The Best Hotels Closest to Santo Domingo Square in Cartagena for 2026

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Our top choices for Santo Domingo Square hotels

An indoor corridor with arches, a central column, and a dining area with tables and chairs.

An indoor swimming pool with tiled walls and a wooden floor, surrounded by lush green plants and a white building with wooden window frames.

A courtyard with a wooden pergola, palm trees, and potted plants.

A building with a balcony, arched windows, and a door with a wreath.

1. Hotel Quadrifolio

Cartagena Centro, 0.2 km from Santo Domingo Square

ELIZER

NT$10,792

NT$10,792 total

Oct 26 - Oct 27

A spacious indoor area with wicker furniture, a pool, and a brick archway.

A rooftop terrace with a white sofa, wicker chairs, and a pool.

A spacious indoor area with wicker furniture, a pool, and potted plants.

A dining area with striped chairs and a wooden table set for a meal.

2. Casa La Merced by Mustique

San Diego, 0.3 km from Santo Domingo Square

Harry

NT$9,054

NT$9,054 total

Sep 28 - Sep 29

A courtyard with potted plants, a stone fountain, and a wooden balcony.

A staircase leading to an upper level, with a balcony above. There are potted plants and a table with chairs outside.

A courtyard with potted plants, a stone fountain, and a tree.

A room with a bed, two rocking chairs, a small table with books, a lamp, and a ceiling fan.

3. Casa Baloco

Cartagena Centro, 0.1 km from Santo Domingo Square

Juan

NT$19,407

NT$19,407 total

Oct 26 - Oct 27

A hallway with a stone floor, wooden beams, and a large potted plant.

A hallway with a stone floor, a large potted plant, wall-mounted light fixtures, and a decorative wall piece.

A balcony with a railing, a potted plant, and a building with a tiled roof in the background.

A courtyard with a tiled floor, a small pool, and a balcony with wooden railings.

4. Privado Designer Boutique Hotel

San Diego, 0.5 km from Santo Domingo Square

Katherine

NT$4,246

NT$4,246 total

Oct 6 - Oct 7

5. Casa Belle Cartagena Hotel Boutique

San Diego, 0.5 km from Santo Domingo Square

Yennie

NT$6,027

NT$6,027 total

Oct 22 - Oct 23

A modern outdoor pool area with a lounge chair and a small table, surrounded by a geometric patterned fence.

A multi-level atrium with wooden railings, stone columns, and lush greenery.

A lobby with a reception desk, a red sofa, and a staircase leading to an outdoor area with plants.

A modern hotel room with a large bed, a wooden headboard, a wall-mounted air conditioner, a small desk with a chair, and a decorative plant.

6. Hotel Boutique Casona del Porvenir

Cartagena Centro, 0.3 km from Santo Domingo Square

Jacqueline

NT$6,724

NT$6,724 total

Oct 18 - Oct 19

A pool area with stone columns, water features, and outdoor seating.

A courtyard with a pool, wooden furniture, and a dining area.

A breakfast buffet with various food items and condiments.

A hotel room with a large bed, a wooden ceiling, a sliding glass door to a bathroom, and a wall-mounted lamp.

7. Palacio del Agua by Faranda Boutique

Cartagena Centro, 0.3 km from Santo Domingo Square

Marycela

NT$8,544

NT$8,544 total

Oct 1 - Oct 2

A hotel entrance with a wooden door, a sign reading "Casa la Cartuja," and a white column with a grid-like pattern.

A hotel room with a large bed, two bedside tables with lamps, a wall-mounted fan, and a window with curtains.

A hotel room with a bed, two bedside lamps, a ceiling fan, and a view of a balcony with plants.

A hallway with a staircase, a wall-mounted planter with various plants, and a tiled wall with a blue mosaic pattern.

8. Casa La Cartujita

San Diego, 0.5 km from Santo Domingo Square

Ruben

NT$5,756

NT$5,756 total

Sep 27 - Sep 28

A pool area with lounge chairs and a stone wall.

A rooftop terrace with wicker furniture, a table set for dining, and a bell tower in the background.

A dining area with a chandelier, wooden ceiling, and tables set for dining.

A bar area with wooden chairs, a counter with bottles, and hanging crystal chandeliers.

9. Hotel Casa San Agustin

Cartagena Centro, 0.3 km from Santo Domingo Square

David

NT$18,354

NT$18,354 total

Oct 15 - Oct 16

A swimming pool with a view of historic buildings, including a church with a dome and bell tower.

