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Our top choices for Roswell Park Comprehensive Cancer Center hotels

A plate of chocolate waffles topped with strawberries and chocolate sauce, served with a scoop of vanilla ice cream.

1. Buffalo Harmony House

Buffalo Harmony House
4.5 star property
Allentown, 1.2 km from Roswell Park Comprehensive Cancer Center
10.0 out of 10, Exceptional, (58 reviews)
"Beautiful place. Great breakfasts. Wonderful staff."
United States
John
The price is NT$10,659
NT$12,396 total
includes taxes & fees
Nov 15 - Nov 16
Buffalo Harmony House
A grand staircase with ornate woodwork and a chandelier, leading to a room with a large wooden door and a stained glass window.

2. InnBuffalo off Elmwood

InnBuffalo off Elmwood
2.5 star property
Elmwood Village, 2.5 km from Roswell Park Comprehensive Cancer Center
10.0 out of 10, Exceptional, (225 reviews)
"Friendly staff, clean and amazing breakfast"
Germany
Terese
The price is NT$4,131
NT$4,740 total
includes taxes & fees
Nov 29 - Nov 30
InnBuffalo off Elmwood
A spacious dining area with a long table, multiple chairs, a chandelier, and a fireplace.

3. The Edward Hotel

The Edward Hotel
3.0 star property
Elmwood Village, 2.3 km from Roswell Park Comprehensive Cancer Center
9.6 out of 10, Exceptional, (272 reviews)
"Great place!"
United States
Noe
The price is NT$4,899
NT$6,745 total
includes taxes & fees
Nov 18 - Nov 19
The Edward Hotel
A hotel room with a large bed, two armchairs, a TV, a fireplace, and a large window with curtains.

4. The Mansion On Delaware Ave

The Mansion On Delaware Ave
4.0 star property
Allentown, 0.8 km from Roswell Park Comprehensive Cancer Center
9.4 out of 10, Exceptional, (1,001 reviews)
"Great place to stay!"
United States
Marilyn
The price is NT$6,480
NT$7,436 total
includes taxes & fees
Dec 10 - Dec 11
The Mansion On Delaware Ave
A modern hotel room with a large window, a sofa, a coffee table, and a TV.

5. Buffalo Marriott at LECOM HARBORCENTER

Buffalo Marriott at LECOM HARBORCENTER
3.5 star property
Downtown Buffalo, 2.6 km from Roswell Park Comprehensive Cancer Center
9.4 out of 10, Exceptional, (992 reviews)
"Great stay"
United States
Stephen
The price is NT$8,255
NT$9,638 total
includes taxes & fees
Dec 13 - Dec 14
Buffalo Marriott at LECOM HARBORCENTER
A two-story building with a white exterior, a red door, and large windows.

6. Buffalo Guesthouse

Buffalo Guesthouse
4.0 star property
Allentown, 0.5 km from Roswell Park Comprehensive Cancer Center
9.4 out of 10, Exceptional, (232 reviews)
"Excellent location and service."
United States
Jose
The price is NT$5,721
NT$6,564 total
includes taxes & fees
Nov 15 - Nov 16
Buffalo Guesthouse
A breakfast buffet with various food items and beverages, a large window with a view of buildings, and a patterned floor.

7. Curtiss Hotel, an Ascend Collection Hotel

Curtiss Hotel, an Ascend Collection Hotel
5.0 star property
Buffalo Theater District, 1.3 km from Roswell Park Comprehensive Cancer Center
9.4 out of 10, Exceptional, (1,002 reviews)
"Loved it, we actually rerouted our return trip home to stay here again :)"
United States
John
The price is NT$8,356
NT$9,755 total
includes taxes & fees
Dec 13 - Dec 14
Curtiss Hotel, an Ascend Collection Hotel
A spacious lobby with modern furniture, large windows, and a high ceiling with exposed beams.

8. The Westin Buffalo

The Westin Buffalo
4.0 star property
Buffalo Theater District, 1.2 km from Roswell Park Comprehensive Cancer Center
9.2 out of 10, Wonderful, (438 reviews)
"Nice brunch"
United States
Sarah
The price is NT$8,961
NT$10,462 total
includes taxes & fees
Nov 23 - Nov 24
The Westin Buffalo
A modern hotel lobby with a bar area, seating, and a large TV screen.

9. Residence Inn by Marriott Buffalo Downtown

Residence Inn by Marriott Buffalo Downtown
3.0 star property
Allentown, 0.7 km from Roswell Park Comprehensive Cancer Center
9.2 out of 10, Wonderful, (390 reviews)
"Spacious room, friendly staff, and great location in Buffalo."
United States
Karen
The price is NT$6,120
NT$7,145 total
includes taxes & fees
Nov 23 - Nov 24
Residence Inn by Marriott Buffalo Downtown
A spacious lobby with a large sofa, a coffee table, and potted plants. There is a decorative wall with a painting and a large window providing natural light.

