Find Luxury Hotels in Santa Cruz Southwest, AZ

Start date: Check-in selected.
To Date
End date: Check-out

    Change your mind

    Book hotels with free cancellation

    Treat yourself

    Sign in to save 10% or more on thousands of hotels

    Be picky

    Search almost a million properties worldwide

Check availability on Santa Cruz Southwest Luxury Hotels

Top Santa Cruz Southwest Luxury Hotels

Top Santa Cruz Southwest Hotel Reviews

Explore a world of travel with Expedia

Frequently asked questions

Are you looking for a luxury hotel for your stay in Santa Cruz Southwest?
Use Expedia to arrange your flight to Tucson International Airport (TUS) airport or Tucson, AZ (AVW-Marana Regional) airport, and then select from a variety of places to stay that will deliver the luxury you want. Amenities are an important consideration when you plan a vacation, so we make it easy to get what you need to make your stay relaxing and comfortable. If you want a posh hotel that has fine dining, a spa, or several swimming pools, Expedia can assist you in finding the best luxury hotel experience that Santa Cruz Southwest has to offer.
What's there to see and do in Santa Cruz Southwest?
Take in the sights and attractions that Santa Cruz Southwest offers with a visit to Tuscon Spectrum, Tucson Museum of Art, and Fox Theatre. If you have extra time while you're in the area, you might want to see Starr Pass Golf Club and Rialto Theatre.