A modern bedroom with a large bed, a sofa, and a balcony with plants.

A balcony with pink flowers, a person holding a drink, and buildings in the background.

A modern living room with a white coffee table, two sofas, a dining area with a table and chairs, and a large window with blinds.

10. Casa Claver Loft Boutique Hotel

Cartagena Centro, 0.2 km from Santo Domingo Square

Kevin

NT$6,108

NT$6,108 total

Sep 30 - Oct 1

A high-ceilinged wooden room with a large bathtub, two small tables, and a bench.

A spacious lobby with a central seating area, a large hanging light fixture, and a polished floor.

A spacious indoor courtyard with a wooden floor, a central seating area with tables and chairs, and a large potted plant.

A restaurant with a wooden reception desk, bar area, and seating.

11. Hotel Casona del Colegio

Cartagena Centro, 0.3 km from Santo Domingo Square

Jamie

NT$7,134

NT$7,134 total

Oct 7 - Oct 8

A swimming pool with a tiled deck, surrounded by lush greenery and a building with a balcony.

A spacious indoor courtyard with a central palm tree, surrounded by various plants and a stone staircase leading to an upper level.

A spacious lobby with a high ceiling, a central staircase, and a decorative wooden fence.

A multi-story building with a classic architectural style, featuring a central entrance with a dark door, multiple windows on each floor, and decorative ironwork.

12. Cinco Quintas Hotel Boutique

Cartagena Centro, 0.3 km from Santo Domingo Square

Fernando

NT$7,404

NT$7,404 total

Oct 8 - Oct 9

A cozy living room with a white sofa, a wicker bench, a coffee table with a bowl of nuts, and a large mirror reflecting the room.

A pool area with a view of a church tower, surrounded by palm trees and outdoor seating.

A rustic indoor garden with a water feature, brick pathway, and lush greenery.

A restaurant with a long wooden table, wicker chairs, hanging lights, and a stone wall.

13. Amarla Boutique Hotel Cartagena

Cartagena Centro, 0.1 km from Santo Domingo Square

Matt

NT$8,996

NT$8,996 total

Sep 27 - Sep 28

A wicker swing chair with ropes, a stone pillar, and a seating area with cushions.

A barista preparing a drink at a counter with a view of an outdoor pool and a staircase.

A bedroom with a bed, a TV, a sofa, and a dining area.

14. Casa Carolina Luxury Wellness Hotel

Cartagena Centro, 0.2 km from Santo Domingo Square

Kevin

NT$10,270

NT$10,270 total

Sep 28 - Sep 29

A swimming pool with clear water, surrounded by lush greenery and flowering plants.

A spacious indoor area with a dining table and chairs, a sofa, and a lamp.

A building with a white facade, wooden window bars, and a sign that reads "Bastion."

A spacious atrium with a central seating area, large windows, and a reflective floor.

15. Bastión Luxury Hotel

San Diego, 0.4 km from Santo Domingo Square

Santiago

NT$11,514

NT$11,514 total

Oct 25 - Oct 26

A rooftop pool area with lounge seating, a pool, and a view of a historic building.

An outdoor seating area with a sofa, chairs, and a large umbrella.

A hotel room with a bed, a television, a wooden wardrobe, and a wicker chair.

A restaurant with checkered flooring, tables set with wine glasses, and a wall-mounted menu board.

16. Sophia Hotel By OxoHotel

Cartagena Centro, 0.3 km from Santo Domingo Square

Anthony

NT$9,540

NT$9,540 total

Sep 28 - Sep 29

A person in a swimming pool with a table in the foreground holding drinks and a pineapple.

A modern living room with a sofa, coffee table, and a painting on the wall.

A room with a large window, a leather sofa, a wooden chair, and a glass table.

A bartender pouring drinks into glasses at a bar.

17. Townhouse Boutique Hotel

Cartagena Walled City, 0.4 km from Santo Domingo Square

Samer

NT$4,150

NT$4,150 total

Oct 25 - Oct 26

A patio with wicker furniture, a stone wall, and a glass door.

A hotel room with a wooden cabinet, two lamps, a sofa, and a large window with curtains.

A spacious living area with a dining table, chairs, a sofa, and a patterned rug.

An outdoor swimming pool with lounge chairs and umbrellas, surrounded by a patio area with tables and chairs.

18. Hotel Casa del Gobernador

Cartagena Centro, 0.2 km from Santo Domingo Square

Peyton

NT$7,638

NT$7,638 total

Oct 1 - Oct 2

A grand lobby with a central seating area, a staircase, and a large plant.