10. Wyndham Garden Buffalo Downtown

Wyndham Garden Buffalo Downtown
3.0 star property
Downtown Buffalo, 0.2 km from Roswell Park Comprehensive Cancer Center
9.0 out of 10, Wonderful, (1,901 reviews)
"Was a great stay"
United States
Sara
The price is NT$5,190
NT$6,059 total
includes taxes & fees
Nov 23 - Nov 24
Wyndham Garden Buffalo Downtown
A modern outdoor patio with stone walls, a fire feature, and outdoor furniture.

11. Courtyard Buffalo Downtown / Canalside

Courtyard Buffalo Downtown / Canalside
3.0 star property
Downtown Buffalo, 2.4 km from Roswell Park Comprehensive Cancer Center
9.0 out of 10, Wonderful, (1,001 reviews)
"Great location, super friendly staff, great parking -bonus they have a fridge in the room and a microwave"
Canada
Justin
The price is NT$5,573
NT$6,506 total
includes taxes & fees
Nov 29 - Nov 30
Courtyard Buffalo Downtown / Canalside
A hotel with a prominent red sign, large windows, and a parking lot with multiple cars.

12. Hampton Inn & Suites Buffalo Downtown

Hampton Inn & Suites Buffalo Downtown
2.5 star property
Buffalo Theater District, 1.3 km from Roswell Park Comprehensive Cancer Center
8.8 out of 10, Excellent, (1,001 reviews)
"close to all the attractions"
Canada
Scott
The price is NT$5,561
NT$6,493 total
includes taxes & fees
Nov 23 - Nov 24
Hampton Inn & Suites Buffalo Downtown
A hotel room with a bed, desk, chair, TV, and a bathroom with a sink and mirror.

13. Best Western on the Avenue

Best Western on the Avenue
2.5 star property
Allentown, 0.7 km from Roswell Park Comprehensive Cancer Center
8.8 out of 10, Excellent, (1,004 reviews)
"Great place to stay."
United States
James
The price is NT$4,705
NT$5,493 total
includes taxes & fees
Dec 14 - Dec 15
Best Western on the Avenue
A hotel lobby with seating areas, a coffee table, and a lamp.

14. Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG

Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG
2.5 star property
Buffalo Theater District, 1.1 km from Roswell Park Comprehensive Cancer Center
8.6 out of 10, Excellent, (1,002 reviews)
"We liked our stay."
United States
Daniel
The price is NT$3,682
NT$4,299 total
includes taxes & fees
Dec 14 - Dec 15
Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG
An indoor swimming pool with tiled walls, a lifeguard chair, and a pool ladder.

15. Hilton Garden Inn Buffalo Downtown

Hilton Garden Inn Buffalo Downtown
3.0 star property
Buffalo Theater District, 1.5 km from Roswell Park Comprehensive Cancer Center
8.6 out of 10, Excellent, (1,000 reviews)
"The staff was always there and willing to help. Great customer service!!"
United States
Brianne
The price is NT$4,164
NT$4,861 total
includes taxes & fees
Nov 23 - Nov 24
Hilton Garden Inn Buffalo Downtown
A lobby with a staircase, seating area, and a view of the outdoors.

16. Lenox Hotel and Suites

Lenox Hotel and Suites
2.5 star property
Allentown, 0.8 km from Roswell Park Comprehensive Cancer Center
8.2 out of 10, Very good, (136 reviews)
"Enjoyed our stay"
United States
Thomas
The price is NT$2,882
NT$3,307 total
includes taxes & fees
Dec 6 - Dec 7
Lenox Hotel and Suites
A modern hotel with a curved glass facade, a central staircase, and a well-lit interior.

17. Embassy Suites Buffalo

Embassy Suites Buffalo
3.5 star property
Buffalo Theater District, 1.3 km from Roswell Park Comprehensive Cancer Center
8.4 out of 10, Very good, (1,000 reviews)
"I enjoyed my stay"
United States
Laporsche
The price is NT$5,561
NT$6,493 total
includes taxes & fees
Nov 23 - Nov 24
Embassy Suites Buffalo
An indoor swimming pool with clear glass walls, a wooden wall, and a view of buildings outside.

18. Hyatt Regency Buffalo / Hotel and Conference Center

Hyatt Regency Buffalo / Hotel and Conference Center
3.5 star property
Buffalo Theater District, 1.3 km from Roswell Park Comprehensive Cancer Center
8.2 out of 10, Very good, (1,846 reviews)
"Wonderful staff, easy check-in and check-out, great location!"
United States
Eric
The price is NT$5,013
NT$5,852 total
includes taxes & fees
Nov 19 - Nov 20
Hyatt Regency Buffalo / Hotel and Conference Center
A long, ornate hallway with marble walls and a patterned floor, leading to a set of double doors.

19. Hotel at the Lafayette Trademark Collection by Wyndham

Hotel at the Lafayette Trademark Collection by Wyndham
3.5 star property
Buffalo Theater District, 1.6 km from Roswell Park Comprehensive Cancer Center
8.2 out of 10, Very good, (1,004 reviews)
"Great staff and location."
United States
Thomas
The price is NT$4,257
NT$4,970 total
includes taxes & fees
Nov 30 - Dec 1
Hotel at the Lafayette Trademark Collection by Wyndham
A rooftop terrace with wicker furniture, a bar area, and a view of the cityscape.

