom with a bed, a chair, a desk with a mirror, and artwork on the walls.

17. SPIRIT OF FLORENCE Boutique Rooms

Santo Spirito

Nicole

NT$5,413 total

includes taxes & fees

Nov 5 - Nov 6

A hotel named "Youth Firenze 2000" with a sign indicating a bar inside.

18. Hotel Firenze 2000

Santo Spirito

Hans

NT$3,909 total

includes taxes & fees

Nov 15 - Nov 16

A hotel room with a bed, two chairs, a window with a view, and a vase with flowers.

19. Palazzo Oliveto

Santo Spirito

Mary Mariam

NT$2,297 total

includes taxes & fees

Nov 15 - Nov 16

A stone building with a wooden door and a bicycle parked outside.

20. Santo Spirito Venti

Santo Spirito

Konner

NT$4,766 total

includes taxes & fees

Nov 12 - Nov 13

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Where to stay in Santo Spirito

Find the best Santo Spirito areas and neighborhoods for the activities you enjoy most. Learn more about Santo Spirito

A river with buildings on the right bank.

Historic Centre of Florence

Lose yourself in the Renaissance charm of Florence’s old town, where masterpieces by Brunelleschi and Giotto line up alongside cafés, gelato shops and trattorias.

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A historic church with intricate architecture and a large open plaza with people.

Santa Maria Novella

Enjoy the popular shops in Santa Maria Novella. Piazza di Santa Maria Novella is a worthwhile stop, and you can jump on the metro at Porta al Prato - Leopolda Tram Stop or Fratelli Rosselli Tram Stop to see more of Florence.

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A historic building with intricate architectural details, including a dome and ornate facades.

Duomo

Piazza del Duomo and Piazza di Santa Maria Novella are just a few worthwhile attractions to visit in Duomo. Travelers also love the fascinating museums, stunning cathedral, and popular shops.

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A historic bridge with arches over a river, surrounded by yellow buildings and a crowd of people.

San Giovanni

If you're spending some time in San Giovanni, Piazza della Repubblica and Via de' Calzaiuoli are top sights worth seeing.

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A grand cathedral with intricate architectural details, including statues and ornate decorations.

Santa Croce

Travelers come to Santa Croce for its interesting museums, and you can see top attractions like Basilica of Santa Croce and Piazza Santa Croce while you're in town.

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Top Santo Spirito Hotel Reviews

Palazzo Mannaioni Suites

10/10 Excellent

"Nice location close to San Spirito Square. The kitchenette was well stocked. Quiet street across the river."

Drom Florence Rooms & Apartments

10/10 Excellent

"Lovely accommodations, full of history and charm. You go through the gate into the courtyard and you're in another world. Wonderful continental breakfast in the morning sitting at the little table and chairs in the courtyard. Whole experience was really a treat. Claudia was really great at communicating everything we needed on the WhatsApp before we arrived and the bed was very comfortable. Very close to everything you want to see in Florence. We started with Boboli Gardens and that was amazing!We highly recommend Drom Florence!"

Foresteria Valdese di Firenze - Casa per Ferie

10/10 Excellent

"It is in a great location! Close to the River Arno and major attractions. It is basic accommodation though. The staff were efficient at check in and we didn’t see them again. The rooms have fridges in the closest. The bathrooms were new & modern and comfortable beds. Very clean and air con was lovely!"

Casa Santo Nome di Gesù

10/10 Excellent

"The photos were good but the reality is even better. This was a nunnery previously and is a traditional building set on a piazza. Imagine cool tiles, sweeping staircases and huge wooden doors. Spotlessly clean with large airy rooms and shuttered windows overlooking (in our case) rooftops and onto the hills beyond. A short walk to all the major sites, good breakfast and peaceful garden...perfect!"

Palazzo D'Oltrarno - Residenza D'Epoca

8/10 Good

"Great location on the less touristy side of the Arno River near local restaurants and bars. Giulia at the front desk was wonderful as well!! Cons: The air conditioner was not strong enough for the heat wave leaving the room at 26.5C/80F each night. The shower design was modern but didn’t drain well, so flooded the floor during each shower. No one was at the desk at 8am to check me out , pay local taxes, and order a taxi, so that was a little stressful. Pros: very secure & quiet building, legit platform King bed (not 2 beds pushed together) with a firm mattress was heaven for us. The room was huge with old frescoes on the ceiling that was super cool!"

Find hotels in Santo Spirito, Florence

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Our top choices for Santo Spirito hotels

1. Hotel Horto Convento

2. Oltrarno Splendid

3. AdAstra Suites

4. La Torre Del Cestello

5. UNA Hotels Vittoria Firenze

6. Ottantotto Firenze

7. Palazzo Mannaioni Suites

8. La Fonderia Firenze

9. Casa Santo Nome di Gesù

10. Hotel Palazzo Guadagni

11. Torre di Bellosguardo

12. Drom Florence Rooms & Apartments

13. Residenza D'Epoca Al Numero 8

14. Palazzo D'Oltrarno - Residenza D'Epoca

15. Foresteria Valdese di Firenze - Casa per Ferie

16. 1900 Artevita

17. SPIRIT OF FLORENCE Boutique Rooms

18. Hotel Firenze 2000

19. Palazzo Oliveto

20. Santo Spirito Venti

Where to stay in Santo Spirito

Historic Centre of Florence

Santa Maria Novella

Duomo

San Giovanni

Santa Croce

Top Santo Spirito Hotel Reviews

Palazzo Mannaioni Suites

Frequently asked questions

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