A grand hallway with high ceilings, ornate columns, and a large chandelier.

A man and a woman relaxing on a striped floating platform in a clear pool.

19. Four Seasons Hotel & Residences Cartagena

Getsemani, 0.6 km from Santo Domingo Square

john

NT$20,641

NT$20,641 total

Sep 28 - Sep 29

A pool area with a spiral staircase, lounge chairs, and potted plants.

An ornate wooden door with brass handles, a chandelier, and a table with potted plants.

A spacious living room with two sofas, a wooden coffee table, and a ceiling fan.

An outdoor patio area with wooden furniture, umbrellas, and a pool.

20. Casa Pestagua Relais Châteaux

Cartagena Centro, < 0.1 km from Santo Domingo Square

Emil

NT$20,984

NT$20,984 total

Oct 1 - Oct 2

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Compare popular hotels close to Santo Domingo Square

Property	Property class	Guest rating
Hotel Quadrifolio	10.0 Exceptional 167 reviews	View
Casa La Merced by Mustique	10.0 Exceptional 37 reviews	View
Casa Baloco	10.0 Exceptional 10 reviews	View
Privado Designer Boutique Hotel	9.8 Exceptional 183 reviews	View
Casa Belle Cartagena Hotel Boutique	10.0 Exceptional 11 reviews	View

Top Santo Domingo Square Hotel Reviews

Osh Hotel Cartagena

8/10 Good

"Lo único que no me gustó fue que a la hora del check out me cobraron un impuesto de $150,000 pesos colombianos que nadie me mencionó durante el proceso de reservación o a la hora del check in. Y también trataron de cobrarme por algunas otras cosas que no pedí. Como comida. Finalmente solo pagué por el impuesto. Pero nada diferente de todos los lugares en Cartagena 😂😂😂"

Hotel Casa La Factoria by Faranda Boutique, a member of Radisson Individuals

10/10 Excellent

"The staff is lovely and extremely helpful. The breakfast is amazing and the restaurant serves great food. The rooms are spacious and the beds are super comfortable. The entire atmosphere is calm, warm and welcoming. We look forward to staying here on our next trip to Cartagena."

Hotel Caribe by Faranda Grand, a member of Radisson Individuals

10/10 Excellent

"Staff were friendly and helpful. Housekeeping kept our room clean everyday, just make sure to leave any tip on the bed or with a note or else they won’t take any cash from your room even if it’s laid out on the table near the bed. The animals is what I loved most about the hotel, all of them were friendly and some of them let you pet them. Overall amazing experience here"

GHL Arsenal Hotel

10/10 Excellent

"Loved my stay. Staff were friendly and accommodating. Breakfast was delicious. 10/10 stay I would definitely recommend!"

Terrazas Hotel Boutique

8/10 Good

"Un lugar cómodo, bonito, central, muy limpio y en buen estado. Únicamente a mejorar el desayuno."

Hyatt Regency Cartagena

10/10 Excellent

"Excelente todo muy atento el personal y la comida gratis después de las 4 muy rica"

Mood Matuna Hotel Cartagena

10/10 Excellent

"Stayed here many times now. Love the location. Everyone who works here has been friendly and accommodating. Rooms are always clean. Will continue to book the Mood for future trips."

Soy Local Centro Historico

10/10 Excellent

"El personal tiene que tomar clases de servicio al cliente.....no muy simpático pero casi todos en Cartagenas son Así o tímidos o antipaticos...trabajan sin motivación pero el hotel céntrico , muy buena ubicación y"

Casa Noa Colonial Rooms

10/10 Excellent

"Very good"

Other attractions near Santo Domingo Square

Cartagena Cathedral

9.2/10 (3,019 reviews)

After visiting Cartagena Cathedral, make a plan to see the other sights and activities in Cartagena. Amble around the area's beautiful beaches or seek out the local tours.

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Templo de Santo Domingo

Templo de Santo Domingo is just one of the places to see in Cartagena, so why not enjoy the other things to explore during your travels? Stroll along the beautiful beaches or seek out the local tours.

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Botero's Mujer Reclinada

You can learn about the history of Cartagena with a stop at Botero's Mujer Reclinada. Stroll along the beautiful beaches or seek out the local tours.

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Santo Domingo Church and Monastery

After visiting Santo Domingo Church and Monastery, make a plan to see the other sights and activities in Cartagena. Stroll along the beautiful beaches or seek out the local tours.