20. Aloft by Marriott Buffalo Downtown

Aloft by Marriott Buffalo Downtown
3.0 star property
Buffalo Theater District, 0.8 km from Roswell Park Comprehensive Cancer Center
8.2 out of 10, Very good, (371 reviews)
"N/a"
Canada
Nicole
The price is NT$6,023
NT$7,032 total
includes taxes & fees
Nov 23 - Nov 24
Aloft by Marriott Buffalo Downtown
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Compare popular hotels close to Roswell Park Comprehensive Cancer Center

Property
Property class
Guest rating
Breakfast included
Pool
Spa
Pet friendly
WiFi included
A plate of chocolate waffles topped with strawberries and chocolate sauce, served with a scoop of vanilla ice cream.
Buffalo Harmony House
4.5 star property
10.0
Exceptional
58 reviews
View
A grand staircase with ornate woodwork and a chandelier, leading to a room with a large wooden door and a stained glass window.
InnBuffalo off Elmwood
2.5 star property
10.0
Exceptional
225 reviews
View
A spacious dining area with a long table, multiple chairs, a chandelier, and a fireplace.
The Edward Hotel
3.0 star property
9.6
Exceptional
272 reviews
View
A hotel room with a large bed, two armchairs, a TV, a fireplace, and a large window with curtains.
The Mansion On Delaware Ave
4.0 star property
9.4
Exceptional
1,001 reviews
View
A modern hotel room with a large window, a sofa, a coffee table, and a TV.
Buffalo Marriott at LECOM HARBORCENTER
3.5 star property
9.4
Exceptional
992 reviews
View

Other attractions near Roswell Park Comprehensive Cancer Center

Wilcox Mansion - Theodore Roosevelt Inaugural National Historic Site

8.2/10 (144 reviews)
You can browse the exhibits at Wilcox Mansion - Theodore Roosevelt Inaugural National Historic Site, a museum with a storied past, during your trip to Buffalo. Experience the area's entertainment choices and acclaimed theater scene.
See properties

Top Roswell Park Comprehensive Cancer Center Hotel Reviews

A grand staircase with ornate woodwork and a chandelier, leading to a room with a large wooden door and a stained glass window.
InnBuffalo off Elmwood

InnBuffalo off Elmwood

InnBuffalo off Elmwood
Elmwood Village

10/10 Excellent

This property surpassed our expectations. Very comfortable and clean. Everything we needed was available. The available snacks and drinks were a fantastic touch. The house has been preserved beautifully. The outside yard/patio space and front porch were covered and perfect for relaxing. By far one of my favorite stays amongst my travels. Highly recommend.
United States
Lerran
Reviewed August 8, 2026
InnBuffalo off Elmwood

Frequently Asked Questions

What's the area like around Roswell Park Cancer Institute?

Roswell Park Cancer Institute is located in a historic area of Buffalo known for its popular theater scene. If you're looking for a convenient place to stay, check out the 71 hotels and other accommodations you'll find within a mile.

What's the best hotel to stay close to Roswell Park Cancer Institute?

Adjacent to Roswell Park Cancer Institute, Wyndham Garden Buffalo Downtown is one of the top choices for your stay based on our traveler data, and this hotel offers free breakfast and a 24-hour fitness center. Other good choices close by include Hyatt Regency Buffalo / Hotel and Conference Center and Buffalo Guesthouse.

How many hotels will I find near Roswell Park Cancer Institute?

Expedia has 71 hotels and other accommodations within a mile from Roswell Park Cancer Institute.

If I need to cancel the hotel reservation for my stay near Roswell Park Cancer Institute, will I receive a refund?

Yes! Most hotel reservations are refundable if you cancel prior to the accommodation's cancellation deadline, which in most cases is within 24 or 48 hours of your arrival date. If you have a reservation that's non-refundable, it may still be possible to cancel it and receive a refund within 24 hours of booking. Add dates, click "Search", then you can use the "fully refundable" filter to review the top deals on offer near Roswell Park Cancer Institute.

Where can I learn more about changing or cancelling my trip in the area near Roswell Park Cancer Institute?

For more details about changing or cancelling your stay near Roswell Park Cancer Institute, click here.

What can I see and do near Roswell Park Cancer Institute?

You might want to spend some time browsing the exhibits at Buffalo Museum of Science, Buffalo and Erie County Naval and Military Park, or Buffalo AKG Art Museum. Statler Tower, Buffalo Central Terminal, and Peace Bridge are monuments to see when you're exploring the area around Roswell Park Cancer Institute. You can catch a show at Kleinhans Music Hall, Town Ballroom, and Road Less Traveled Productions.

How can I get to Roswell Park Cancer Institute?

With so many transportation options, seeing all of the area near Roswell Park Cancer Institute is easy. Take advantage of metro transit at Fountain Plaza Station, Lafayette Square Station, and Church Station. If you're taking a train into town, Buffalo-Exchange Street Station is the closest stop to Downtown Buffalo.

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