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Iglesia de Santo Domingo

After visiting Iglesia de Santo Domingo, make a plan to see the other sights and activities in Cartagena. Stroll along the beautiful beaches or seek out the local tours.

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Palace of the Inquisition Cartagena Historical Museum

8.6/10 (69 reviews)

You can browse the exhibits at Palace of the Inquisition Cartagena Historical Museum, a museum with a story of its own, during your trip to Cartagena. Amble around the area's beautiful beaches or seek out the local tours.

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Bolivar Square

9.2/10 (2,207 reviews)

Find out about the history of Cartagena when you spend time at Bolivar Square. Amble around the area's beautiful beaches or seek out the local tours.

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Plaza de Bolívar

Find out about the history of Cartagena when you take a trip to Plaza de Bolívar. Amble around the area's beautiful beaches or seek out the local tours.

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Frequently asked questions

What's the area like around Santo Domingo Square?

Santo Domingo Square is located in a historic area of Cartagena known for its beautiful beaches. If you're looking for a convenient place to stay, check out the 1199 hotels and other accommodations you'll find within a mile.

Where is the best place to stay near Santo Domingo Square?

Adjacent to Santo Domingo Square, Hotel Voilá Centro Histórico is one of the top choices for your stay based on our traveler data, and this hotel offers 2 outdoor pools and 2 bars. Other good choices within a short distance include Mood Matuna Hotel Cartagena and Osh Hotel Cartagena.

How many hotels can I expect to find close to Santo Domingo Square?

Expedia has 1199 hotels and other accommodations within a mile from Santo Domingo Square.

If I need to cancel the hotel reservation for my stay near Santo Domingo Square, will I receive a refund?

Yes! The majority of room reservations are refundable provided that you cancel before the accommodation's cancellation deadline, which in most cases is within 24 or 48 hours of your scheduled arrival. If you have a non-refundable reservation, you might still have the option to cancel and be given a refund within a 24-hour period of booking. Put your dates in and click on "Search", then use the "fully refundable" filter to review the top deals on offer near Santo Domingo Square.

Where can I learn more about changing or cancelling my trip in the area near Santo Domingo Square?

To access more information about picking new dates or cancelling your stay near Santo Domingo Square, go to https://www.expedia.com/service/.

What can I see and do near Santo Domingo Square?

Study the collections at Palace of the Inquisition Cartagena Historical Museum, Palacio de la Inquisicion, or Cartagena's Gold Museum. Plaza Santo Domingo, San Pedro Claver Church and Convent, and Clock Tower are monuments to see when you're exploring the area around Santo Domingo Square. You can wander around Parque de La Marina, Centenary Park, or La Merced Square if you want a dose of fresh air.

Find hotels near Santo Domingo Square, Cartagena from NT$4,150

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Treat yourself

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Our top choices for Santo Domingo Square hotels

1. Hotel Quadrifolio

2. Casa La Merced by Mustique

3. Casa Baloco

4. Privado Designer Boutique Hotel

5. Casa Belle Cartagena Hotel Boutique

6. Hotel Boutique Casona del Porvenir

7. Palacio del Agua by Faranda Boutique

8. Casa La Cartujita

9. Hotel Casa San Agustin

10. Casa Claver Loft Boutique Hotel

11. Hotel Casona del Colegio

12. Cinco Quintas Hotel Boutique

13. Amarla Boutique Hotel Cartagena

14. Casa Carolina Luxury Wellness Hotel

15. Bastión Luxury Hotel

16. Sophia Hotel By OxoHotel

17. Townhouse Boutique Hotel

18. Hotel Casa del Gobernador

19. Four Seasons Hotel & Residences Cartagena

20. Casa Pestagua Relais Châteaux

Compare popular hotels close to Santo Domingo Square

Top Santo Domingo Square Hotel Reviews

Osh Hotel Cartagena

Hotel Casa La Factoria by Faranda Boutique, a member of Radisson Individuals

Hotel Caribe by Faranda Grand, a member of Radisson Individuals

GHL Arsenal Hotel

Terrazas Hotel Boutique

Hyatt Regency Cartagena

Mood Matuna Hotel Cartagena

Soy Local Centro Historico

Casa Noa Colonial Rooms

Other attractions near Santo Domingo Square

Cartagena Cathedral

Templo de Santo Domingo

Botero's Mujer Reclinada

Santo Domingo Church and Monastery

Iglesia de Santo Domingo

Palace of the Inquisition Cartagena Historical Museum

Bolivar Square

Plaza de Bolívar

Frequently asked questions